query: what organ produces chyme as a result of mechanical digestion

pos: Chyme Chyme Chyme or chymus (; from Greek χυμός "khymos", "juice") is the semi-fluid mass of partly digested food that is expelled by the stomach, through the pyloric valve, into the duodenum (the beginning of the small intestine). Chyme results from the mechanical and chemical breakdown of a bolus and consists of partially digested food, water, hydrochloric acid, and various digestive enzymes. Chyme slowly passes through the pyloric sphincter and into the duodenum, where the extraction of nutrients begins. Depending on the quantity and contents of the meal, the stomach will digest the food into chyme in anywhere between 40 minutes

pos: Chyme will be absorbed along with other nutrients. Chyme has a low pH that is countered by the production of bile, helping to further digest food. Chyme is part liquid and part solid: a thick semifluid mass of partially digested food and digestive secretions that is formed in the stomach and small intestine during digestion. Chyme also contains cells from the mouth and esophagus that slough off from the mechanical action of chewing and swallowing. After hours of mechanical and chemical digestion, food has been reduced into chyme. As particles of food become small enough, they are passed out of the

pos: Stomach Stomach The stomach (from ancient Greek στόμαχος, "stomachos," "stoma" means mouth) is a muscular, hollow organ in the gastrointestinal tract of humans and many other animals, including several invertebrates. The stomach has a dilated structure and functions as a vital digestive organ. In the digestive system the stomach is involved in the second phase of digestion, following mastication (chewing). In humans and many other animals, the stomach is located between the oesophagus and the small intestine. It secretes digestive enzymes and gastric acid to aid in food digestion. The pyloric sphincter controls the passage of partially digested food (chyme) from

pos: Digestion that move along the stomach wall. This allows the mass of food to further mix with the digestive enzymes. After some time (typically 1–2 hours in humans, 4–6 hours in dogs, 3–4 hours in house cats), the resulting thick liquid is called chyme. When the pyloric sphincter valve opens, chyme enters the duodenum where it mixes with digestive enzymes from the pancreas and bile juice from the liver and then passes through the small intestine, in which digestion continues. When the chyme is fully digested, it is absorbed into the blood. 95% of absorption of nutrients occurs in the small

pos: Peristalsis intestine. Once past the stomach, a typical peristaltic wave only lasts for a few seconds, travelling at only a few centimeters per second. Its primary purpose is to mix the chyme in the intestine rather than to move it forward in the intestine. Through this process of mixing and continued digestion and absorption of nutrients, the chyme gradually works its way through the small intestine to the large intestine. In contrast to peristalsis, segmentation contractions result in that churning and mixing without pushing materials further down the digestive tract. Although the large intestine has peristalsis of the type that the

pos: Human digestive system fats to some degree though is not as efficient as the pancreatic lipase. The pylorus, the lowest section of the stomach which attaches to the duodenum via the pyloric canal, contains countless glands which secrete digestive enzymes including gastrin. After an hour or two, a thick semi-liquid called chyme is produced. When the pyloric sphincter, or valve opens, chyme enters the duodenum where it mixes further with digestive enzymes from the pancreas, and then passes through the small intestine, where digestion continues. When the chyme is fully digested, it is absorbed into the blood. 95% of absorption of nutrients occurs

pos: Bolus (digestion) Bolus (digestion) In digestion, a bolus (from Latin "bolus", "ball") is a ball-like mixture of food and saliva that forms in the mouth during the process of chewing (which is largely an adaptation for plant-eating mammals). It has the same color as the food being eaten, and the saliva gives it an alkaline pH. Under normal circumstances, the bolus is swallowed, and travels down the esophagus to the stomach for digestion. Once the bolus reaches the stomach, it mixes with gastric juices and becomes chyme, which then travels through the intestines for further digestion and absorption, and eventual discharge as

pos: Bolus (digestion) feces. Bolus (digestion) In digestion, a bolus (from Latin "bolus", "ball") is a ball-like mixture of food and saliva that forms in the mouth during the process of chewing (which is largely an adaptation for plant-eating mammals). It has the same color as the food being eaten, and the saliva gives it an alkaline pH. Under normal circumstances, the bolus is swallowed, and travels down the esophagus to the stomach for digestion. Once the bolus reaches the stomach, it mixes with gastric juices and becomes chyme, which then travels through the intestines for further digestion and absorption, and eventual discharge

pos: Chyme the chyme to 7. The chyme then moves through the jejunum and the ileum, where digestion progresses, and the nonuseful portion continues onward into the large intestine. The duodenum is protected by a thick layer of mucus and the neutralizing actions of the sodium bicarbonate and bile. At a pH of 7, the enzymes that were present from the stomach are no longer active. This then leads into the further breakdown of the nutrients still present by anaerobic bacteria, which at the same time help to package the remains. These bacteria also help synthesize vitamin B and vitamin K, which

pos: Digestion benefits: it denatures proteins for further digestion in the small intestines, and provides non-specific immunity, damaging or eliminating various pathogens. In the small intestines, the duodenum provides critical pH balancing to activate digestive enzymes. The liver secretes bile into the duodenum to neutralize the acidic conditions from the stomach, and the pancreatic duct empties into the duodenum, adding bicarbonate to neutralize the acidic chyme, thus creating a neutral environment. The mucosal tissue of the small intestines is alkaline with a pH of about 8.5. Digestion Digestion is the breakdown of large insoluble food molecules into small water-soluble food molecules so

pos: Secretin smaller numbers in the jejunum of the small intestine. Secretin is released into circulation and/or intestinal lumen in response to low duodenal pH that ranges between 2 and 4.5 depending on species; the acidity is due to hydrochloric acid in the chyme that enters the duodenum from the stomach via the pyloric sphincter. Also, the secretion of secretin is increased by the products of protein digestion bathing the mucosa of the upper small intestine. Secretin release is inhibited by H antagonists, which reduce gastric acid secretion. As a result, if the pH in the duodenum increases above 4.5, secretin cannot

pos: Human digestive system the stomach. It connects to the duodenum via the pancreatic duct which it joins near to the bile duct's connection where both the bile and pancreatic juice can act on the chyme that is released from the stomach into the duodenum. Aqueous pancreatic secretions from pancreatic duct cells contain bicarbonate ions which are alkaline and help with the bile to neutralise the acidic chyme that is churned out by the stomach. The pancreas is also the main source of enzymes for the digestion of fats and proteins. Some of these are released in response to the production of CKK in

pos: Human digestive system teeth, and also by the contractions of peristalsis, and segmentation. Gastric acid, and the production of mucus in the stomach, are essential for the continuation of digestion. Peristalsis is the rhythmic contraction of muscles that begins in the esophagus and continues along the wall of the stomach and the rest of the gastrointestinal tract. This initially results in the production of chyme which when fully broken down in the small intestine is absorbed as chyle into the lymphatic system. Most of the digestion of food takes place in the small intestine. Water and some minerals are reabsorbed back into the

pos: Chyme to 3 hours at most. The chyme is blue in color. With a pH of approximately 2, chyme emerging from the stomach is very acidic. The duodenum secretes a hormone, cholecystokinin (CCK), which causes the gall bladder to contract, releasing alkaline bile into the duodenum. CCK also causes the release of digestive enzymes from the pancreas. The duodenum is a short section of the small intestine located between the stomach and the rest of the small intestine. The duodenum also produces the hormone secretin to stimulate the pancreatic secretion of large amounts of sodium bicarbonate, which then raises pH of

pos: Proventriculus Proventriculus The proventriculus is part of the digestive system of birds. An analogous organ exists in invertebrates and insects. The proventriculus is a standard part of avian anatomy, and is a rod shaped organ, located between the oesophagus and the gizzard of most birds. It is generally a glandular part of the stomach that may store and/or commence digestion of food before it progresses to the gizzard. The primary function of the proventriculus is to secrete Hydrochloric acid and Pepsinogen into the digestive compartments that will churn the ingested material through muscular mechanisms. Pepsinogen produces pepsin, which breaks the peptide

pos: Human digestive system The duodenum is the first and shortest section of the small intestine. It is a hollow, jointed C-shaped tube connecting the stomach to the jejunum. It starts at the duodenal bulb and ends at the suspensory muscle of duodenum. The attachment of the suspensory muscle to the diaphragm is thought to help the passage of food by making a wider angle at its attachment. Most food digestion takes place in the small intestine. Segmentation contractions act to mix and move the chyme more slowly in the small intestine allowing more time for absorption (and these continue in the large intestine).

pos: Regulation of gastric function absorbed by the duodenum stimulate acid secretion by unknown mechanisms. 4.) Osmolarity due to products of digestion stimulate acid secretion The acid and semi-digested fats in the duodenum trigger the enterogastric reflex – the duodenum sends inhibitory signals to the stomach by way of the enteric nervous system, and sends signals to the medulla that (1) inhibit the vagal nuclei, thus reducing vagal stimulation of the stomach, and (2) stimulate sympathetic neurons, which send inhibitory signals to the stomach. Chyme also stimulates duodenal enteroendocrine cells to release secretin and cholecystokinin. They primarily stimulate the pancreas and gall bladder, but also

pos: Chyme starches in chyme that were not digested fully in the small intestine. When all of the nutrients have been absorbed from chyme, the remaining waste material changes into semisolids that are called feces. The feces pass to the rectum, to be stored until ready to be discharged from the body during defecation. The chyme of an unweaned calf is the defining ingredient of pajata, a traditional Roman recipe. Chyme Chyme or chymus (; from Greek χυμός "khymos", "juice") is the semi-fluid mass of partly digested food that is expelled by the stomach, through the pyloric valve, into the duodenum (the

pos: Lipid metabolism intestinal wall. In the epithelial cells, fatty acids are packaged and transported to the rest of the body. Digestion is the first step to lipid metabolism, and it is the process of breaking the triglycerides down into smaller monoglyceride units with the help of lipase enzymes. Digestion of fats begin in the mouth through chemical digestion by lingual lipase. Ingested cholesterol is not broken down by the lipases and stays intact until it enters the epithelium cells of small intestine. Lipids then continue to the stomach where chemical digestion continues by gastric lipase and mechanical digestion begins (Peristalsis). The majority

pos: Digestion small, round slurry mass called a bolus. It will then travel down the esophagus and into the stomach by the action of peristalsis. Gastric juice in the stomach starts protein digestion. Gastric juice mainly contains hydrochloric acid and pepsin. It also contains rennin in case of infants and toddlers. As the first two chemicals may damage the stomach wall, mucus is secreted by the stomach, providing a slimy layer that acts as a shield against the damaging effects of the chemicals. At the same time protein digestion is occurring, mechanical mixing occurs by peristalsis, which is waves of muscular contractions

pos: Exocrine pancreatic insufficiency genetic conditions, a blocked pancreatic duct, or prior infection. The exocrine pancreas is a portion of this organ that contains clusters of ducts (acini) producing bicarbonate anion, a mild alkali, as well as an array of digestive enzymes that together empty by way of the interlobular and main pancreatic ducts into the duodenum (upper small intestine). The hormones cholecystokinin and secretin secreted by the stomach and duodenum in response to distension and the presence of food in turn stimulate the production of digestive enzymes by the exocrine pancreas. The alkalization of the duodenum neutralizes the acidic chyme produced by the

pos: Digestion cephalic phase in which saliva is produced in the mouth and digestive enzymes are produced in the stomach. Mechanical and chemical digestion begin in the mouth where food is chewed, and mixed with saliva to begin enzymatic processing of starches. The stomach continues to break food down mechanically and chemically through churning and mixing with both acids and enzymes. Absorption occurs in the stomach and gastrointestinal tract, and the process finishes with defecation. The human gastrointestinal tract is around 9 meters long. Food digestion physiology varies between individuals and upon other factors such as the characteristics of the food and

pos: Bicarbonate acts to regulate pH in the small intestine. It is released from the pancreas in response to the hormone secretin to neutralize the acidic chyme entering the duodenum from the stomach. Bicarbonate is the dominant form of dissolved inorganic carbon in sea water, and in most fresh waters. As such it is an important sink in the carbon cycle. In freshwater ecology, strong photosynthetic activity by freshwater plants in daylight releases gaseous oxygen into the water and at the same time produces bicarbonate ions. These shift the pH upward until in certain circumstances the degree of alkalinity can become toxic

pos: Digestion size of the meal, and the process of digestion normally takes between 24 and 72 hours. Digestion begins in the mouth with the secretion of saliva and its digestive enzymes. Food is formed into a bolus by the mechanical mastication and swallowed into the esophagus from where it enters the stomach through the action of peristalsis. Gastric juice contains hydrochloric acid and pepsin which would damage the walls of the stomach and mucus is secreted for protection. In the stomach further release of enzymes break down the food further and this is combined with the churning action of the stomach.

pos: Spleen (Chinese medicine) Spleen (Chinese medicine) The Spleen () is one of the zàng organs stipulated by Traditional Chinese Medicine (TCM). It is a functionally defined entity and not equivalent to the anatomical organ of the same name. As a zàng, the Spleen is considered to be a yin organ. Its associated yang organ is the Stomach. Both Spleen and Stomach are attributed to the Earth element. Regarding its stipulated functions, the Spleen Its associated body fluid is saliva. The Spleen's function (i.e., the Spleen-qì) is said to be strongest between 9 and 11am. When the Spleen is functioning well, digestion will be

neg: Ileum into the lumen of the intestine. These enzymes are present in the cytoplasm of the epithelial cells. The villi contain large numbers of capillaries that take the amino acids and glucose produced by digestion to the hepatic portal vein and the liver. Lacteals are small lymph vessels, and are present in villi. They absorb fatty acid and glycerol, the products of fat digestion. Layers of circular and longitudinal smooth muscle enable the chyme (partly digested food and water) to be pushed along the ileum by waves of muscle contractions called peristalsis. The remaining chyme is passed to the colon. It

neg: Large intestine more is made available, thus permitting a higher portion of plant material in the diet. The large intestine produces no digestive enzymes — chemical digestion is completed in the small intestine before the chyme reaches the large intestine. The pH in the colon varies between 5.5 and 7 (slightly acidic to neutral). Water absorption at the colon typically proceeds against a transmucosal osmotic pressure gradient. The standing gradient osmosis is the reabsorption of water against the osmotic gradient in the intestines. Cells occupying the intestinal lining pump sodium ions into the intercellular space, raising the osmolarity of the intercellular fluid.

neg: Large intestine the water have been absorbed by the body. At this point some electrolytes like sodium, magnesium, and chloride are left as well as indigestible parts of ingested food (e.g., a large part of ingested amylose, starch which has been shielded from digestion heretofore, and dietary fiber, which is largely indigestible carbohydrate in either soluble or insoluble form). As the chyme moves through the large intestine, most of the remaining water is removed, while the chyme is mixed with mucus and bacteria (known as gut flora), and becomes feces. The ascending colon receives fecal material as a liquid. The muscles of

neg: Human digestive system Human digestive system The human digestive system consists of the gastrointestinal tract plus the accessory organs of digestion (the tongue, salivary glands, pancreas, liver, and gallbladder). Digestion involves the breakdown of food into smaller and smaller components, until they can be absorbed and assimilated into the body. The process of digestion has many stages. The first stage is the cephalic phase of digestion which begins with gastric secretions in response to the sight and smell of food. The next stage starts in the mouth. Chewing, in which food is mixed with saliva, begins the mechanical process of digestion. This produces

neg: Insulin resistance Insulin resistance Insulin resistance (IR) is considered as a pathological condition in which cells fail to respond normally to the hormone insulin. To prevent hyperglycemia and noticeable organ damage over time, the body produces insulin when glucose starts to be released into the bloodstream, primarily from the digestion of carbohydrates in the diet. Under normal conditions of insulin reactivity, this insulin response triggers glucose being taken into body cells, to be used for energy, and inhibits the body from using fat for energy, thereby causing the concentration of glucose in the blood to decrease as a result, staying within the

neg: Liver insulin/Insulin-like growth factor (IGF) Liver The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion. In humans, it is located in the right upper quadrant of the abdomen, below the diaphragm. Its other roles in metabolism include the regulation of glycogen storage, decomposition of red blood cells and the production of hormones. The liver is an accessory digestive gland that produces bile, an alkaline compound which helps the breakdown of fat. Bile aids in digestion via the emulsification of lipids. The gallbladder, a small pouch that sits just under the liver,

neg: Liver Liver The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion. In humans, it is located in the right upper quadrant of the abdomen, below the diaphragm. Its other roles in metabolism include the regulation of glycogen storage, decomposition of red blood cells and the production of hormones. The liver is an accessory digestive gland that produces bile, an alkaline compound which helps the breakdown of fat. Bile aids in digestion via the emulsification of lipids. The gallbladder, a small pouch that sits just under the liver, stores bile produced by

neg: Chyme stomach at regular intervals into the small intestine, which stimulates the pancreas to release fluid containing a high concentration of bicarbonate. This fluid neutralizes the gastric juices, which can damage the lining of the intestine and result in duodenal ulcer. Other secretions from the pancreas, gallbladder, liver, and glands in the intestinal wall help in digestion. When food particles are sufficiently reduced in size and composition, they are absorbed by the intestinal wall and transported to the bloodstream. Some food material is passed from the small intestine to the large intestine. In the large intestine, bacteria break down proteins and

neg: Digestion The partially digested food enters the duodenum as a thick semi-liquid chyme. In the small intestine, the larger part of digestion takes place and this is helped by the secretions of bile, pancreatic juice and intestinal juice. The intestinal walls are lined with villi, and their epithelial cells is covered with numerous microvilli to improve the absorption of nutrients by increasing the surface area of the intestine. In the large intestine the passage of food is slower to enable fermentation by the gut flora to take place. Here water is absorbed and waste material stored as feces to be removed

neg: Human digestive system In the duodenum, pancreatic lipase is secreted together with a co-enzyme, colipase to further digest the fat content of the chyme. From this breakdown, smaller particles of emulsified fats called chylomicrons are produced. There are also digestive cells called enterocytes lining the intestines (the majority being in the small intestine). They are unusual cells in that they have villi on their surface which in turn have innumerable microvilli on their surface. All these villi make for a greater surface area, not only for the absorption of chyme but also for its further digestion by large numbers of digestive enzymes present

neg: Human digestive system its nutrients the remaining waste material changes into the semi-solids called feces, which pass to the large intestine, where bacteria in the gut flora further break down residual proteins and starches. The cecum is a pouch marking the division between the small intestine and the large intestine. The cecum receives chyme from the last part of the small intestine, the ileum, and connects to the ascending colon of the large intestine. At this junction there is a sphincter or valve, the ileocecal valve which slows the passage of chyme from the ileum, allowing further digestion. It is also the site

neg: Imhoff tank in the lower digestion chamber. The lower chamber requires separate biogas vents and pipes for the removal of digested sludge, typically after 6-9 months of digestion. The Imhoff tank is in effect a two-story septic tank and retains the septic tank's simplicity while eliminating many of its drawbacks, which largely result from the mixing of fresh sewage and septic sludge in the same chamber. Imhoff tanks are being superseded in sewage treatment by plain sedimentation tanks using mechanical methods for continuously collecting the sludge, which is moved to separate digestion tanks. This arrangement permits both improved sedimentation results and better

neg: Digestion Digestion Digestion is the breakdown of large insoluble food molecules into small water-soluble food molecules so that they can be absorbed into the watery blood plasma. In certain organisms, these smaller substances are absorbed through the small intestine into the blood stream. Digestion is a form of catabolism that is often divided into two processes based on how food is broken down: mechanical and chemical digestion. The term mechanical digestion refers to the physical breakdown of large pieces of food into smaller pieces which can subsequently be accessed by digestive enzymes. In chemical digestion, enzymes break down food into the

neg: Duodenum stomach via hormonal pathways. Secretin and cholecystokinin are released from cells in the duodenal epithelium in response to acidic and fatty stimuli present there when the pylorus opens and emits gastric chyme into the duodenum for further digestion. These cause the liver and gall bladder to release bile, and the pancreas to release bicarbonate and digestive enzymes such as trypsin, lipase and amylase into the duodenum as they are needed. The villi of the duodenum have a leafy-looking appearance, which is a histologically identifiable structure. Brunner's glands, which secrete mucus, are found in the duodenum "only". The duodenum wall consists

neg: Use of DNA in forensic entomology to be a fragment of adult insect cuticle, or what appeared to be a fragment of insect pupal cuticle (puparium). A DNA extraction procedure was performed on each specimen using the commercial kit sold by Qiagen. Each sample was subjected to chemical digestion but no deliberate mechanical damage. The middle portion was cut out of the body of the larvae specimens for digestion and DNA extraction following the manufacturer's instructions. Any tissue from the middle section that remained following digestion, plus the unprocessed anterior and posterior sections of each larva have been stored with the original label in a screw-cap

neg: Organ pipe than a similar open pipe of the same length. Also, such an open pipe produces a tone in which both the even-numbered and the odd-numbered partials are present, while a stopped pipe, such as a gedackt, produces a tone with odd-numbered partials. The tone of a stopped pipe tends to be gentler and sweeter than that of an open pipe, though this is largely at the discretion of the voicer. The pitch produced by an organ pipe is determined in two fundamentally different ways. For a reed pipe it is determined mainly by the mechanical properties of the reed and

neg: Self-expandable metallic stent Self-expandable metallic stent A self-expandable metallic stent (or SEMS) is a metallic tube, or stent, used in order to hold open a structure in the gastrointestinal tract in order to allow the passage of food, chyme, stool, or other secretions required for digestion. SEMS are inserted by endoscopy, wherein a fibre optic camera is inserted either through the mouth or retrograde through the colon, in order to reach an area of narrowing. As such, it is termed an "endoprosthesis". SEMS can also be inserted using fluoroscopy where an X-ray image is used to guide insertion, or used as an adjunct

neg: Digestion small molecules the body can use. In the human digestive system, food enters the mouth and mechanical digestion of the food starts by the action of mastication (chewing), a form of mechanical digestion, and the wetting contact of saliva. Saliva, a liquid secreted by the salivary glands, contains salivary amylase, an enzyme which starts the digestion of starch in the food; the saliva also contains mucus, which lubricates the food, and hydrogen carbonate, which provides the ideal conditions of pH (alkaline) for amylase to work. After undergoing mastication and starch digestion, the food will be in the form of a

neg: Insulin resistance to diplomat” the insensitivity of skeletal muscle to insulin could divert the glucose to the brain, which doesn’t require insulin receptors. This has shown increased in cognitive development across various studies. Insulin resistance Insulin resistance (IR) is considered as a pathological condition in which cells fail to respond normally to the hormone insulin. To prevent hyperglycemia and noticeable organ damage over time, the body produces insulin when glucose starts to be released into the bloodstream, primarily from the digestion of carbohydrates in the diet. Under normal conditions of insulin reactivity, this insulin response triggers glucose being taken into body cells,

neg: Secretin discovered to play a role in osmoregulation by acting on the hypothalamus, pituitary gland, and kidney. Secretin was the first hormone to be identified. In 1902, William Bayliss and Ernest Starling were studying how the nervous system controls the process of digestion. It was known that the pancreas secreted digestive juices in response to the passage of food (chyme) through the pyloric sphincter into the duodenum. They discovered (by cutting all the nerves to the pancreas in their experimental animals) that this process was not, in fact, governed by the nervous system. They determined that a substance secreted by the

neg: Self-expandable metallic stent time, SEMS may also migrate to a different position that does not help with treatment of the obstructed area. This may be treated with placement of a second SEMS, or endoscopic attempts to reposition or remove the first. Rarely, SEMS may fracture or intussescept after endoscopic intervention. Self-expandable metallic stent A self-expandable metallic stent (or SEMS) is a metallic tube, or stent, used in order to hold open a structure in the gastrointestinal tract in order to allow the passage of food, chyme, stool, or other secretions required for digestion. SEMS are inserted by endoscopy, wherein a fibre optic camera

neg: Cholecystokinin the brain. It is released rapidly into the circulation in response to a meal. The greatest stimulator of CCK release is the presence of fatty acids and/or certain amino acids in the chyme entering the duodenum. In addition, release of CCK is stimulated by monitor peptide (released by pancreatic acinar cells), CCK-releasing protein (via paracrine signalling mediated by enterocytes in the gastric and intestinal mucosa), and acetylcholine (released by the parasympathetic nerve fibers of the vagus nerve). Once in the circulatory system, CCK has a relatively short half-life. CCK mediates digestion in the small intestine by inhibiting gastric emptying. It

neg: Anthidium manicatum recent mates tend to father the brood she produces. This phenomenon might be caused by a variety of mechanisms, including sperm digestion or removal by the female, removal by the next male, or stratification of sperm from different males in the sperm storage organ of the female (i.e. the last sperm in is the first to come out). Studies have shown that "A. manicatum" males that copulate late in a sequence have a greater than average chance of paternity of the female’s eggs. Late male sperm precedence may have fostered the evolution of resource defense in "A. manicatum" males. Unlike

neg: Extracellular digestion here the digestion is intracellular. Extracellular digestion Extracellular digestion is a process in which saprobionts feed by secreting enzymes through the cell membrane onto the food. The enzymes catalyze the digestion of the food into molecules small enough to be taken up by passive diffusion, transport, or phagocytosis. Since digestion occurs outside the cell, it is said to be extracellular. It takes place either in the lumen of the digestive system, in a gastric cavity or other digestive organ, or completely outside the body. The prefix "extra" means "outside", and indicates that extracellular digestion must occur outside the cell. During

neg: Extracellular digestion Extracellular digestion Extracellular digestion is a process in which saprobionts feed by secreting enzymes through the cell membrane onto the food. The enzymes catalyze the digestion of the food into molecules small enough to be taken up by passive diffusion, transport, or phagocytosis. Since digestion occurs outside the cell, it is said to be extracellular. It takes place either in the lumen of the digestive system, in a gastric cavity or other digestive organ, or completely outside the body. The prefix "extra" means "outside", and indicates that extracellular digestion must occur outside the cell. During extracellular digestion, food is broken

neg: Love dart the function of love darts in which the love dart is used by the male component to manipulate the female component’s sperm collection, increasing paternity. A closer look into the behavior of "Cornu aspersum", shows that it is not the mechanical action of the dart that increases paternity in sperm donors but instead the mucus that coats the dart. The mucus carries an that is transferred into the recipient snail’s hemolymph when the dart is stabbed. This allohormone reconfigures the female component of the reproductive system in the receiving individual: the bursa copulax (sperm digestion organ) is closed off, and

neg: Jasmonate feedback loop. These transcription factors all have different impacts on JAZ levels after JA signaling. JAZ levels in turn affect transcription factor and gene expression levels. In other words, on top of activating different response genes, the transcription factors can vary JAZ levels to achieve specificity in response to JA signals. Although jasmonate (JA) regulates many different processes in the plant, its role in wound response is best understood. Following mechanical wounding or herbivory, JA biosynthesis is rapidly activated, leading to expression of the appropriate response genes. For example, in the tomato, wounding produces defense molecules that inhibit leaf digestion

neg: Clonewheel organ Clonewheel organ "Clonewheel organ" is a musician jargon term used to refer to an electronic musical instrument that emulates (or "clones") the sound of the electromechanical tonewheel-based organs formerly manufactured by Hammond from the 1930s to the 1970s. Clonewheel organs generate sounds using solid-state circuitry or computer chips, rather than with heavy mechanical tonewheels, making clonewheel organs much lighter-weight and smaller than vintage Hammonds, and easier to transport to live performances and recording sessions. The phrase "clonewheel" is a pun on the term used to describe how the original Hammond produces sound: through "tonewheels". The first generation of clonewheel organs

neg: Richard Saumarez or common matter (chemistry) cannot be employed to any useful end in understanding living matter (physiology). As an example, the "assimilating and convertible power" or "converting power of the assimilating organ" found in digestion, as "proved by Mr. Hunter and Spallanzani" cannot be explained by chemical laws and actions, but must be performed by a "living power resident in the organ and its secretions, in this case, that of the gastric juice of animals and man." From all of his observations of the facts from previous experiments, Saumarez is led to the logical conclusion that "the process of digestion...is not

neg: Common octopus to tolerate a wide range of pH related to temperature. As a temperature conformer, "Octopus vulgaris" does not have any specific organ or structure dedicated to heat production or heat exchange. Like all animals they produce heat as a result of ordinary metabolic processes such as digestion of food, but take no special means to keep their body temperature within a certain range. Their preferred temperature directly reflects the temperature they are acclimated to. They have an acceptable ambient temperature range of 13–28 °C, with their optimum for maximum metabolic efficiency being about 20 °C. As ectothermal animals, "Octopus vulgaris"

neg: Anaerobic digestion dumped at sea, dumped in landfills, or burnt in incinerators. Pressure from environmentally related legislation on solid waste disposal methods in developed countries has increased the application of anaerobic digestion as a process for reducing waste volumes and generating useful byproducts. It may either be used to process the source-separated fraction of municipal waste or alternatively combined with mechanical sorting systems, to process residual mixed municipal waste. These facilities are called mechanical biological treatment plants. If the putrescible waste processed in anaerobic digesters were disposed of in a landfill, it would break down naturally and often anaerobically. In this case,

neg: BioBrick and "Xbal". This leaves both plasmids with 4 base pair (bp) overhangs at the 5’ and 3’ ends. The "EcoRI" sites will ligate since they are complementary to each other. The "Xbal" and "SpeI" sites will also ligate as the digestion produces compatible ends. Now, both the DNA parts are in one plasmid. The ligation produces an 8 base pair ‘scar’ site between the two BioBrick parts. Since the scar site is a hybrid of the "Xbal" and "SpeI" sites, it is not recognized by either restriction enzyme. The prefix and suffix sequences remain unchanged by this digestion and ligation

neg: Tipu's Tiger A mechanical link causes the man's left arm to rise and fall. This action alters the pitch of the 'wail pipe'. Another mechanism inside the tiger's head expels air through a single pipe with two tones. This produces a "regular grunting sound" simulating the roar of the tiger. Concealed behind a flap in the tiger's flank is the small ivory keyboard of a two-stop pipe organ in the tiger's body, allowing tunes to be played. The style of both shell and workings, and analysis of the metal content of the original brass pipes of the organ (many have been replaced),

neg: The Description of the Human Body soul. A sick or injured body does not do what we want or moves in ways we do not want. He believed the death of the body stopped it from being fit to bring about movement. This did not necessarily happen because the soul left the body. René Descartes believed the body could exist through mechanical means alone. This included digestion, blood circulation, muscle movement and some brain function. He felt we all know what the human body is like because animals have similar bodies and we have all seen them opened up. He saw the body as a machine.

neg: Anaerobic digestion an integrated waste management system, anaerobic digestion reduces the emission of landfill gas into the atmosphere. Anaerobic digesters can also be fed with purpose-grown energy crops, such as maize. Anaerobic digestion is widely used as a source of renewable energy. The process produces a biogas, consisting of methane, carbon dioxide, and traces of other ‘contaminant’ gases. This biogas can be used directly as fuel, in combined heat and power gas engines or upgraded to natural gas-quality biomethane. The nutrient-rich digestate also produced can be used as fertilizer. With the re-use of waste as a resource and new technological approaches that

neg: Anaerobic digestion sludge blanket digestion (UASB), hydraulic residence times can be as short as 1 hour to 1 day, and solid retention times can be up to 90 days. In this manner, a UASB system is able to separate solids and hydraulic retention times with the use of a sludge blanket. Continuous digesters have mechanical or hydraulic devices, depending on the level of solids in the material, to mix the contents, enabling the bacteria and the food to be in contact. They also allow excess material to be continuously extracted to maintain a reasonably constant volume within the digestion tanks. The anaerobic

neg: HomeBiogas anaerobic digestion is achieved by bacteria living inside the system. As a result, HomeBiogas runs without electricity. As of 2016, HomeBiogas can receive inputs of up to six liters per day of food waste, or up to 15 liters per day of animal manure. Each kilogram may produce 200 liters of biogas, enough fuel for an hour of cooking. Annually, each HomeBiogas system may eliminate up to one ton of organic waste, and six tons of carbon dioxide. HomeBiogas HomeBiogas is a biogas company based in Beit Yanai, Israel. The company produces and sells anaerobic digesters that convert organic waste

neg: Mechanical biological treatment advantageous for later transport and combustion. Some systems incorporate both anaerobic digestion and composting. This may either take the form of a full anaerobic digestion phase, followed by the maturation (composting) of the digestate. Alternatively a partial anaerobic digestion phase can be induced on water that is percolated through the raw waste, dissolving the readily available sugars, with the remaining material being sent to a windrow composting facility. By processing the biodegradable waste either by anaerobic digestion or by composting MBT technologies help to reduce the contribution of greenhouse gases to global warming. Usable wastes for this system: Possible products

neg: Digestion gizzard add enzymes to the thick paste, which helps chemically breakdown the organic matter. By peristalsis, the mixture is sent to the intestine where friendly bacteria continue chemical breakdown. This releases carbohydrates, protein, fat, and various vitamins and minerals for absorption into the body. In most vertebrates, digestion is a multistage process in the digestive system, starting from ingestion of raw materials, most often other organisms. Ingestion usually involves some type of mechanical and chemical processing. Digestion is separated into four steps: Underlying the process is muscle movement throughout the system through swallowing and peristalsis. Each step in digestion requires

neg: Music House Museum Theatre, a 1924 Wurlitzer Theatre organ, and a 97-key Amaryllis Mortier dance organ that is thirty feet wide and eighteen feet high. Music House Museum The Music House Museum has a collection of restored antique musical instruments, early radios, and recordings. It is housed in a 1909 dairy barn and a 1905 granary farmhouse, located between the communities of Acme and Williamsburg in Grand Traverse County of Northern Michigan. It was established in 1983 and is a result of a hobby by an architect and a mechanical engineer. David Stiffler (an architect) and Dean Junker (a mechanical engineer) started a

neg: Star-nosed mole deformation, its mechanism of transduction can be explained in a few steps: Although these summarized steps of mechanical transduction give a hint of how the star-nosed mole converts mechanical information into potential actions, the entire mechanism of transduction behind this intricate mechanoreceptor is still unknown and further studies are required. Despite the poorly developed eyes, star-nosed moles have an intricate system to detect prey and understand their environment. During exploration, the mole's star-like appendage produces brief touches which compress Eimer’s organ against objects or substrate. When foraging, moles search in random patterns of touches lasting 20–30 . Catania and colleagues

neg: Surgical staple table in cold ischemia condition for the donor organ and after native organ removal in the recipient. This is finalized to make as brief as possible the donor organ dangerous warm ischemia phase that can be contained in the couple of minutes or less necessary just to connect the device's ends and actioning the stapler. Although most surgical staples are made of titanium, stainless steel is more often used in some skin staples and clips. Titanium produces less reaction with the immune system and, being non-ferrous, does not interfere significantly with MRI scanners, although some imaging artifacts may result. Synthetic

neg: Himark BioGas Edmonton and Hairy Hill, Alberta. IMUS The Integrated Manure Utilization System "IMUS" is an anaerobic digestion technology that uses organic waste to produce biogas, which is used to produce electricity and heat. The "IMUS" system produces organic fertilizer and reusable water as bioproducts. Anaerobic digestion technologies improves the local environment and community health, and helps in disease control, through effective hazardous waste disposal; fertilizer production; disease destruction; pollution prevention; odor elimination; and landfill replacement. The model integrates the anaerobic digestion technology with other energy consuming system, such as Municipal Facilities, Farm Operations, Open Pen Feedlots, Food Processing, Ethanol Plants, and

neg: Mechanical organ some instruments are operated by a music roll. In the movie "The Great Race" (1965) Professor Fate, with bandaged thumbs, is shown pretending to play a mechanical organ. Mechanical organ A mechanical organ is an organ that is self-playing, rather than played by a musician. For example, the barrel organ is activated either by a person turning a crank, or by clockwork driven by weights or springs. Usually, mechanical organs are pipe organs although some instruments were built using reeds similar to those found in a harmonium. Since the 1950s, some instruments have been built using electronics to generate the

neg: Mechanical organ Mechanical organ A mechanical organ is an organ that is self-playing, rather than played by a musician. For example, the barrel organ is activated either by a person turning a crank, or by clockwork driven by weights or springs. Usually, mechanical organs are pipe organs although some instruments were built using reeds similar to those found in a harmonium. Since the 1950s, some instruments have been built using electronics to generate the sound, though still operated by mechanical or pneumatic means. From the 1990s pipe organs have been built that are operated by MIDI rather than the earlier mechanical means.

neg: Internal circulation reactor Internal circulation reactor The internal circulation reactor (IC reactor) is a form of anaerobic digester. It is primarily designed to treat wastewater. The IC reactor is an evolution of the UASB and EGSB digestion systems. The digester typically produces biogas with a high concentration methane (c80%). In essence the IC to improve digestion rates and gas yields. The foot print for the IC reactor is therefore typically smaller. However, it is taller due to the increased complexity of the reactor. The IC reactor typically comes as part of a two-stage anaerobic digestion system where it is preceded by an acidification

neg: Adagio and Allegro in F minor for a mechanical organ, K. 594 Deym. Adagio and Allegro in F minor for a mechanical organ, K. 594 Adagio and Allegro in F minor for a mechanical organ, K. 594, is a composition by Wolfgang Amadeus Mozart, completed in late 1790. The piece was commissioned by Count for use as a funeral mass to be played on a mechanical organ clock in the mausoleum for the recently deceased Generalfeldmarschall (Fieldmarshall) Ernst Gideon von Laudon, part of the "Müllersche Kunstgalerie", the wax art gallery and organ museum of "Joseph Müller" (which was the Count Deym's assumed name). This displayed a casket covered with glass, through which

neg: Adagio and Allegro in F minor for a mechanical organ, K. 594 Adagio and Allegro in F minor for a mechanical organ, K. 594 Adagio and Allegro in F minor for a mechanical organ, K. 594, is a composition by Wolfgang Amadeus Mozart, completed in late 1790. The piece was commissioned by Count for use as a funeral mass to be played on a mechanical organ clock in the mausoleum for the recently deceased Generalfeldmarschall (Fieldmarshall) Ernst Gideon von Laudon, part of the "Müllersche Kunstgalerie", the wax art gallery and organ museum of "Joseph Müller" (which was the Count Deym's assumed name). This displayed a casket covered with glass, through which one

neg: Mechanical biological treatment and has a lower impact than either MBT processes producing RDF for incineration or incineration of waste without MBT. Friends of the Earth does not support MBT plants that produce refuse derived fuel (RDF), and believes MBT processes should occur in small, localised treatment plants. Mechanical biological treatment A mechanical biological treatment system is a type of waste processing facility that combines a sorting facility with a form of biological treatment such as composting or anaerobic digestion. MBT plants are designed to process mixed household waste as well as commercial and industrial wastes. The terms "mechanical biological treatment" or "mechanical

neg: Muscle tissue musculature is found in(almost) all organ system such as hollow organs (e.g. stomach, bladder), in tubular structures (e.g. vessels, bile ducts), in sphincters, in the uterus, in the eye etc. In addition it plays an important role in the ducts of exocrine glands. It fulfills various tasks such as sealing orifices (e.g. pylorus, uterine os) or the transport of the chyme through wavelike contractions of the intestinal tube. On the one hand smooth muscle cells contract slower than skeletal muscle cells, on the other hand they are stronger, more sustained and require less energy. by Aatir Ejaz Cardiac muscle is

neg: Resource recovery and accelerate the natural process of decomposition of organic matter. There is a large variety of composting and digestion methods and technologies varying in complexity from simple home compost heaps, to small town scale batch digesters, industrial-scale enclosed-vessel digestion of mixed domestic waste (see mechanical biological treatment). Methods of biological decomposition are differentiated as being aerobic or anaerobic methods, though hybrids of the two methods also exist. Anaerobic digestion of the organic fraction of municipal solid waste (MSW) has been found to be more environmentally effective, than landfill, incineration or pyrolysis. Life cycle analysis (LCA) was used to compare different

neg: Fish anatomy higher vertebrates. The liver is a large vital organ present in all fish. It has a wide range of functions, including detoxification, protein synthesis, and production of biochemicals necessary for digestion. It is very susceptible to contamination by organic and inorganic compounds because they can accumulate over time and cause potentially life-threatening conditions. Because of the liver's capacity for detoxification and storage of harmful components, it is often used as an environmental biomarker. Fish have what is often described as a two-chambered heart, consisting of one atrium to receive blood and one ventricle to pump it, in contrast to three

neg: Westerkerk the old pipes and the wind chests were re used. In 1939, the keyboard was equipped with electric tracker action and even a swell work was added. It was not what this organ was intended to be in sound and action. The organ was almost doubled in size, but was also too big for its case. So between 1989 and 1992 the organ was reconstructed by Flentrop organ builders in Zaandam to its former mechanical action again more or less like Christiaan Vater made it in 1727. Today the 'bovenwerk' (Oberwerk, located in the top of the organ case) is

neg: Mechanical biological treatment Mechanical biological treatment A mechanical biological treatment system is a type of waste processing facility that combines a sorting facility with a form of biological treatment such as composting or anaerobic digestion. MBT plants are designed to process mixed household waste as well as commercial and industrial wastes. The terms "mechanical biological treatment" or "mechanical biological pre-treatment" relate to a group of solid waste treatment systems. These systems enable the recovery of materials contained within the mixed waste and facilitate the stabilisation of the biodegradable component of the material. The sorting component of the plants typically resemble a materials recovery

neg: Organ transplantation suffocation, etc.). Breathing is maintained via artificial sources, which, in turn, maintains heartbeat. Once brain death has been declared the person can be considered for organ donation. Criteria for brain death vary. Because less than 3% of all deaths in the U.S. are the result of brain death, the overwhelming majority of deaths are ineligible for organ donation, resulting in severe shortages. Organ donation is possible after cardiac death in some situations, primarily when the person is severely brain injured and not expected to survive without artificial breathing and mechanical support. Independent of any decision to donate, a person's next-of-kin

neg: Pseudomyxoma peritonei Pseudomyxoma peritonei Pseudomyxoma peritonei (PMP) is a clinical condition caused by cancerous cells (mucinous adenocarcinoma) that produce abundant mucin or gelatinous ascites. The tumors cause fibrosis of tissues and impede digestion or organ function, and if left untreated, the tumors and mucin they produce will fill the abdominal cavity. This will result in compression of organs and will destroy the function of colon, small intestine, stomach, or other organs. Prognosis with treatment in many cases is optimistic, but the disease is lethal if untreated, with death by cachexia, bowel obstruction, or other types of complications. This disease is most commonly

neg: G-force g-forces may be destructive. Gravitation acting alone does not produce a g-force, even though g-forces are expressed in multiples of the acceleration of a standard gravity. Thus, the standard gravitational acceleration at the Earth's surface produces g-force only indirectly, as a result of resistance to it by mechanical forces. These mechanical forces actually produce the g-force acceleration on a mass. For example, the 1 g force on an object sitting on the Earth's surface is caused by mechanical force exerted in the upward direction by the ground, keeping the object from going into free fall. The upward contact force from

neg: Reactive hypoglycemia a plasma glucose level eventually much lower than the baseline level. Sugar crashes are not to be confused with the after-effects of consuming large amounts of "protein", which produces fatigue akin to a sugar crash, but are instead the result of the body prioritising the digestion of ingested food. The prevalence of this condition is difficult to ascertain because a number of stricter or looser definitions have been used. It is recommended that the term reactive hypoglycemia be reserved for the pattern of postprandial hypoglycemia which meets the Whipple criteria (symptoms correspond to measurably low glucose and are relieved by

neg: Organ console of an organ can be played simultaneously from one manual. On a mechanical-action organ, a coupler may connect one division's manual directly to the other, actually moving the keys of the first manual when the second is played. Some organs feature a device to add the octave above or below what is being played by the fingers. The "super-octave" adds the octave above, the "sub-octave" the octave below. These may be attached to one division only, for example "Swell octave" (the "super" is often assumed), or they may act as a coupler, for example "Swell octave to Great" which gives

neg: C. B. Fisk the world. The third, known as Opus 142, is a three-manual, six-stop, practice organ installed in 2012 in the Music Addition practice facilities. The workshop attracted young co-workers who combined their talents in music, art, engineering, and cabinet making to build organs that redefined modern American organ building. Always experimenting, C. B. Fisk was the first modern American organ builder to abandon the electro-pneumatic action of the early twentieth century and return to the mechanical (tracker) key and stop action of historical European and early American instruments. The Fisk firm went on to construct what were at the time the

neg: Basal metabolic rate an intake of oxygen along with coenzymes to provide energy for survival (usually from macronutrients like carbohydrates, fats, and proteins) and expel carbon dioxide, due to processing by the Krebs cycle. For the BMR, most of the energy is consumed in maintaining fluid levels in tissues through osmoregulation, and only about one-tenth is consumed for mechanical work, such as digestion, heartbeat, and breathing. What enables the Krebs cycle to perform metabolic changes to fats, carbohydrates, and proteins is energy, which can be defined as the ability or capacity to do work. The breakdown of large molecules into smaller molecules—associated with

neg: Renewable energy in Scotland have lower net carbon emissions than other production techniques. Biogas, or landfill gas, is a biofuel produced through the intermediary stage of anaerobic digestion consisting mainly of 45–90% biologically produced methane and carbon dioxide. In early 2007 a thermophilic anaerobic digestion facility was commissioned in Stornoway in the Western Isles. The Scottish Environment Protection Agency (SEPA) and the Renewable Energy Association are also leading the way towards the establishment of a digestate standard to facilitate the use of solid outputs from digesters on land. Anaerobic digestion and mechanical biological treatment facilities have been planned at a number of other locations

neg: Whistle Whistle A whistle is an instrument which produces sound from a stream of gas, most commonly air. It may be mouth-operated, or powered by air pressure, steam, or other means. Whistles vary in size from a small slide whistle or nose flute type to a large multi-piped church organ. Whistles have been around since early humans first carved out a gourd or branch and found they could make sound with it. In prehistoric Egypt, small shells were used as whistles. Many present day wind instruments are inheritors of these early whistles. With the rise of more mechanical power, other forms

neg: Gastrovascular cavity Gastrovascular cavity The gastrovascular cavity is the primary organ of digestion and circulation in two major animal phyla: the Cnidaria (including jellyfish and corals) and Platyhelminthes (flatworms). The cavity may be extensively branched into a system of canals. In cnidarians, the gastrovascular system is also known as the coelenteron, and is commonly known as a "blind gut" or "blind sac", since food enters and waste exits through the same orifice. The radially symmetrical cnidarians have a sac-like body in two distinct layers, the epidermis and gastrodermis, with a jellylike layer called the mesoglea between. Extracellular digestion takes place within the

neg: Gastrointestinal wall all this in place are the mesenteries which suspend the intestine in the abdominal cavity and stop it being disturbed when a person is physically active. The gastrointestinal tract has a form of general histology with some differences that reflect the specialization in functional anatomy. The mucosa is the innermost layer of the gastrointestinal tract. It surrounds the lumen of the tract, and comes into direct contact with digested food (chyme). The mucosa itself is made up of three layers: The mucosae are highly specialized in each organ of the gastrointestinal tract to deal with the different conditions. The most

neg: Sewage sludge treatment accomplished through heating during thermophilic digestion, composting, or incineration. The choice of a sludge treatment method depends on the volume of sludge generated, and comparison of treatment costs required for available disposal options. Air-drying and composting may be attractive to rural communities, while limited land availability may make aerobic digestion and mechanical dewatering preferable for cities, and economies of scale may encourage energy recovery alternatives in metropolitan areas. Energy may be recovered from sludge through methane gas production during anaerobic digestion or through incineration of dried sludge, but energy yield is often insufficient to evaporate sludge water content or to

neg: Gastrointestinal tract gut. The blood vessels supplying these structures remain constant throughout development. The gastrointestinal tract has a form of general histology with some differences that reflect the specialization in functional anatomy. The GI tract can be divided into four concentric layers in the following order: The mucosa is the innermost layer of the gastrointestinal tract. The mucosa surrounds the lumen, or open space within the tube. This layer comes in direct contact with digested food (chyme). The mucosa is made up of: The mucosae are highly specialized in each organ of the gastrointestinal tract to deal with the different conditions. The

neg: Organ (music) of the pipes can be replaced. Non-piped organs include the reed organ or harmonium, which like the accordion and harmonica (or "mouth organ") use air to excite free reeds. Electronic organs or digital organs, notably the Hammond organ, generate electronically produced sound through one or more loudspeakers. Mechanical organs include the barrel organ, water organ, and Orchestrion. These are controlled by mechanical means such as pinned barrels or book music. Little barrel organs dispense with the hands of an organist and bigger organs are powered in most cases by an organ grinder or today by other means such as an

neg: Street organ attract attention, as well as the important task of collecting money from passers-by. In an article from 1929, George Orwell wrote of the organ-grinders of London: "To ask outright for money is a crime, yet it is perfectly legal to annoy one's fellow citizens by pretending to entertain them. Their dreadful music is the result of a purely mechanical gesture, and is only intended to keep them on the right side of the law. There are in London around a dozen firms specialising in the manufacture of piano organs, which they hire out for 15 shillings a week. The poor

neg: Cellular adaptation include skeletal muscle, cardiac muscle, secondary sex organs, and the brain. Hypertrophy is an increase in cell size. If enough cells of an organ hypertrophy so will the whole organ. The heart and kidneys have increased susceptibility to hypertrophy. Hypertrophy involves an increase in intracellular protein rather than cytosol (intracellular fluid). Hypertrophy may be caused by mechanical signals (e.g., stretch) or trophic signals (e.g., growth factors). An example of physiologic hypertrophy is in skeletal muscle with sustained weight bearing exercise. An example of pathologic hypertrophy is in cardiac muscle as a result of hypertension. Hyperplasia is an increase in the

neg: Digestate Digestate Digestate is the material remaining after the anaerobic digestion of a biodegradable feedstock. Anaerobic digestion produces two main products: digestate and biogas. Digestate is produced both by acidogenesis and methanogenesis and each has different characteristics. Acidogenic digestate is fibrous and consists of structural plant matter including lignin and cellulose. Acidogenic digestate has high moisture retention properties. The digestate may also contain minerals and remnants of bacteria. Methanogenic digestate is a sludge (sometimes called a liquor). This is often high in nutrients such as ammoniums and phosphates. The primary use of digestate is as a soil conditioner. Acidogenic digestate provides

neg: Mechanical heat treatment Mechanical heat treatment Mechanical heat treatment (MHT) is an alternative waste treatment technology. This technology is also commonly termed autoclaving. MHT involves a mechanical sorting or pre-processing stage with technology often found in a material recovery facility. The mechanical sorting stage is followed by a form of thermal treatment. This might be in the form of a waste autoclave or processing stage to produce a refuse derived fuel pellet. MHT is sometimes grouped along with mechanical biological treatment. MHT does not however include a stage of biological degradation (anaerobic digestion or composting). Different MHT systems may be configured to meet

neg: Sound recording and reproduction also invented an automatic flute player, which appears to have been the first programmable machine. In the 14th century, a mechanical bell-ringer controlled by a rotating cylinder was introduced in Flanders. Similar designs appeared in barrel organs (15th century), musical clocks (1598), barrel pianos (1805), and music boxes (ca. 1800). A music box is an automatic musical instrument that produces sounds by the use of a set of pins placed on a revolving cylinder or disc so as to pluck the tuned teeth (or "lamellae") of a steel comb. The fairground organ, developed in 1892, used a system of accordion-folded

neg: Brown Dog affair in London. The men knew that the pancreas produces digestive juices in response to increased acidity in the duodenum and jejunum, because of the arrival of chyme there. By severing the duodenal and jejunal nerves in anaesthetized dogs, while leaving the blood vessels intact, then introducing acid into the duodenum and jejunum, they discovered that the process is not mediated by a nervous response, but by a new type of chemical reflex. They named the chemical messenger secretin, because it is secreted by the intestinal lining into the bloodstream, stimulating the pancreas on circulation. In 1905 Starling coined the term

neg: St. Mary's Church, Lübeck built by Johann Friedrich Schulze, in the spirit of the time, with four manuals, a pedalboard, and 80 voices, behind the historic organ case by Benedikt Dreyer, which was restored and added to by Carl Julius Milde. This great organ was destroyed in 1942 and was replaced in 1968 by what was then the largest mechanical-action organ in the world. It was built by Kemper & Son. It has 5 manuals and a pedalboard, 100 stops and 8,512 pipes; the longest are , the smallest is the size of a cigarette. The tracker action operates electrically and has free combinations;