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pes2o-3104116
New maps of development: new visions of maturity. Two modes of moral reasoning are distinguished in boys' and girls' discussions of moral dilemmas: one oriented to justice and rights, one to care and response. These different modes are associated with different forms of self-definition and reflect different images of relationships. The contrasting images of hierarchy and web derive from childhood experiences of inequality and interdependence which give rise to the ideals of justice and of care. The representation of these two lines of development and their interplay yields a new mapping of human growth.
pes2o
{"added":"2018-04-03T02:15:58.092Z","created":"1982-04-01T00:00:00.000Z","id":"32729521","metadata":{"abstract":"Two modes of moral reasoning are distinguished in boys' and girls' discussions of moral dilemmas: one oriented to justice and rights, one to care and response. These different modes are associated with different forms of self-definition and reflect different images of relationships. The contrasting images of hierarchy and web derive from childhood experiences of inequality and interdependence which give rise to the ideals of justice and of care. The representation of these two lines of development and their interplay yields a new mapping of human growth.","abstract_count":86,"abstract_language":"en","abstract_perplexity":-12.558812316754167,"extfieldsofstudy":["Sociology","Medicine"],"provenance":"pes2o_v2-0000.json.gz:3104117","s2fieldsofstudy":["Psychology"],"sha1":"fe7b0c930f335e8368e3f3da0eb9f6eb1e24c926","sources":["Medline","MAG","Unpaywall"],"title":"New maps of development: new visions of maturity.","title_count":8,"title_language":"en","title_perplexity":-14.605785515126088,"top_frequencies":[{"count":13,"token":"of"},{"count":8,"token":"and"},{"count":3,"token":"to"},{"count":3,"token":"different"},{"count":2,"token":"new"},{"count":2,"token":"modes"},{"count":2,"token":"moral"},{"count":2,"token":"are"},{"count":2,"token":"one"},{"count":2,"token":"justice"},{"count":2,"token":"images"},{"count":2,"token":"The"},{"count":1,"token":"New"},{"count":1,"token":"maps"},{"count":1,"token":"development:"},{"count":1,"token":"visions"},{"count":1,"token":"maturity."},{"count":1,"token":"Two"},{"count":1,"token":"reasoning"},{"count":1,"token":"distinguished"},{"count":1,"token":"in"},{"count":1,"token":"boys'"},{"count":1,"token":"girls'"},{"count":1,"token":"discussions"},{"count":1,"token":"dilemmas:"},{"count":1,"token":"oriented"},{"count":1,"token":"rights,"},{"count":1,"token":"care"},{"count":1,"token":"response."},{"count":1,"token":"These"},{"count":1,"token":"associated"},{"count":1,"token":"with"},{"count":1,"token":"forms"},{"count":1,"token":"self-definition"},{"count":1,"token":"reflect"},{"count":1,"token":"relationships."},{"count":1,"token":"contrasting"},{"count":1,"token":"hierarchy"},{"count":1,"token":"web"},{"count":1,"token":"derive"},{"count":1,"token":"from"},{"count":1,"token":"childhood"},{"count":1,"token":"experiences"},{"count":1,"token":"inequality"},{"count":1,"token":"interdependence"},{"count":1,"token":"which"},{"count":1,"token":"give"},{"count":1,"token":"rise"},{"count":1,"token":"the"},{"count":1,"token":"ideals"},{"count":1,"token":"care."},{"count":1,"token":"representation"},{"count":1,"token":"these"},{"count":1,"token":"two"},{"count":1,"token":"lines"},{"count":1,"token":"development"},{"count":1,"token":"their"},{"count":1,"token":"interplay"},{"count":1,"token":"yields"},{"count":1,"token":"a"},{"count":1,"token":"mapping"},{"count":1,"token":"human"},{"count":1,"token":"growth."}],"year":1982},"source":"s2","version":"v3-fos"}
110
dclm-428943317
8 Surprising Uses For Sheds Daimler's "Illegal Mint" Little did Gottlieb Daimler know that while he was toiling the hours in an extension to his greenhouse working on the world's first lightweight four-stroke internal combustion engine that Karl and Berthe Benz were doing the same in their shed. Daimler and fellow inventor Wilhelm Maybach widened the garden path that led to the makeshift workshop at the bottom of the garden so that vehicles could be wheeled down to it. Their work was carried out in such secrecy in this remote garden building (servants were not allowed inside) that he was reported to the police for installing an illegal mint. Today, you might need one of those to afford a Maybach.
dclm
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160
pes2o-27493322
Trampling the sacred: multicultural education as pedagogical racism The following paper is a critical examination involving the misuse of sacred cultural tools and practices in the name of multicultural education. Native American practices are identified to illustrate how such inappropriate usages promote pedagogical racism. The misuse continues the hegemonic distribution of social capital. Through the irresponsible portrayal of complex and sophisticated cultures, American education continues to perpetuate pedagogical violence against children who are already socially and educationally disenfranchised. Using Freire, Giroux, Deloria, and Grande, this paper will identify strategies of communication and education necessary to eliminate pedagogical racism and begin to reverse the violence against children.
pes2o
{"added":"2019-05-06T14:08:33.569Z","created":"2012-10-15T00:00:00.000Z","id":"145112508","metadata":{"abstract":"The following paper is a critical examination involving the misuse of sacred cultural tools and practices in the name of multicultural education. Native American practices are identified to illustrate how such inappropriate usages promote pedagogical racism. The misuse continues the hegemonic distribution of social capital. Through the irresponsible portrayal of complex and sophisticated cultures, American education continues to perpetuate pedagogical violence against children who are already socially and educationally disenfranchised. Using Freire, Giroux, Deloria, and Grande, this paper will identify strategies of communication and education necessary to eliminate pedagogical racism and begin to reverse the violence against children.","abstract_count":98,"abstract_language":"en","abstract_perplexity":-13.82326843421274,"extfieldsofstudy":["Sociology"],"provenance":"pes2o_v2-0007.json.gz:386726","s2fieldsofstudy":["Education"],"sha1":"13c3fa052f20e70062bb516e61bc6761a293b06b","sources":["MergedPDFExtraction","TaylorAndFrancis","MAG","Unpaywall"],"title":"Trampling the sacred: multicultural education as pedagogical racism","title_count":8,"title_language":"en","title_perplexity":-15.882341022745788,"top_frequencies":[{"count":6,"token":"the"},{"count":6,"token":"and"},{"count":5,"token":"of"},{"count":4,"token":"pedagogical"},{"count":4,"token":"to"},{"count":3,"token":"education"},{"count":2,"token":"multicultural"},{"count":2,"token":"racism"},{"count":2,"token":"The"},{"count":2,"token":"paper"},{"count":2,"token":"misuse"},{"count":2,"token":"practices"},{"count":2,"token":"American"},{"count":2,"token":"are"},{"count":2,"token":"continues"},{"count":2,"token":"violence"},{"count":2,"token":"against"},{"count":1,"token":"Trampling"},{"count":1,"token":"sacred:"},{"count":1,"token":"as"},{"count":1,"token":"following"},{"count":1,"token":"is"},{"count":1,"token":"a"},{"count":1,"token":"critical"},{"count":1,"token":"examination"},{"count":1,"token":"involving"},{"count":1,"token":"sacred"},{"count":1,"token":"cultural"},{"count":1,"token":"tools"},{"count":1,"token":"in"},{"count":1,"token":"name"},{"count":1,"token":"education."},{"count":1,"token":"Native"},{"count":1,"token":"identified"},{"count":1,"token":"illustrate"},{"count":1,"token":"how"},{"count":1,"token":"such"},{"count":1,"token":"inappropriate"},{"count":1,"token":"usages"},{"count":1,"token":"promote"},{"count":1,"token":"racism."},{"count":1,"token":"hegemonic"},{"count":1,"token":"distribution"},{"count":1,"token":"social"},{"count":1,"token":"capital."},{"count":1,"token":"Through"},{"count":1,"token":"irresponsible"},{"count":1,"token":"portrayal"},{"count":1,"token":"complex"},{"count":1,"token":"sophisticated"},{"count":1,"token":"cultures,"},{"count":1,"token":"perpetuate"},{"count":1,"token":"children"},{"count":1,"token":"who"},{"count":1,"token":"already"},{"count":1,"token":"socially"},{"count":1,"token":"educationally"},{"count":1,"token":"disenfranchised."},{"count":1,"token":"Using"},{"count":1,"token":"Freire,"},{"count":1,"token":"Giroux,"},{"count":1,"token":"Deloria,"},{"count":1,"token":"Grande,"},{"count":1,"token":"this"},{"count":1,"token":"will"},{"count":1,"token":"identify"},{"count":1,"token":"strategies"},{"count":1,"token":"communication"},{"count":1,"token":"necessary"},{"count":1,"token":"eliminate"},{"count":1,"token":"begin"},{"count":1,"token":"reverse"},{"count":1,"token":"children."}],"year":2012},"source":"s2","version":"v3-fos"}
145
pes2o-7210752
Effect of Polyphenol Oxidase(PPO) Enzymatic Inducing Factors on Non-enzymatic Browning of Apple Polyphenols In order to study the effects of apple polyphenol oxidase(PPO) enzymatic inducing factors on the non-enzymatic browning of apple polyphenols, chlorogenic acid and phlorizin were used as reaction substrates, and phosphate buffer was used as the model apple juice system to carry out enzymatic induction under controlled enzymatic induction conditions. Subsequently, the enzyme was deactivated, and the non-enzymatic polymerization in the model apple juice system was carried out at 60 ℃; L*, a*, b*, and △E* values were measured using a colorimeter every 24 h. The results showed that significant differences were found in the impacts of enzymatic inducing factors on the non-enzymatic browning involving chlorogenic acid and phlorizin. In the 3.5~6.0 p H range, the degree of browning in the model juice system containing chlorogenic acid and phlorizin increased with increasing p H values. When the temperature of enzymatic induction was between 20 and 60 ℃, the temperature of the inducing system had no significant effect on the non-enzymatic browning involving chlorogenic acid, while the degree of non-enzymatic browning in the model juice using phlorizin was higher at 40 ℃. A higher degree of non-enzymatic browning was achieved for the model juice using chlorogenic acid and phlorizin when the durations of enzymatic induction were 40 and 30 min, respectively. When the PPO activity was in the range of 14.25~171 U, the increasing enzymatic activity could accelerate the non-enzymatic browning involving chlorogenic acid and phlorizin. Meanwhile, the results indicated that non-enzymatic browning involving phlorizin was related to the haze occurring in apple juice, and the development of the haze in apple juice could be accelerated by increasing the p H, temperature, PPO activities, and duration of enzymatic induction.
pes2o
{"added":"2019-03-31T13:48:06.937Z","created":"2015-01-01T00:00:00.000Z","id":"88257632","metadata":{"abstract":"In order to study the effects of apple polyphenol oxidase(PPO) enzymatic inducing factors on the non-enzymatic browning of apple polyphenols, chlorogenic acid and phlorizin were used as reaction substrates, and phosphate buffer was used as the model apple juice system to carry out enzymatic induction under controlled enzymatic induction conditions. Subsequently, the enzyme was deactivated, and the non-enzymatic polymerization in the model apple juice system was carried out at 60 \u2103; L*, a*, b*, and \u25b3E* values were measured using a colorimeter every 24 h. The results showed that significant differences were found in the impacts of enzymatic inducing factors on the non-enzymatic browning involving chlorogenic acid and phlorizin. In the 3.5~6.0 p H range, the degree of browning in the model juice system containing chlorogenic acid and phlorizin increased with increasing p H values. When the temperature of enzymatic induction was between 20 and 60 \u2103, the temperature of the inducing system had no significant effect on the non-enzymatic browning involving chlorogenic acid, while the degree of non-enzymatic browning in the model juice using phlorizin was higher at 40 \u2103. A higher degree of non-enzymatic browning was achieved for the model juice using chlorogenic acid and phlorizin when the durations of enzymatic induction were 40 and 30 min, respectively. When the PPO activity was in the range of 14.25~171 U, the increasing enzymatic activity could accelerate the non-enzymatic browning involving chlorogenic acid and phlorizin. Meanwhile, the results indicated that non-enzymatic browning involving phlorizin was related to the haze occurring in apple juice, and the development of the haze in apple juice could be accelerated by increasing the p H, temperature, PPO activities, and duration of enzymatic induction.","abstract_count":278,"abstract_language":"en","abstract_perplexity":-15.399023362733145,"extfieldsofstudy":["Chemistry"],"provenance":"pes2o_v2-0001.json.gz:3348221","s2fieldsofstudy":["Agricultural And Food Sciences"],"sha1":"34965dbb65c555b00decc4eac9519617445b377f","sources":["MAG"],"title":"Effect of Polyphenol Oxidase(PPO) Enzymatic Inducing Factors on Non-enzymatic Browning of Apple Polyphenols","title_count":13,"title_language":"en","title_perplexity":-17.751306675764898,"top_frequencies":[{"count":28,"token":"the"},{"count":14,"token":"of"},{"count":12,"token":"and"},{"count":8,"token":"enzymatic"},{"count":8,"token":"non-enzymatic"},{"count":8,"token":"browning"},{"count":8,"token":"was"},{"count":7,"token":"in"},{"count":6,"token":"apple"},{"count":6,"token":"chlorogenic"},{"count":6,"token":"juice"},{"count":5,"token":"acid"},{"count":5,"token":"phlorizin"},{"count":5,"token":"model"},{"count":4,"token":"on"},{"count":4,"token":"were"},{"count":4,"token":"system"},{"count":4,"token":"induction"},{"count":4,"token":"involving"},{"count":3,"token":"to"},{"count":3,"token":"inducing"},{"count":3,"token":"using"},{"count":3,"token":"p"},{"count":3,"token":"degree"},{"count":3,"token":"increasing"},{"count":2,"token":"In"},{"count":2,"token":"factors"},{"count":2,"token":"used"},{"count":2,"token":"as"},{"count":2,"token":"out"},{"count":2,"token":"at"},{"count":2,"token":"60"},{"count":2,"token":"results"},{"count":2,"token":"that"},{"count":2,"token":"significant"},{"count":2,"token":"phlorizin."},{"count":2,"token":"H"},{"count":2,"token":"When"},{"count":2,"token":"temperature"},{"count":2,"token":"higher"},{"count":2,"token":"40"},{"count":2,"token":"PPO"},{"count":2,"token":"activity"},{"count":2,"token":"could"},{"count":2,"token":"haze"},{"count":1,"token":"Effect"},{"count":1,"token":"Polyphenol"},{"count":1,"token":"Oxidase(PPO)"},{"count":1,"token":"Enzymatic"},{"count":1,"token":"Inducing"},{"count":1,"token":"Factors"},{"count":1,"token":"Non-enzymatic"},{"count":1,"token":"Browning"},{"count":1,"token":"Apple"},{"count":1,"token":"Polyphenols"},{"count":1,"token":"order"},{"count":1,"token":"study"},{"count":1,"token":"effects"},{"count":1,"token":"polyphenol"},{"count":1,"token":"oxidase(PPO)"},{"count":1,"token":"polyphenols,"},{"count":1,"token":"reaction"},{"count":1,"token":"substrates,"},{"count":1,"token":"phosphate"},{"count":1,"token":"buffer"},{"count":1,"token":"carry"},{"count":1,"token":"under"},{"count":1,"token":"controlled"},{"count":1,"token":"conditions."},{"count":1,"token":"Subsequently,"},{"count":1,"token":"enzyme"},{"count":1,"token":"deactivated,"},{"count":1,"token":"polymerization"},{"count":1,"token":"carried"},{"count":1,"token":"\u2103;"},{"count":1,"token":"L*,"},{"count":1,"token":"a*,"},{"count":1,"token":"b*,"},{"count":1,"token":"\u25b3E*"},{"count":1,"token":"values"},{"count":1,"token":"measured"},{"count":1,"token":"a"},{"count":1,"token":"colorimeter"},{"count":1,"token":"every"},{"count":1,"token":"24"},{"count":1,"token":"h."},{"count":1,"token":"The"},{"count":1,"token":"showed"},{"count":1,"token":"differences"},{"count":1,"token":"found"},{"count":1,"token":"impacts"},{"count":1,"token":"3.5~6.0"},{"count":1,"token":"range,"},{"count":1,"token":"containing"},{"count":1,"token":"increased"},{"count":1,"token":"with"},{"count":1,"token":"values."},{"count":1,"token":"between"},{"count":1,"token":"20"},{"count":1,"token":"\u2103,"}],"year":2015},"source":"s2","version":"v3-fos"}
439
flan-9107048
question: the u.n. agency for palestinian refugees said friday that it has halted all aid shipments into the gaza strip due to interference by the ruling hamas militant group . Write a brief summary in a sentence or so. summary: un halts aid to gaza cites hamas disruption question: with two acquisitions already this year , rbc centura might be on the prowl for more . Write a brief summary in a sentence or so. summary: analysts want more from rbc centura question: the nba 's instant replay system was an instant success this season . Write a brief summary in a sentence or so. summary: nba will go to instant replay again question: the french lower house narrowly approved draft legislation on wednesday that would further loosen rules -- cherished by many traditionalists -- that restrict commercial activity on sundays . Write a brief summary in a sentence or so. summary: french bill advances to open shops on sunday
flan
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218
flan-8066869
How is "Recital C of the resolution rightly points the finger at the economic considerations which led to the year being displayed as two digits only." said in German? In der Entschließung wird zu Recht in Erwägung C auf die wirtschaftlichen Beweggründe hingewiesen, die zur Kürzung der Jahreszahl auf zwei Ziffern geführt haben. How is "Subject: Security in Cyprus Given that the EU, and some Member States in particular, had raised objections to the initial plan of the Cyprus Government to site a surface-to-air missile system, consisting of S-300 missiles, on the island and subsequently congratulated it on its decision to cancel the plan, how does the Commission feel that Cyprus should improve its security?" said in German? Betrifft: Sicherheit auf Zypern Die EU - und einige Mitgliedstaaten im besonderen - hatten Bedenken erhoben gegen den ursprünglichen Plan der Regierung Zyperns, ein System für Boden-Luft-Flugkörper, bestehend aus 300 Flugkörpern, auf der Insel zu stationieren, und haben Zypern anschließend zu seinem Beschluß gratuliert, doch wieder von diesem Vorhaben Abstand zu nehmen. Wie sollte Zypern nun nach Auffassung der Kommission seine Sicherheit verbessern? How is "I am not in favour of nominalism." said in German? Ich bin nicht für Nominalismus. How is "is an Amsterdam-born historian, who took part in most highlights of the Sixties as a student leader." said in German? Nachher, entwickelte er das erste holländische Stadtviertelerneuerungsprogramm aus Sicht der Immigration von Gastarbeitern und ihren Familien und führte dessen Umsetzung in den achzigern Jahren in 16 Städten und 32 Vierteln im Auftage der niederländischen Regierung. Die holländische Erfahrungen wurden von ihm in den neunzigern Jahren beigetragen an den 'urban' Programmen der EU Kommission.
flan
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512
pes2o-21589652
Design and structure-activity relationships of potent and selective inhibitors of blood coagulation factor Xa. The discovery of a series of non-peptide factor Xa (FXa) inhibitors incorporating 3-(S)-amino-2-pyrrolidinone as a central template is described. After identifying compound 4, improvements in in vitro potency involved modifications of the liphophilic group and optimizing the angle of presentation of the amidine group to the S1 pocket of FXa. These studies ultimately led to compound RPR120844, a potent inhibitor of FXa (K(i) = 7 nM) which shows selectivity for FXa over trypsin, thrombin, and several fibrinolytic serine proteinases. RPR120844 is an effective anticoagulant in both the rat model of FeCl(2)-induced carotid artery thrombosis and the rabbit model of jugular vein thrombus formation.
pes2o
{"added":"2018-04-03T00:48:17.934Z","created":"1999-08-21T00:00:00.000Z","id":"24796057","metadata":{"abstract":"The discovery of a series of non-peptide factor Xa (FXa) inhibitors incorporating 3-(S)-amino-2-pyrrolidinone as a central template is described. After identifying compound 4, improvements in in vitro potency involved modifications of the liphophilic group and optimizing the angle of presentation of the amidine group to the S1 pocket of FXa. These studies ultimately led to compound RPR120844, a potent inhibitor of FXa (K(i) = 7 nM) which shows selectivity for FXa over trypsin, thrombin, and several fibrinolytic serine proteinases. RPR120844 is an effective anticoagulant in both the rat model of FeCl(2)-induced carotid artery thrombosis and the rabbit model of jugular vein thrombus formation.","abstract_count":103,"abstract_language":"en","abstract_perplexity":-17.273441993135894,"extfieldsofstudy":["Chemistry","Medicine"],"provenance":"pes2o_v2-0005.json.gz:2226917","s2fieldsofstudy":["Biology","Chemistry"],"sha1":"e857e467e51f0b2d3e9dea30b913ca2693b2d964","sources":["Unpaywall","Medline","MAG"],"title":"Design and structure-activity relationships of potent and selective inhibitors of blood coagulation factor Xa.","title_count":14,"title_language":"en","title_perplexity":-14.68946210474865,"top_frequencies":[{"count":11,"token":"of"},{"count":6,"token":"the"},{"count":5,"token":"and"},{"count":3,"token":"a"},{"count":3,"token":"in"},{"count":2,"token":"potent"},{"count":2,"token":"inhibitors"},{"count":2,"token":"factor"},{"count":2,"token":"is"},{"count":2,"token":"compound"},{"count":2,"token":"group"},{"count":2,"token":"to"},{"count":2,"token":"FXa"},{"count":2,"token":"model"},{"count":1,"token":"Design"},{"count":1,"token":"structure-activity"},{"count":1,"token":"relationships"},{"count":1,"token":"selective"},{"count":1,"token":"blood"},{"count":1,"token":"coagulation"},{"count":1,"token":"Xa."},{"count":1,"token":"The"},{"count":1,"token":"discovery"},{"count":1,"token":"series"},{"count":1,"token":"non-peptide"},{"count":1,"token":"Xa"},{"count":1,"token":"(FXa)"},{"count":1,"token":"incorporating"},{"count":1,"token":"3-(S)-amino-2-pyrrolidinone"},{"count":1,"token":"as"},{"count":1,"token":"central"},{"count":1,"token":"template"},{"count":1,"token":"described."},{"count":1,"token":"After"},{"count":1,"token":"identifying"},{"count":1,"token":"4,"},{"count":1,"token":"improvements"},{"count":1,"token":"vitro"},{"count":1,"token":"potency"},{"count":1,"token":"involved"},{"count":1,"token":"modifications"},{"count":1,"token":"liphophilic"},{"count":1,"token":"optimizing"},{"count":1,"token":"angle"},{"count":1,"token":"presentation"},{"count":1,"token":"amidine"},{"count":1,"token":"S1"},{"count":1,"token":"pocket"},{"count":1,"token":"FXa."},{"count":1,"token":"These"},{"count":1,"token":"studies"},{"count":1,"token":"ultimately"},{"count":1,"token":"led"},{"count":1,"token":"RPR120844,"},{"count":1,"token":"inhibitor"},{"count":1,"token":"(K(i)"},{"count":1,"token":"="},{"count":1,"token":"7"},{"count":1,"token":"nM)"},{"count":1,"token":"which"},{"count":1,"token":"shows"},{"count":1,"token":"selectivity"},{"count":1,"token":"for"},{"count":1,"token":"over"},{"count":1,"token":"trypsin,"},{"count":1,"token":"thrombin,"},{"count":1,"token":"several"},{"count":1,"token":"fibrinolytic"},{"count":1,"token":"serine"},{"count":1,"token":"proteinases."},{"count":1,"token":"RPR120844"},{"count":1,"token":"an"},{"count":1,"token":"effective"},{"count":1,"token":"anticoagulant"},{"count":1,"token":"both"},{"count":1,"token":"rat"},{"count":1,"token":"FeCl(2)-induced"},{"count":1,"token":"carotid"},{"count":1,"token":"artery"},{"count":1,"token":"thrombosis"},{"count":1,"token":"rabbit"},{"count":1,"token":"jugular"},{"count":1,"token":"vein"},{"count":1,"token":"thrombus"},{"count":1,"token":"formation."}],"year":1999},"source":"s2","version":"v3-fos"}
180
pes2o-10923173
The 3s2 3p5 → 3s3p5 (3P)np series in Cl I The photoabsorption spectrum of neutral chlorine has been photographed for the first time in the wavelength region 400-700 Å, the absorbing atomic vapour being produced by means of the flash-pyrolysis technique. Nine autoionizing resonances have been observed and identified as forming a series arising from the excitation of the inner 3s electron. The agreement with theoretical results is discussed.
pes2o
{"added":"2022-07-22T06:40:39.893Z","created":"1991-01-01T00:00:00.000Z","id":"250872013","metadata":{"abstract":"The photoabsorption spectrum of neutral chlorine has been photographed for the first time in the wavelength region 400-700 \u00c5, the absorbing atomic vapour being produced by means of the flash-pyrolysis technique. Nine autoionizing resonances have been observed and identified as forming a series arising from the excitation of the inner 3s electron. The agreement with theoretical results is discussed.","abstract_count":59,"abstract_language":"en","abstract_perplexity":-14.637748124324244,"extfieldsofstudy":["Physics"],"provenance":"pes2o_v2-0002.json.gz:3183972","s2fieldsofstudy":["Physics"],"sha1":"44c2983ab1f66ce41e268c2945f9b99ffae69baa","sources":["ScienceParsePlus","IOP","MergedPDFExtraction"],"title":"The 3s2 3p5 \u2192 3s3p5 (3P)np series in Cl I","title_count":10,"title_language":"en","title_perplexity":-20.858869410267555,"top_frequencies":[{"count":6,"token":"the"},{"count":3,"token":"The"},{"count":3,"token":"of"},{"count":2,"token":"series"},{"count":2,"token":"in"},{"count":2,"token":"been"},{"count":1,"token":"3s2"},{"count":1,"token":"3p5"},{"count":1,"token":"\u2192"},{"count":1,"token":"3s3p5"},{"count":1,"token":"(3P)np"},{"count":1,"token":"Cl"},{"count":1,"token":"I"},{"count":1,"token":"photoabsorption"},{"count":1,"token":"spectrum"},{"count":1,"token":"neutral"},{"count":1,"token":"chlorine"},{"count":1,"token":"has"},{"count":1,"token":"photographed"},{"count":1,"token":"for"},{"count":1,"token":"first"},{"count":1,"token":"time"},{"count":1,"token":"wavelength"},{"count":1,"token":"region"},{"count":1,"token":"400-700"},{"count":1,"token":"\u00c5,"},{"count":1,"token":"absorbing"},{"count":1,"token":"atomic"},{"count":1,"token":"vapour"},{"count":1,"token":"being"},{"count":1,"token":"produced"},{"count":1,"token":"by"},{"count":1,"token":"means"},{"count":1,"token":"flash-pyrolysis"},{"count":1,"token":"technique."},{"count":1,"token":"Nine"},{"count":1,"token":"autoionizing"},{"count":1,"token":"resonances"},{"count":1,"token":"have"},{"count":1,"token":"observed"},{"count":1,"token":"and"},{"count":1,"token":"identified"},{"count":1,"token":"as"},{"count":1,"token":"forming"},{"count":1,"token":"a"},{"count":1,"token":"arising"},{"count":1,"token":"from"},{"count":1,"token":"excitation"},{"count":1,"token":"inner"},{"count":1,"token":"3s"},{"count":1,"token":"electron."},{"count":1,"token":"agreement"},{"count":1,"token":"with"},{"count":1,"token":"theoretical"},{"count":1,"token":"results"},{"count":1,"token":"is"},{"count":1,"token":"discussed."}],"year":1991},"source":"s2","version":"v3-fos"}
99
pes2o-2838005
NF-κB signaling is increased in HD3 cells following exposure to 1,4-benzoquinone: role of reactive oxygen species and p38-MAPK. In utero exposure to benzene, a known environmental contaminant, is associated with increased risk of leukemia. We have previously shown that in utero benzene exposure can alter the redox-sensitive transcription factor NF-κB, and we hypothesize that this is through benzene-induced reactive oxygen species (ROS) production interfering with the signaling pathway involving NF-κB and p38-Mitogen Activated Protein Kinase (MAPK). As benzoquinone (BQ) is one of benzene's most toxic metabolites, the objectives of this study were to determine whether ROS and p38-MAPK-mediated BQ-induced increased NF-κB activity. HD3 chicken erythroblast cells were transfected with an NF-κB luciferase-linked reporter plasmid and exposed to BQ (25 μM) for 2-24 h. NF-κB activities were determined through luciferase assays; Western blotting was conducted to assess changes in protein levels in nontransfected cells; and the presence of ROS was determined via 2',7'-dichlorodihydrofluorescein diacetate (DCFDA) flow cytometric assays. Results demonstrated that NF-κB activity was significantly increased following exposure to BQ for 16 and 24 h and DCFDA assays and pretreatment with antioxidants indicated that BQ-mediated ROS production was responsible for this increase. Furthermore, decreased inhibitor of kappaB-alpha (IκB-α) expression suggests that nuclear factor-kappaB (NF-κB) translocates into the nucleus and that p38-MAPK activation through a ROS-dependent pathway mediates BQ-mediated increases in NF-κB activity. Future studies investigating the role of p38-MAPK in this pathway are warranted. Evaluating the effects of toxicant exposure on cell signaling pathways is vital for understanding mechanisms of xenobiotic-induced toxicity.
pes2o
{"added":"2018-04-03T04:28:46.992Z","created":"2014-02-01T00:00:00.000Z","id":"39078690","metadata":{"abstract":"In utero exposure to benzene, a known environmental contaminant, is associated with increased risk of leukemia. We have previously shown that in utero benzene exposure can alter the redox-sensitive transcription factor NF-\u03baB, and we hypothesize that this is through benzene-induced reactive oxygen species (ROS) production interfering with the signaling pathway involving NF-\u03baB and p38-Mitogen Activated Protein Kinase (MAPK). As benzoquinone (BQ) is one of benzene's most toxic metabolites, the objectives of this study were to determine whether ROS and p38-MAPK-mediated BQ-induced increased NF-\u03baB activity. HD3 chicken erythroblast cells were transfected with an NF-\u03baB luciferase-linked reporter plasmid and exposed to BQ (25 \u03bcM) for 2-24 h. NF-\u03baB activities were determined through luciferase assays; Western blotting was conducted to assess changes in protein levels in nontransfected cells; and the presence of ROS was determined via 2',7'-dichlorodihydrofluorescein diacetate (DCFDA) flow cytometric assays. Results demonstrated that NF-\u03baB activity was significantly increased following exposure to BQ for 16 and 24 h and DCFDA assays and pretreatment with antioxidants indicated that BQ-mediated ROS production was responsible for this increase. Furthermore, decreased inhibitor of kappaB-alpha (I\u03baB-\u03b1) expression suggests that nuclear factor-kappaB (NF-\u03baB) translocates into the nucleus and that p38-MAPK activation through a ROS-dependent pathway mediates BQ-mediated increases in NF-\u03baB activity. Future studies investigating the role of p38-MAPK in this pathway are warranted. Evaluating the effects of toxicant exposure on cell signaling pathways is vital for understanding mechanisms of xenobiotic-induced toxicity.","abstract_count":233,"abstract_language":"en","abstract_perplexity":-17.725082047785335,"extfieldsofstudy":["Medicine","Biology"],"provenance":"pes2o_v2-0000.json.gz:2838006","s2fieldsofstudy":["Biology"],"sha1":"11a532bf4baddaad22ed7301deee3aee6efaa944","sources":["ScienceParsePlus","Medline","Adhoc","MergedPDFExtraction","Unpaywall","MAG"],"title":"NF-\u03baB signaling is increased in HD3 cells following exposure to 1,4-benzoquinone: role of reactive oxygen species and p38-MAPK.","title_count":18,"title_language":"en","title_perplexity":-19.690850403055975,"top_frequencies":[{"count":10,"token":"and"},{"count":9,"token":"of"},{"count":7,"token":"NF-\u03baB"},{"count":7,"token":"the"},{"count":6,"token":"in"},{"count":6,"token":"to"},{"count":6,"token":"that"},{"count":5,"token":"is"},{"count":5,"token":"exposure"},{"count":4,"token":"increased"},{"count":4,"token":"with"},{"count":4,"token":"this"},{"count":4,"token":"for"},{"count":4,"token":"was"},{"count":3,"token":"signaling"},{"count":3,"token":"through"},{"count":3,"token":"pathway"},{"count":3,"token":"were"},{"count":3,"token":"ROS"},{"count":2,"token":"HD3"},{"count":2,"token":"cells"},{"count":2,"token":"following"},{"count":2,"token":"role"},{"count":2,"token":"reactive"},{"count":2,"token":"oxygen"},{"count":2,"token":"species"},{"count":2,"token":"utero"},{"count":2,"token":"a"},{"count":2,"token":"production"},{"count":2,"token":"activity."},{"count":2,"token":"BQ"},{"count":2,"token":"determined"},{"count":2,"token":"BQ-mediated"},{"count":2,"token":"p38-MAPK"},{"count":1,"token":"1,4-benzoquinone:"},{"count":1,"token":"p38-MAPK."},{"count":1,"token":"In"},{"count":1,"token":"benzene,"},{"count":1,"token":"known"},{"count":1,"token":"environmental"},{"count":1,"token":"contaminant,"},{"count":1,"token":"associated"},{"count":1,"token":"risk"},{"count":1,"token":"leukemia."},{"count":1,"token":"We"},{"count":1,"token":"have"},{"count":1,"token":"previously"},{"count":1,"token":"shown"},{"count":1,"token":"benzene"},{"count":1,"token":"can"},{"count":1,"token":"alter"},{"count":1,"token":"redox-sensitive"},{"count":1,"token":"transcription"},{"count":1,"token":"factor"},{"count":1,"token":"NF-\u03baB,"},{"count":1,"token":"we"},{"count":1,"token":"hypothesize"},{"count":1,"token":"benzene-induced"},{"count":1,"token":"(ROS)"},{"count":1,"token":"interfering"},{"count":1,"token":"involving"},{"count":1,"token":"p38-Mitogen"},{"count":1,"token":"Activated"},{"count":1,"token":"Protein"},{"count":1,"token":"Kinase"},{"count":1,"token":"(MAPK)."},{"count":1,"token":"As"},{"count":1,"token":"benzoquinone"},{"count":1,"token":"(BQ)"},{"count":1,"token":"one"},{"count":1,"token":"benzene's"},{"count":1,"token":"most"},{"count":1,"token":"toxic"},{"count":1,"token":"metabolites,"},{"count":1,"token":"objectives"},{"count":1,"token":"study"},{"count":1,"token":"determine"},{"count":1,"token":"whether"},{"count":1,"token":"p38-MAPK-mediated"},{"count":1,"token":"BQ-induced"},{"count":1,"token":"chicken"},{"count":1,"token":"erythroblast"},{"count":1,"token":"transfected"},{"count":1,"token":"an"},{"count":1,"token":"luciferase-linked"},{"count":1,"token":"reporter"},{"count":1,"token":"plasmid"},{"count":1,"token":"exposed"},{"count":1,"token":"(25"},{"count":1,"token":"\u03bcM)"},{"count":1,"token":"2-24"},{"count":1,"token":"h."},{"count":1,"token":"activities"},{"count":1,"token":"luciferase"},{"count":1,"token":"assays;"},{"count":1,"token":"Western"},{"count":1,"token":"blotting"},{"count":1,"token":"conducted"},{"count":1,"token":"assess"},{"count":1,"token":"changes"}],"year":2014},"source":"s2","version":"v3-fos"}
407
wikipedia-5048603
New Slaves "New Slaves" is a song by American hip hop recording artist Kanye West, from his sixth studio album "Yeezus" (2013). It was produced primarily by West, with additional production by Ben Bronfman, Mike Dean, Travis Scott, Noah Goldstein, Sham Joseph, and Che Pope. The song's lyrics discuss slavery and segregation, as well as racism in general, materialism, and stereotypes of African Americans in the United States. It features vocals from American recording artist Frank Ocean, whom West previously collaborated with on "Watch the Throne" (2011). The song's coda features a sample of "Gyöngyhajú lány" by Hungarian composer Gábor Presser, who later sued West in 2016 over its use. Before its release on the album, West promoted it extensively, projecting it on over 60 locations around the world, and performing it live on "Saturday Night Live" and at the "Later... With Jools Holland". Since release, the song has received widespread acclaim from music critics, with many praising its message, sample, and Ocean's appearance. Despite not being released as a single, the song charted in Canada, France, the United Kingdom, and the United States in 2013. It was nominated for Best Rap Song at the 56th Annual Grammy Awards and appeared on several year-end lists. West later performed the song on The Yeezus Tour. Background. In a 2014 interview with Zach Baron of "GQ", West claimed to have engaged in numerous meetings that included what he dubbed as "Stay in your place" type conversations. They were described as what lead him "to the point of creating 'New Slaves' and 'Blood on the Leaves' and the entire "Yeezus" album, and to make the album basically like a protest in music." The track samples "HBA War" by Dutch E Germ; "Yeezus" production consultant Arca introduced West to the track. The conclusion of "New Slaves" features Ocean singing over a sample of "Gyöngyhajú lány" (1969) by Hungarian rock band Omega. In 2016, Hungarian composer Gábor Presser, who wrote "Gyöngyhajú lány" in 1969, claimed that West asked him for permission to use that composition as the outro of "New Slaves", and gave him a $10,000 check as a deposit toward a future agreement. The check was not cashed, and Presser filed a lawsuit against West, seeking $2.5 million. After unsuccessful negotiations between Presser and West through 2016, Judge Lewis A. Kaplan of the US Southern District of New York rejected the rapper's attempt to dismiss the suit and to transfer the case out in December. Just two days before West was slated to be deposed in the case, he reached an out-of-court deal with Presser on March 20, 2017. Details of the deal are not disclosed. Release and promotion. "New Slaves" was released on June 18, 2013, as the fourth track on West's sixth studio album "Yeezus". Prior to the song's release, it was played at 66 locations whilst a black-and-white video of West performing it was projected on various buildings in various countries around the world, including at Wrigley Field and the Royal Ontario Museum. Miriam Coleman said the simplicity of the video "provided a striking context for the rapper's searing lyrics on race and materialism". Two projections in Texas (including the Rothko Chapel) were dismissed by police prior to commencing due to a lack of permit. Another projection at Miami Beach, Florida was shut down by police, but left fans excited and eager to see the song's then-upcoming performance on "Saturday Night Live". West performed "New Slaves", along with "Black Skinhead", on "Saturday Night Live" on May 18, 2013. During the performance, West stood in place and stared dead-eyed at the camera the whole time, performing "in front of a projection of eyes." West also changed his lyrics to more TV-friendly, changing words such as "dick" to "prick." West subsequently performed the song live at the Governors Ball Music Festival on June 9, 2013. During the performance, West "paused and breathed audibly between scant verses, allowing interludes of emptiness to add to the corrosive aura." Critical reception. "New Slaves" has received widespread acclaim from music critics, with its message, sample, and Ocean's appearance receiving praise. Farber of the "Daily News" said the song has a "heavy metal girth that still swings" and called the sampling of "Gyöngyhajú lány" by Omega "the most cool, and obscure, sample" on "Yeezus". Robert Christgau of "MSN Music" cited "New Slaves", along with "Hold My Liquor", as the album's highlights. Michael Madden of "Consequence of Sound" writes: "'New Slaves' has one of the clearer concepts on the whole album, about the relationship West sees between blacks of different classes and consumerism," calling upon the lyrics: "You see it's broke-nigga racism, that's that Don't touch anything in the store'/ And this rich-nigga racism, that's that Come in, please buy more." Madden ultimately called "New Slaves" one of the album's "essential tracks," along with "Black Skinhead", "Blood on the Leaves", and "Bound 2". Evan Rytlewski of "The A.V. Club" called the song "menacing" and praised its coda with Frank Ocean. West himself has voiced his love for the song, tweeting that the second verse is the best rap verse of all time in July 2013, and reiterating his opinion in a 2014 interview with "GQ" magazine. Accolades. On June 26, 2013, "Time" named "New Slaves" the "Best Song of 2013 (So Far)" and later on December 20, 2013, placed it first on its "The 25 Best Songs of 2013 (The Entire Year)." On December 2, 2013, "Complex" named "New Slaves" the best song of 2013. Dave Bry commented saying, "Plenty of artists sold more records than Kanye West in 2013. No one did anything near to as artistically powerful. "New Slaves" is the best song of the year. And it's not even close." "NME" ranked the song at number 36 on their list of the 50 best songs of 2013. It was named the second best song of 2013 by "Pitchfork". They elaborated saying, ""New Slaves" is the hardened cartilage of Yeezus, the leanest and grisliest piece of music on an album without a single yielding surface. There isn't a wasted breath or unnecessary word; every single thought cleaves through the meat. [...] Yes, Kanye is a wealthy man, and yes, the particulars of his rage might be convoluted, involving his lack of access to the upper reaches of the fashion industry. But its source comes from an acute, unwavering awareness of a central fact: Even in the elite corridors of power where he now walks, some doors are still locked. On "New Slaves", he transforms into the hordes demanding entry. To paraphrase the words of his one-time mentor: The whole industry could hate him; he'll flail his way through." The song earned a Grammy nomination for Best Rap Song at the 56th Annual Grammy Awards, ultimately losing to "Thrift Shop" by Macklemore &amp; Ryan Lewis featuring Wanz. Live performances. Before its release on the album, West performed "New Slaves", along with "Black Skinhead", on "Saturday Night Live" on May 18, 2013. The performance introduced audiences to West's new creative shift for "Yeezus" and showed how musically different the album would be from his previous, "My Beautiful Dark Twisted Fantasy" (2010). West performed the song again at the Governors Ball Music Festival on June 9, 2013, nine days before the release of the album. Following the release of "Yeezus", West performed the song live at the first concert of The Yeezus Tour at the Barclays Center in New York City. West wore a jeweled mask during the show, which Jim Farber of New York Daily News believed contributed to "the industrial fusion he has injected on "Yeezus"." When commenting on his performance of "New Slaves" and "Black Skinhead", Farber writes: "West delivers [them] with the brutality they deserve." In September 2013, West performed an acoustic rendition of the song with Charlie Wilson on "Later... with Jools Holland". Credits and personnel. Credits adapted from the "Yeezus" liner notes.
wikipedia
{"added":"2023-04-02T20:40:41.324Z","created":"2023-04-02T20:40:41.324Z","id":"39417623","metadata":{"length":1695,"provenance":"en_simple_wiki_v0-0001.json.gz:1828402","revid":"1129221455","url":"https:\/\/en.wikipedia.org\/wiki?curid=39417623"},"source":"wikipedia","version":"v0"}
1,894
flan-13213741
Question: Based on the sentence "Wet brown dog, jumping out of the water.", is the sentence "The dog is wet from jumping in the water." true? OPTIONS: - yes - it is not possible to tell - no Answer: yes Is the premise "A woman in black holds her mouth walking down the street with a young boy." true if "The woman is walking down the street with a young girl."? OPTIONS: - yes - it is not possible to tell - no no Q: "The band is practicing before the championship game." Does this mean that "The solo band is practicing before the championship game."? OPTIONS: - yes - it is not possible to tell - no A: it is not possible to tell Premise & Hypothesis & Options: A man wearing a blue casual shirt with money green shorts and black hat pointing toward the yellow object in an elderly gathering. A man is trying to show others what a banana looks like OPTIONS: - yes - it is not possible to tell - no Is the hypothesis true or not: it is not possible to tell Premise & hypothesis: Is the premise "A woman is laying on the beach next to her bike." true if "A woman is laying on a towel."? OPTIONS: - yes - it is not possible to tell - no A: it is not possible to tell Premise & hypothesis: Is the premise "Two men in belt harnesses are working on a construction project, though only one wears his hard hat." true if "One man is acting in an unsafe manner"? OPTIONS: - yes - it is not possible to tell - no A: it is not possible to tell
flan
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380
dclm-429596050
h a l f b a k e r y It's not a thing. It will be a thing. account: browse anonymously, or get an account and write. ]~[ Rotary Engine (+2, -2)   [vote for, I thought of this engine after seeing the Radmax TM ROTARY ENGINE (see link). This idea is kind of hard to explain verbally, but I’ll try. There’s also a picture thingy I made that shows the combustion cycle. The basic idea of the engine is two cams facing towards each other with a combustion space and a rotor in between them, and a mechanical output shaft through the center. The rotor can slide along the shaft, but it only rotates with the shaft. The rotor divides the combustion space into four separate sections (two on each side). There are two full combustion cycles of the engine per revolution. The engine could be made to have multiple combustion chambers and rotors, or the rotor and chamber could be made with a larger diameter to have twice as many combustion cycles (four), which would make it have a slower rotation speed but more power and torque output. One problem I can think of is vibration of the engine; the vibration can be reduced by making the engine flatter. BJS, Feb 16 2007 Radmax TM ROTARY ENGINE http://www.regtech....otaryprinciple.html [BJS, Feb 16 2007] Rotary Engine Concept picture thingy http://www.putfile....pic.php?img=4782119 Imagine this image around a cylinder. [BJS, Feb 16 2007]        So this is just a bigger version of the Radmax engine or what? discontinuuity, Feb 16 2007        No, it's not bigger version of the Radmax engine. BJS, Feb 16 2007        interesting, but is it an improvement?           the rotor bobbing up and down while also rotating seems to add complexity (and vibration as you mention) without benefits. xaviergisz, Feb 16 2007        I don't know if it would be an improvement, it's just an idea.           Sealing it might also be a problem. BJS, Feb 16 2007        I don't see how compression could be formed. Explanation? nomel, Feb 16 2007        "I don't see how compression could be formed. Explanation?" Did you see the picture? BJS, Feb 16 2007        I had no trouble with the link to the picture. It's clever, but yeah, how are you going to seal it. baconbrain, Feb 16 2007        I saw the picture but it appears that when it rotates, the seal will be lost between "chambers"/section. You have "compression" marked, but, from what I can see, if anything moved from where it is, the seal would be lost. What forms the seal? Just contact between the metal? If this is the case, where will lubrication take place?           I'm just having trouble seeing the concept. Maybe you could animate it? nomel, Feb 17 2007        I don't know how to seal it...           I could make an animation of it, but I have other things I'm supposed to be doing right now. BJS, Feb 17 2007        hrmmm...well if you don't have a seal, then it's not going to make any power. fishy for you. nomel, Feb 18 2007        This sounds an awful lot like the Rand Cam Klaatu, Feb 18 2007        Looking at the Rotary Engine Concept picture thingy, I think this engine is brilliant. It's like a rotary version of the Scuderi engine but without any valves.           My feeling is that there might be a way to wrap that image around a circle the other way, turning it into a toothed gear. Eliminate either the top or bottom half of the mechanism, and you end up with a toothed gear rotating within a toothed stator; the stator has intake/exhaust holes as well as the transfer gaps.           By rotating it around a circle, the wobbling motion is turned into natural circular motion, and manufacturing becomes infinitely simpler. IJK, Mar 24 2007 back: main index
dclm
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958
pes2o-19171226
Merging and Outsourcing Information Systems with UML Businesses can change their business structure by merging with other companies or, on the other end of the spectrum, by smoothly outsourcing some of their business processes to other more specialized parties. In this paper, we will concentrate on conceptual modelling of merging and outsourcing information systems. Merging of a collection of information systems will be defined as the construction of a global information system that contains exactly the functionality of the original collection of systems. Such global information systems are called federated information systems, when we wish to address the situation where the component systems are so-called legacy systems; that is, systems that are given beforehand and that are to interoperate in an integrated single framework in which the legacy systems are to maintain as much as possible their respective autonomy. Two major problems in constructing federated information systems concern achieving and maintaining consistency, and a uniform representation of the data on the global level of the federation. The process of creation of uniform representations of data is known as data extraction, whereas data reconciliation is concerned with resolving data inconsistencies. Outsourcing of an information system, on the other hand, will be defined as the handing over of part of the functionality of the original system to an outside party (the supplier). Such functionality typically involves one or more operations, where each operation satisfies certain input and output requirements. These requirements will be defined in terms of the ruling service level agreements (SLAs). We will provide a formal means to ensure that the outsourcing relationship between outsourcing party and supplier, determined by an SLA, satisfies specific correctness criteria. Formal specifications, as offered in this paper, can prove their value in the setup and evaluation of outsourcing contracts. We shall describe a uniform semantic framework for specification of both federated and outsourced information systems based on the UML/OCL data model. In particular, we will show that we can represent so-called exact views in UML/OCL, providing
pes2o
{"added":"2016-01-07T01:57:53.067Z","created":"2006-01-01T00:00:00.000Z","id":"1650516","metadata":{"abstract":"Businesses can change their business structure by merging with other companies or, on the other end of the spectrum, by smoothly outsourcing some of their business processes to other more specialized parties. In this paper, we will concentrate on conceptual modelling of merging and outsourcing information systems. Merging of a collection of information systems will be defined as the construction of a global information system that contains exactly the functionality of the original collection of systems. Such global information systems are called federated information systems, when we wish to address the situation where the component systems are so-called legacy systems; that is, systems that are given beforehand and that are to interoperate in an integrated single framework in which the legacy systems are to maintain as much as possible their respective autonomy. Two major problems in constructing federated information systems concern achieving and maintaining consistency, and a uniform representation of the data on the global level of the federation. The process of creation of uniform representations of data is known as data extraction, whereas data reconciliation is concerned with resolving data inconsistencies. Outsourcing of an information system, on the other hand, will be defined as the handing over of part of the functionality of the original system to an outside party (the supplier). Such functionality typically involves one or more operations, where each operation satisfies certain input and output requirements. These requirements will be defined in terms of the ruling service level agreements (SLAs). We will provide a formal means to ensure that the outsourcing relationship between outsourcing party and supplier, determined by an SLA, satisfies specific correctness criteria. Formal specifications, as offered in this paper, can prove their value in the setup and evaluation of outsourcing contracts. We shall describe a uniform semantic framework for specification of both federated and outsourced information systems based on the UML\/OCL data model. In particular, we will show that we can represent so-called exact views in UML\/OCL, providing","abstract_count":325,"abstract_language":"en","abstract_perplexity":-12.66603274846659,"extfieldsofstudy":["Business"],"provenance":"pes2o_v2-0004.json.gz:3684619","s2fieldsofstudy":["Computer Science"],"sha1":"c5e90978ad0130cdaf85500268a96dfbd2ae7a66","sources":["Unpaywall","Grobid","ScienceParseMerged","Crawler","MAG"],"title":"Merging and Outsourcing Information Systems with UML","title_count":7,"title_language":"en","title_perplexity":-12.131033010983458,"top_frequencies":[{"count":20,"token":"of"},{"count":19,"token":"the"},{"count":9,"token":"and"},{"count":8,"token":"information"},{"count":7,"token":"systems"},{"count":7,"token":"in"},{"count":6,"token":"to"},{"count":6,"token":"will"},{"count":6,"token":"as"},{"count":6,"token":"that"},{"count":6,"token":"data"},{"count":5,"token":"on"},{"count":5,"token":"outsourcing"},{"count":5,"token":"a"},{"count":5,"token":"are"},{"count":4,"token":"their"},{"count":4,"token":"other"},{"count":4,"token":"we"},{"count":4,"token":"an"},{"count":3,"token":"with"},{"count":3,"token":"can"},{"count":3,"token":"by"},{"count":3,"token":"be"},{"count":3,"token":"defined"},{"count":3,"token":"global"},{"count":3,"token":"functionality"},{"count":3,"token":"federated"},{"count":3,"token":"uniform"},{"count":2,"token":"Merging"},{"count":2,"token":"Outsourcing"},{"count":2,"token":"business"},{"count":2,"token":"merging"},{"count":2,"token":"more"},{"count":2,"token":"In"},{"count":2,"token":"this"},{"count":2,"token":"paper,"},{"count":2,"token":"systems."},{"count":2,"token":"collection"},{"count":2,"token":"system"},{"count":2,"token":"original"},{"count":2,"token":"Such"},{"count":2,"token":"where"},{"count":2,"token":"so-called"},{"count":2,"token":"legacy"},{"count":2,"token":"framework"},{"count":2,"token":"level"},{"count":2,"token":"is"},{"count":2,"token":"party"},{"count":2,"token":"satisfies"},{"count":2,"token":"We"},{"count":1,"token":"Information"},{"count":1,"token":"Systems"},{"count":1,"token":"UML"},{"count":1,"token":"Businesses"},{"count":1,"token":"change"},{"count":1,"token":"structure"},{"count":1,"token":"companies"},{"count":1,"token":"or,"},{"count":1,"token":"end"},{"count":1,"token":"spectrum,"},{"count":1,"token":"smoothly"},{"count":1,"token":"some"},{"count":1,"token":"processes"},{"count":1,"token":"specialized"},{"count":1,"token":"parties."},{"count":1,"token":"concentrate"},{"count":1,"token":"conceptual"},{"count":1,"token":"modelling"},{"count":1,"token":"construction"},{"count":1,"token":"contains"},{"count":1,"token":"exactly"},{"count":1,"token":"called"},{"count":1,"token":"systems,"},{"count":1,"token":"when"},{"count":1,"token":"wish"},{"count":1,"token":"address"},{"count":1,"token":"situation"},{"count":1,"token":"component"},{"count":1,"token":"systems;"},{"count":1,"token":"is,"},{"count":1,"token":"given"},{"count":1,"token":"beforehand"},{"count":1,"token":"interoperate"},{"count":1,"token":"integrated"},{"count":1,"token":"single"},{"count":1,"token":"which"},{"count":1,"token":"maintain"},{"count":1,"token":"much"},{"count":1,"token":"possible"},{"count":1,"token":"respective"},{"count":1,"token":"autonomy."},{"count":1,"token":"Two"},{"count":1,"token":"major"},{"count":1,"token":"problems"},{"count":1,"token":"constructing"},{"count":1,"token":"concern"},{"count":1,"token":"achieving"},{"count":1,"token":"maintaining"},{"count":1,"token":"consistency,"},{"count":1,"token":"representation"}],"year":2006},"source":"s2","version":"v3-fos"}
402
pes2o-23246949
Valuing Japan-based German expatriate and local manager's functions: do subsidiary age and managerial perspectives matter? Managerial functions valued by expatriates and reasons for appointing host country managers were examined in an exploratory, multimethod (interview and questionnaire) study with expatriates and local managers as the respondents. Based on theoretical perspectives of agency theory, transaction costs theory, resource-based views and organizational learning theory, changes in the valuation of these functions were hypothesized and examined for subsidiary age and nationality of the respondent. Expatriate and local managers' views supported previous research on certain management functions but differed on others (e.g. management development). The data indicated curvilinear relationships for a number of managerial functions between nationality of top manager and age of the subsidiary. Strategic factors were analysed by subsidiary age and nationality of the respondent manager to understand more about maturity of host company operations and strategic orientations. The results indicated the growth in the strategic functions of technological leadership and market development/branding in older subsidiaries. Implications of the results were discussed.
pes2o
{"added":"2019-05-16T13:04:12.356Z","created":"2011-02-01T00:00:00.000Z","id":"154492137","metadata":{"abstract":"Managerial functions valued by expatriates and reasons for appointing host country managers were examined in an exploratory, multimethod (interview and questionnaire) study with expatriates and local managers as the respondents. Based on theoretical perspectives of agency theory, transaction costs theory, resource-based views and organizational learning theory, changes in the valuation of these functions were hypothesized and examined for subsidiary age and nationality of the respondent. Expatriate and local managers' views supported previous research on certain management functions but differed on others (e.g. management development). The data indicated curvilinear relationships for a number of managerial functions between nationality of top manager and age of the subsidiary. Strategic factors were analysed by subsidiary age and nationality of the respondent manager to understand more about maturity of host company operations and strategic orientations. The results indicated the growth in the strategic functions of technological leadership and market development\/branding in older subsidiaries. Implications of the results were discussed.","abstract_count":154,"abstract_language":"en","abstract_perplexity":-13.531312361492164,"extfieldsofstudy":["Business"],"provenance":"pes2o_v2-0006.json.gz:32141","s2fieldsofstudy":["Business"],"sha1":"3c0036f5647c99105a0b01cfe575ae4e45dbb854","sources":["Unpaywall","TaylorAndFrancis","MAG"],"title":"Valuing Japan-based German expatriate and local manager's functions: do subsidiary age and managerial perspectives matter?","title_count":15,"title_language":"en","title_perplexity":-16.44977378469846,"top_frequencies":[{"count":13,"token":"and"},{"count":10,"token":"of"},{"count":8,"token":"the"},{"count":5,"token":"functions"},{"count":4,"token":"age"},{"count":4,"token":"were"},{"count":4,"token":"in"},{"count":3,"token":"local"},{"count":3,"token":"subsidiary"},{"count":3,"token":"for"},{"count":3,"token":"on"},{"count":3,"token":"theory,"},{"count":3,"token":"nationality"},{"count":2,"token":"managerial"},{"count":2,"token":"perspectives"},{"count":2,"token":"by"},{"count":2,"token":"expatriates"},{"count":2,"token":"host"},{"count":2,"token":"managers"},{"count":2,"token":"examined"},{"count":2,"token":"views"},{"count":2,"token":"management"},{"count":2,"token":"The"},{"count":2,"token":"indicated"},{"count":2,"token":"manager"},{"count":2,"token":"strategic"},{"count":2,"token":"results"},{"count":1,"token":"Valuing"},{"count":1,"token":"Japan-based"},{"count":1,"token":"German"},{"count":1,"token":"expatriate"},{"count":1,"token":"manager's"},{"count":1,"token":"functions:"},{"count":1,"token":"do"},{"count":1,"token":"matter?"},{"count":1,"token":"Managerial"},{"count":1,"token":"valued"},{"count":1,"token":"reasons"},{"count":1,"token":"appointing"},{"count":1,"token":"country"},{"count":1,"token":"an"},{"count":1,"token":"exploratory,"},{"count":1,"token":"multimethod"},{"count":1,"token":"(interview"},{"count":1,"token":"questionnaire)"},{"count":1,"token":"study"},{"count":1,"token":"with"},{"count":1,"token":"as"},{"count":1,"token":"respondents."},{"count":1,"token":"Based"},{"count":1,"token":"theoretical"},{"count":1,"token":"agency"},{"count":1,"token":"transaction"},{"count":1,"token":"costs"},{"count":1,"token":"resource-based"},{"count":1,"token":"organizational"},{"count":1,"token":"learning"},{"count":1,"token":"changes"},{"count":1,"token":"valuation"},{"count":1,"token":"these"},{"count":1,"token":"hypothesized"},{"count":1,"token":"respondent."},{"count":1,"token":"Expatriate"},{"count":1,"token":"managers'"},{"count":1,"token":"supported"},{"count":1,"token":"previous"},{"count":1,"token":"research"},{"count":1,"token":"certain"},{"count":1,"token":"but"},{"count":1,"token":"differed"},{"count":1,"token":"others"},{"count":1,"token":"(e.g."},{"count":1,"token":"development)."},{"count":1,"token":"data"},{"count":1,"token":"curvilinear"},{"count":1,"token":"relationships"},{"count":1,"token":"a"},{"count":1,"token":"number"},{"count":1,"token":"between"},{"count":1,"token":"top"},{"count":1,"token":"subsidiary."},{"count":1,"token":"Strategic"},{"count":1,"token":"factors"},{"count":1,"token":"analysed"},{"count":1,"token":"respondent"},{"count":1,"token":"to"},{"count":1,"token":"understand"},{"count":1,"token":"more"},{"count":1,"token":"about"},{"count":1,"token":"maturity"},{"count":1,"token":"company"},{"count":1,"token":"operations"},{"count":1,"token":"orientations."},{"count":1,"token":"growth"},{"count":1,"token":"technological"},{"count":1,"token":"leadership"},{"count":1,"token":"market"},{"count":1,"token":"development\/branding"},{"count":1,"token":"older"},{"count":1,"token":"subsidiaries."}],"year":2011},"source":"s2","version":"v3-fos"}
214
dclm-428104914
Burger King® 15971 US RT 33 Nelsonville, OH 45764 (740) 753-4374 About Burger King® There's a BURGER KING® restaurant near you at 15971 US RT 33. Visit us or call for more information. Every day, more than 11 million guests visit over 13,000 BURGER KING® restaurants near them in 97 countries around the world. And they do so because our fast food restaurants are known for serving high-quality, great-tasting and affordable food. The BURGER KING® restaurant in Nelsonville, OH serves burgers, breakfast, lunch and dinner prepared your way. The original HOME OF THE WHOPPER®, our commitment to quality ingredients, signature recipes, iconic sandwiches like the flame-grilled WHOPPER® Sandwich and fast, family-friendly dining experiences in a welcoming environment is what has defined our brand for more than 50 successful years. Nearby Locations
dclm
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202
flan-9859389
question: COMING INTO FORCE: --> French. answer: ENTRÉE EN VIGUEUR : question: Any decision as to the termination of vendor's contract or any subcontractor shall be made by the buyer, at the sole discretion of the buyer. --> French. answer: Toute décision de résilier le contrat du fournisseur ou d’un sous-traitant sera prise par l’acheteur, à son entière discrétion. question: The then applicants furthermore considered it established that there had been a misuse of powers and an infringement of Article 39 of the EC Treaty (now Article 33 EC). --> French. answer: Les requérantes considéraient en outre comme établis les vices de détournement de pouvoir et de violation de l'article 39 du traité CE (devenu article 33 CE). question: Although, as I point out in my report, it would, technically speaking, be perfectly possible to continue to accept new Member States, even if the Treaty of Lisbon were not to enter into force, doing so requires political will, and it is this that it is my job and that of my fellow Members here in Parliament to create. --> French. answer: Bien que, comme je le souligne dans mon rapport, il serait, d'un point de vue technique, tout à fait possible d'accepter de nouveaux États membres, même si le traité de Lisbonne devait ne pas entrer en vigueur, il faut pour cela une volonté politique, et c'est mon travail, ainsi que celui de mes camarades députés, réunis ici au Parlement, de créer cette volonté.
flan
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378
flan-12664378
IN: French: The amending formula was also the subject of study by a special joint committee of the Senate and the House of Commons in 1991. OUT: La formule de modification a également été examinée en 1991 par un comité mixte spécial du Sénat et de la Chambre des communes. IN: French: Labour legislation defines a range of leaves (maternity, paternity, adoption, parental and others), which are subsidized by the public social security system in order to promote the sharing of responsibilities and the reconciling of work and family life. OUT: La législation du travail comporte toute une série de congés (maternité, paternité, adoption, parental ou autres) subventionnés par le système de sécurité sociale publique afin de promouvoir le partage des responsabilités et la conciliation de la vie professionnelle et familiale. IN: French: b) Relations between the EU and Croatia Amid increasing tension within the Socialist Federal Republic of Yugoslavia, Croatia declared independence on 25 June 1991. This was suspended for three months and confirmed on 8 October 1991 (by Parliament’s decision on the abrogation of the state-legal ties with the former SFRY). OUT: sources d’information, notamment des États membres, des organisations internationales (Conseil de l'Europe, OSCE, HCR, TPIY, Pacte de stabilité, FMI, Banque mondiale, BERD, BEI etc.) et des ONG. b) Relations entre l'Union européenne et la Croatie Dans un climat de tension croissante au sein de la république fédérative socialiste de Yougoslavie, la Croatie a déclaré son indépendance le 25 juin 1991. IN: French: In a case in which the Inter-American Commission on Human Rights found a violation of articles 25 and 8 of ACHR (the rights to effective judicial protection and to a fair trial, respectively) because the petitioner had been denied access to contentious administrative proceedings to challenge his dismissal, it recommended that the State party permit the petitioner “access to contentious administrative proceedings, in order that he might appeal the legality of the administrative act that mandated his dismissal”. OUT: Dans un cas où elle a conclu à la violation des articles 8 et 25 de la Convention américaine relative aux droits de l'homme (les droits à une protection judiciaire effective et à un jugement équitable, respectivement) parce que le requérant n'avait pas eu la possibilité d'introduire un recours administratif pour contester son licenciement, la Commission interaméricaine des droits de l'homme a recommandé à l'État partie d'autoriser le requérant « à introduire un recours administratif pour contester la légalité de l'acte administratif signifiant son licenciement ».
flan
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669
flan-8578419
Question: What is the solution? Solve -25*f = -67*f - 82*f - 13*f + 4521 for f. Answer: 33 Question: What is the solution? Solve 202*b + 386 - 4199 = -581 for b. Answer: 16 Question: What is the solution? Solve 439 - 4057 = 208*y + 3*y + 391 for y. Answer: -19 Question: What is the solution? Solve 0 = -3*x + 11 - 5 for x. Answer: 2
flan
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135
flan-25032022
How is "In Kuwait, work in the diplomatic and consular corps is restricted to men alone, with the one exception of the woman at the head of the Kuwaiti diplomatic mission in Vienna, who was formerly a member of the Permanent Mission of Kuwait in New York, following which she was appointed as Kuwait's ambassador to South Africa." said in French? La nomination dans les corps diplomatique et consulaire koweïtiens est limitée aux hommes, à l'exception notable de la chef de la mission diplomatique du Koweït à Vienne, qui était auparavant membre de la Mission permanente du Koweït à New York puis a été nommée ambassadrice du Koweït en Afrique du Sud.
flan
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160
dclm-411648434
The Global Vegan Cosmetics Market is expected to grow from USD 13,100.38 Million in 2019 to USD 19,373.16 Million by the end of 2025 at a Compound Annual Growth Rate (CAGR) of 6.73%. Market Segmentation & Coverage: This research report categorizes the Vegan Cosmetics to forecast the revenues and analyze the trends in each of the following sub-markets: Based on Product, the Vegan Cosmetics Market studied across Hair Care, Makeup, and Skin Care. Based on Distribution Channel, the Vegan Cosmetics Market studied across Departmental Stores, E-commerce, Hypermarket/Supermarket, and Specialty Stores. Company Usability Profiles: The report deeply explores the recent significant developments by the leading vendors and innovation profiles in the Global Vegan Cosmetics Market including Bare Blossom Skincare & Organics, Billy Jealousy, Debenhams Plc, e.l.f. Beauty Inc., Ecco Bella, L’Or?al SA, Lush Fresh Handmade Cosmetics, Modern Minerals Makeup, MuLondon Natural Skincare, and Urban Decay. FPNV Positioning Matrix: The FPNV Positioning Matrix evaluates and categorizes the vendors in the Vegan Cosmetics Market on the basis of Business Strategy (Business Growth, Industry Coverage, Financial Viability, and Channel Support) and Product Satisfaction (Value for Money, Ease of Use, Product Features, and Customer Support) that aids businesses in better decision making and understanding the competitive landscape. Competitive Strategic Window: Cumulative Impact of COVID-19: The report provides insights on the following pointers: The report answers questions such as: 1. What is the market size and forecast of the Global Vegan Cosmetics Market? 2. What are the inhibiting factors and impact of COVID-19 shaping the Global Vegan Cosmetics Market during the forecast period? 3. Which are the products/segments/applications/areas to invest in over the forecast period in the Global Vegan Cosmetics Market? 4. What is the competitive strategic window for opportunities in the Global Vegan Cosmetics Market? 5. What are the technology trends and regulatory frameworks in the Global Vegan Cosmetics Market? 6. What are the modes and strategic moves considered suitable for entering the Global Vegan Cosmetics Market?
dclm
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512
dclm-417700635
Desperate Housewives Season 1 "One Wonderful Day" Bree and Rex make amends, but then tragedy hits the Van De Kamp family. Zach learns what happened to his father. Edie meets the new residents of Wisteria Lane. "Goodbye For Now" Susan and Mike move in together. Lynette tries to make sure Annabel (Melinda McGraw) doesn't come between her and Tom, but ends up getting Tom fired. "Sunday in the Park with George" George continues to weasel his way into Bree's Life. Rex's health continues to detoriate. Lynette tries to spice things up with Tom. "Fear No More" Gabrielle plans a farewell party for Carlos before he leaves for jail for eight months. George Williams (Roger Bart) resurfaces in Bree's life. "Live Alone and Like It" Lynette learns that no good deed goes unpunished when she befriends Mrs. McCluskey. Susan's mother tries to jump start her and her daughter's love lives and ends up picking him up a man. "Children Will Listen" "There Won't Be Trumpets" "The Ladies Who Lunch" Mike is questioned about Mrs. Huber's murder by the police and is temporarily arrested. John's friend, Justin (Ryan Carnes) attempts to blackmail Gabrielle into making him her new gardener. "Love is in the Air" When Lynette's father-in-aw, Rodney Scavo (Ryan O'Neal), comes to visit, she learns that he's been cheating on his wife. Susan is disturbed by Julie's romance with Zach. "Every Day a Little Death" The residents of Wisteria Lane learn that Martha Huber has passed away and they discover she kept a journal, forcing Susan to confess to Edie about her role in burning the house down. Edie organizes a neighborhood search for the missing Mrs. Huber, just as her sister, Felicia Tilman (Harriet Sansom Harris) arrives. Bree asks an attractive pharmacist on a date. "Come Back to Me" Maisy Gibbons (Sharon Lawrence) returns and her secret life intersects with Bree's. Gabrielle gets a taste of her own medicine when Carlos confesses in jail. Susan plans to take her relationship with Mike to the next level. "Suspicious Minds" Gabrielle organizes a Halston fashion show for charity highlighting the ladies of Wisteria Lane. John's mother, Helen Rowlan (Kathryn Harrold) thinks her son is sleeping with Susan and not Gabrielle, but Gabrielle soon confesses. The aftermath of Bree's son Andrew running over Carlos' mother. Susan grows suspicious of Mike's intentions of moving to Wisteria Lane. Lynette reaches the breaking point in her addiction to ADD medication. "Anything You Can Do" Susan and Mike's first official date is postponed when a sexy house guest, Kendra (Heather Stephens), comes to visit Mike. Lynette becomes more dependent on her kids' ADD medication. "Running to Stand Still" Lynette butts heads with Maisy Gibbons (Sharon Lawrence) at the twins' school over a play. Susan investigates the mystery of Zach's sudden disappearance. "Come In, Stranger" A break-in on Wisteria Lane makes a vulnerable Susan accept a date with a policeman when Mike seems indifferent. Rex takes the kids for the weekend, leaving a lonely Bree behind. "Who's That Woman?" Cash-strapped Mrs. Huber blackmails Susan about being involved with Edie's housefire. Carlos becomes suspicious that Gabrielle is having an affair and accuses the wrong man. "Pretty Little Picture" The ladies host the big dinner party that the late Mary Alice Young had planned; Gabrielle finds herself being blackmailed by a nine-year-old who catches her with ther gardener "Ah, But Underneath" Edie crashes Mike's dinner date with Susan; Gabrielle realizes her gardener is taking their fling too seriously; Bree forces Rex to go to therapy; Lynette resorts to drastic measures to keep her kids in line. Mary Alice Young commits suicide one day in her house. She narrates the story of her family, friends and neighbors from her point of view. Desperate Housewives Air Dates: Total Episodes: Desperate Housewives Season 1 Quotes Mary Alice Lynette: Now listen to me, you are going to behave. I will not be humiliated in front of the entire neighborhood. And just so you know that I'm serious, I am. (She pulls out paper) Porter: What's that? Lynette: Santa's cell phone number! Preston: How'd you get that? Lynette: I know someone who knows someone who knows an elf. And if any of you acts up, so help me I will call Santa and tell him you want socks for Christmas! All right, are you willing to risk that!?
dclm
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1,133
pes2o-24037526
Vein wrapping for chronic nerve constriction injury in a rat model: study showing increases in VEGF and HGF production and prevention of pain-associated behaviors and nerve damage. BACKGROUND Although efficacious clinical results have been reported after vein wrapping for the treatment of recurrent compressive neuropathy, the mechanism of nerve protection remains uncertain. METHODS Eight-week-old male Wistar rats (n = 90) were randomly divided into three groups: sham procedure, chronic constriction injury, and chronic constriction injury plus vein wrapping. Mechanical withdrawal thresholds and walking patterns were measured with use of von Frey filaments and the CatWalk system, respectively. We investigated L4-L5 dorsal root ganglia immunohistochemically at fourteen days postsurgery and sciatic nerves histologically at fourteen days and again five months postsurgery. Concentrations of several sciatic neurotrophic factors in the ligated sciatic nerves were quantified with use of ELISA (enzyme-linked immunosorbent assay). RESULTS In behavioral tests, the rats in which the chronic constriction injury had been followed by vein wrapping displayed significantly greater pain responses than the sham group, and the group with untreated chronic constriction injury showed greater pain responses than the vein-wrapping group (both p < 0.05). Immunoreactive markers of inflammation and nerve damage, calcitonin gene-related peptide (CGRP) and activating transcription factor-3 (ATF3), were upregulated in dorsal root ganglion neurons in the constriction-injury and vein-wrapping groups compared with those in the sham group, with greater upregulation in the constriction-injury group than in the vein-wrapping group (both p < 0.01). Histologic observation showed marked nerve degeneration and scar tissue formation around the sciatic nerve in the constriction-injury group, but these effects were prevented to some extent in the vein-wrapping group. Vascular endothelial growth factor (VEGF) levels at one and three days postsurgery and hepatocyte growth factor (HGF) levels at three, seven, fourteen, and twenty-eight days postsurgery were significantly higher in the vein-wrapping group than in the other groups (p < 0.05). CONCLUSIONS Vein wrapping decreased pain-associated behavior and nerve damage caused by chronic constriction injury. VEGF and HGF produced in response to vein grafts may play a mechanistic role. CLINICAL RELEVANCE These findings may lead to development of new therapies employing growth factors, with or without other materials, that simulate vein wrapping.
pes2o
{"added":"2018-04-03T01:20:59.490Z","created":"2014-05-21T00:00:00.000Z","id":"22958957","metadata":{"abstract":"BACKGROUND\nAlthough efficacious clinical results have been reported after vein wrapping for the treatment of recurrent compressive neuropathy, the mechanism of nerve protection remains uncertain.\n\n\nMETHODS\nEight-week-old male Wistar rats (n = 90) were randomly divided into three groups: sham procedure, chronic constriction injury, and chronic constriction injury plus vein wrapping. Mechanical withdrawal thresholds and walking patterns were measured with use of von Frey filaments and the CatWalk system, respectively. We investigated L4-L5 dorsal root ganglia immunohistochemically at fourteen days postsurgery and sciatic nerves histologically at fourteen days and again five months postsurgery. Concentrations of several sciatic neurotrophic factors in the ligated sciatic nerves were quantified with use of ELISA (enzyme-linked immunosorbent assay).\n\n\nRESULTS\nIn behavioral tests, the rats in which the chronic constriction injury had been followed by vein wrapping displayed significantly greater pain responses than the sham group, and the group with untreated chronic constriction injury showed greater pain responses than the vein-wrapping group (both p < 0.05). Immunoreactive markers of inflammation and nerve damage, calcitonin gene-related peptide (CGRP) and activating transcription factor-3 (ATF3), were upregulated in dorsal root ganglion neurons in the constriction-injury and vein-wrapping groups compared with those in the sham group, with greater upregulation in the constriction-injury group than in the vein-wrapping group (both p < 0.01). Histologic observation showed marked nerve degeneration and scar tissue formation around the sciatic nerve in the constriction-injury group, but these effects were prevented to some extent in the vein-wrapping group. Vascular endothelial growth factor (VEGF) levels at one and three days postsurgery and hepatocyte growth factor (HGF) levels at three, seven, fourteen, and twenty-eight days postsurgery were significantly higher in the vein-wrapping group than in the other groups (p < 0.05).\n\n\nCONCLUSIONS\nVein wrapping decreased pain-associated behavior and nerve damage caused by chronic constriction injury. VEGF and HGF produced in response to vein grafts may play a mechanistic role.\n\n\nCLINICAL RELEVANCE\nThese findings may lead to development of new therapies employing growth factors, with or without other materials, that simulate vein wrapping.","abstract_count":334,"abstract_language":"en","abstract_perplexity":-16.241104700295732,"extfieldsofstudy":["Medicine"],"provenance":"pes2o_v2-0006.json.gz:822718","s2fieldsofstudy":["Biology","Medicine"],"sha1":"a0bc8e27f691ebe4af6c22cf127929e968220e45","sources":["MergedPDFExtraction","Medline","Unpaywall","MAG"],"title":"Vein wrapping for chronic nerve constriction injury in a rat model: study showing increases in VEGF and HGF production and prevention of pain-associated behaviors and nerve damage.","title_count":27,"title_language":"en","title_perplexity":-14.49384208516575,"top_frequencies":[{"count":18,"token":"and"},{"count":18,"token":"the"},{"count":14,"token":"in"},{"count":8,"token":"of"},{"count":7,"token":"nerve"},{"count":6,"token":"chronic"},{"count":6,"token":"constriction"},{"count":6,"token":"were"},{"count":6,"token":"with"},{"count":5,"token":"vein"},{"count":5,"token":"group"},{"count":5,"token":"vein-wrapping"},{"count":4,"token":"wrapping"},{"count":4,"token":"injury"},{"count":4,"token":"at"},{"count":4,"token":"days"},{"count":4,"token":"sciatic"},{"count":4,"token":"than"},{"count":3,"token":"sham"},{"count":3,"token":"postsurgery"},{"count":3,"token":"greater"},{"count":3,"token":"group,"},{"count":3,"token":"<"},{"count":3,"token":"constriction-injury"},{"count":3,"token":"to"},{"count":3,"token":"growth"},{"count":2,"token":"Vein"},{"count":2,"token":"for"},{"count":2,"token":"a"},{"count":2,"token":"VEGF"},{"count":2,"token":"HGF"},{"count":2,"token":"pain-associated"},{"count":2,"token":"been"},{"count":2,"token":"rats"},{"count":2,"token":"three"},{"count":2,"token":"wrapping."},{"count":2,"token":"use"},{"count":2,"token":"dorsal"},{"count":2,"token":"root"},{"count":2,"token":"fourteen"},{"count":2,"token":"nerves"},{"count":2,"token":"by"},{"count":2,"token":"significantly"},{"count":2,"token":"pain"},{"count":2,"token":"responses"},{"count":2,"token":"showed"},{"count":2,"token":"(both"},{"count":2,"token":"p"},{"count":2,"token":"0.05)."},{"count":2,"token":"groups"},{"count":2,"token":"factor"},{"count":2,"token":"levels"},{"count":2,"token":"other"},{"count":2,"token":"may"},{"count":1,"token":"rat"},{"count":1,"token":"model:"},{"count":1,"token":"study"},{"count":1,"token":"showing"},{"count":1,"token":"increases"},{"count":1,"token":"production"},{"count":1,"token":"prevention"},{"count":1,"token":"behaviors"},{"count":1,"token":"damage."},{"count":1,"token":"BACKGROUND"},{"count":1,"token":"Although"},{"count":1,"token":"efficacious"},{"count":1,"token":"clinical"},{"count":1,"token":"results"},{"count":1,"token":"have"},{"count":1,"token":"reported"},{"count":1,"token":"after"},{"count":1,"token":"treatment"},{"count":1,"token":"recurrent"},{"count":1,"token":"compressive"},{"count":1,"token":"neuropathy,"},{"count":1,"token":"mechanism"},{"count":1,"token":"protection"},{"count":1,"token":"remains"},{"count":1,"token":"uncertain."},{"count":1,"token":"METHODS"},{"count":1,"token":"Eight-week-old"},{"count":1,"token":"male"},{"count":1,"token":"Wistar"},{"count":1,"token":"(n"},{"count":1,"token":"="},{"count":1,"token":"90)"},{"count":1,"token":"randomly"},{"count":1,"token":"divided"},{"count":1,"token":"into"},{"count":1,"token":"groups:"},{"count":1,"token":"procedure,"},{"count":1,"token":"injury,"},{"count":1,"token":"plus"},{"count":1,"token":"Mechanical"},{"count":1,"token":"withdrawal"},{"count":1,"token":"thresholds"},{"count":1,"token":"walking"},{"count":1,"token":"patterns"},{"count":1,"token":"measured"},{"count":1,"token":"von"}],"year":2014},"source":"s2","version":"v3-fos"}
530
pes2o-15104363
Impact of Wind Power and Photovoltaic Cell Power on Power System Stability Based on L Index L index is proposed to assess the impact of wind power and photovoltaic cell power on system stability. L index is a voltage stability index which is based on power flow and can reflect the weak point where wind power and photovoltaic cell are connected to. Because the day trends of the two DGs are different, the impacts of stability are different. The example shows wind power system could cause voltage stability fluctuation. And the photovoltaic cell could enhance stability in strong light and high temperature in daytime.
pes2o
{"added":"2017-02-24T19:11:08.977Z","created":"2012-03-27T00:00:00.000Z","id":"44541064","metadata":{"abstract":"L index is proposed to assess the impact of wind power and photovoltaic cell power on system stability. L index is a voltage stability index which is based on power flow and can reflect the weak point where wind power and photovoltaic cell are connected to. Because the day trends of the two DGs are different, the impacts of stability are different. The example shows wind power system could cause voltage stability fluctuation. And the photovoltaic cell could enhance stability in strong light and high temperature in daytime.","abstract_count":88,"abstract_language":"en","abstract_perplexity":-12.140337017771705,"extfieldsofstudy":["Environmental Science"],"provenance":"pes2o_v2-0003.json.gz:3489173","s2fieldsofstudy":["Engineering","Environmental Science"],"sha1":"121fad97e3b26870d3710741fbb93c506448579a","sources":["ScienceParseMerged","MAG","Unpaywall","IEEE"],"title":"Impact of Wind Power and Photovoltaic Cell Power on Power System Stability Based on L Index","title_count":16,"title_language":"en","title_perplexity":-11.121987890026766,"top_frequencies":[{"count":6,"token":"the"},{"count":5,"token":"and"},{"count":5,"token":"power"},{"count":4,"token":"of"},{"count":4,"token":"on"},{"count":4,"token":"stability"},{"count":3,"token":"Power"},{"count":3,"token":"L"},{"count":3,"token":"index"},{"count":3,"token":"is"},{"count":3,"token":"wind"},{"count":3,"token":"photovoltaic"},{"count":3,"token":"cell"},{"count":3,"token":"are"},{"count":2,"token":"system"},{"count":2,"token":"voltage"},{"count":2,"token":"could"},{"count":2,"token":"in"},{"count":1,"token":"Impact"},{"count":1,"token":"Wind"},{"count":1,"token":"Photovoltaic"},{"count":1,"token":"Cell"},{"count":1,"token":"System"},{"count":1,"token":"Stability"},{"count":1,"token":"Based"},{"count":1,"token":"Index"},{"count":1,"token":"proposed"},{"count":1,"token":"to"},{"count":1,"token":"assess"},{"count":1,"token":"impact"},{"count":1,"token":"stability."},{"count":1,"token":"a"},{"count":1,"token":"which"},{"count":1,"token":"based"},{"count":1,"token":"flow"},{"count":1,"token":"can"},{"count":1,"token":"reflect"},{"count":1,"token":"weak"},{"count":1,"token":"point"},{"count":1,"token":"where"},{"count":1,"token":"connected"},{"count":1,"token":"to."},{"count":1,"token":"Because"},{"count":1,"token":"day"},{"count":1,"token":"trends"},{"count":1,"token":"two"},{"count":1,"token":"DGs"},{"count":1,"token":"different,"},{"count":1,"token":"impacts"},{"count":1,"token":"different."},{"count":1,"token":"The"},{"count":1,"token":"example"},{"count":1,"token":"shows"},{"count":1,"token":"cause"},{"count":1,"token":"fluctuation."},{"count":1,"token":"And"},{"count":1,"token":"enhance"},{"count":1,"token":"strong"},{"count":1,"token":"light"},{"count":1,"token":"high"},{"count":1,"token":"temperature"},{"count":1,"token":"daytime."}],"year":2012},"source":"s2","version":"v3-fos"}
127
pes2o-11019276
Technology extraction from time series data reflecting expert operator skills and knowledge Continuation processes in chemical and/or biotechnical plants always generate a large amount of time series data. However, since conventional process models are described as a set of control models, it is difficult to explain the complicated and active plant behaviours. Based on the background, this paper proposes a novel method to develop a process response model from continuous time-series data. The method consists of the following phases: (1) reciprocal correlation analysis, (2) process response model, (3) extraction of control rules, (4) extraction of a workflow and (5) detecting outliers. The main contribution of the research is to establish a method to mine a set of meaningful control rules from Learning Classifier System (LCS) using the Minimum Description Length (MDL) criteria and Tabu search method. The proposed method has been applied to an actual process of a biochemical plant and has shown the validity and the effectiveness.
pes2o
{"added":"2018-01-23T22:42:11.579Z","created":"2008-12-31T00:00:00.000Z","id":"41086273","metadata":{"abstract":"Continuation processes in chemical and\/or biotechnical plants always generate a large amount of time series data. However, since conventional process models are described as a set of control models, it is difficult to explain the complicated and active plant behaviours. Based on the background, this paper proposes a novel method to develop a process response model from continuous time-series data. The method consists of the following phases: (1) reciprocal correlation analysis, (2) process response model, (3) extraction of control rules, (4) extraction of a workflow and (5) detecting outliers. The main contribution of the research is to establish a method to mine a set of meaningful control rules from Learning Classifier System (LCS) using the Minimum Description Length (MDL) criteria and Tabu search method. The proposed method has been applied to an actual process of a biochemical plant and has shown the validity and the effectiveness.","abstract_count":146,"abstract_language":"en","abstract_perplexity":-14.622418492212738,"extfieldsofstudy":["Engineering","Computer Science"],"provenance":"pes2o_v2-0002.json.gz:3280075","s2fieldsofstudy":["Computer Science"],"sha1":"6c6cdc504704f56557d31bcb42592182736c82b0","sources":["DBLP","MAG","Unpaywall"],"title":"Technology extraction from time series data reflecting expert operator skills and knowledge","title_count":12,"title_language":"en","title_perplexity":-11.999942198241254,"top_frequencies":[{"count":8,"token":"a"},{"count":8,"token":"of"},{"count":7,"token":"the"},{"count":6,"token":"and"},{"count":5,"token":"to"},{"count":4,"token":"process"},{"count":4,"token":"method"},{"count":3,"token":"extraction"},{"count":3,"token":"from"},{"count":3,"token":"control"},{"count":3,"token":"The"},{"count":2,"token":"time"},{"count":2,"token":"series"},{"count":2,"token":"data."},{"count":2,"token":"set"},{"count":2,"token":"is"},{"count":2,"token":"plant"},{"count":2,"token":"response"},{"count":2,"token":"has"},{"count":1,"token":"Technology"},{"count":1,"token":"data"},{"count":1,"token":"reflecting"},{"count":1,"token":"expert"},{"count":1,"token":"operator"},{"count":1,"token":"skills"},{"count":1,"token":"knowledge"},{"count":1,"token":"Continuation"},{"count":1,"token":"processes"},{"count":1,"token":"in"},{"count":1,"token":"chemical"},{"count":1,"token":"and\/or"},{"count":1,"token":"biotechnical"},{"count":1,"token":"plants"},{"count":1,"token":"always"},{"count":1,"token":"generate"},{"count":1,"token":"large"},{"count":1,"token":"amount"},{"count":1,"token":"However,"},{"count":1,"token":"since"},{"count":1,"token":"conventional"},{"count":1,"token":"models"},{"count":1,"token":"are"},{"count":1,"token":"described"},{"count":1,"token":"as"},{"count":1,"token":"models,"},{"count":1,"token":"it"},{"count":1,"token":"difficult"},{"count":1,"token":"explain"},{"count":1,"token":"complicated"},{"count":1,"token":"active"},{"count":1,"token":"behaviours."},{"count":1,"token":"Based"},{"count":1,"token":"on"},{"count":1,"token":"background,"},{"count":1,"token":"this"},{"count":1,"token":"paper"},{"count":1,"token":"proposes"},{"count":1,"token":"novel"},{"count":1,"token":"develop"},{"count":1,"token":"model"},{"count":1,"token":"continuous"},{"count":1,"token":"time-series"},{"count":1,"token":"consists"},{"count":1,"token":"following"},{"count":1,"token":"phases:"},{"count":1,"token":"(1)"},{"count":1,"token":"reciprocal"},{"count":1,"token":"correlation"},{"count":1,"token":"analysis,"},{"count":1,"token":"(2)"},{"count":1,"token":"model,"},{"count":1,"token":"(3)"},{"count":1,"token":"rules,"},{"count":1,"token":"(4)"},{"count":1,"token":"workflow"},{"count":1,"token":"(5)"},{"count":1,"token":"detecting"},{"count":1,"token":"outliers."},{"count":1,"token":"main"},{"count":1,"token":"contribution"},{"count":1,"token":"research"},{"count":1,"token":"establish"},{"count":1,"token":"mine"},{"count":1,"token":"meaningful"},{"count":1,"token":"rules"},{"count":1,"token":"Learning"},{"count":1,"token":"Classifier"},{"count":1,"token":"System"},{"count":1,"token":"(LCS)"},{"count":1,"token":"using"},{"count":1,"token":"Minimum"},{"count":1,"token":"Description"},{"count":1,"token":"Length"},{"count":1,"token":"(MDL)"},{"count":1,"token":"criteria"},{"count":1,"token":"Tabu"},{"count":1,"token":"search"},{"count":1,"token":"method."},{"count":1,"token":"proposed"},{"count":1,"token":"been"}],"year":2008},"source":"s2","version":"v3-fos"}
200
wikipedia-5831131
Benjamin M. Washburn Benjamin Martin Washburn (June 1, 1887 – October 16, 1966) was an American prelate who served as the fifth bishop of Newark in The Episcopal Church. Early life and education. Washburn was born on June 1, 1887, in Bethel, Vermont, United States. Son of Seth Monroe Washburn and Kate Strong Brooks. He studied at and graduated with a Bachelor of Arts in 1907. Later he studied at the General Theological Seminary and graduated with a Bachelor of Divinity in 1913. He was awarded a Doctor of Divinity from Dartmouth College in 1929, Kenyon College in 1949 and Hobart College in 1951. In 1933 he was awarded a Doctor of Sacred Theology from General Theological Seminary. Ordained ministry. He was ordained deacon on June, 1912 in St Paul's Church in Burlington, Vermont, and a priest on May 18, 1913, both by Arthur C. A. Hall of Vermont. He served as curate of Grace Church in New York City from 1912 to 1915 after which he became vicar. In 1918 he became rector of St Paul's Church in Kansas City, Kansas. Between 1929 and 1932 he was the rector of Emmanuel Church in Boston. Bishop. Washburn was elected Coadjutor Bishop of Newark in 1932 and was consecrated on October 14, 1932, by Presiding Bishop James De Wolf Perry. In 1935 he succeeded as diocesan bishop where he remained till 1958. He died after a long illness on October 16, 1966, in Ridgefield, Connecticut.
wikipedia
{"added":"2023-04-02T20:40:41.324Z","created":"2023-04-02T20:40:41.324Z","id":"46652008","metadata":{"length":284,"provenance":"en_simple_wiki_v0-0001.json.gz:2610930","revid":"753665","url":"https:\/\/en.wikipedia.org\/wiki?curid=46652008"},"source":"wikipedia","version":"v0"}
332
flan-13954681
Saudis Bankroll Taliban, Even as King Officially Supports Afghan Government In interviews with The New York Times, a former Taliban finance minister described how he traveled to Saudi Arabia for years raising money while ostensibly on pilgrimage. The Taliban have also been allowed to raise additional millions by extorting “taxes” by pressing hundreds of thousands of Pashtun guest workers in the kingdom and menacing their families back home, according to Vali Nasr, a former State Department adviser. Yet even as private Saudi money backed the Taliban, Saudi intelligence once covertly mediated a peace effort that Taliban officials and others involved described in full to The Times for the first time. Playing multiple sides of the same geopolitical equation is one way the Saudis further their own strategic interests, analysts and officials say. But it also threatens to undermine the fragile democratic advances made by the United States during the past 15 years, and potentially undo efforts to liberalize the country. The United States now finds itself trying to persuade its putative ally to play a constructive rather than destructive role. Meanwhile, the Afghans have come to view Saudi Arabia as both friend and foe. The question now, as Afghan officials look for help, is which Saudi Arabia will they get? Prince Turki al-Faisal, who led the Saudi intelligence agency for over 24 years and later served as ambassador to the United States until his retirement in 2007, rejected any suggestion that Saudi Arabia had ever supported the Taliban. “When I was in government, not a single penny went to the Taliban,” he wrote in emailed comments. He added that the “stringent measures taken by the kingdom to prevent any transfer of money to terrorist groups” had been recognized by Daniel L. Glaser, the United States assistant secretary for terrorist financing at the Treasury, in testimony to Congress in June. Others say the verdict is still out. “We know there has been this financing that has gone on for years,” Hanif Atmar, director of the Afghan National Security Council, said in an interview. “This sustains the terrorist war machine in Afghanistan and in the region, and it will have to be stopped.” That may be easier said than done. Saudi Arabia remains one of the main sources of what Secretary of State John Kerry recently called “surrogate money” to support Islamist fighters and causes. Much of that largess is spread about in pursuit of what Mr. Nasr describes as a Saudi strategy of building a wall of Sunni radicalism across South and Central Asia to contain Iran, its Shia rival. That competition is being rekindled. With the Americans leaving, there is the sense that Afghanistan’s fate is up for grabs. In recent months, the Taliban has mounted a coordinated offensive with about 40,000 fighters across eight provinces — a push financed by foreign sources at a cost of $1 billion, according to Afghan officials. At the same time, Saudi Arabia is offering the Afghan government substantial defense and development agreements, while Afghans say sheikhs from Saudi Arabia and other Arab Persian Gulf states are quietly funneling billions in private money to Sunni social organizations, madrasas and universities to shape the next generation of Afghans. “The Saudis are re-engaging,” said Mr. Nasr, now dean of the Johns Hopkins School of Advanced International Studies, in a telephone interview. “Afghanistan is important to them, which is why they invested so much in the 1980s, and they are looking to make themselves much more relevant.” The seven-year Taliban theocracy in Afghanistan was coming to a fiery end. It was 2001, and the Taliban government was collapsing under the United States bombing campaign unleashed in retaliation for the Sept. 11 attacks. Disguising himself as a doctor, Agha Jan Motasim, the Taliban finance minister, escaped over a remote border crossing into Pakistan aboard a Red Crescent ambulance, he said in a recent interview. In the Pakistani border town of Quetta, he and other Taliban leaders regrouped and began organizing the insurgency that continues today. Mr. Motasim was appointed head of the finance committee and set about collecting funds. One of his first stops was Saudi Arabia. As home to both enormous oil wealth and Islam’s holiest sites, it was the perfect place to make appeals not only to rich Saudi sheikhs and foundations but also to important donors who traveled to the kingdom on pilgrimage from all over the Muslim world. Between 2002 and 2007, Mr. Motasim traveled to Saudi Arabia two or three times a year. Ostensibly he went on pilgrimage, but his primary purpose was to raise cash for the Taliban. “There were people coming from other countries for umrah and hajj,” he said referring to the different Muslim pilgrimages. “Also the Saudi sheikhs would come as well. I would ask them for their help for the war.” “It was not only the Saudis who would help us but people who would come from different countries,” he recalled. “Saudi Arabia was the only country where I could meet them.” Once secured, the money could be moved in myriad ways to Taliban coffers, officials in the region said, including through regional banks close to Pakistan’s tribal areas and the hawala system of informal money-changers. Last year, Afghan security forces even discovered families of members of Al Qaeda entering eastern Afghanistan with a stash of gold bars, according to Rahmatullah Nabil, the former head of Afghanistan’s intelligence agency, the National Directorate of Security. The Saudi authorities often say they cannot control or always identify the millions of Muslims who travel to the kingdom every year on the hajj, said Barnett Rubin, who worked as special adviser to the United States envoy for Afghanistan and Pakistan. The Taliban always traveled on fake Pakistani passports under assumed names and were unknown to Saudi authorities, according to a security official in the region, who spoke on condition of strict anonymity, citing the extreme sensitivity to upsetting Saudi Arabia. American requests to cut the funding yielded little result. In 2009, American officials complained that the Taliban and other extremist groups were raising millions of dollars during annual pilgrimages, according to American diplomatic cables released by WikiLeaks. A December 2009 cable from Secretary of State Hillary Clinton stated that donors in Saudi Arabia constituted the “most significant source of funding to Sunni terrorist groups worldwide.” The cables date from a period when Richard C. Holbrooke, who died in 2010, acted as special envoy for Afghanistan and Pakistan, and actively sought to curb funding to the Taliban, if in vain. The funding from the gulf extended well beyond that period and to other groups besides the Taliban, including the Islamic State, also known as ISIS or ISIL. In a leaked email from 2014, Mrs. Clinton described the governments of Qatar and Saudi Arabia as “providing clandestine financial and logistic support to ISIL and other radical Sunni groups in the region.” Financing such groups, she wrote, was part of a contest between Qatar and Saudi Arabia, who were in “ongoing competition to dominate the Sunni world.” summary: Saudi Arabia has voiced support for American efforts to nourish Afghanistan’s democracy, but it has also lavishly funded Sunni extremism under various guises. Winter heating bills to be higher this year With winter temperatures expected to return to normal following last year’s mild season, Massachusetts residents who warm their homes with oil can expect to spend a record amount in the next six months, according to a forecast released by the federal government Wednesday. The combination of high prices — averaging $3.80 a gallon this season — and colder weather will drive fuel bills for heating oil consumers to around $2,500, on average, this winter, according to the US Energy Information Administration. That’s more than any previous winter on record, and roughly $400 more than consumers spent last season. But many Massachusetts residents … This is an article preview. The full story is available to BostonGlobe.com subscribers. summary: With winter temperatures expected to return to normal following last year’s mild season, Massachusetts residents who warm their homes with heating oil can expect spend a record amount in the next six months, according to a federal forecast released Wednesday.
flan
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1,758
flan-17176473
Question: Solve 1339*q = 1352*q + 52 for q.. Answer: -4 Question: Solve 120*g - 123*g + 12 = 0 for g.. Answer: 4 Question: Solve -36*z - 48 = -147 + 63 for z.. Answer: 1 Question: Solve 298*i = -233 + 363 + 2552 for i.. Answer: 9
flan
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103
stackexchange-1983692
Mutable variable is accessible from closure I have the following code: for (var i = 0; i < data.length; i++) { var file = data[i]; $.getJSON("/types/" + file, function(json) { if (json[0] !== undefined) { console.log(json[0] + file); } }); } But my editor is saying "Mutable variable is accessible from closure". I've tried to change function(json) { to function(json, file) {, but this don't work because this is a default function of jquery. I hope you can help my fixing the problem. For such loops, you need to put the contents in a closure. for (var i = 0; i < data.length; i++) { (function(){ var file = data[i]; $.getJSON("/types/" + file, function(json) { if (json[0] !== undefined) { console.log(json[0] + file); } }); })(); }
stackexchange
{"added":"2014-09-03T07:46:47.950","attributes":{"dedupe_para_ngrams_13_1":[[74.0,114.0,1.0],[622.0,662.0,1.0],[707.0,760.0,1.0]]},"created":"2014-09-03T07:39:58.663","id":"stackoverflow_com-25638834-25638959","metadata":{"answer_comment_count":3,"answer_content_license":"CC BY-SA 3.0","answer_id":25638959,"answer_last_activity_date":"2014-09-03T07:46:47.950","answer_last_edit_date":"","answer_last_editor_user_id":0,"answer_owner_user_id":461872,"answer_score":19,"answer_view_count":0,"forum":"stackoverflow_com","provenance":"20241028_173636_00007_mgema_c48018f0-45d2-49fe-911b-ce2fc79312a8.zst:420769","question_comment_count":2,"question_content_license":"CC BY-SA 3.0","question_id":25638834,"question_last_activity_date":"2015-12-10T07:00:10.073","question_last_edit_date":"2014-09-03T07:40:32.683","question_last_editor_user_id":2256771,"question_owner_user_id":3967022,"question_score":4,"question_view_count":10762},"source":"stackexchange","version":"20240930"}
252
pes2o-21122229
Two-dimensional thin-layer chromatography fingerprint profiles of ten Cirsium species by chemometric processing Ten methanolic extracts of selected Cirsium species were analyzed using two-dimensional thin-layer chromatography (2D-TLC) system with octadecyl reversed-phase (RP-18) chromatographic plate as the stationary phase and two eluents: nonaqueous, consisting of 2-butanone-toluene-acetic acid (4.5:5:0.5, v/v) used in the first direction of developing, and aqueous, consisting of methanol—water—formic acid (4:5:1, v/v) used in the second direction. The Naturstoff reagent was used for the derivatization of some phenolic compounds. Five selected standards were analyzed under the same chromatographic conditions, and their retention factor values were used for the confirmation of their presence on selected Cirsium chromatograms. Photographs of ten chromatograms were treated using the ImageJ program. 2D-TLC analysis was also performed to obtain the fingerprint chromatographic profiles of the studied methanolic extracts. The experimental data were objected to principal component analysis (PCA), and the PC2 vs. PC3 graphs were created. Based on the PCA results, the similarity between the selected Cirsium species was confirmed.
pes2o
{"added":"2019-04-08T13:08:55.013Z","created":"2016-11-15T00:00:00.000Z","id":"100003236","metadata":{"abstract":"Ten methanolic extracts of selected Cirsium species were analyzed using two-dimensional thin-layer chromatography (2D-TLC) system with octadecyl reversed-phase (RP-18) chromatographic plate as the stationary phase and two eluents: nonaqueous, consisting of 2-butanone-toluene-acetic acid (4.5:5:0.5, v\/v) used in the first direction of developing, and aqueous, consisting of methanol\u2014water\u2014formic acid (4:5:1, v\/v) used in the second direction. The Naturstoff reagent was used for the derivatization of some phenolic compounds. Five selected standards were analyzed under the same chromatographic conditions, and their retention factor values were used for the confirmation of their presence on selected Cirsium chromatograms. Photographs of ten chromatograms were treated using the ImageJ program. 2D-TLC analysis was also performed to obtain the fingerprint chromatographic profiles of the studied methanolic extracts. The experimental data were objected to principal component analysis (PCA), and the PC2 vs. PC3 graphs were created. Based on the PCA results, the similarity between the selected Cirsium species was confirmed.","abstract_count":152,"abstract_language":"en","abstract_perplexity":-17.418351739384192,"extfieldsofstudy":["Chemistry"],"provenance":"pes2o_v2-0005.json.gz:1759494","s2fieldsofstudy":["Chemistry"],"sha1":"70a382a4c339fd1f3765bac1b2714b1e44532ff2","sources":["MAG","Unpaywall","Springer","MergedPDFExtraction"],"title":"Two-dimensional thin-layer chromatography fingerprint profiles of ten Cirsium species by chemometric processing","title_count":12,"title_language":"en","title_perplexity":-17.032646931912907,"top_frequencies":[{"count":13,"token":"the"},{"count":9,"token":"of"},{"count":6,"token":"were"},{"count":4,"token":"Cirsium"},{"count":4,"token":"selected"},{"count":4,"token":"and"},{"count":4,"token":"used"},{"count":3,"token":"species"},{"count":3,"token":"chromatographic"},{"count":3,"token":"was"},{"count":2,"token":"thin-layer"},{"count":2,"token":"chromatography"},{"count":2,"token":"fingerprint"},{"count":2,"token":"profiles"},{"count":2,"token":"ten"},{"count":2,"token":"methanolic"},{"count":2,"token":"analyzed"},{"count":2,"token":"using"},{"count":2,"token":"consisting"},{"count":2,"token":"acid"},{"count":2,"token":"v\/v)"},{"count":2,"token":"in"},{"count":2,"token":"The"},{"count":2,"token":"for"},{"count":2,"token":"their"},{"count":2,"token":"on"},{"count":2,"token":"analysis"},{"count":2,"token":"to"},{"count":1,"token":"Two-dimensional"},{"count":1,"token":"by"},{"count":1,"token":"chemometric"},{"count":1,"token":"processing"},{"count":1,"token":"Ten"},{"count":1,"token":"extracts"},{"count":1,"token":"two-dimensional"},{"count":1,"token":"(2D-TLC)"},{"count":1,"token":"system"},{"count":1,"token":"with"},{"count":1,"token":"octadecyl"},{"count":1,"token":"reversed-phase"},{"count":1,"token":"(RP-18)"},{"count":1,"token":"plate"},{"count":1,"token":"as"},{"count":1,"token":"stationary"},{"count":1,"token":"phase"},{"count":1,"token":"two"},{"count":1,"token":"eluents:"},{"count":1,"token":"nonaqueous,"},{"count":1,"token":"2-butanone-toluene-acetic"},{"count":1,"token":"(4.5:5:0.5,"},{"count":1,"token":"first"},{"count":1,"token":"direction"},{"count":1,"token":"developing,"},{"count":1,"token":"aqueous,"},{"count":1,"token":"methanol\u2014water\u2014formic"},{"count":1,"token":"(4:5:1,"},{"count":1,"token":"second"},{"count":1,"token":"direction."},{"count":1,"token":"Naturstoff"},{"count":1,"token":"reagent"},{"count":1,"token":"derivatization"},{"count":1,"token":"some"},{"count":1,"token":"phenolic"},{"count":1,"token":"compounds."},{"count":1,"token":"Five"},{"count":1,"token":"standards"},{"count":1,"token":"under"},{"count":1,"token":"same"},{"count":1,"token":"conditions,"},{"count":1,"token":"retention"},{"count":1,"token":"factor"},{"count":1,"token":"values"},{"count":1,"token":"confirmation"},{"count":1,"token":"presence"},{"count":1,"token":"chromatograms."},{"count":1,"token":"Photographs"},{"count":1,"token":"chromatograms"},{"count":1,"token":"treated"},{"count":1,"token":"ImageJ"},{"count":1,"token":"program."},{"count":1,"token":"2D-TLC"},{"count":1,"token":"also"},{"count":1,"token":"performed"},{"count":1,"token":"obtain"},{"count":1,"token":"studied"},{"count":1,"token":"extracts."},{"count":1,"token":"experimental"},{"count":1,"token":"data"},{"count":1,"token":"objected"},{"count":1,"token":"principal"},{"count":1,"token":"component"},{"count":1,"token":"(PCA),"},{"count":1,"token":"PC2"},{"count":1,"token":"vs."},{"count":1,"token":"PC3"},{"count":1,"token":"graphs"},{"count":1,"token":"created."},{"count":1,"token":"Based"},{"count":1,"token":"PCA"},{"count":1,"token":"results,"}],"year":2016},"source":"s2","version":"v3-fos"}
275
pes2o-22209900
Vibegron for the treatment of overactive bladder: a comprehensive update ABSTRACT Introduction Overactive bladder (OAB) is associated with physical, emotional, and financial burden. After failed conservative measures, second-line therapy includes medications, such as antimuscarinics and beta-3 adrenergic receptor (β3AR) agonists. Antimuscarinics are most commonly prescribed but have systemic side effects that lead to poor compliance. β3AR agonists include mirabegron and vibegron. Mirabegron is a first-generation β3AR agonist that is effective for frequency, urgency urinary incontinence (UUI) and urgency, but has interactions with cytochrome P450 enzymes (CYPs) and cardiovascular sequelae. Vibegron is a second-generation β3AR agonist that is highly selective and does not interact with CYPs. It is effective for reducing UUI episodes and daily micturition number and has a favorable side effect profile. Areas covered Clinical background, pharmacology, and clinical studies for vibegron. Expert opinion Vibegron is a welcomed addition to the OAB therapeutic landscape. This single dose, once daily option is effective, especially for patients with wet OAB, with a favorable side effect profile. Sub-analyses of patients ≥ 65 years have shown continued efficacy and safety. The few drug interactions are of benefit, especially for older patients with polypharmacy. As long-term data accrues, vibegron has the potential to drive the OAB therapeutic market.
pes2o
{"added":"2022-09-21T06:16:49.416Z","created":"2022-09-02T00:00:00.000Z","id":"252381737","metadata":{"abstract":"ABSTRACT Introduction Overactive bladder (OAB) is associated with physical, emotional, and financial burden. After failed conservative measures, second-line therapy includes medications, such as antimuscarinics and beta-3 adrenergic receptor (\u03b23AR) agonists. Antimuscarinics are most commonly prescribed but have systemic side effects that lead to poor compliance. \u03b23AR agonists include mirabegron and vibegron. Mirabegron is a first-generation \u03b23AR agonist that is effective for frequency, urgency urinary incontinence (UUI) and urgency, but has interactions with cytochrome P450 enzymes (CYPs) and cardiovascular sequelae. Vibegron is a second-generation \u03b23AR agonist that is highly selective and does not interact with CYPs. It is effective for reducing UUI episodes and daily micturition number and has a favorable side effect profile. Areas covered Clinical background, pharmacology, and clinical studies for vibegron. Expert opinion Vibegron is a welcomed addition to the OAB therapeutic landscape. This single dose, once daily option is effective, especially for patients with wet OAB, with a favorable side effect profile. Sub-analyses of patients \u2265 65 years have shown continued efficacy and safety. The few drug interactions are of benefit, especially for older patients with polypharmacy. As long-term data accrues, vibegron has the potential to drive the OAB therapeutic market.","abstract_count":194,"abstract_language":"en","abstract_perplexity":-16.580094998287684,"extfieldsofstudy":["Medicine"],"provenance":"pes2o_v2-0005.json.gz:2847165","s2fieldsofstudy":["Medicine"],"sha1":"88682f1b922cc85e07003b410ebe335bf60c69de","sources":["Medline","MergedPDFExtraction","Crossref","TaylorAndFrancis","ScienceParsePlus"],"title":"Vibegron for the treatment of overactive bladder: a comprehensive update","title_count":10,"title_language":"en","title_perplexity":-14.576165835542088,"top_frequencies":[{"count":10,"token":"and"},{"count":8,"token":"is"},{"count":6,"token":"for"},{"count":6,"token":"a"},{"count":6,"token":"with"},{"count":4,"token":"the"},{"count":3,"token":"Vibegron"},{"count":3,"token":"of"},{"count":3,"token":"side"},{"count":3,"token":"that"},{"count":3,"token":"to"},{"count":3,"token":"\u03b23AR"},{"count":3,"token":"has"},{"count":3,"token":"patients"},{"count":2,"token":"are"},{"count":2,"token":"but"},{"count":2,"token":"have"},{"count":2,"token":"vibegron."},{"count":2,"token":"agonist"},{"count":2,"token":"effective"},{"count":2,"token":"interactions"},{"count":2,"token":"daily"},{"count":2,"token":"favorable"},{"count":2,"token":"effect"},{"count":2,"token":"profile."},{"count":2,"token":"OAB"},{"count":2,"token":"therapeutic"},{"count":2,"token":"especially"},{"count":1,"token":"treatment"},{"count":1,"token":"overactive"},{"count":1,"token":"bladder:"},{"count":1,"token":"comprehensive"},{"count":1,"token":"update"},{"count":1,"token":"ABSTRACT"},{"count":1,"token":"Introduction"},{"count":1,"token":"Overactive"},{"count":1,"token":"bladder"},{"count":1,"token":"(OAB)"},{"count":1,"token":"associated"},{"count":1,"token":"physical,"},{"count":1,"token":"emotional,"},{"count":1,"token":"financial"},{"count":1,"token":"burden."},{"count":1,"token":"After"},{"count":1,"token":"failed"},{"count":1,"token":"conservative"},{"count":1,"token":"measures,"},{"count":1,"token":"second-line"},{"count":1,"token":"therapy"},{"count":1,"token":"includes"},{"count":1,"token":"medications,"},{"count":1,"token":"such"},{"count":1,"token":"as"},{"count":1,"token":"antimuscarinics"},{"count":1,"token":"beta-3"},{"count":1,"token":"adrenergic"},{"count":1,"token":"receptor"},{"count":1,"token":"(\u03b23AR)"},{"count":1,"token":"agonists."},{"count":1,"token":"Antimuscarinics"},{"count":1,"token":"most"},{"count":1,"token":"commonly"},{"count":1,"token":"prescribed"},{"count":1,"token":"systemic"},{"count":1,"token":"effects"},{"count":1,"token":"lead"},{"count":1,"token":"poor"},{"count":1,"token":"compliance."},{"count":1,"token":"agonists"},{"count":1,"token":"include"},{"count":1,"token":"mirabegron"},{"count":1,"token":"Mirabegron"},{"count":1,"token":"first-generation"},{"count":1,"token":"frequency,"},{"count":1,"token":"urgency"},{"count":1,"token":"urinary"},{"count":1,"token":"incontinence"},{"count":1,"token":"(UUI)"},{"count":1,"token":"urgency,"},{"count":1,"token":"cytochrome"},{"count":1,"token":"P450"},{"count":1,"token":"enzymes"},{"count":1,"token":"(CYPs)"},{"count":1,"token":"cardiovascular"},{"count":1,"token":"sequelae."},{"count":1,"token":"second-generation"},{"count":1,"token":"highly"},{"count":1,"token":"selective"},{"count":1,"token":"does"},{"count":1,"token":"not"},{"count":1,"token":"interact"},{"count":1,"token":"CYPs."},{"count":1,"token":"It"},{"count":1,"token":"reducing"},{"count":1,"token":"UUI"},{"count":1,"token":"episodes"},{"count":1,"token":"micturition"},{"count":1,"token":"number"},{"count":1,"token":"Areas"},{"count":1,"token":"covered"}],"year":2022},"source":"s2","version":"v3-fos"}
313
dclm-420593708
Q Menu < Qualifications < Art and Design < Biology < Business < Chemistry < Combined Science < Computer Science < Criminology < Design and Technology < Drama (and Theatre) < Economics < Electronics < English Language < English Language and Literature < English Literature < Environmental Science < Extended Project < Film Studies < Food Preparation and Nutrition < French < Geography < Geology < German < Global Business Communication < Health and Social Care < History < Hospitality and Catering < Latin < Law < Mathematics < Media Studies < Medical Science < Music < Physical Education < Physics < Psychology < Religious Studies < Sociology < Spanish < Leadership and Management < Contact Us Unseen poetry, understanding the 'rhyme and reason' This summer, thousands of students across England will be presented with two pieces of unseen poetry and will be asked to analyse, interpret and compare these poems. As we mark World Poetry Day, we ask Julia Harrison, a subject specialist for GCSE English Literature at WJEC Eduqas, for her thoughts on this style of assessment. "This type of assessment really encourages students to get under the skin of the subject, and to apply their analytical, critical and comparative skills - rather than simply regurgitating classroom learnt interpretations. "Being assessed on unseen poetry allows students to showcase their ability to analyse language, form and structure, whilst using relevant subject terminology, and applying the skills that they have developed throughout their English studies. "We've assessed students through unseen poetry for several years and we find that students do very well in this type of assessment. What's more, teachers have found that unseen poetry focuses their teaching on developing their students' skills, giving them the tools to examine pieces of poetry in depth, skills that can then be applied in other areas of their studies." Is there a right answer? Julia has these words of advice for students sitting their examinations in the summer: "A simple, but effective rule of thumb when faced with an unseen poem is to ask yourself, 'what is it about', 'what is it REALLY about' and 'how do you know?'. There is no need to learn acronyms which incorporate lists of terminology. It is your interpretation that is important, evidenced with close reference to specific details from the text." Top Tips: As students prepare for the summer examination series, here are 4 top tips for students  when examining unseen poetry. When faced with a unseen poems, students should ask themselves the following;  1. Think about the content and structure of each poem – what are they about? How are they organised? 2. What messages or themes are the poets wanting us to think about? 3. What effect do the words, phrases and images have on us? 4. There is no 'right' answer. An interpretation of a poem is personal. Explain your responses sensibly, and give reasons for your ideas with reference to the text. For further information: Julia Harrison Subject Officer English Literature 029 2026 5374 Lisa Roberts Subject Support Officer 029 2026 5051 Matt Oatley Subject Support Officer 029 2026 5054
dclm
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701
wikipedia-1912192
Jack Hunn Sir Jack Kent Hunn (24 August 1906 – 14 June 1997) was a New Zealand civil servant. Hunn served as Secretary of Defence, Secretary of Maori Affairs, Secretary of Justice, and Chairman of the Fire Service Commission. Early life. Hunn was born in Masterton, and attended Wairarapa High School, before joining the Public Trust Office as a cadet. He attended Victoria University of Wellington, where he gained an LLM. Hunn joined the PSA in 1940, and worked on the executive, and became New Zealand Public Service Association President in 1945. In 1946, Hunn stepped down to become an Inspector of the Public Service Commission, working within Government to resolve public sector industrial issues. He became a commissioner in 1954, and expanded his knowledge across a broad range of the public service. While a commissioner, Hunn acted as secretary of Internal Affairs, Secretary of Justice, and Secretary of Maori Affairs. Hunn Report. In 1960, Prime Minister Walter Nash engaged Hunn to do a review of the Maori Affairs Department. Hunn included in his review a wide-ranging summary of Maori assets, and the state of Maori in New Zealand at the time. Maori were going through a process of urbanisation, and Hunn's report raised the issue of integration of Maori within broader New Zealand, as opposed to segregation or assimilation. The Hunn report served as the blueprint for the establishment of the Maori Education Foundation, and the New Zealand Maori Council, and became the basis for Maori policy throughout the 1960s. Secretary of Defence. Hunn was appointed to the new role of Secretary of Defence in 1963. This involved the establishment of a civilian department to be charged with defence policy, separate from the military Chiefs of Defence Staff. He advocated a full integration of the New Zealand Defence services, but was opposed by the individual military forces. During 1964 Hunn was a strong opponent of New Zealand involvement in Vietnam. Initially, New Zealand Ambassador to Washington George Laking was a strong advocate for intervention, with internal opposition from Secretary of Foreign Affairs Alister McIntosh. Hunn was the clearest opponent: while Defence Chiefs were in favour of New Zealand involvement, Hunn argued that New Zealand's interests remained with supporting Malaysia, but that South Vietnam was not a sovereign state, and did not need military support. When New Zealand sent combat forces to Vietnam in 1965, Hunn retired early from Defence. Retirement. Hunn served as Chairman of the Fire Service Commission from 1973-1977, and under the mandate of Internal Affairs Minister Allan Highet, he established a national professional fire service from a large number of small, provincial brigades. He also wrote his memoir, "Not Only Affairs of State". Personal life. Hunn's two sons have been prominent in public life: his elder son, Don Hunn, was a senior diplomat and served as State Services Commissioner, and his younger son, John, was Chief Executive and Chairman of the Todd Corporation. Honours. Hunn was appointed a Companion of the Order of St Michael and St George in the 1964 Queen's Birthday Honours. In the 1976 New Year Honours, he was made a Knight Bachelor for public services, especially as chair of the Fire Services Commission. In 1977, he was awarded the Queen Elizabeth II Silver Jubilee Medal.
wikipedia
{"added":"2023-04-02T20:40:41.324Z","created":"2023-04-02T20:40:41.324Z","id":"7925171","metadata":{"length":624,"provenance":"en_simple_wiki_v0-0000.json.gz:1912193","revid":"196446","url":"https:\/\/en.wikipedia.org\/wiki?curid=7925171"},"source":"wikipedia","version":"v0"}
699
pes2o-4472860
Perinatal hypoxic/ischemic encephalopathy: clinical challenge and experimental implications. Perinatal asphyxia is an important cause of neonatal mortality and subsequent sequelae. Striatum, richly innervated by nigrostriatal dopaminergic projections, is susceptible to perinatal insults. Measuring the cerebral cortical oxygen pressure and striatal extracellular dopamine in the striatum in piglets under different kinds and degrees of hypoxia/ischemia insult, the changes of extracellular striatal dopamine were found to be more related to the changes in blood pressure than with cortical oxygen pressure. After asphyxia, cortical oxygen pressure was significantly higher in piglets breathing 100% O2 than in those breathing 21% O2. Two hours after reoxygenation, there was a secondary release of more dopamine in piglets ventilated with 100% O2 than in those with 21% O2. Although 100% FiO2 after asphyxia increases more cortical oxygenation, it also results in poorer recovery in dopamine metabolism and higher secondary release of striatal dopamine, which may exacerbate post-hypoxic cerebral injury. Striatal lesions may strongly be related with levels of extracellular dopamine during different degrees and kinds of insults. The study of the urine 1H-NMR spectra in newborns within six hours after birth demonstrated that the lactate/creatinine ratio in newborns with subsequent hypoxic-ischemic encephalopathy was significantly higher than in those with perinatal distress only and in normal newborns. The urine lactate/creatinine ratio in newborns with perinatal distress only was also significantly higher than that in normal newborns. The levels of urinary lactate/creatinine by 1H-NMR spectroscopy within six hours after birth correlates well with subsequent hypoxic-ischemic encephalopathy. The characteristics of urine 1H-NMR spectra can be sensitively and specifically used to identify early after birth for the asphyxiated newborns with potential subsequent hypoxic-ischemic encephalopathy.
pes2o
{"added":"2018-04-03T00:31:07.768Z","created":"1998-06-30T00:00:00.000Z","id":"12713541","metadata":{"abstract":"Perinatal asphyxia is an important cause of neonatal mortality and subsequent sequelae. Striatum, richly innervated by nigrostriatal dopaminergic projections, is susceptible to perinatal insults. Measuring the cerebral cortical oxygen pressure and striatal extracellular dopamine in the striatum in piglets under different kinds and degrees of hypoxia\/ischemia insult, the changes of extracellular striatal dopamine were found to be more related to the changes in blood pressure than with cortical oxygen pressure. After asphyxia, cortical oxygen pressure was significantly higher in piglets breathing 100% O2 than in those breathing 21% O2. Two hours after reoxygenation, there was a secondary release of more dopamine in piglets ventilated with 100% O2 than in those with 21% O2. Although 100% FiO2 after asphyxia increases more cortical oxygenation, it also results in poorer recovery in dopamine metabolism and higher secondary release of striatal dopamine, which may exacerbate post-hypoxic cerebral injury. Striatal lesions may strongly be related with levels of extracellular dopamine during different degrees and kinds of insults. The study of the urine 1H-NMR spectra in newborns within six hours after birth demonstrated that the lactate\/creatinine ratio in newborns with subsequent hypoxic-ischemic encephalopathy was significantly higher than in those with perinatal distress only and in normal newborns. The urine lactate\/creatinine ratio in newborns with perinatal distress only was also significantly higher than that in normal newborns. The levels of urinary lactate\/creatinine by 1H-NMR spectroscopy within six hours after birth correlates well with subsequent hypoxic-ischemic encephalopathy. The characteristics of urine 1H-NMR spectra can be sensitively and specifically used to identify early after birth for the asphyxiated newborns with potential subsequent hypoxic-ischemic encephalopathy.","abstract_count":265,"abstract_language":"en","abstract_perplexity":-15.69102099730583,"extfieldsofstudy":["Medicine"],"provenance":"pes2o_v2-0001.json.gz:610329","s2fieldsofstudy":["Medicine","Biology"],"sha1":"61638856332ffdc3ccc70bc8653eb1183df85f74","sources":["Medline","MAG"],"title":"Perinatal hypoxic\/ischemic encephalopathy: clinical challenge and experimental implications.","title_count":8,"title_language":"en","title_perplexity":-19.50471425184599,"top_frequencies":[{"count":15,"token":"in"},{"count":10,"token":"of"},{"count":9,"token":"with"},{"count":8,"token":"and"},{"count":7,"token":"the"},{"count":5,"token":"dopamine"},{"count":5,"token":"than"},{"count":5,"token":"after"},{"count":4,"token":"subsequent"},{"count":4,"token":"to"},{"count":4,"token":"cortical"},{"count":4,"token":"was"},{"count":4,"token":"higher"},{"count":4,"token":"The"},{"count":4,"token":"newborns"},{"count":3,"token":"perinatal"},{"count":3,"token":"oxygen"},{"count":3,"token":"pressure"},{"count":3,"token":"striatal"},{"count":3,"token":"extracellular"},{"count":3,"token":"piglets"},{"count":3,"token":"be"},{"count":3,"token":"more"},{"count":3,"token":"significantly"},{"count":3,"token":"100%"},{"count":3,"token":"those"},{"count":3,"token":"hours"},{"count":3,"token":"urine"},{"count":3,"token":"1H-NMR"},{"count":3,"token":"birth"},{"count":3,"token":"lactate\/creatinine"},{"count":3,"token":"hypoxic-ischemic"},{"count":2,"token":"Perinatal"},{"count":2,"token":"asphyxia"},{"count":2,"token":"is"},{"count":2,"token":"by"},{"count":2,"token":"insults."},{"count":2,"token":"cerebral"},{"count":2,"token":"different"},{"count":2,"token":"kinds"},{"count":2,"token":"degrees"},{"count":2,"token":"changes"},{"count":2,"token":"related"},{"count":2,"token":"breathing"},{"count":2,"token":"O2"},{"count":2,"token":"21%"},{"count":2,"token":"O2."},{"count":2,"token":"secondary"},{"count":2,"token":"release"},{"count":2,"token":"also"},{"count":2,"token":"may"},{"count":2,"token":"levels"},{"count":2,"token":"spectra"},{"count":2,"token":"within"},{"count":2,"token":"six"},{"count":2,"token":"that"},{"count":2,"token":"ratio"},{"count":2,"token":"distress"},{"count":2,"token":"only"},{"count":2,"token":"normal"},{"count":2,"token":"newborns."},{"count":2,"token":"encephalopathy."},{"count":1,"token":"hypoxic\/ischemic"},{"count":1,"token":"encephalopathy:"},{"count":1,"token":"clinical"},{"count":1,"token":"challenge"},{"count":1,"token":"experimental"},{"count":1,"token":"implications."},{"count":1,"token":"an"},{"count":1,"token":"important"},{"count":1,"token":"cause"},{"count":1,"token":"neonatal"},{"count":1,"token":"mortality"},{"count":1,"token":"sequelae."},{"count":1,"token":"Striatum,"},{"count":1,"token":"richly"},{"count":1,"token":"innervated"},{"count":1,"token":"nigrostriatal"},{"count":1,"token":"dopaminergic"},{"count":1,"token":"projections,"},{"count":1,"token":"susceptible"},{"count":1,"token":"Measuring"},{"count":1,"token":"striatum"},{"count":1,"token":"under"},{"count":1,"token":"hypoxia\/ischemia"},{"count":1,"token":"insult,"},{"count":1,"token":"were"},{"count":1,"token":"found"},{"count":1,"token":"blood"},{"count":1,"token":"pressure."},{"count":1,"token":"After"},{"count":1,"token":"asphyxia,"},{"count":1,"token":"Two"},{"count":1,"token":"reoxygenation,"},{"count":1,"token":"there"},{"count":1,"token":"a"},{"count":1,"token":"ventilated"},{"count":1,"token":"Although"},{"count":1,"token":"FiO2"},{"count":1,"token":"increases"}],"year":1998},"source":"s2","version":"v3-fos"}
385
dclm-413335256
While AddressAccelerator can be run when other users are accessing the database, we recommend that users log out of before running the process on the entire database. This will improve performance and processing time. Additionally, it will prevent exceptions caused by records being in use at the time that AddressAccelerator tries to update them.
dclm
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65
flan-14612065
IN: Kanye West completes work on 'the best album of all time' Kanye West’s seventh studio album Swish is now complete. According to the rapper, “the best album of all time” is finished just in time for its 11 February release. In the runup to its unveiling, West has previewed a number of new tracks, including No More Parties in LA featuring Kendrick Lamar, Fade featuring Post Malone and Ty Dolla $ign, and Real Friends. These are featured on the handwritten tracklist – adorned with a message from Kylie Jenner – while previous singles such as All Day and Only One have been left off the forthcoming record. While the list of West’s collaborators on the follow-up to 2013’s Yeezus has not yet been revealed, alongside the aforementioned, the track Wolves, performed on Saturday Day Night Live, features Sia and Vic Mensa. News of the new album should give relief to those dismayed by the possibility that West was considering making an album of David Bowie covers and interpretations. Just 24 hours after the rumours of his possible tribute album emerged, a petition to stop him from doing so had been set up. What is a short summary of the above article? OUT: After weeks of trailing songs from the album, the rapper releases the tracklist for his seventh album Swish IN: Want a New Job? 'Show Your Work!' Says Texas Author Want a new job? "Show your work!" asserts Austin Kleon, author of a breezy but smart and confident new book with exactly that title, right down to the exclamation point. Technology and the Internet, Kleon says, offer opportunity like never before to network yourself and your talents. And it's not just for "artsy" types. "People who don't necessarily consider themselves creative now have access to tools that were only available to artists in the past," says Kleon, who will be delivering the opening keynote at the blockbuster South by Southwest Interactive conference Friday in Austin, Texas, which doubles as Kleon's hometown, "Almost everyone has a smartphone, and there are tools available that everybody can afford; two, three bucks for an app." Kleon's new book is a common-sense sequel to his 2012 best seller, "Steal Like an Artist." If the previous book was about finding your creative spark, his new one wants to help readers market themselves after the creative spark's been ignited -- another example of the D.I.Y. school of job-hunting. A brisk 215-page read, small and square, full of pictures, drawings, handwritten scrawl and other gimmicky but appealing touches, "Show Your Work!" offers a list of ten familiar but savvy guidelines to success: "Think Process, Not Product"; "Tell Good Stories"; "Teach What You Know"; "Learn to Take a Punch": "Sell Out"; "Stick Around," etc. Collaboration key The book's primary point is an extended riff on the musician Brian Eno's concept of the "Scenius," as opposed to "genius." Eno's point is that great advancements are far more often made through collaborative effort and groups than the lone genius. Eno made the assertion years ago, but Kleon writes that technology and the Internet has made the opportunity for Scenius a far broader option for workers and thinkers everywhere. "The key today is for people of all careers and all fields of work to think about how they can share what they do in a way that could be interesting and could connect them with like-minded people or customers," Kleon said in an interview with AOL Jobs. "For example, I wish there was a plumber who had 20 second clips on Instagram. Things I could look to when I had a simple project; then when I had a major job, he'd probably be the guy I call." Kleon, who is 30, said the idea came to him when he was still a copywriter at a small advertising agency in Austin. "I had one client, a grocery store where I shopped -- I was actually a customer even before we won the account. I was always trying to get them to let me in there with a flip cam, I wanted to shoot minute-long video where Bob the butcher would explain about how to pick out a ribeye, or Ed the bagger could show how to effectively bag groceries, and we could share it through social media." The author was frustrated when the grocery store balked at the idea, but "I think that's what people crave," Kleon says. "People are used to talking to each other through these networks, human beings. People like to see a human face." Kleon says that, like it or not, economic reality is moving towards an age of what the investment advisors and writers James Davidson and William Rees-Mogg have called "The Sovereign Individual": the decentralization of the workplace and democratization of talent. People can either adapt and thrive or ignore at their own expense. "Everything and everyone is so unsure now - 'Is my job even going to exist in 5-10 years?'" Kleon asks, rhetorically. "So my point is that people should build connections by showing their work. People will say, 'Oh - I follow him. He's got a great blog, or I've seen his work,' You control your own media network." It also breeds honesty and clarity; anybody can write anything about themselves on LinkedIn, for example. But actually showing a cabinet you've made, a kitchen you've refurbished, or a hairstyling you've created is hard to dispute. "This is not a method for people who cheat," Kleon jokes, laughing, but simultaneously making his point. "This is for real people doing real work that they can show in an interesting way." Austin Kleon will deliver the opening keynote for SXSW at 2pm Central time Friday, March 7, at the Austin Convention Center. What is a short summary of the above article? OUT: Courtesy Austin KleonAustin Kleon says anyone in any profe ion can show their work and should. Want a new job? "Show your work!" a erts Austin Kleon, author of a breezy but
flan
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1,322
pes2o-7078443
A study into the links between mortgage financing and economic development in Africa Purpose – The purpose of this paper is to explore the link between mortgage financing and economic development for African countries, as there is a gap in the literature regarding this topic. The development of mortgage markets is important for the overall development of a country. Policymakers and international institutions like the World Bank have been promoting the expansion of Africa’s nascent mortgage markets as a logical stimulus to economic growth and development. Specifically, the authors analyze the link between the size of the mortgage market and the gross national income (GNI) per capita for African countries. They found a significant positive correlation between the size of the mortgage market and GNI per capita. A plausible interpretation is that mortgage financing can induce growth and development. Design/methodology/approach – The authors examine the relationship between mortgage financing and GNI per capita for African countries using the hedonic framework. Findings – The authors found a s...
pes2o
{"added":"2019-05-17T14:40:52.990Z","created":"2016-02-29T00:00:00.000Z","id":"155397672","metadata":{"abstract":"Purpose \u2013 The purpose of this paper is to explore the link between mortgage financing and economic development for African countries, as there is a gap in the literature regarding this topic. The development of mortgage markets is important for the overall development of a country. Policymakers and international institutions like the World Bank have been promoting the expansion of Africa\u2019s nascent mortgage markets as a logical stimulus to economic growth and development. Specifically, the authors analyze the link between the size of the mortgage market and the gross national income (GNI) per capita for African countries. They found a significant positive correlation between the size of the mortgage market and GNI per capita. A plausible interpretation is that mortgage financing can induce growth and development. Design\/methodology\/approach \u2013 The authors examine the relationship between mortgage financing and GNI per capita for African countries using the hedonic framework. Findings \u2013 The authors found a s...","abstract_count":154,"abstract_language":"en","abstract_perplexity":-12.960636705496512,"extfieldsofstudy":["Economics"],"provenance":"pes2o_v2-0001.json.gz:3215912","s2fieldsofstudy":["Economics"],"sha1":"2a3ce99bbb6413ce9ae52fe4ecbc4095a0fc4176","sources":["Unpaywall","MAG"],"title":"A study into the links between mortgage financing and economic development in Africa","title_count":13,"title_language":"en","title_perplexity":-10.043255096302,"top_frequencies":[{"count":15,"token":"the"},{"count":8,"token":"mortgage"},{"count":8,"token":"and"},{"count":6,"token":"of"},{"count":5,"token":"between"},{"count":5,"token":"a"},{"count":4,"token":"financing"},{"count":4,"token":"development"},{"count":4,"token":"The"},{"count":4,"token":"is"},{"count":4,"token":"for"},{"count":3,"token":"economic"},{"count":3,"token":"\u2013"},{"count":3,"token":"African"},{"count":3,"token":"authors"},{"count":3,"token":"per"},{"count":2,"token":"A"},{"count":2,"token":"in"},{"count":2,"token":"this"},{"count":2,"token":"to"},{"count":2,"token":"link"},{"count":2,"token":"as"},{"count":2,"token":"markets"},{"count":2,"token":"growth"},{"count":2,"token":"development."},{"count":2,"token":"size"},{"count":2,"token":"market"},{"count":2,"token":"capita"},{"count":2,"token":"found"},{"count":2,"token":"GNI"},{"count":1,"token":"study"},{"count":1,"token":"into"},{"count":1,"token":"links"},{"count":1,"token":"Africa"},{"count":1,"token":"Purpose"},{"count":1,"token":"purpose"},{"count":1,"token":"paper"},{"count":1,"token":"explore"},{"count":1,"token":"countries,"},{"count":1,"token":"there"},{"count":1,"token":"gap"},{"count":1,"token":"literature"},{"count":1,"token":"regarding"},{"count":1,"token":"topic."},{"count":1,"token":"important"},{"count":1,"token":"overall"},{"count":1,"token":"country."},{"count":1,"token":"Policymakers"},{"count":1,"token":"international"},{"count":1,"token":"institutions"},{"count":1,"token":"like"},{"count":1,"token":"World"},{"count":1,"token":"Bank"},{"count":1,"token":"have"},{"count":1,"token":"been"},{"count":1,"token":"promoting"},{"count":1,"token":"expansion"},{"count":1,"token":"Africa\u2019s"},{"count":1,"token":"nascent"},{"count":1,"token":"logical"},{"count":1,"token":"stimulus"},{"count":1,"token":"Specifically,"},{"count":1,"token":"analyze"},{"count":1,"token":"gross"},{"count":1,"token":"national"},{"count":1,"token":"income"},{"count":1,"token":"(GNI)"},{"count":1,"token":"countries."},{"count":1,"token":"They"},{"count":1,"token":"significant"},{"count":1,"token":"positive"},{"count":1,"token":"correlation"},{"count":1,"token":"capita."},{"count":1,"token":"plausible"},{"count":1,"token":"interpretation"},{"count":1,"token":"that"},{"count":1,"token":"can"},{"count":1,"token":"induce"},{"count":1,"token":"Design\/methodology\/approach"},{"count":1,"token":"examine"},{"count":1,"token":"relationship"},{"count":1,"token":"countries"},{"count":1,"token":"using"},{"count":1,"token":"hedonic"},{"count":1,"token":"framework."},{"count":1,"token":"Findings"},{"count":1,"token":"s..."}],"year":2016},"source":"s2","version":"v3-fos"}
197
pes2o-23023365
Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae. We have analyzed the proteins that are oxidatively damaged when Saccharomyces cerevisiae cells are exposed to stressing conditions. Carbonyl groups generated by hydrogen peroxide or menadione on proteins of aerobically respiring cells were detected by Western blotting, purified, and identified. Mitochondrial proteins such as E2 subunits of both pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase, aconitase, heat-shock protein 60, and the cytosolic fatty acid synthase (alpha subunit) and glyceraldehyde-3-phosphate dehydrogenase were the major targets. In addition we also report the in vivo modification of lipoamide present in the above-mentioned E2 subunits under the stressing conditions tested and that this also occurs with the homologous enzymes present in Escherichia coli cells that were used for comparative analysis. Under fermentative conditions, the main protein targets in S. cerevisiae cells treated with hydrogen peroxide or menadione were pyruvate decarboxylase, enolase, fatty acid synthase, and glyceraldehyde-3-phosphate dehydrogenase. Under the stress conditions tested, fermenting cells exhibit a lower viability than aerobically respiring cells and, consistently, increased peroxide generation as well as higher content of protein carbonyls and lipid peroxides. Our results strongly suggest that the oxidative stress in prokaryotic and eukaryotic cells shares common features.
pes2o
{"added":"2018-04-03T01:14:57.187Z","created":"2000-09-01T00:00:00.000Z","id":"28674977","metadata":{"abstract":"We have analyzed the proteins that are oxidatively damaged when Saccharomyces cerevisiae cells are exposed to stressing conditions. Carbonyl groups generated by hydrogen peroxide or menadione on proteins of aerobically respiring cells were detected by Western blotting, purified, and identified. Mitochondrial proteins such as E2 subunits of both pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase, aconitase, heat-shock protein 60, and the cytosolic fatty acid synthase (alpha subunit) and glyceraldehyde-3-phosphate dehydrogenase were the major targets. In addition we also report the in vivo modification of lipoamide present in the above-mentioned E2 subunits under the stressing conditions tested and that this also occurs with the homologous enzymes present in Escherichia coli cells that were used for comparative analysis. Under fermentative conditions, the main protein targets in S. cerevisiae cells treated with hydrogen peroxide or menadione were pyruvate decarboxylase, enolase, fatty acid synthase, and glyceraldehyde-3-phosphate dehydrogenase. Under the stress conditions tested, fermenting cells exhibit a lower viability than aerobically respiring cells and, consistently, increased peroxide generation as well as higher content of protein carbonyls and lipid peroxides. Our results strongly suggest that the oxidative stress in prokaryotic and eukaryotic cells shares common features.","abstract_count":188,"abstract_language":"en","abstract_perplexity":-15.903715501374048,"extfieldsofstudy":["Medicine","Biology"],"provenance":"pes2o_v2-0005.json.gz:3660630","s2fieldsofstudy":["Biology"],"sha1":"5a36ec6dc140a5f1879675daa35aa7a26d19e562","sources":["Adhoc","Anansi","ScienceParseMerged","MergedPDFExtraction","Medline","Unpaywall","MAG"],"title":"Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae.","title_count":9,"title_language":"en","title_perplexity":-16.32472749387695,"top_frequencies":[{"count":10,"token":"the"},{"count":8,"token":"and"},{"count":7,"token":"cells"},{"count":6,"token":"in"},{"count":4,"token":"protein"},{"count":4,"token":"that"},{"count":4,"token":"of"},{"count":4,"token":"were"},{"count":3,"token":"stress"},{"count":3,"token":"proteins"},{"count":3,"token":"peroxide"},{"count":3,"token":"as"},{"count":2,"token":"Saccharomyces"},{"count":2,"token":"are"},{"count":2,"token":"cerevisiae"},{"count":2,"token":"stressing"},{"count":2,"token":"by"},{"count":2,"token":"hydrogen"},{"count":2,"token":"or"},{"count":2,"token":"menadione"},{"count":2,"token":"aerobically"},{"count":2,"token":"respiring"},{"count":2,"token":"E2"},{"count":2,"token":"subunits"},{"count":2,"token":"pyruvate"},{"count":2,"token":"dehydrogenase"},{"count":2,"token":"fatty"},{"count":2,"token":"acid"},{"count":2,"token":"glyceraldehyde-3-phosphate"},{"count":2,"token":"also"},{"count":2,"token":"present"},{"count":2,"token":"conditions"},{"count":2,"token":"with"},{"count":2,"token":"Under"},{"count":1,"token":"Oxidative"},{"count":1,"token":"promotes"},{"count":1,"token":"specific"},{"count":1,"token":"damage"},{"count":1,"token":"cerevisiae."},{"count":1,"token":"We"},{"count":1,"token":"have"},{"count":1,"token":"analyzed"},{"count":1,"token":"oxidatively"},{"count":1,"token":"damaged"},{"count":1,"token":"when"},{"count":1,"token":"exposed"},{"count":1,"token":"to"},{"count":1,"token":"conditions."},{"count":1,"token":"Carbonyl"},{"count":1,"token":"groups"},{"count":1,"token":"generated"},{"count":1,"token":"on"},{"count":1,"token":"detected"},{"count":1,"token":"Western"},{"count":1,"token":"blotting,"},{"count":1,"token":"purified,"},{"count":1,"token":"identified."},{"count":1,"token":"Mitochondrial"},{"count":1,"token":"such"},{"count":1,"token":"both"},{"count":1,"token":"alpha-ketoglutarate"},{"count":1,"token":"dehydrogenase,"},{"count":1,"token":"aconitase,"},{"count":1,"token":"heat-shock"},{"count":1,"token":"60,"},{"count":1,"token":"cytosolic"},{"count":1,"token":"synthase"},{"count":1,"token":"(alpha"},{"count":1,"token":"subunit)"},{"count":1,"token":"major"},{"count":1,"token":"targets."},{"count":1,"token":"In"},{"count":1,"token":"addition"},{"count":1,"token":"we"},{"count":1,"token":"report"},{"count":1,"token":"vivo"},{"count":1,"token":"modification"},{"count":1,"token":"lipoamide"},{"count":1,"token":"above-mentioned"},{"count":1,"token":"under"},{"count":1,"token":"tested"},{"count":1,"token":"this"},{"count":1,"token":"occurs"},{"count":1,"token":"homologous"},{"count":1,"token":"enzymes"},{"count":1,"token":"Escherichia"},{"count":1,"token":"coli"},{"count":1,"token":"used"},{"count":1,"token":"for"},{"count":1,"token":"comparative"},{"count":1,"token":"analysis."},{"count":1,"token":"fermentative"},{"count":1,"token":"conditions,"},{"count":1,"token":"main"},{"count":1,"token":"targets"},{"count":1,"token":"S."},{"count":1,"token":"treated"},{"count":1,"token":"decarboxylase,"},{"count":1,"token":"enolase,"},{"count":1,"token":"synthase,"}],"year":2000},"source":"s2","version":"v3-fos"}
285
pes2o-8323591
ON SINGLE TERM HAAR WAVELET SERIES METHOD FOR VOLTERRA INTEGRO-DIFFERENTIAL EQUATIONS I n this paper present a reliable algorithm for solving Volterra Integro-Differential Equations (VIDE) using single-term Haar wavelet series (STHWS) method. The obtained discrete results were compared with exact solution of the VIDE and methods taken from the literature [1, 4] to highlight the efficiency of the STHWS method. Some illustrative examples have been presented to illustrate the implementation of the algorithm and efficiency of the method.
pes2o
{"added":"2019-04-17T15:40:08.253Z","created":"2014-04-29T00:00:00.000Z","id":"118827902","metadata":{"abstract":"I n this paper present a reliable algorithm for solving Volterra Integro-Differential Equations (VIDE) using single-term Haar wavelet series (STHWS) method. The obtained discrete results were compared with exact solution of the VIDE and methods taken from the literature [1, 4] to highlight the efficiency of the STHWS method. Some illustrative examples have been presented to illustrate the implementation of the algorithm and efficiency of the method.","abstract_count":67,"abstract_language":"en","abstract_perplexity":-15.098250905643908,"extfieldsofstudy":["Mathematics"],"provenance":"pes2o_v2-0002.json.gz:584390","s2fieldsofstudy":["Mathematics"],"sha1":"6a328ac21fc8b056be2a28aa915310beb89211e4","sources":["MAG"],"title":"ON SINGLE TERM HAAR WAVELET SERIES METHOD FOR VOLTERRA INTEGRO-DIFFERENTIAL EQUATIONS","title_count":11,"title_language":"en","title_perplexity":-16.137292092727442,"top_frequencies":[{"count":7,"token":"the"},{"count":4,"token":"of"},{"count":3,"token":"method."},{"count":2,"token":"algorithm"},{"count":2,"token":"and"},{"count":2,"token":"to"},{"count":2,"token":"efficiency"},{"count":1,"token":"ON"},{"count":1,"token":"SINGLE"},{"count":1,"token":"TERM"},{"count":1,"token":"HAAR"},{"count":1,"token":"WAVELET"},{"count":1,"token":"SERIES"},{"count":1,"token":"METHOD"},{"count":1,"token":"FOR"},{"count":1,"token":"VOLTERRA"},{"count":1,"token":"INTEGRO-DIFFERENTIAL"},{"count":1,"token":"EQUATIONS"},{"count":1,"token":"I"},{"count":1,"token":"n"},{"count":1,"token":"this"},{"count":1,"token":"paper"},{"count":1,"token":"present"},{"count":1,"token":"a"},{"count":1,"token":"reliable"},{"count":1,"token":"for"},{"count":1,"token":"solving"},{"count":1,"token":"Volterra"},{"count":1,"token":"Integro-Differential"},{"count":1,"token":"Equations"},{"count":1,"token":"(VIDE)"},{"count":1,"token":"using"},{"count":1,"token":"single-term"},{"count":1,"token":"Haar"},{"count":1,"token":"wavelet"},{"count":1,"token":"series"},{"count":1,"token":"(STHWS)"},{"count":1,"token":"The"},{"count":1,"token":"obtained"},{"count":1,"token":"discrete"},{"count":1,"token":"results"},{"count":1,"token":"were"},{"count":1,"token":"compared"},{"count":1,"token":"with"},{"count":1,"token":"exact"},{"count":1,"token":"solution"},{"count":1,"token":"VIDE"},{"count":1,"token":"methods"},{"count":1,"token":"taken"},{"count":1,"token":"from"},{"count":1,"token":"literature"},{"count":1,"token":"[1,"},{"count":1,"token":"4]"},{"count":1,"token":"highlight"},{"count":1,"token":"STHWS"},{"count":1,"token":"Some"},{"count":1,"token":"illustrative"},{"count":1,"token":"examples"},{"count":1,"token":"have"},{"count":1,"token":"been"},{"count":1,"token":"presented"},{"count":1,"token":"illustrate"},{"count":1,"token":"implementation"}],"year":2014},"source":"s2","version":"v3-fos"}
125
pes2o-4804096
T lymphocytes isolated from the hepatic granulomas of schistosome-infected mice express somatostatin receptor subtype II (SSTR2) messenger RNA. Schistosomiasis mansoni is a disease characterized by liver and intestinal granulomas. Previous investigations in our laboratory showed that nylon wool-adherent CD4+ T lymphocytes isolated from murine hepatic schistosome granulomas express receptors for somatostatin 1-14. Moreover, somatostatin 1-14 substantially decreased IFN-gamma and IgG2a, but not IL-5 secretion by dispersed granuloma cells. This paper extends these observations by defining the somatostatin receptor (SSTR) isoform most likely expressed by granuloma inflammatory lymphocytes. Amplification of mRNA by reverse transcription PCR shows SSTR1, SSTR2, and SSTR3 mRNA in normal mouse brain and other tissues. Nevertheless, only the SSTR2 PCR product was amplified from granuloma cell RNA. The nucleotide sequence of the granuloma SSTR2 PCR product from inflammatory cells is identical to the CBA murine brain SSTR2 cDNA sequence. Granuloma-derived T cell lines, FACS-isolated granuloma CD4+ T cells, thymocytes, splenocytes, and cloned T cell lines all contain mRNA for SSTR2 by reverse transcription PCR. Moreover, both SSTR2A and the splice variant SSTR2B can be amplified from dispersed granuloma cells, granuloma T cell lines, thymocytes, and splenocytes. This is the first demonstration that inflammatory cells produce mRNA for an authentic somatostatin receptor. It is probable that the lymphocyte SSTR2 receptor mediates somatostatin-induced modulation of IFN-gamma secretion.
pes2o
{"added":"2018-04-03T02:54:24.042Z","created":"1994-08-01T00:00:00.000Z","id":"35528221","metadata":{"abstract":"Schistosomiasis mansoni is a disease characterized by liver and intestinal granulomas. Previous investigations in our laboratory showed that nylon wool-adherent CD4+ T lymphocytes isolated from murine hepatic schistosome granulomas express receptors for somatostatin 1-14. Moreover, somatostatin 1-14 substantially decreased IFN-gamma and IgG2a, but not IL-5 secretion by dispersed granuloma cells. This paper extends these observations by defining the somatostatin receptor (SSTR) isoform most likely expressed by granuloma inflammatory lymphocytes. Amplification of mRNA by reverse transcription PCR shows SSTR1, SSTR2, and SSTR3 mRNA in normal mouse brain and other tissues. Nevertheless, only the SSTR2 PCR product was amplified from granuloma cell RNA. The nucleotide sequence of the granuloma SSTR2 PCR product from inflammatory cells is identical to the CBA murine brain SSTR2 cDNA sequence. Granuloma-derived T cell lines, FACS-isolated granuloma CD4+ T cells, thymocytes, splenocytes, and cloned T cell lines all contain mRNA for SSTR2 by reverse transcription PCR. Moreover, both SSTR2A and the splice variant SSTR2B can be amplified from dispersed granuloma cells, granuloma T cell lines, thymocytes, and splenocytes. This is the first demonstration that inflammatory cells produce mRNA for an authentic somatostatin receptor. It is probable that the lymphocyte SSTR2 receptor mediates somatostatin-induced modulation of IFN-gamma secretion.","abstract_count":199,"abstract_language":"en","abstract_perplexity":-17.39767455331157,"extfieldsofstudy":["Biology","Medicine"],"provenance":"pes2o_v2-0001.json.gz:941565","s2fieldsofstudy":["Biology","Medicine"],"sha1":"3f0a333ba6abbf7995ae00f82edf43fe50c1a5ee","sources":["Medline","MAG"],"title":"T lymphocytes isolated from the hepatic granulomas of schistosome-infected mice express somatostatin receptor subtype II (SSTR2) messenger RNA.","title_count":18,"title_language":"en","title_perplexity":-18.425371859176742,"top_frequencies":[{"count":8,"token":"the"},{"count":7,"token":"and"},{"count":7,"token":"granuloma"},{"count":6,"token":"T"},{"count":6,"token":"by"},{"count":5,"token":"from"},{"count":5,"token":"somatostatin"},{"count":5,"token":"SSTR2"},{"count":4,"token":"of"},{"count":4,"token":"is"},{"count":4,"token":"mRNA"},{"count":4,"token":"cell"},{"count":3,"token":"receptor"},{"count":3,"token":"that"},{"count":3,"token":"for"},{"count":3,"token":"inflammatory"},{"count":3,"token":"PCR"},{"count":2,"token":"lymphocytes"},{"count":2,"token":"isolated"},{"count":2,"token":"hepatic"},{"count":2,"token":"granulomas"},{"count":2,"token":"express"},{"count":2,"token":"RNA."},{"count":2,"token":"in"},{"count":2,"token":"CD4+"},{"count":2,"token":"murine"},{"count":2,"token":"Moreover,"},{"count":2,"token":"IFN-gamma"},{"count":2,"token":"dispersed"},{"count":2,"token":"This"},{"count":2,"token":"reverse"},{"count":2,"token":"transcription"},{"count":2,"token":"brain"},{"count":2,"token":"product"},{"count":2,"token":"amplified"},{"count":2,"token":"cells"},{"count":2,"token":"lines,"},{"count":2,"token":"cells,"},{"count":2,"token":"thymocytes,"},{"count":1,"token":"schistosome-infected"},{"count":1,"token":"mice"},{"count":1,"token":"subtype"},{"count":1,"token":"II"},{"count":1,"token":"(SSTR2)"},{"count":1,"token":"messenger"},{"count":1,"token":"Schistosomiasis"},{"count":1,"token":"mansoni"},{"count":1,"token":"a"},{"count":1,"token":"disease"},{"count":1,"token":"characterized"},{"count":1,"token":"liver"},{"count":1,"token":"intestinal"},{"count":1,"token":"granulomas."},{"count":1,"token":"Previous"},{"count":1,"token":"investigations"},{"count":1,"token":"our"},{"count":1,"token":"laboratory"},{"count":1,"token":"showed"},{"count":1,"token":"nylon"},{"count":1,"token":"wool-adherent"},{"count":1,"token":"schistosome"},{"count":1,"token":"receptors"},{"count":1,"token":"1-14."},{"count":1,"token":"1-14"},{"count":1,"token":"substantially"},{"count":1,"token":"decreased"},{"count":1,"token":"IgG2a,"},{"count":1,"token":"but"},{"count":1,"token":"not"},{"count":1,"token":"IL-5"},{"count":1,"token":"secretion"},{"count":1,"token":"cells."},{"count":1,"token":"paper"},{"count":1,"token":"extends"},{"count":1,"token":"these"},{"count":1,"token":"observations"},{"count":1,"token":"defining"},{"count":1,"token":"(SSTR)"},{"count":1,"token":"isoform"},{"count":1,"token":"most"},{"count":1,"token":"likely"},{"count":1,"token":"expressed"},{"count":1,"token":"lymphocytes."},{"count":1,"token":"Amplification"},{"count":1,"token":"shows"},{"count":1,"token":"SSTR1,"},{"count":1,"token":"SSTR2,"},{"count":1,"token":"SSTR3"},{"count":1,"token":"normal"},{"count":1,"token":"mouse"},{"count":1,"token":"other"},{"count":1,"token":"tissues."},{"count":1,"token":"Nevertheless,"},{"count":1,"token":"only"},{"count":1,"token":"was"},{"count":1,"token":"The"},{"count":1,"token":"nucleotide"},{"count":1,"token":"sequence"},{"count":1,"token":"identical"},{"count":1,"token":"to"}],"year":1994},"source":"s2","version":"v3-fos"}
340
pes2o-18739922
“Ditch red meat and dairy, and don’t bother with local food”: The problem with universal dietary advice aiming to save the planet (and your health) In recent years there have been increasing calls for “global dietary transition” in order to save the planet and improve human health. One troubling development associated with this is the attempt to delineate in universal terms what constitutes a sustainable and healthy diet. This perspective takes issue with this development, and specifically refutes one increasingly popular dietary narrative which calls for people to avoid red meat and dairy, and which portrays the local food movement as a romantic distraction. In contrast, the paper provides evidence of a range of sustainability and health benefits associated with both local food systems and the agri-food system’s inclusion of ruminants (the suborder of mammals from which humans mostly derive red meat and dairy). Finally, the perspective calls for a pluralist and multi-scalar approach to the multifaceted challenges associated with food production.
pes2o
{"added":"2020-11-19T09:17:21.590Z","created":"2020-11-16T00:00:00.000Z","id":"228899736","metadata":{"abstract":"In recent years there have been increasing calls for \u201cglobal dietary transition\u201d in order to save the planet and improve human health. One troubling development associated with this is the attempt to delineate in universal terms what constitutes a sustainable and healthy diet. This perspective takes issue with this development, and specifically refutes one increasingly popular dietary narrative which calls for people to avoid red meat and dairy, and which portrays the local food movement as a romantic distraction. In contrast, the paper provides evidence of a range of sustainability and health benefits associated with both local food systems and the agri-food system\u2019s inclusion of ruminants (the suborder of mammals from which humans mostly derive red meat and dairy). Finally, the perspective calls for a pluralist and multi-scalar approach to the multifaceted challenges associated with food production.","abstract_count":137,"abstract_language":"en","abstract_perplexity":-13.141843671972184,"extfieldsofstudy":["Business"],"provenance":"pes2o_v2-0004.json.gz:3253315","s2fieldsofstudy":["Agricultural And Food Sciences"],"sha1":"c4da8a6d190e5839654306be5edee07667f1a6d9","sources":["Crossref","Unpaywall","MAG"],"title":"\u201cDitch red meat and dairy, and don\u2019t bother with local food\u201d: The problem with universal dietary advice aiming to save the planet (and your health)","title_count":25,"title_language":"en","title_perplexity":-15.114416044634172,"top_frequencies":[{"count":11,"token":"and"},{"count":8,"token":"the"},{"count":6,"token":"with"},{"count":5,"token":"to"},{"count":4,"token":"a"},{"count":4,"token":"of"},{"count":3,"token":"red"},{"count":3,"token":"meat"},{"count":3,"token":"local"},{"count":3,"token":"dietary"},{"count":3,"token":"calls"},{"count":3,"token":"for"},{"count":3,"token":"associated"},{"count":3,"token":"which"},{"count":3,"token":"food"},{"count":2,"token":"dairy,"},{"count":2,"token":"universal"},{"count":2,"token":"save"},{"count":2,"token":"planet"},{"count":2,"token":"In"},{"count":2,"token":"in"},{"count":2,"token":"this"},{"count":2,"token":"perspective"},{"count":1,"token":"\u201cDitch"},{"count":1,"token":"don\u2019t"},{"count":1,"token":"bother"},{"count":1,"token":"food\u201d:"},{"count":1,"token":"The"},{"count":1,"token":"problem"},{"count":1,"token":"advice"},{"count":1,"token":"aiming"},{"count":1,"token":"(and"},{"count":1,"token":"your"},{"count":1,"token":"health)"},{"count":1,"token":"recent"},{"count":1,"token":"years"},{"count":1,"token":"there"},{"count":1,"token":"have"},{"count":1,"token":"been"},{"count":1,"token":"increasing"},{"count":1,"token":"\u201cglobal"},{"count":1,"token":"transition\u201d"},{"count":1,"token":"order"},{"count":1,"token":"improve"},{"count":1,"token":"human"},{"count":1,"token":"health."},{"count":1,"token":"One"},{"count":1,"token":"troubling"},{"count":1,"token":"development"},{"count":1,"token":"is"},{"count":1,"token":"attempt"},{"count":1,"token":"delineate"},{"count":1,"token":"terms"},{"count":1,"token":"what"},{"count":1,"token":"constitutes"},{"count":1,"token":"sustainable"},{"count":1,"token":"healthy"},{"count":1,"token":"diet."},{"count":1,"token":"This"},{"count":1,"token":"takes"},{"count":1,"token":"issue"},{"count":1,"token":"development,"},{"count":1,"token":"specifically"},{"count":1,"token":"refutes"},{"count":1,"token":"one"},{"count":1,"token":"increasingly"},{"count":1,"token":"popular"},{"count":1,"token":"narrative"},{"count":1,"token":"people"},{"count":1,"token":"avoid"},{"count":1,"token":"portrays"},{"count":1,"token":"movement"},{"count":1,"token":"as"},{"count":1,"token":"romantic"},{"count":1,"token":"distraction."},{"count":1,"token":"contrast,"},{"count":1,"token":"paper"},{"count":1,"token":"provides"},{"count":1,"token":"evidence"},{"count":1,"token":"range"},{"count":1,"token":"sustainability"},{"count":1,"token":"health"},{"count":1,"token":"benefits"},{"count":1,"token":"both"},{"count":1,"token":"systems"},{"count":1,"token":"agri-food"},{"count":1,"token":"system\u2019s"},{"count":1,"token":"inclusion"},{"count":1,"token":"ruminants"},{"count":1,"token":"(the"},{"count":1,"token":"suborder"},{"count":1,"token":"mammals"},{"count":1,"token":"from"},{"count":1,"token":"humans"},{"count":1,"token":"mostly"},{"count":1,"token":"derive"},{"count":1,"token":"dairy)."},{"count":1,"token":"Finally,"},{"count":1,"token":"pluralist"},{"count":1,"token":"multi-scalar"}],"year":2020},"source":"s2","version":"v3-fos"}
200
wikipedia-4648968
Cowboys–Rams rivalry The Cowboys–Rams rivalry is a National Football League (NFL) rivalry between the Dallas Cowboys and the Los Angeles Rams. The two teams do not play every year; instead, they play once every three years due to the NFL's rotating division schedules, or if the two teams finish in the same place in their respective divisions, they would play the ensuing season. The rivalry between the two teams peaked during the 1970s and early-to-mid 1980s, during which they met eight times in the playoffs, with each team winning four. History. The rivalry between the Cowboys and Rams started once Dallas joined the NFL as an expansion team in . They were one of the first two teams to conduct joint practices during the preseason. Initially, the rivalry became a friendly one owing to the friendship between Rams owner Dan Reeves and Cowboys executive Tex Schramm. However, the feud intensified after Schramm accused Rams head coach George Allen of sending a spy to a Cowboys practice, to which Allen countered by arguing that the Cowboys put a scout atop a tree to spy on the Rams. The Cowboys and Rams faced each other in the playoffs for the first time in . Dallas was coached by Tom Landry, and featured Roger Staubach as the quarterback and the Doomsday Defense led by Hall of Famer Bob Lilly. The Rams, coached by Chuck Knox, featured defensive stalwarts in Jack Youngblood and Merlin Olsen. In that first meeting, the Cowboys prevailed 27–16 at Texas Stadium in the . Two seasons later, the two teams met in the at the Los Angeles Memorial Coliseum. Despite entering the game as heavy favorites, the Rams lost in a blowout at home, 37–7, sending the Cowboys to their third Super Bowl appearance. However, the Rams returned the favor in the , winning a close 14–12 decision in Dallas. It was also the Rams' first road playoff victory. As was the case in 1975, the resulted in a blowout victory for the Cowboys on the road, winning 28–0 and clinched the team's fifth Super Bowl appearance. The Cowboys lost both of those games to the Pittsburgh Steelers. But in a similar fashion to 1976, the Rams bounced back in a chippy low-scoring encounter, winning the 21–19 in Dallas. In that game, Rams quarterback Vince Ferragamo threw three touchdown passes, the last of which gave the Rams the lead for good. This game was also notable as it marked the final game of Roger Staubach's career. The Rams eventually advance to their first Super Bowl, but lost to the Steelers. The two teams met in the playoffs for a third consecutive time, this time in the . In that game, the Cowboys routed the Rams at home, winning 34–13. The 1980s saw a Cowboys team in transition, now featuring Danny White as its starting quarterback. Meanwhile, the Rams drafted running back Eric Dickerson in the 1983 NFL Draft and quickly became the face of the franchise. The next two playoff meetings resulted in Rams victories. In the , the Rams stunned the heavily favored Cowboys 24–17 in Dallas, with White committing three interceptions. Then in the , Dickerson rushed for a playoff record 248 yards and two touchdowns as the Rams shut out the Cowboys 20–0 in Anaheim Stadium. The game marked Tom Landry's final playoff game as Cowboys head coach, as well as the final NFL playoff game in Anaheim (the Rams moved there in 1980). The rivalry became dormant over the next two decades. While the Cowboys became a Super Bowl dynasty in the 1990s and remained a relevant franchise in subsequent years, the Rams struggled with nine consecutive losing seasons, during which the team relocated to St. Louis in . The Rams eventually won Super Bowl XXXIV in behind The Greatest Show on Turf trio of Kurt Warner, Marshall Faulk and Isaac Bruce, but it also coincided with the decline of the Cowboys' Super Bowl-winning core featuring Troy Aikman, Michael Irvin and Emmitt Smith. In 2002, the Cowboys met the Rams for the first time since the latter's move to St. Louis; it was also their first meeting overall since , a 27–23 Rams win on the road. In Dallas' first visit to Edward Jones Dome, the Cowboys prevailed 13–10. The Cowboys made two more visits to St. Louis in 2008 and 2014, splitting those meetings. After the 2015 season, the Rams returned to Los Angeles, and gradually reemerged as a Super Bowl contender. In , the Rams and Cowboys met in the playoffs for the first time since 1985. In the , the Rams prevailed 30–22 and went on to play in Super Bowl LIII in a losing cause to the New England Patriots. The game marked the Cowboys' final visit to the Los Angeles Memorial Coliseum. The season saw the Rams move to SoFi Stadium, and on September 13, the stadium hosted its first-ever game with the Cowboys as the visiting team. The Rams won 20–17. Game results. ! 1973 playoffs ! style="| Cowboys &lt;br&gt; 27–16 ! Texas Stadium ! Rams &lt;br&gt; 4–3 ! NFC Divisional Round. First post-season meeting between the teams. ! 1975 playoffs ! style="| Cowboys &lt;br&gt; 37–7 ! Los Angeles Memorial Coliseum ! Cowboys &lt;br&gt; 5–4 ! NFC Championship Game. Cowboys take first lead in the series. Cowboys lose Super Bowl X. ! 1976 playoffs ! style="| Rams &lt;br&gt; 14–12 ! Texas Stadium ! Tied &lt;br&gt; 5–5 ! NFC Divisional Round. Final meeting in the series for Rams defensive tackle Merlin Olsen. Final meeting for head coach Chuck Knox during his first stint as Rams head coach. ! 1978 playoffs ! style="| Cowboys &lt;br&gt; 28–0 ! Los Angeles Memorial Coliseum ! Tied &lt;br&gt; 6–6 ! NFC Championship Game. Final meeting at Los Angeles Memorial Coliseum until 2018. Cowboys lose Super Bowl XIII. ! 1979 playoffs ! style="| Rams &lt;br&gt; 21–19 ! Texas Stadium ! Tied &lt;br&gt; 7–7 ! NFC Divisional Round. Final start in the series for Roger Staubach. Rams lose Super Bowl XIV. ! 1980 playoffs ! style="| Cowboys &lt;br&gt; 34–13 ! Texas Stadium ! Tied &lt;br&gt; 8–8 ! NFC Wild Card Round. ! 1983 playoffs ! style="| Rams &lt;br&gt; 24–17 ! Texas Stadium ! Tied &lt;br&gt; 9–9 ! NFC Wild Card Round. First meeting in the series for John Robinson as Rams head coach and Rams running back Eric Dickerson. ! 1985 playoffs ! style="| Rams &lt;br&gt; 20–0 ! Anaheim Stadium ! Tied &lt;br&gt; 10–10 ! NFC Divisional Round. Final playoff game at Anaheim Stadium. Final playoff game for Cowboys head coach Tom Landry. Eighth postseason meeting in just a 13-year period. ! 2018 playoffs ! style="| Rams &lt;br&gt; 30–22 ! Los Angeles Memorial Coliseum ! Tied &lt;br&gt; 17–17 ! NFC Divisional Round. Final meeting at Los Angeles Memorial Coliseum. Ninth postseason meeting, ties NFL record. Rams lose Super Bowl LIII. First postseason meeting since 1985 NFC Divisional Playoff game.
wikipedia
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