query: the brain region that controls most autonomic responses is the

pos: Autonomic nervous system center), vasomotor activity (the vasomotor center), and certain reflex actions such as coughing, sneezing, swallowing and vomiting. Those are then subdivided into other areas and are also linked to ANS subsystems and nervous systems external to the brain. The hypothalamus, just above the brain stem, acts as an integrator for autonomic functions, receiving ANS regulatory input from the limbic system to do so. The autonomic nervous system has three branches: the sympathetic nervous system, the parasympathetic nervous system and the enteric nervous system. Some textbooks do not include the enteric nervous system as part of this system. The sympathetic nervous

pos: Neuroglycopenia lactic acid, ketones). Knowledge of the "switchover" process is incomplete. The most severe neuroglycopenic symptoms occur with hypoglycemia caused by excess insulin because insulin reduces the availability of other fuels by suppressing ketogenesis and gluconeogenesis. A few types of specialized neurons, especially in the hypothalamus, act as glucose sensors, responding to changing levels of glucose by increasing or decreasing their firing rates. They can elicit a variety of hormonal, autonomic, and behavioral responses to neuroglycopenia. The hormonal and autonomic responses include release of counterregulatory hormones. There is some evidence that the autonomic nervous system can alter liver glucose metabolism independently

pos: Neuroendocrine cell peptides are GRP, the mammalian form of bombesin, and CGRP; these substances exert direct mitogenic effects on epithelial cells and exhibit many properties akin to growth factors. Specialized groups of neuroendocrine cells can be found at the base of the third ventricle in the brain (in a region called the hypothalamus). This area controls most anterior pituitary cells and thereby regulates functions in the entire body, like responses to stress, cold, sleep, and the reproductive system. The neurons send processes to a region connecting to the pituitary stalk and releasing hormones are delivered into the bloodstream. They are carried by

pos: Nervous system network models The second phase is limbic or paleo-mammalian brain and performs the four functions needed for animal survival – fighting, feeding, fleeing, and fornicating. The third phase is the neocortex or the neo-mammalian brain. The higher cognitive functions which distinguish humans from other animals are primarily in the cortex. The reptilian brain controls muscles, balance, and autonomic functions, such as breathing and heartbeat. This part of the brain is active, even in deep sleep. The limbic system includes the hypothalamus, hippocampus, and amygdala. The neocortex includes the cortex and the cerebrum. It corresponds to the brain of primates and, specifically, the

pos: Central nucleus of the amygdala Central nucleus of the amygdala The central nucleus of the amygdala (CeA or aCeN) is a nucleus within the amygdala. It "serves as the major output nucleus of the amygdala and participates in receiving and processing pain information." CeA "connects with brainstem areas that control the expression of innate behaviors and associated physiological responses." CeA has dopaminergic projections. CeA is responsible for "autonomic components of emotions (e.g., changes in heart rate, blood pressure, and respiration) primarily through output pathways to the lateral hypothalamus and brain stem." The CeA is also responsible for "conscious perception of emotion primarily through the ventral

pos: Human brain sleep deprivation show the absolute need for sleep. The lateral hypothalamus contains orexinergic neurons that control appetite and arousal through their projections to the ascending reticular activating system. The hypothalamus controls the pituitary gland through the release of peptides such as oxytocin, and vasopressin, as well as dopamine into the median eminence. Through the autonomic projections, the hypothalamus is involved in regulating functions such as blood pressure, heart rate, breathing, sweating, and other homeostatic mechanisms. The hypothalamus also plays a role in thermal regulation, and when stimulated by the immune system, is capable of generating a fever. The hypothalamus is

pos: Autonomic nervous system or elderly. Autonomic nervous system The autonomic nervous system (ANS), formerly the vegetative nervous system, is a division of the peripheral nervous system that supplies smooth muscle and glands, and thus influences the function of internal organs. The autonomic nervous system is a control system that acts largely unconsciously and regulates bodily functions such as the heart rate, digestion, respiratory rate, pupillary response, urination, and sexual arousal. This system is the primary mechanism in control of the fight-or-flight response. Within the brain, the autonomic nervous system is regulated by the hypothalamus. Autonomic functions include control of respiration, cardiac regulation (the

pos: Autonomic nervous system Autonomic nervous system The autonomic nervous system (ANS), formerly the vegetative nervous system, is a division of the peripheral nervous system that supplies smooth muscle and glands, and thus influences the function of internal organs. The autonomic nervous system is a control system that acts largely unconsciously and regulates bodily functions such as the heart rate, digestion, respiratory rate, pupillary response, urination, and sexual arousal. This system is the primary mechanism in control of the fight-or-flight response. Within the brain, the autonomic nervous system is regulated by the hypothalamus. Autonomic functions include control of respiration, cardiac regulation (the cardiac control

pos: Hypothalamus of the autonomic nervous system. It synthesizes and secretes certain neurohormones, called releasing hormones or hypothalamic hormones, and these in turn stimulate or inhibit the secretion of hormones from the pituitary gland. The hypothalamus controls body temperature, hunger, important aspects of parenting and attachment behaviours, thirst, fatigue, sleep, and circadian rhythms. The hypothalamus derives its name from Greek ὑπό, "under" and θάλαμος, thalamus. The hypothalamus is a brain structure made up of distinct nuclei as well as less anatomically distinct areas. It is found in all vertebrate nervous systems. In mammals, magnocellular neurosecretory cells in the paraventricular nucleus and the

neg: Reflex arc Reflex arc A reflex arc is a neural pathway that controls a reflex. In vertebrates, most sensory neurons do not pass directly into the brain, but synapse in the spinal cord. This allows for faster reflex actions to occur by activating spinal motor neurons without the delay of routing signals through the brain. However, the brain will receive the sensory input while the reflex is being carried out and the analysis of the signal takes place after the reflex action. There are two types: autonomic reflex arc (affecting inner organs) and somatic reflex arc (affecting muscles). However, autonomic reflexes sometimes

neg: Peripheral nervous system plexus brachialis, a tangled array of nerves, splitting, combining and recombining, to form the nerves that subserve the upper-limb and upper back. Although the brachial plexus may appear tangled, it is highly organized and predictable, with little variation between people. See brachial plexus injuries. The anterior divisions of the lumbar nerves, sacral nerves, and coccygeal nerve form the lumbosacral plexus, the first lumbar nerve being frequently joined by a branch from the twelfth thoracic. For descriptive purposes this plexus is usually divided into three parts: The autonomic nervous system controls involuntary responses to regulate physiological functions. The brain and spinal

neg: Affective neuroscience The Right hemisphere has been linked with mental strategies that are nonverbal, synthetic, integrative, holistic, and Gestalt which makes it ideal for processing emotion. The right hemisphere is more in touch with subcortical systems of autonomic arousal and attention as demonstrated in patients that have increased spatial neglect when damage is associated to the right brain as opposed to the left brain. Right hemisphere pathologies have also been linked with abnormal patterns of autonomic nervous system responses. These findings would help signify the relationship of the subcortical brain regions to the right hemisphere as having a strong connection. The valence

neg: Optic tract retinal fibers from the left eye form the right optic tract. Several autonomic ocular motor responses are consensual. The optic tract is primarily responsible for relaying visual information to the LGN, but it is also peripherally responsible for transducing these bilateral autonomic reflexes, including the pupillary light reflex and pupillary dark reflex. The pupillary light reflex is an autonomic reflex that controls pupil diameter to accommodate for increases in illumination as perceived by the retina. Higher light intensity causes pupil constriction, and the increase of light stimulation of one eye will cause pupillary constriction of both eyes. The neural circuitry

neg: Vagovagal reflex Vagovagal reflex Vagovagal reflex refers to gastrointestinal tract reflex circuits where afferent and efferent fibers of the vagus nerve coordinate responses to gut stimuli via the dorsal vagal complex in the brain. The vagovagal reflex controls contraction of the gastrointestinal muscle layers in response to distension of the tract by food. This reflex also allows for the accommodation of large amounts of food in the gastrointestinal tracts. The vagus nerve, composed of both sensory afferents and parasympathetic efferents, carries signals from stretch receptors, osmoreceptors, and chemoreceptors to dorsal vagal complex where the signal may be further transmitted to autonomic centers

neg: Hyperreflexia a later stage of recovery because during the early stages they present with spinal shock. Reflex and motor recovery can sometimes return simultaneously. Hyperreflexia Hyperreflexia (or hyper-reflexia) is defined as overactive or overresponsive reflexes. Examples of this can include twitching or spastic tendencies, which are indicative of upper motor neuron disease as well as the lessening or loss of control ordinarily exerted by higher brain centers of lower neural pathways (disinhibition). See Autonomic dysreflexia. The most common cause of hyperreflexia is spinal cord injury (see autonomic dysreflexia). Standard stimuli like the filling of the bladder can cause excessive responses from

neg: Hyperreflexia Hyperreflexia Hyperreflexia (or hyper-reflexia) is defined as overactive or overresponsive reflexes. Examples of this can include twitching or spastic tendencies, which are indicative of upper motor neuron disease as well as the lessening or loss of control ordinarily exerted by higher brain centers of lower neural pathways (disinhibition). See Autonomic dysreflexia. The most common cause of hyperreflexia is spinal cord injury (see autonomic dysreflexia). Standard stimuli like the filling of the bladder can cause excessive responses from the nervous system, such causes are not known. But "hyperreflexia" can be developed via many other causes, including medication and stimulant side effects,

neg: Psychoneuroimmunology the immune responses to innocuous antigens triggers an increase in the activity of hypothalamic neurons and hormonal and autonomic nerve responses that are relevant for immunoregulation and are integrated at brain levels (see review). On these bases, they proposed that the immune system acts as a sensorial receptor organ that, besides its peripheral effects, can communicate to the brain and associated neuro-endocrine structures its state of activity. These investigators also identified products from immune cells, later characterized as cytokines, that mediate this immune-brain communication (more references in ). In 1981, David L. Felten, then working at the Indiana University School

neg: Classification of peripheral nerves 1920s, these divisions have remained relatively constant; the parasympathetic nervous system is known to regulate unconscious activities of the body and maintain homeostasis, the sympathetic nervous system controls responses to external stimuli, but both are involuntary functions. Langley also described an enteric nervous system although it has received minimal attention, and most modern textbooks tend to only mention the sympathetic and parasympathetic pathways in the context of the autonomic nervous system. The nerve classifications of the autonomic nervous system created by the traditional methodologies have remained mostly unchanged over the last 100 years. However, modern perspectives have placed more of

neg: Muscarine These receptors were named after muscarine. There are 5 different types of muscarinic receptors; M - M, and most tissues express a mixture of subtypes. The M and M subtypes mediate muscarinic responses at peripheral autonomic tissues. M and M subtypes are more abundant in brain and autonomic ganglia. M, M and M interact with G proteins to stimulate phosphoinositide hydrolysis and the release of intracellular calcium. M and M receptors interact with G proteins to inhibit adenylyl cyclase, which results in a decrease of intracellular concentration of cyclic adenosine monophosphate (cAMP). Most agonists for muscarine receptors are not selective

neg: Peripheral neuropathy have connections with the spinal cord and ultimately the brain, however. Most commonly autonomic neuropathy is seen in persons with long-standing diabetes mellitus type 1 and 2. In most—but not all—cases, autonomic neuropathy occurs alongside other forms of neuropathy, such as sensory neuropathy. Autonomic neuropathy is one cause of malfunction of the autonomic nervous system, but not the only one; some conditions affecting the brain or spinal cord also may cause autonomic dysfunction, such as multiple system atrophy, and therefore, may cause similar symptoms to autonomic neuropathy. The signs and symptoms of autonomic neuropathy include the following: Neuritis is a

neg: Papez circuit causes high levels of aggression. He noticed that this heightened aggression correlated with damage to the hippocampus. Theoretically, this made sense to Papez who asserted that the hippocampus is responsible for the expression of emotion because of its connection to the autonomic nervous system. He also noticed that in other cases, certain stimuli (taste, smell, pain, etc.) would cause strong emotional responses. These stimuli activated not only the hippocampus but also other brain structures. He theorized that these brain structures worked together as the emotional control center in the brain and consequently founded the Papez circuit. Because of these studies,

neg: Psychic numbing they considers sustained aversive material and how the brain reacts in a habitual manner in an effort to remove the underlying emotional content. Cortisol helps regulate the stress response via the negative feedback loop, which are activated when a person is subjected to specific situations that trigger the relationship between the emotionally charged memories of the traumatic event and the observable autonomic responses. Stress can also be considered a brain-body reaction due to external or internal cues this can include the environment as well as memory. The areas of the brain that communicate with one another are the prefrontal cortex,

neg: Nociception In some conditions, excitation of pain fibers becomes greater as the pain stimulus continues, leading to a condition called hyperalgesia. The gate control theory of pain, proposed by Patrick David Wall and Ronald Melzack, postulates that nociception (pain) is "gated" by non-nociception stimuli such as vibration. Thus, rubbing a bumped knee seems to relieve pain by preventing its transmission to the brain. Pain is also "gated" by signals that descend from the brain to the spinal cord to suppress (and in other cases enhance) incoming nociception (pain) information. Nociception can also cause generalized autonomic responses before or without reaching consciousness

neg: Delirium tremens allosteric modulators at GABA receptors, the brain, in its desire to equalize an unbalanced chemical system, triggers the abrupt stopping of the production of endogenous GABA. This decrease becomes more and more marked as the addiction becomes stronger and as higher doses are needed to cause intoxication. In addition to having sedative properties, GABA is an immensely important regulatory neurotransmitter that controls the heart rate, blood pressure, and seizure threshold among myriad other important autonomic nervous subsystems. Delirium tremens is most common in people who have a history of alcohol withdrawal, especially in those who drink the equivalent of of

neg: Aorta blood vessels called vasa vasorum, which feed the tunica externa and tunica media outer layers of the aorta. The aortic arch contains baroreceptors and chemoreceptors that relay information concerning blood pressure and blood pH and carbon dioxide levels to the medulla oblongata of the brain. This information is processed by the brain and the autonomic nervous system mediates the homeostatic responses. Within the tunica media, smooth muscle and the extracellular matrix are quantitatively the largest components of the aortic vascular wall. The fundamental unit of the aorta is the elastic lamella, which consists of smooth muscle and elastic matrix. The

neg: Acute stress reaction stimuli. Hans Selye was the first to coin the term “general adaptation syndrome”, to suggest that stress induced physiological responses proceed through the stages of alarm, resistance, and exhaustion. The sympathetic branch of the autonomic nervous system gives rise to a specific set of physiological responses in response to physical or psychological stress. The body’s response to stress is also termed “fight-or-flight response”, and it is characterized by an increase in blood flow to skeletal muscles, the heart and brain, a rise in heart rate and blood pressure, as well as dilation of pupils, and an increase in the amount

neg: Anatomy found in groups and send messages along neural networks to other parts of the organism. Neurons can be connected together in ganglia. In higher animals, specialized receptors are the basis of sense organs and there is a central nervous system (brain and spinal cord) and a peripheral nervous system. The latter consists of sensory nerves that transmit information from sense organs and motor nerves that influence target organs. The peripheral nervous system is divided into the somatic nervous system which conveys sensation and controls voluntary muscle, and the autonomic nervous system which involuntarily controls smooth muscle, certain glands and internal

neg: James–Lange theory act model of emotion, a person must make meaning of the physical response based on context, prior experience, and social cues, before they know what emotion is attached to the situation. Barrett and James Gross have reviewed a variety of alternative models to James's theory of emotion. A study in 2009 found that patients who had lesions to the ventromedial prefrontal cortex had impaired emotional experiences, but unaffected autonomic responses while patients with lesions to the right somatosensory cortex had impaired autonomic responses without affected emotional experiences. This argued that autonomic responses were dissociated with emotional experiences. The researchers argued

neg: Julius Thomas Fraser change, so too does time change. In the humanistic sense, it is the perception of time that has changed, as humans have biologically evolved with different concepts of the world to those of our ancestral species. This biological evolution, and the different perceptions of time that it implies, are played out in every moment in our brain. Our brain functions in one sense as a unitary organ, but evolutionarily it contains different brains: one that controls autonomic function, one that perceives the world in the moment, and one that understands the world intellectually. By this understanding, the biological self that

neg: Emotionality inferiority. In early psychology, it was believed that passion (emotion) was a part of the soul inherited from the animals and that it must be controlled. identified that in the Romantic movement of the eighteenth and nineteenth centuries, reason and emotion were thought to be opposites. Physiological responses to emotion originate in the central nervous system, the autonomic nervous system, and the endocrine system. Some of the responses include: heart rate, sweating, rate and depth of respiration, and electrical activity in the brain. Many researchers have attempted to find a connection between specific emotions and a corresponding pattern of physiological

neg: Area postrema been closely linked to other autonomic functions such as regulation of food intake, body fluid homeostasis, and cardiovascular regulation through behavioral studies and electrophysiological studies. In 2007 in Japan, research was performed on the mechanism of excitability of area postrema neurons by extracellular ATP. Voltage clamp whole-cell recording techniques were used on rat brain slices. The results showed that most responses to ATP are excitatory and that they are mediated by particular P2 purinoceptors found in the area postrema. The role of the area postrema in flavor-conditioned aversion and preference was studied in 2001 by researchers at the Brooklyn College

neg: Autonomic neuropathy 2. In most—but not all—cases, autonomic neuropathy occurs alongside other forms of neuropathy, such as sensory neuropathy. Autonomic neuropathy is one cause of malfunction of the autonomic nervous system (referred to as dysautonomia), but not the only one; some conditions affecting the brain or spinal cord also may cause autonomic dysfunction, such as multiple system atrophy, and therefore, may cause similar symptoms to autonomic neuropathy. The signs and symptoms of autonomic neuropathy include the following: Many health conditions can cause autonomic neuropathy. Some common causes of autonomic neuropathy include: Autonomic neuropathy Autonomic neuropathy (also AN or AAN) is a form

neg: Autonomic neuropathy Autonomic neuropathy Autonomic neuropathy (also AN or AAN) is a form of polyneuropathy that affects the non-voluntary, non-sensory nervous system (i.e., the autonomic nervous system), affecting mostly the internal organs such as the bladder muscles, the cardiovascular system, the digestive tract, and the genital organs. These nerves are not under a person's conscious control and function automatically. Autonomic nerve fibers form large collections in the thorax, abdomen, and pelvis outside the spinal cord. They have connections with the spinal cord and ultimately the brain, however. Most commonly autonomic neuropathy is seen in persons with long-standing diabetes mellitus type 1 and

neg: Causes of transsexuality by Zhou "et al." (1995) found that in a region of the brain called the bed nucleus of the stria terminalis (BSTc), a region which is known for sex and anxiety responses (and which is affected by prenatal androgens), cadavers of six persons who were described as having been male-to-female transsexual or transgender persons in life had female-normal BSTc size, similar to the study's cadavers of cisgender women. While the transsexuals studied had taken hormones, this was accounted for by including cadavers of non-transsexual male and female controls who, for a variety of medical reasons, had experienced hormone reversal. The

neg: Dysautonomia better predictivity for anxiety disorders, while the Beck anxiety inventory may misleadingly suggest anxiety for patients with dysautonomia. The autonomic nervous system is a component of the peripheral nervous system and comprises two branches: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PSNS). The SNS controls the more active responses such as increasing heart rate and blood pressure. The PSNS slows down the heart rate and aids in digestion, for example. Symptoms typically arise from abnormal responses of either the sympathetic or parasympathetic systems based on situation or environment. The diagnosis of dysautonomia depends on the overall function

neg: Area postrema Area postrema The area postrema is a medullary structure in the brain that controls vomiting. Its privileged location in the brain also allows the area postrema to play a vital role in the control of autonomic functions by the central nervous system. It is one of the circumventricular organs, enabling the dual role of being a sensor for circulating chemical messengers in the blood, as well as integrating neural inputs in the brainstem. The area postrema is a small protuberance found at the inferoposterior limit of the fourth ventricle. Specialized ependymal cells are found within the area postrema. These specialized

neg: Stephen Porges social behavior. Foremost, the polyvagal perspective emphasizes the importance of phylogenetic changes in the neural structures regulating the heart and phylogenetic shifts providing insight into the adaptive function of both physiology and behavior. The theory emphasizes the phylogenetic emergence of two vagal systems: a potentially lethal ancient brain and cord circuits involved in defensive strategies of immobilization (e.g., fainting, freeze, fight) including dissociative states. Polyvagal responses provided a new conceptualization of the autonomic nervous system that emphasize neurophysiological mechanisms and phylogenetic shifts in the neural regulation of the psychological responses from the cranial nerves to the spine, spinal cord and

neg: Self-harm by it, such as specific time intervals between acts of self-harm, can also create a behavioural pattern that can result in a wanting or craving to fulfill thoughts of self-harm. Emotional pain activates the same regions of the brain as physical pain, so emotional stress can be a significantly intolerable state for some people. Some of this is environmental and some of this is due to physiological differences in responding. The autonomic nervous system is composed of two components: the sympathetic nervous system controls arousal and physical activation (e.g., the fight-or-flight response) and the parasympathetic nervous system controls physical processes

neg: Confabulation also result in confabulation. Research has shown that patients with damage to the inferior medial frontal lobe confabulate significantly more than patients with damage to the posterior area and healthy controls. This suggests that this region is key in producing confabulatory responses, and that memory deficit is important but not necessary in confabulation. Additionally, research suggests that confabulation can be seen in patients with frontal lobe syndrome, which involves an insult to the frontal lobe as a result of disease or traumatic brain injury (TBI). Finally, rupture of the anterior or posterior communicating artery, subarachnoid hemorrhage, and encephalitis are also

neg: Central nervous system effects from radiation exposure during spaceflight compared to controls. Those that were irradiated were adversely affected as reflected through the levels of dichlorofluorescein, heat shock, and synaptic proteins (for example, synaptobrevin and synaptophysin). Changes in these factors consequently altered cellular signaling (for example, calciumdependent protein kinase C and protein kinase A). These changes in brain responses significantly correlated with working memory errors in the radial maze. The results show differential brain-region-specific sensitivity induced by 56Fe irradiation ([figure 6-6]). These findings are similar to those seen in aged rats, suggesting that increased oxidative stress and inflammation may be responsible for the induction of both radiation and age-related

neg: Human brain able to describe it verbally, but when the picture is shown on the left, are unable to describe it, but may be able to give an indication with the left hand of the nature of the object shown. Emotions are generally defined as two-step multicomponent processes involving elicitation, followed by psychological feelings, appraisal, expression, autonomic responses, and action tendencies. Attempts to localize basic emotions to certain brain regions have been controversial, with some research finding no evidence for specific locations corresponding to emotions, and instead circuitry involved in general emotional processes. The amygdala, orbitofrontal cortex, mid and anterior insula cortex

neg: Disgust in the emotion of disgust. The insula has been shown by several studies to be the main neural correlate of the feeling of disgust both in humans and in macaque monkeys. The insula is activated by unpleasant tastes, smells, and the visual recognition of disgust in conspecific organisms. The anterior insula is an olfactory and gustatory center that controls visceral sensations and the related autonomic responses. It also receives visual information from the anterior portion of the ventral superior temporal cortex, where cells have been found to respond to the sight of faces. The posterior insula is characterized by connections

neg: Cannabinoid receptor antagonist memory, anxiety, control of appetite, emesis, motor behavior, sensory, autonomic and neuroendocrine responses, immune responses and inflammatory effects. There are two well-characterized endocannabinoids located in the brain and periphery. The first identified was anandamide (arachidonoyl ethanolamide) and the second was 2-AG (2-arachidonoyl glycerol). Additional endocannabinoids include virodhamine (O-arachidonoyl ethanolamine), noladin ether (2-arachidonoyl glyceryl ether) and NADA (N-arachidonoyl dopamine). CB receptors are coupled through G proteins and inhibit adenylyl cyclase and activate mitogen-activated protein (MAP) kinase. In addition, CB receptors inhibit presynaptic N- and P/Q-type calcium channels and activate inwardly rectifying potassium channels. CB antagonists produce inverse cannabimimetic effects that are

neg: Harlequin syndrome Harlequin syndrome Harlequin syndrome is a condition characterized by asymmetric sweating and flushing on the upper thoracic region of the chest, neck and face. Harlequin syndrome is considered an injury to the autonomic nervous system (ANS). The ANS controls some of the body's natural processes such as sweating, skin flushing and pupil response to stimuli. Such individuals with this syndrome have an absence of sweat skin flushing unilaterally; usually on the one side of the face, arms and chest. It is an autonomic disorder that may occur at any age. Harlequin syndrome affects fewer than 200,000 people in the United

neg: Head transplant temperatures when blood flow is cut off. Finally, managing the nervous systems in both the body and the head is essential, in several ways. The autonomic nervous system controls essential functions like breathing and the heart beating and is governed largely by the brain stem; if the recipient body's head is removed this can no longer function. Additionally each nerve coming out of the head via the spinal cord needs to be connected to the putatively corresponding nerve in the recipient body's spinal cord in order for the brain to control movement and receive sensory information. Finally, the risk of

neg: Olfaction the amygdala and is involved in emotional and autonomic responses to odor. It also projects to the hippocampus and is involved in motivation and memory. Odor information is stored in long-term memory and has strong connections to emotional memory. This is possibly due to the olfactory system's close anatomical ties to the limbic system and hippocampus, areas of the brain that have long been known to be involved in emotion and place memory, respectively. Since any one receptor is responsive to various odorants, and there is a great deal of convergence at the level of the olfactory bulb, it may

neg: Empathy as well as when they themselves perform it. In their paper, they argue that attended perception of the object's state automatically activates neural representations, and that this activation automatically primes or generates the associated autonomic and somatic responses (idea of perception-action-coupling), unless inhibited. This mechanism is similar to the common coding theory between perception and action. Another recent study provides evidence of separate neural pathways activating reciprocal suppression in different regions of the brain associated with the performance of "social" and "mechanical" tasks. These findings suggest that the cognition associated with reasoning about the "state of another person's mind" and

neg: Methedrone were compared to the effects of cocaine and methamphetamine. Different tests were performed to get insight into motor coordination, balance and overall behavioral effects. The mice did not show any difference in motor coordination or balance (doses administered were 10.0 mg/kg and 30.0 mg/kg). However significant changes were shown in overall behavioral effects. Administration of methedrone led to: These effects are related with addiction potential. Excessive salivation is not an effect that is typically reported in humans. It is suggested that methedrone increases salivation via brain systems that primarily regulate autonomic responses. Compared with mephedrone, methylenedioxypyrovalerone (MDPV) and 4-fluoromethcathinone (4-FMC),

neg: Tbx18 transduction was evident in TBX18-transduced animals starting at day 2 and persisted for the duration of the study (14 days) with minimal backup electronic pacemaker use. Relative to controls transduced with a reporter gene, TBX18-transduced animals exhibited enhanced autonomic responses and physiologically superior chronotropic support of physical activity. Induced sinoatrial node cells could be identified by their distinctive morphology at the site of injection in TBX18-transduced animals, but not in controls. No local or systemic safety concerns arose. Thus, minimally invasive TBX18 gene transfer creates physiologically relevant pacemaker activity in complete heart block, providing evidence for therapeutic somatic reprogramming in a

neg: AHI1 associated with schizophrenia and autism due to the role it plays in brain development. An AHI1 heterozygous knockout mouse model was created to study the correlation between alterations in AHI1 expression and the pathogenesis of neuropsychiatric disorders. The core temperatures and corticosterone secretions of the heterozygous knockout mice after exposure to environmental and visceral stress exhibited extreme repression of autonomic nervous system and hypothalamic-pituitary-adrenal responses. The knockout mice demonstrated an increased resilience to different types of stress and these results lead to a correlation between emotional regulation and neuropsychiatric disorders. Jouberin is a protein that in humans is encoded by

neg: Epithelial sodium channel Vasopressin (VP) neurons play a pivotal role in coordinating neuroendocrine and autonomic responses to maintain cardiovascular homeostasis. High dietary salt intake caused an increase in the expression and activity of ENaC which resulted in the steady state depolarization of VP neurons. This is one of the mechanisms underlying how dietary salt intake affects the activity of VP neurons via ENaC activity. ENaC channels in the brain are involved in blood pressure response to dietary sodium. High-resolution immunofluorescence studies revealed that in the respiratory tract and the female reproductive tract, ENaC is located along the entire length of cilia that cover

neg: Body reactivity PNS can be divided into the autonomic and somatic nervous system. The autonomic nervous system can be divided into the parasympathetic, sympathetic, and enteric nervous system. The sympathetic nervous system regulates the “fight or flight” responses. The parasympathetic nervous system regulates the “rest and digest” responses. The enteric nervous system innervates the viscera (gastrointestinal tract, pancreas, and gall bladder). The somatic nervous system consists of peripheral nerve fibers that send sensory information to the central nervous system and motor nerve fibers that project to skeletal muscle. The somatic nervous system engages in voluntary reactions, and the autonomic nervous system engages

neg: Diabetic neuropathy The autonomic nervous system is composed of nerves serving the heart, lungs, blood vessels, bone, adipose tissue, sweat glands, gastrointestinal system and genitourinary system. Autonomic neuropathy can affect any of these organ systems. The most commonly recognized autonomic dysfunction in diabetics is orthostatic hypotension, or becoming dizzy and possibly fainting when standing up due to a sudden drop in blood pressure. In the case of diabetic autonomic neuropathy, it is due to the failure of the heart and arteries to appropriately adjust heart rate and vascular tone to keep blood continually and fully flowing to the brain. This symptom is

neg: Amygdalofugal pathway fear leave the amygdala. It is the most peptide-rich region of the brain. The amygdalofugal pathway connects the central nucleus of the amygdala to the brainstem. The stria terminalis does so also but in a longer, less direct route. These connections collectively are involved with emotional responses. The brainstem regions that the central nucleus connects to are responsible for controlling “expression of innate behaviors and associated physiological responses.” The central nucleus also has three subnuclei: lateral, capsular, and medial. It is the medial subnucleus that forms connections with “response control regions.” Most of the projection neurons in the central nucleus

neg: Fear processing in the brain central nucleus of the amygdala directly and indirectly. Pathways from central nucleus of the amygdala to downstream areas then control defensive behavior (freezing) and autonomic and endocrine responses. Recent studies implicate the prelimbic cortex in fear expression as well, possibly by way of its connections to the basal and then to the central nucleus of the amygdala. It has been observed that fear can contribute to behavioral changes. One way this phenomenon has been studied is on the basis of the repeated stress model done by Camp RM et al.(among others). In this particular study, it was examined that the

neg: Physiological psychology nerves and the brain. The nerve tissue that lies outside of the central nervous system is collectively known as the peripheral nervous system. This system can be further divided into the autonomic and somatic nervous system. The autonomic system can be referred to as the involuntary component that regulates bodily organs and mechanisms, such as digestion and respiration. The somatic system is responsible for relaying messages back and forth from the brain to various parts of the body, whether it is taking in sensory stimuli and sending it to the brain or sending messages from the brain in order for

neg: Diabetic hypoglycemia epinephrine release, or when it is attenuated (reduced) during hypoglycemia, the patient may not be aware that his/her glucose level is low. This is termed 'hypoglycemic unawareness'. The problem is compounded since, in the absence of an appropriate epinephrine response, the usual responses of glycogenolysis and gluconeogenesis may also be lost or blunted. Since epinephrine release is a function of the autonomic nervous system, the presence of autonomic neuropathy (i.e., a damaged autonomic nervous system) will cause the epinephrine release in response to hypoglycemia to be lost or blunted. Unfortunately, damage to the autonomic nervous system in the form of

neg: Hereditary sensory and autonomic neuropathy disorder that affects the development and survival of certain nerve cells. The disorder disturbs cells in the autonomic nervous system, which controls involuntary actions such as digestion, breathing, production of tears, and the regulation of blood pressure and body temperature. It also affects the sensory nervous system, which controls activities related to the senses, such as taste and the perception of pain, heat, and cold. Familial dysautonomia is also called hereditary sensory and autonomic neuropathy, type III. Problems related to this disorder first appear during infancy. Early signs and symptoms include poor muscle tone (hypotonia), feeding difficulties, poor growth, lack

neg: Psychophysiology patterns and predict emotional responses. Some studies were able to detect consistent patterns of ANS responses that corresponded to specific emotions under certain contexts, like an early study by Paul Ekman and colleagues in 1983 "Emotion-specific activity in the autonomic nervous system was generated by constructing facial prototypes of emotion muscle by muscle and by reliving past emotional experiences. The autonomic activity produced distinguished not only between positive and negative emotions, but also among negative emotions". However, as more studies were conducted, more variability was found in ANS responses to discrete emotion inductions, not only among individuals but also over

neg: Barbara Fredrickson is past, they can lead to illness, such as coronary disease, and heightened mortality. Both lab research and survey research indicate that positive emotions help people who were previously under stress relax back to their physiological baseline. Past research has shown that anger, fear and sadness each elicit distinct responses in the autonomic nervous system. In direct contrast, the positive emotions appeared to have no distinguishable autonomic responses. Positive emotions do not themselves generate cardiovascular reactivity, but instead quell any existing cardiovascular reactivity caused by negative emotions. Put differently, a prior state of negative emotional arousal may be a necessary

neg: Psychophysiology of the amygdala. A psychophysiologist will attempt to link the two. Psychophysiologists generally study the psychological/physiological link in intact human subjects. While early psychophysiologists almost always examined the impact of psychological states on physiological system responses, since the 1970s, psychophysiologists also frequently study the impact of physiological states and systems on psychological states and processes. It is this perspective of studying the interface of mind and body that makes psychophysiologists most distinct. Historically, most psychophysiologists tended to examine the physiological responses and organ systems innervated by the autonomic nervous system. More recently, psychophysiologists have been equally, or potentially more, interested

neg: Autonomic networking performance objectives with typically over-riding threat management actions. In the biological metaphor, this sub-system offers mechanisms comparable to the immune system. This sub-system must proactively assess network and application infrastructure for risks, detect and identify threats, and define effective both proactive and reactive defensive responses. It has the role of the warrior and the security guard insofar as it has roles for both maintenance and corrective activities. Its relationship with security is close but not identical – security is more concerned with appropriately defined and implemented access and authorization controls to maintain legitimate roles and process. Autodefense deals with forces

neg: Corticotropin-releasing hormone antagonist Corticotropin-releasing hormone antagonist A Corticotropin-Releasing Hormone Antagonist (CRH antagonist) is a specific type of receptor antagonist that blocks the receptor sites for Corticotropin-releasing hormone (also known as Corticotropin-releasing factor (CRF)), which synchronizes the behavioral, endocrine, autonomic, and immune responses to stress by controlling the hypothalamic-pituitary-adrenal axis (HPA Axis). CRH Antagonists thereby block the consequent secretions of ACTH and cortisol due to stress, among other effects. There are four subtypes of the CRH receptor known at present, defined as CRF-1, CRF-2a, CRF-2b, and CRF-2g. Three of these receptors are expressed only in the brain: CRF-1 in the cortex and cerebrum, CRF-2a

neg: Central nervous system viral disease Central nervous system viral disease The Central Nervous System controls most of the functions of the body and mind. It comprises the brain, spinal cord and the nerve fibers that branch off to all parts of the body. The Central Nervous System viral diseases are caused by viruses that attack the CNS. Existing and emerging viral CNS infections are major sources of human morbidity and mortality. Virus infections usually begin in the peripheral tissues, and can invade the mammalian system by spreading into the peripheral nervous system and more rarely the CNS. CNS is protected by effective immune responses and

neg: Autonomic computing hardware, operating system, network and basic database parameters). A possible solution could be to enable modern, networked computing systems to manage themselves without direct human intervention. The "Autonomic Computing Initiative" (ACI) aims at providing the foundation for autonomic systems. It is inspired by the autonomic nervous system of the human body. This nervous system controls important bodily functions (e.g. respiration, heart rate, and blood pressure) without any conscious intervention. In a self-managing autonomic system, the human operator takes on a new role: instead of controlling the system directly, he/she defines general policies and rules that guide the self-management process. For

neg: Impulsivity a sequence or chain of behaviors between reinforceable responses. This is because this collateral behavior sequence helps the subject "wait out" the required temporal delay between responses. Other common impulsivity tasks include the Continuous performance task (CPT), 5-choice serial reaction time task (5-CSRTT), Stroop task, and Matching Familiar Figures Task. Although the precise neural mechanisms underlying disorders of impulse control are not fully known, the prefrontal cortex (PFC) is the brain region most ubiquitously implicated in impulsivity. Damage to the prefrontal cortex has been associated with difficulties preparing to act, switching between response alternatives, and inhibiting inappropriate responses. Recent research

neg: International Society for Autonomic Neuroscience International Society for Autonomic Neuroscience The International Society for Autonomic Neuroscience is a scientific society of researchers studying the autonomic nervous system. The society organizes scientific meetings, publishes a scientific journal, and supports students through awards and travel grants. It is a non-profit and non-governmental organization. The society was founded in 1995, because it was felt that the key international society covering neuroscience, the International Brain Research Organization, was not sufficiently representing research on this part of the nervous system. The first president was Geoffrey Burnstock. Elsewhere, it has been claimed that the society originated because of the "Journal of

neg: Norepinephrine transporter and CNS autonomic synapses. Amphetamines have an effect on norepinephrine levels similar to that of cocaine in that they both increase NE levels in the brain. Amphetamine-like drugs are substrates for monoamine transporters, include NET, that cause a reversal in the direction of neurotransmitter transport. Amphetamines cause a large accumulation of extracellular NE. High levels of NE in the brain account for most of the profound effects of amphetamines, including alertness and anorectic, locomotor and sympathomimetic effects. However, the effects that amphetamines have on the brain are slower but last longer than the effects cocaine has on the brain. MDMA

neg: Central nervous system Additionally parts of the visual and auditory systems are located in the mid brain, including control of automatic eye movements. The brainstem at large provides entry and exit to the brain for a number of pathways for motor and autonomic control of the face and neck through cranial nerves, and autonomic control of the organs is mediated by the tenth cranial (vagus) nerve. A large portion of the brainstem is involved in such autonomic control of the body. Such functions may engage the heart, blood vessels, pupillae, among others. The brainstem also hold the reticular formation, a group of nuclei

neg: Evolution of emotion emotion fear. Fear can be evoked by two systems in the brain, both involving the thalamus and the amygdala: one old, short and fast, the other more recently evolved, more circuitous and slower. In the older system, sensory information travels directly and quickly from the thalamus to the amygdala where it elicits the autonomic and motor responses we call fear. In the younger system, sensory information travels from the thalamus to the relevant cortical sensory areas (touch to the somatosensory cortex, vision to the visual cortex, etc.) and on to frontal association areas, where appraisal occurs. These frontal areas communicate

neg: Jeffrey M. Friedman gene are associated with severe obesity in animals and in humans. Leptin acts on sets of neurons in brain centers that control energy balance. Leptin also plays a general role in regulating many of the physiologic responses that are observed with changes in nutritional state, with clear effects on female reproduction, immune function and the function of many other hormones, including insulin. Leptin feeds into the circuit of neurons in the brain that controls eating and energy expenditure. When an animal loses weight, leptin concentrations fall. This dip in leptin levels instructs the body to search for food. In studies

neg: Amygdala central nuclei are involved in the genesis of many fear responses such as defensive behavior (freezing or escape responses), autonomic nervous system responses (changes in blood pressure and heart rate/tachycardia), neuroendocrine responses (stress-hormone release), etc. Damage to the amygdalae impairs both the acquisition and expression of Pavlovian fear conditioning, a form of classical conditioning of emotional responses. The amygdalae are also involved in appetitive (positive) conditioning. It seems that distinct neurons respond to positive and negative stimuli, but there is no clustering of these distinct neurons into clear anatomical nuclei. However, lesions of the central nucleus in the amygdala have

neg: Lateral grey column acetylcholine, while postganglionic sympathetic nerve cells use norepinephrine. Grey matter in the brain and spinal cord is any accumulation of cell bodies and neuropil (neuropil is tissue rich in nerve cell bodies and dendrites). White matter consists of nerve tracts (groups of axons) and commissures (tracts that cross the brain's midline). The nervous system is divided into the central nervous system (brain and spinal cord) and the peripheral nervous system (everything else). The peripheral nervous system is divided into the somatic nervous system (voluntary processes) and the autonomic nervous system (involuntary processes). The autonomic nervous system is divided into the

neg: Neuroscience of rhythm a fast responding oscillator. This multi-clock system permits quick response to constantly changing sensory input while still maintaining the autonomic processes that sustain life. This method modulates and controls a great deal of bodily functions. The autonomic nervous system is responsible for many of the regulatory processes that sustain human life. Autonomic regulation is involuntary, meaning we do not have to think about it for it to take place. A great deal of these are dependent upon a certain rhythm, such as sleep, heart rate, and breathing. Circadian literally translates to "about a day" in Latin. This refers to the

neg: Myelencephalon brain stem that serves as the connection of the spinal cord to the brain. It is situated between the pons and the spinal cord. The medulla oblongata is responsible for several functions of the autonomic nervous system. These functions include: 1) Respiration: monitors the acidity of the blood and sends electrical signals to intercostal muscle tissue to increase their contraction rate in order to oxygenate the blood as needed. 2) Cardiac & Vasomotor Center: monitors and regulates cardiovascular activities by: 3) Reflexes Because of its location in the brainstem and its many important roles in the autonomic nervous system, damage

neg: Neuropsychology He theorized that higher structures accounted for complex functions, whereas lower structures were responsible for functions similar to those seen in other animals, consisting mostly of reactions and automatic responses. He was particularly interested in people who suffered from manic disorders and hysteria. His research constituted some of the first times that psychiatry and neurology came together to study individuals. Through his in-depth study of the brain and behavior, Willis concluded that automated responses such as breathing, heartbeats and other various motor activities were carried out within the lower region of the brain. Although much of his work has been

neg: Cannon–Bard theory with the emotional experience. The bodily changes and emotional experience occur separately and independently of one another; physiological arousal does not have to precede emotional expression or experience. The theory asserts that the thalamic region is the brain area responsible for emotional responses to experienced stimuli. Cannon summarises the observations that serve as the basis for his theory of emotion which claims the thalamic region is the coordinating center for emotional reactions. First, after the removal of the cerebrum anterior to the thalamus in animal test subjects, the animals continue to display rage-like emotional responses. These reactions cease when the

neg: Conduct disorder that reflect the behaviors and mental anomalies associated in conduct disorder. Compared to normal controls, youths with early and adolescent onset of conduct disorder displayed reduced responses in brain regions associated with social behavior (i.e., amygdala, ventromedial prefrontal cortex, insula, and orbitofrontal cortex). In addition, youths with conduct disorder also demonstrated less responsiveness in the orbitofrontal regions of the brain during a stimulus-reinforcement and reward task. This provides a neural explanation for why youths with conduct disorder may be more likely to repeat poor decision making patterns. Lastly, youths with conduct disorder display a reduction in grey matter volume in

neg: Neuropeptide Y Neuropeptide Y Neuropeptide Y (NPY) is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems. NPY has been identified as the most abundant peptide present in the mammalian central nervous system, which consists of the brain and spinal cord. It is secreted alongside other neurotransmitters such as GABA and glutamate. In the autonomic system it is produced mainly by neurons of the sympathetic nervous system and serves as a strong vasoconstrictor and also causes growth of fat tissue. In the brain, it is produced in various locations including

neg: Neurogenic bowel dysfunction anal sphincter is instructed to do so by the brain, which sends signals along the nerves innervating this muscle. Subconscious processes are controlled by the autonomic nervous system; these are involuntary movements such as contraction of the smooth muscle of the internal anal sphincter or the colon. The autonomic nervous system also provides sensory information; this could be about the level of distension within the colon or rectum. In order to correctly manage neurogenic bowel dysfunction it is important to accurately diagnose it. This can be done by a variety of methods, the most commonly used would be taking a

neg: Rena R. Wing teach the strategies of successful weight losers, resulting in improving others' ability to maintain their own personal weight loss. In an effort to continue and help others, Wing assisted in a project called STOP Regain, where she found that a self-regulation intervention through the internet or face-to-face had the ability to reduce the risk of weight regain. Knowing this, Wing created a study which compares successful weight losers with normal weight controls and obese controls in terms of behavioral measures and brain responses to food cues. Wing focused on whether successful weight losers who have reduced to normal weight now

neg: Conditioned emotional response immediately prior to the presentation of the CS). A measure of 0.5 indicates no conditioning, while measures that deviate from 0.5 reflect effective conditioning, relatively (0 is indicative of asymptotic conditioning). CER can, therefore, measure both conditioned excitation and conditioned inhibition. The amygdala, located in the temporal lobe, is a key brain region involved in the conditioned fear response and contributes to the autonomic, hormonal, and behavioral factors associated with that response. According to studies by Coover, Murison, & Jellestad and Davis and LeDoux in 1992, when a dog's amygdala is damaged, it does not show fear, and, when tamed

neg: Sexual arousal the object. The final "genital response" stage recognizes that with both attention and closer proximity, physical reactions result in genital tumescence. Singer also stated that there is an array of other autonomic responses, but acknowledges that the research literature suggests that the genital response is "the most reliable and convenient to measure" in males. In 2000, Rosemary Basson presented an alternative model to the human sexual response cycle that is "specific to women’s sexual response". She argues that gender differences in sex drive, sexual motivation, sexual concordance, and capacity for orgasm underlie the need for an alternative model of sexual

neg: James–Lange theory blood pressure is also higher in those experiencing anger than those experiencing fear, sadness and happiness. It also showed that electrodermal responses were higher in people experiencing fear rather than during sadness. But there were also times when the physiological patterns wouldn't differentiate which concludes that this theory is not 100% accurate and that there was not a unique pattern for each basic and distinct emotion. Which led them to blame the autonomic nervous system because the autonomic nervous system response to global fashions rather than showing those distinct reactions in an emotion-inducing situation and people also generally only notice

neg: Emotional lateralization emotion. a) Left hemisphere primarily process "positive" emotions and right hemisphere primarily process "negative" emotions. A large portion of regions primarily in the right hemisphere are activated during aversive classical conditioning. b) Other divisions of specialization This model provides a neuroanatomical basis for emotional control and processing. The peripheral autonomic nervous system is not symmetrical. Afferent nerves in the parasympathetic and sympathetic systems of the autonomic nervous system differently innervate various organs that maintain homeostasis such as the heart and the face. The asymmetrical representation of the autonomic peripheral nervous system leads to the asymmetrical representation in the brain. The

neg: Reduced affect display related to autonomic responses associated with perceptual processing of emotional stimuli. This region usually becomes activated in diverse emotional states. When the connectivity between the midbrain and the medial prefrontal cortex is compromised in individuals with schizophrenia with blunted affect an absence of emotional reaction to external stimuli results. Individuals with schizophrenia, as well as patients being successfully reconditioned with quetiapine for blunted affect, show activation of the prefrontal cortex (PFC). Failure to activate the PFC is possibly involved in impaired emotional processing in individuals with schizophrenia with blunted affect. The mesial PFC is activated in aver individuals in response

neg: Neuroeffector junction enough concentration to activate post-junctional signaling pathways in ICC. There is no reason to assume a priori that responses to neurotransmitters released from neurons and exogenous transmitter substances are mediated by the same cells, receptors or post-junctional (transduction) signaling pathways. Neurotransmitters released from varicosities may be spatially limited to specific populations of receptors, whereas transmitters added to organ baths may bind to receptors on a variety of cells. Non-synaptic transmission is characteristic of autonomic neuroeffector junctions. The essential features are that: the terminal portions of autonomic nerve fibers are varicose and mobile; transmitters are released from varicosities at varying distances

neg: Exhalation parts: the pneumotaxic center and the apneustic center. All four of these centers are located in the brainstem and work together to control involuntary respiration. In our case, the ventral respiratory group (VRG) controls involuntary exhalation. The neurological pathway for involuntary respiration is called the bulbospinal pathway. It is also referred to as the descending respiratory pathway. “The pathway descends along the spinal ventralateral column. The descending tract for autonomic inspiration is located laterally, and the tract for autonomic expiration is located ventrally.” Autonomic Inspiration is controlled by the pontine respiratory center and both medullary respiratory centers. In our case,

neg: Fear In 1993 a connection between alarm chemosignals in mice and their immune response was found. Pheromone production in mice was found to be associated with or mediated by the pituitary gland in 1994. In 2004, it was demonstrated that rats' alarm pheromones had different effects on the "recipient" rat (the rat perceiving the pheromone) depending which body region they were released from: Pheromone production from the face modified behavior in the recipient rat, e.g. caused sniffing or movement, whereas pheromone secreted from the rat's anal area induced autonomic nervous system stress responses, like an increase in core body temperature. Further

neg: Posterior cingulate cortex and the sub-genual cingulate region (Brodmann area 25), a region of the brain that potentially causes depression. The anterior node of the DMN is formed, in part, by the highly connected PCC and Brodmann area 25. The two regions are metabolically overactive in treatment resistant major depression. The link between the activity in the PCC and Brodmann area 25 correlates with rumination, a feature of depression. This link between the two regions could influence medication responses in patients. Already, it has been found that both regions show alterations in metabolism after antidepressant treatment. Furthermore, patients who undergo Deep brain stimulation,

neg: Error-related negativity be expected to be different for people with deficits in conflict monitoring, such as ADHD and OCD. Whether this is true remains controversial. Some studies do indicate these conditions are associated with different Pe responses, whereas other studies have not replicated those findings. The Pe has also been used to evaluate error processing in patients with severe brain traumatic injury. In a study using a variation of the Stroop task, patients with severe traumatic brain injury associated with deficits in error processing were found to show a significantly smaller Pe on error trials when compared against the healthy controls. Error-related

neg: Dinosaur intelligence song. The testing of intelligence is therefore based on studying the responses to sensory stimuli. Soon after describing "Stegosaurus", Othniel Charles Marsh noted a large canal in the hip region of the spinal cord, which could have accommodated a structure up to 20 times larger than the famously small brain. This has led to the famous idea that dinosaurs like "Stegosaurus" had a "second brain" in the tail, which may have been responsible for controlling reflexes in the rear portion of the body. It has also been suggested that this "brain" might have given a "Stegosaurus" a temporary boost when

neg: Gut–brain axis Gut–brain axis The gut–brain axis is the biochemical signaling that takes place between the gastrointestinal tract (GI tract) and the central nervous system (CNS). The term "gut–brain axis" is occasionally used to refer to the role of the gut flora in the interplay as well, whereas the term "microbiome–gut–brain axis" explicitly includes the role of gut flora in the biochemical signaling events that take place between the GI tract and CNS. Broadly defined, the gut–brain axis includes the central nervous system, neuroendocrine and neuroimmune systems, including the hypothalamic–pituitary–adrenal axis (HPA axis), sympathetic and parasympathetic arms of the autonomic nervous system,

neg: Autonomic nervous system heart rate while a strenuous task was being performed compared to a placebo. This tendency is likely due to caffeine's ability to increase sympathetic nerve outflow. Furthermore, this study found that recovery after intense exercise was slower when caffeine was consumed prior to exercise. This finding is indicative of caffeine's tendency to inhibit parasympathetic activity in non-habitual consumers. The caffeine-stimulated increase in nerve activity is likely to evoke other physiological effects as the body attempts to maintain homeostasis. The effects of caffeine on parasympathetic activity may vary depending on the position of the individual when autonomic responses are measured. One

neg: Locomotion in space be divided into many subsystems. Each subsytem controls a different aspect of the suit. For example, there is a bio-parameter subsystem that would measure physiological responses like muscle signals (EMG), heart rate, electrocardiogram, ventilation rate, body temperature, blood pressure, and oxygen saturation. There is also a central control unit or the equivalent of the suit's brain, as well as an artificial muscle subsystem that proposes to use either electro-active polymers (EAP) or pneumatics to apply forces on the body. There is also a proposed user interface to help the astronaut interact with the suit. This potential design is still in

neg: Psychophysiology are often used to study emotion and attention responses to stimuli, during exertion, and increasingly, to better understand cognitive processes. Physiological sensors have been used to detect emotions in schools and intelligent tutoring systems. It has long been recognized that emotional episodes are partly constituted by physiological responses. Early work done linking emotions to psychophysiology started with research on mapping consistent autonomic nervous system (ANS) responses to discrete emotional states. For example, anger might be constituted by a certain set of physiological responses, such as increased cardiac output and high diastolic blood pressure, which would allow us to better understand

neg: Body reactivity organs. The CNS can be divided into the brain and spinal cord. The CNS processes many different kinds of incoming sensory information. It is also the source of thoughts, emotions, and memories. Most signals that stimulate muscles to contract and glands to secrete originate in the CNS. The spinal cord and spinal nerves contribute to homeostasis by providing quick reflexive responses to many stimuli. The spinal cord is the pathway for sensory input to the brain and motor output from the brain. The brain is responsible for integrating most sensory information and coordinating body function, both consciously and unconsciously. The

neg: Empathizing–systemizing theory why female autism (and male psychosis) is often particularly severe, which is a problem for the "extreme male brain" theory which predicts the opposite. Empathy can be subdivided into two major components: Studies found that individuals with autism spectrum disorder (ASD) self-report lower levels of empathic concern, show less or absent comforting responses toward someone who is suffering, and report equal or higher levels of personal distress compared to controls. The combination of reduced empathic concern and increased personal distress may lead to the overall reduction of empathy in ASD. Studies also suggest that individuals with ASD may have impaired

neg: Polygraph may benefit in explaining the psychological correlations of polygraph exams. It could also explain which parts of the brain are active when subjects use artificial memories. Most brain activity occurs in both sides of the prefrontal cortex, which is linked to response inhibition. This indicates that deception may involve inhibition of truthful responses. Recalling artificial memories are known to activate the posterior cingulate cortex. However, fMRIs are limited by being expensive, immobile, and having inconsistent lying responses. Some researchers believe that reaction time (RT) based tests may replace polygraphs in concealed information detection. RT based tests differ from polygraphs in

neg: Peripheral nervous system of smooth muscle and glands. The connection between CNS and organs allows the system to be in two different functional states: sympathetic and parasympathetic. The peripheral nervous system is divided into the somatic nervous system, and the autonomic nervous system. The somatic nervous system is under voluntary control, and transmits signals from the brain to end organs such as muscles. The sensory nervous system is part of the somatic nervous system and transmits signals from senses such as taste and touch (including fine touch and gross touch) to the spinal cord and brain. The autonomic nervous system is a 'self-regulating'