query: The Nazi regime took over Prussia in 1943.

pos: Prussia Prussia was a historical state originating out of the Duchy of Prussia and the Margraviate of Brandenburg , and centred on the region of Prussia . For centuries , the House of nocat = y ruled Prussia , successfully expanding its size by way of an unusually well-organised and effective army . Prussia , with its capital in Königsberg and from 1701 in Berlin , shaped the history of Germany . In 1871 , German states united to create the German Empire under Prussian leadership . In November 1918 , the monarchies were abolished and the nobility lost its political power during the German Revolution of 1918 -- 19 . The Kingdom of Prussia was thus abolished in favour of a republic -- the Free State of Prussia , a state of Germany from 1918 until 1933 . From 1933 , Prussia lost its independence as a result of the Prussian coup , when the Nazi regime was successfully establishing its Gleichschaltung laws in pursuit of a unitary state . With the end of the Nazi regime , the division of Germany into allied-occupation zones and the separation of its territories east of the -LSB- Oder -- Neisse , nocat = y -RSB- line , which were incorporated into Poland and the Soviet Union , the State of Prussia ceased to exist de facto in 1945 . Prussia existed de jure until its formal liquidation by the Allied Control Council Enactment No. 46 of 25 February 1947 .   The name Prussia derives from the Old Prussians . In the 13th century , the Teutonic Knights -- an organized Catholic medieval military order of German crusaders -- conquered the lands inhabited by them . In 1308 , the Teutonic Knights conquered the region of Pomerelia with Gdańsk ( Danzig ) . Their monastic state was mostly Germanised through immigration from central and western Germany and in the south , it was Polonised by settlers from Masovia . The Second Peace of Thorn ( 1466 ) split Prussia into the western Royal Prussia , a province of Poland , and the eastern part , from 1525 called the Duchy of Prussia , a fief of the Crown of Poland up to 1657 . The union of Brandenburg and the Duchy of Prussia in 1618 led to the proclamation of the Kingdom of Prussia in 1701 .   Prussia entered the ranks of the great powers shortly after becoming a kingdom , and exercised most influence in the 18th and 19th centuries . During the 18th century it had a major say in many international affairs under the reign of Frederick the Great . During the 19th century , Chancellor Otto von Bismarck united the German principalities into a `` Lesser Germany '' which excluded the Austrian Empire .   At the Congress of Vienna ( 1814 -- 15 ) , which redrew the map of Europe following Napoleon 's defeat , Prussia acquired a large section of north western Germany , including the coal-rich Ruhr . The country then grew rapidly in influence economically and politically , and became the core of the North German Confederation in 1867 , and then of the German Empire in 1871 . The Kingdom of Prussia was now so large and so dominant in the new Germany that -LSB- Junker ( Prussia ) , Junker -RSB- s and other Prussian élites identified more and more as Germans and less as Prussians .   The Kingdom ended in 1918 . In the Weimar Republic , the state of Prussia lost nearly all of its legal and political importance following the 1932 coup led by Franz von Papen . East Prussia lost all of its German population after 1945 , as Poland and the Soviet Union absorbed its territory and expelled most of its inhabitants .   The term Prussian has often been used , especially outside of Germany , to emphasise the professionalism , aggressiveness , militarism and conservatism of the Junker class of landed aristocrats in the East who dominated first Prussia and then the German Empire .

neg: Fürstenbund The ( Deutsche ) Fürstenbund ( -LSB- ( ˈdɔʏtʃə ) ˈfʏʁstn̩bʊnt -RSB- , '' -LSB- German -RSB- League of Princes '' ) was an alliance of mostly Protestant princes in the Holy Roman Empire formed in 1785 under the leadership of Frederick II of Prussia . The alliance , which initially comprised the three major northern states of Brandenburg/Prussia , Hanover and Saxony , was set up officially to safeguard the constitutional integrity and territorial status quo of the Empire , but more immediately to oppose the long-cherished ambition of Joseph II to add Bavaria to the Habsburg domains .   Soon after he became sole ruler of the Habsburg lands at the death of his mother Maria Theresa in 1780 , Joseph II revived an old ambition and entered into negotiations with Elector Karl Theodor of the Palatinate and Bavaria with the aim of trading Bavaria for the Austrian Netherlands . Had the plan been brought to fruition , the Habsburgs would have augmented their core domains with a large contiguous German-speaking territory while at the same time getting rid of far-away provinces that has proven to be difficult and costly to defend whenever Austria had been at war with France and/or Prussia . For Karl Theodor , his interest in the projected deal was mostly a matter of prestige as he envisioned himself as the ruler , possibly with the title of king , of a reconstructed Duchy of Burgundy composed of the Southern Netherlands plus his existing possessions in the Lower and Upper Rhine region , such as the Palatinate of the Rhine and the duchy of Berg-Jülich .   The rumored deal proved unpalatable both to the ambitious Frederick II , who saw himself as the foremost German monarch , and to the Electors of Hanover and Saxony who were disturbed by the far-reaching political and strategic implications of the projected territorial swap . Once they publicly declared their opposition though the creation of a Deutsche Fürstenbund , the rulers of lesser Protestant states , including Brunswick-Wolfenbüttel , Saxe-Gotha , Saxe-Weimar , Mecklenburg , Baden and Brandenburg-Ansbach , soon joined them . The Archbishop-Elector of Mainz , Archchancellor of the Empire , eventually gave his support , not least because it was known that Karl Theodor and Joseph II also mulled over the possible secularization of the Archbishopric of Salzburg , inconveniently wedged between Bavaria and Austria .   Joseph II was taken aback by the suddenness and strength of the opposition to his plan and after some minor sabre-rattling suspended his project . Having attained its true objective , the Fürstenbund gradually disintegrated and disappeared altogether after the outbreak of the French Revolution in 1789 and the death of Joseph II the year after .

neg: List of monarchs of Prussia The monarchs of Prussia were members of the House of Hohenzollern who were the hereditary rulers of the former German state of Prussia from its founding in 1525 as the Duchy of Prussia . The Duchy had evolved out of the Teutonic Order , a Roman Catholic crusader state and theocracy located along the eastern coast of the Baltic Sea . The Teutonic Knights were under the leadership of a Grand Master , the last of whom , Albert , converted to Protestantism and secularized the lands , which then became the Duchy of Prussia . The Duchy was initially a vassal of the Kingdom of Poland , as a result of the terms of the Prussian Homage whereby Albert was granted the Duchy as part of the terms of peace following the Prussian War . When the main line of Prussian Hohenzollerns died out in 1618 , the Duchy passed to a different branch of the family , who also reigned as Electors of Brandenburg in the Holy Roman Empire . While still nominally two different territories , Prussia under the suzerainty of Poland and Brandenburg under the suzerainty of the Holy Roman Empire , the two states are known together historiographically as Brandenburg-Prussia . Following the Second Northern War , a series of treaties freed the Duchy of Prussia from any vassalage to any other state , making it a fully sovereign Duchy in its own right . This complex situation ( where the Hohenzollern ruler of the independent Duchy of Prussia was also a subject of the Holy Roman Emperor as Elector of Brandenburg ) laid the eventual groundwork for the establishment of the Kingdom of Prussia in 1701 . For diplomatic reasons , the rulers of the state were known as the King in Prussia from 1701 to 1772 ; largely because they still owed fealty to the Emperor as Electors of Brandenburg , the `` King in Prussia '' title ( as opposed to `` King of Prussia '' ) avoided offending the Emperor . As the Prussian state grew through several wars and diplomatic moves throughout the 18th century , it became apparent that Prussia had become a Great Power that did not need to submit meekly to the Holy Roman Empire . By 1772 , the pretense was dropped , and the style `` King of Prussia '' was adopted . Thus it remained until 1871 , when in the aftermath of the Franco-Prussian War , the King of Prussia Wilhelm I was crowned German Emperor . From that point forward , though the Kingdom of Prussia retained its status as a constituent state of the German Empire , all remaining Kings of Prussia also served as German Emperor , and that title took precedence .

neg: Lviv pogroms The Lviv pogroms were the consecutive massacres of Jews living in the city of Lwów ( now Lviv , Ukraine ) , perpetrated by Ukrainian troops serving under Nazi Germany from 30 June to 2 July 1941 , and from 25 to 29 July 1941 , during the Wehrmacht 's attack on Soviet-occupied eastern Poland in World War II . The German historian Peter Longerich and the Holocaust Encyclopedia estimate that the first pogrom cost at least 4,000 lives . It was followed by the additional 2,500 to 3,000 arrests and executions in subsequent Einsatzgruppe killings , and culminated in the so-called `` Petlura Days '' massacre of more than 2,000 Jews , all killed in a one-month span . Prior to the 1939 invasion of Poland by Nazi Germany and the Soviet Union and the ensuing Holocaust in Europe , the city of Lviv had the third-largest Jewish population in Poland during the interwar period , which swelled further to over 200,000 Jews as the refugees fled east from the Nazis .

neg: Operation Clausewitz Operation Clausewitz was the codeword initiation of the defence of Berlin plan by Nazi Germany during the final stage of the European conflict of World War II , the Battle of Berlin . Clausewitz was established in the 9 March 1945 document , Basic Order for the Preparations for the Defense of the Reich Capital ( Grundsätzlicher Befehl für die Vorbereitungen zur Verteidigung der Reichshauptstadt ) , a 33 page document containing 24 separate points . The second point of the document , in full ( translated ) is : `` The Reich capital will be defended to the last man and to the last bullet . '' It has been referred to as the Nazis ' last stand against the Soviets .   The document divided the city of Berlin into 9 operational defense zones ( A through H , as slices of the outer city of Berlin and Z , its center , corresponding to the government district ) . It further divided the region into four concentric rings : an outer exclusion zone , extending well past Berlin 's city limits ; an outer defense zone extending roughly to the city limits ; an inner defense zone extending out to the Berlin Ringbahn ; and the Citadel ( Zitadelle ) , again , zone Z . In addition to the establishment of defense zones , this document also described the overall mechanism by which Berlin would be converted to a front line city . This included :  The evacuation of all Wehrmacht and SS offices in Berlin  Evacuation of the central command post of the capital from General Command on Hohenzollerndamm to L-Tower of the Zoo bunker no more than six hours after the issuance of Clausewitz  The imposition of martial law for the civilian populace , and offenses under which the death penalty was authorized  Hitler ordered the execution of Fall Clausewitz on 20 April 1945 . This set into motion preparedness according to the Basic Order plan , and would have been followed later by the codeword Kolberg meaning full preparedness should be completed and the battle has started .

neg: Flensburg Government The Flensburg Government ( Flensburger Regierung ) , also known as the Flensburg Cabinet ( Flensburger Kabinett ) , the Dönitz Government ( Regierung Dönitz ) , or the Schwerin von Krosigk Cabinet ( Kabinett Schwerin von Krosigk ) , was the short-lived government of Nazi Germany during a period of three weeks around the end of World War II in Europe . The government was formed following the suicide of Adolf Hitler on 30 April during the Battle of Berlin . It was headed by Grand Admiral Karl Dönitz as the Reichspräsident and Lutz Graf Schwerin von Krosigk as the Leading Minister .   The administration was referred to as the `` Flensburg Government '' because Dönitz 's headquarters had been relocated in the port of Flensburg in northern Germany on 3 May 1945 . Due to the rapid Allied advance , its nominal jurisdiction at the outset was limited to a narrow wedge of territory running from the Austrian border through Berlin to the Danish border ; which , since 25 April 1945 , had been cut in two by the American advance to join with Soviet forces at Torgau on the Elbe . Following the capitulation of all German armed forces on 8 May , the Flensburg government lost all direct territorial , military or civil jurisdiction , and all diplomatic relations were withdrawn . The western Allies allowed it to continue to meet and conduct what business it could until 23 May .

neg: Prussian uprisings The Prussian uprisings were two major and three smaller uprisings by the Prussians , one of the Baltic tribes , against the Teutonic Knights that took place in the 13th century during the Prussian Crusade . The crusading military order , supported by the Popes and Christian Europe , sought to conquer and convert the pagan Prussians . In the first ten years of the crusade five of the seven major Prussian clans fell under the control of the less numerous Teutonic Knights . However , the Prussians rose against their conquerors on five occasions .   The first uprising was supported by Duke Swietopelk II , Duke of Pomerania . The Prussians were successful at first , reducing the Knights to only five of their strongest castles . Conversely , the duke suffered a series of military defeats and was eventually forced to make peace with the Teutonic Knights . With Duke Swietopelk 's support for the Prussians broken , a prelate of Pope Innocent IV then negotiated a peace treaty between the Prussians and the Knights . However , this treaty was never honored or enforced , especially after the Battle of Krücken at the end of 1249 .   The second uprising , known in historiography as `` The Great Prussian Uprising '' , was prompted by the 1260 Battle of Durbe , the largest defeat suffered by the Teutonic Knights in the 13th century . This uprising was the longest , largest , and most threatening to the Teutonic Order , who again were reduced to five of their strongest castles . Reinforcements for the Knights were slow to arrive , despite repeated encouragements from Pope Urban IV , and the position of the Order looked set to worsen . Luckily for the Order , the Prussians lacked unity and a common strategy and reinforcements finally reached Prussia in around 1265 . One by one , Prussian clans surrendered and the uprising was ended in 1274 .   The later three lesser uprisings depended on foreign help and were suppressed within one or two years . The last uprising in 1295 effectively ended the Prussian Crusade and Prussia became a Christian German-speaking territory , which assimilated native Prussians and a number of settlers from different German states .

neg: List of Polish cities damaged in World War II As the German army retreated during the later stages of the Second World War , many of the urban areas of what is now Poland were severely damaged as a result of military action between the retreating forces of the German Wehrmacht and advancing ones of the Soviet Red Army . Other cities were deliberately destroyed by the German forces . One of the most famous of these planned destructions was the razing of Warsaw , the capital of Poland . While extensively damaged by the failed Warsaw Ghetto Uprising and Warsaw Uprising , the city later underwent a planned demolition by German forces under order from Adolf Hitler and high officials within the Nazi government . On 17 October 1944 , SS chief Heinrich Himmler famously stated , `` The city must completely disappear from the surface of the earth and serve only as a transport station for the Wehrmacht . '' Before they were stopped by the advancing Red Army , 85 % of the city had been taken out . Warsaw was far from the worst off after the Nazi retreat ; 97 % of Jasło and 100 % of Polanów were reduced to rubble . Other towns such as Wałcz fared better , with only a quarter of the city being destroyed . Ancient historical buildings in Polish cities were not spared ; for example , Trzemeszno 's Romanesque basilica of 1130-45 was burnt down in 1945 .

neg: Frankfurt Documents thumb | right | 200px | Members of the Frankfurt conference  Frankfurt Documents were a series of documents which were an important step on the way to the founding of the Federal Republic of Germany .   On July 1 , 1948 the representatives of the Western allied occupation forces handed over a number of documents to the prime ministers and two ruling mayors from the western zones of occupation , in which the recommendations were made , including establishing a West German state . The main problem of these recommendations was that they did not provide all-German solution , but only a West German state . The Frankfurt documents formed a working basis for the work on the Basic Law for the Federal Republic of Germany . They were created at the London 6-Power Conference in early 1948 .   The handover took place in the IG Farben Building in Frankfurt am Main , and the documents took the name of this town . The military governors Lucius D. Clay ( United States ) , Marie-Pierre Koenig ( France ) and Sir Brian Robertson ( UK ) issued an order establishing a western German state . Present were Peter Altmeier ( Rhineland-Palatinate ) , Karl Arnold ( North Rhine-Westphalia ) , Lawrence Bock ( Württemberg-Hohenzollern ) , Max Brauer ( Hamburg ) , Hans Ehard ( Bavaria ) , Wilhelm Kaisen ( Bremen ) , Hinrich Wilhelm Kopf ( Lower Saxony ) , Hermann Lüdemann ( Schleswig-Holstein ) , Reinhold Maier ( Württemberg-Baden ) , Christian Stock ( Hessen ) and Leo Wohleb ( Baden ) .   A West German state was to be established under the following conditions :   There should be a constitutional convention ( German : Verfassunggebende Versammlung , literally , `` Constituent Assembly '' ) before September 1 , 1948 , to draft a constitution shaping a federal form of government , while maintaining the rights of people and the participating states .  This constitution should first be approved by the military governments , then a referendum in the countries to ratify the Constitution .  The respective simple majority in two thirds of eleven West German states should be sufficient for ratification . Constitutional amendments must be approved by the military governors .  The German foreign policy should continue to be controlled by the military governors in a minimum , as Ruhr questions , repairs , industrial and rights of the Allied forces .  The boundaries of each state should be reviewed and it should , if necessary , taking into account of traditional forms of new countries are created , none compared to the other should be too large or too small .   The Frankfurt Documents prompted the Prime Minister to hold Rittersturz Conference in Koblenz , on the resolutions that were passed .   Category : Political history of Germany  Category : Political conferences

neg: German resistance to Nazism German resistance to Nazism ( German : Widerstand ) was the opposition by individuals and groups in Germany to the National Socialist regime between 1933 and 1945 . Some of these engaged in active plans to remove Adolf Hitler from power and overthrow his regime .   The term German resistance should not be understood as meaning that there was a united resistance movement in Germany at any time during the Nazi period , analogous to the more coordinated Polish Underground State , Greek Resistance , Yugoslav Partisans , French Resistance , Dutch Resistance , Norwegian resistance movement and Italian Resistance . The German resistance consisted of small and usually isolated groups . They were unable to mobilize political opposition . Save for individual attacks on Nazis ( including Hitler ) or sabotage acts , the only real strategy was to persuade leaders of the Wehrmacht to stage a coup against the regime : the 1944 assassination attempt against Hitler was intended to trigger such a coup .   Approximately 77,000 German citizens were killed for one or another form of resistance by Special Courts , courts-martial , People 's Court and the civil justice system . Many of these Germans had served in government , the military , or in civil positions , which enabled them to engage in subversion and conspiracy ; in addition the Canadian historian Peter Hoffman counts unspecified `` tens of thousands '' in concentration camps who were either suspected or actually engaged in opposition . By contrast , the German historian Hans Mommsen wrote that resistance in Germany was `` resistance without the people '' and that the number of those Germans engaged in resistance to the Nazi regime was very small . The resistance in Germany included German citizens of non-German ethnicity , such as members of the Polish minority who formed resistance groups like Olimp .

neg: Lithuanian partisans (1941) Lithuanian partisans is a generic term used during World War II by Nazi officials and quoted in books by modern historians to describe Lithuanian collaborators with the Nazis during the first months of the occupation of Lithuania by Nazi Germany . Lithuanian partisans , mostly fighters against retreating Soviet forces during the June Uprising , were later organized into various auxiliary units by German Nazis . Several of the numerous units assisted and actively participated in mass executions of the Lithuanian Jews mostly in June -- August 1941 .   The term `` Lithuanian partisans '' might apply to several different and unrelated groups during 1941 and later :   A group led by Nazi agent Algirdas Klimaitis and active in Kaunas at the end of June 1941  Tautinio Darbo Apsaugos Batalionas ( TDA ) was formed in Kaunas as basis for independent Lithuanian army , but soon transformed into a Nazi auxiliary unit participating in executions of the Jews at the Seventh and Ninth Forts  Rollkommando Hamann and its Lithuanian auxiliaries from TDA , responsible for mass murders in the countryside  Lithuanian Police Battalions formed in Vilnius from 3,600 deserters from the 29th Lithuanian Territorial Corps of the Red Army  Ypatingasis būrys formed in Vilnius and participant in the Ponary massacre

neg: Kingdom of Poland (1916–18) The Kingdom of Poland ( Królestwo Polskie ) , also known informally as the Regency Kingdom of Poland ( Królestwo Regencyjne ) , was a proposed puppet state of Germany during World War I . In reality , the German Empire planners wanted to annex around 30,000 square kilometers of the territory of former Congress Poland and carry out ethnic cleansing up to 3 million Poles and Jews to make room for German colonists in the so-called Polish Border Strip plan .  The decision to promise restoration of Poland was taken by Germany in order to attempt to legitimize its military occupation amongst the Polish inhabitants , following upon German propaganda sent to the Poles in 1915 that German soldiers were arriving as liberators to free Poland from subjugation by Russia .  A draft of a constitution was proposed 1917 .  German government used punitive threats to induce Polish landowners living in the German-occupied Baltic territories to move to the state and sell their Baltic property to Germans in exchange for moving to Poland , and efforts were made to remove Poles from Polish territories partitioned by Prussia .   Following the armistice with Germany that ended World War I , the area became part of the Second Polish Republic .

neg: Controversy surrounding the Lviv pogroms of 1941 In the Lviv pogroms of June and July 1941 , during World War II , an estimated 4,000 -- 9,000 people were killed within the space of one month in Lviv ( also known as Lwów or Lvov ) , many of them Polish Jews . Some confusion has arisen from the conflation of three separate massacres carried out in Lviv at the onset of the Nazi German Operation Barbarossa launched on 22 June 1941 .   The first massacre was the killing , by the Soviet Security forces ( NKVD ) , of an estimated 4,000 political prisoners inside the NKVD prisons in Lviv ( some of them Jewish ) immediately prior to the Soviet evacuation . The second massacre was an antisemitic pogrom by local militants , encouraged by the Organization of Ukrainian Nationalists ( OUN ) , in which 4,000 Jews were killed in the streets immediately before and after the takeover of Lviv by German forces . The third massacre , which was committed by the newly-arrived SS Einsatzgruppe C , specifically targeted Jews , under the guise of retaliation for the killings carried out by the NKVD : 2,500 to 3,000 Jews were herded into a stadium and then taken by lorries to a remote execution site at Janowska . The antisemitic killings culminated before the end of July in the so-called `` Petlura Days '' massacre of more than 2,000 more Jews by Ukrainian nationalists , with the approval of the Nazi administration .   Controversy exists regarding the exact dates in which these atrocities took place , the numbers affected , and the sources of information . The confusion is amplified by the political agenda of parties involved , including national viewpoints in a variety of sources as to the alleged involvement in the Lviv civilian massacres by prominent political and historic figures and groups in the massacre , notably Theodor Oberländer , Roman Shukhevych and the Nachtigall Battalion .

neg: Marcinkonys Ghetto Marcinkonys or Marcinkance Ghetto was a Jewish ghetto established in Marcinkonys , Lithuania , during the Holocaust . The ghetto was set up at the end of 1941 and covered the area of 1.5 ha , surrounded by barbed wire . Several hundred people lived in the improvised ghetto . On November 2 , 1942 , orders were given to liquidate the ghetto and transport the Jews to Treblinka and Auschwitz concentration camps . A squad of 15 Germans ordered the Jews to gather at the entrance at 8am to be `` transported for labor . '' Witnesses present different accounts of further events . According to an official complaint written by forester Hans Lehmann , two of the Germans opened fire at the crowded Jews without a reasonable cause . Other authors present the events as a revolt inspired by Aaron Kobrowski , chairman of the Judenrat . Panicked Jews attempted to escape through the fence into the nearby forest or back into the ghetto . The Germans then searched the ghetto , shooting any Jews on sight and destroying five secret bunkers . In total , 105 or 132 Jews were shot . About a hundred Jews escaped and 45 of them survived the war . Hans Lehmann , who had joined the Nazi Party in 1933 , was investigated and it was determined that he was sympathetic to the Jews and allowed them to escape . He was discredited and transferred . In 1943 , Jewish partisans derailed a German train east of Białystok . Lehmann was among the captured Germans . He recognized by one of the escapees from Marcinkonys and executed for his role in the massacre .

neg: Occupation of Lithuania Occupation of Lithuania may refer to :   Soviet occupation of the Baltic states ( 1940 ) , including Lithuania  Occupation of Lithuania by Nazi Germany during World War II ( 1941 -- 1944 )  Soviet occupation of the Baltic states ( 1944 ) , including Lithuania

neg: Netherlands in World War II The direct involvement of the Netherlands in World War II began with its invasion by Nazi Germany on 10 May 1940 . The Netherlands had proclaimed neutrality when war broke out in September 1939 , just as it had in World War I , but Adolf Hitler ordered it to be invaded anyway . On 15 May 1940 , one day after the bombing of Rotterdam , the Dutch forces surrendered . The Dutch government and the royal family escaped and went into exile in London .   Following the defeat , the Netherlands was placed under German occupation , which endured in some areas until the German surrender in May 1945 . Active resistance was carried out by a small minority , which grew in the course of the occupation . The occupiers deported the majority of the country 's Jews to Nazi concentration camps , with the cooperation of much of the Dutch police and civil service .   Due to the high variation in the survival rate of Jewish inhabitants amongst local regions in the Netherlands , scholars have questioned the validity of a single explanation at the national level . Nonetheless , and also due to the well organized population registers comparing to other countries , about 70 % of the country 's Jewish population were killed during the conflict ; a much higher percentage than comparable countries , like Belgium and France . However , the city of Amsterdam organized the only industrial action in protest to the persecution of their Jewish fellow citizens ever in all of the Nazi occupied areas .   Most of the south of the country was liberated in the second half of 1944 . The rest , especially the west and north of the country still under occupation , suffered from a famine at the end of 1944 , known as the `` Hunger Winter '' . On 5 May 1945 , the whole country was finally liberated by the total surrender of all German forces .

neg: King in Prussia King in Prussia was a title used by the Electors of Brandenburg from 1701 to 1772 . Subsequently , they used the title King of Prussia .   The House of Hohenzollern ruled Brandenburg as Prince-Electors , and were subjects of the Holy Roman Emperor . Since 1618 , the Electors of Brandenburg had also ruled the Duchy of Prussia , which lay outside of the empire , in a personal union . The dual state was known as Brandenburg-Prussia . The Duchy of Prussia was originally a fief that the dukes held of the King of Poland , of whom they were vassals , until the Treaties of Labiau ( 1656 ) and Bromberg ( 1657 ) , with which Frederick William , the Great Elector , had achieved full sovereignty from the Polish Crown . In 1701 Elector Frederick III wanted to show his greatness by adopting the title king .   In return for Hohenzollern assistance in the War of the Spanish Succession and support for the Habsburg candidate in the subsequent election , Emperor Leopold I allowed Frederick to crown himself `` King in Prussia '' .   Legally , Frederick was only an elector in his domains within the borders of the empire ; he was only king in his former duchy . Even though Brandenburg was still legally part of the empire and ruled in personal union with Prussia , it soon came to be treated as a de facto part of Prussia .   On 17 January 1701 , Frederick dedicated the royal coat of arms , the Prussian black eagle with the motto `` suum cuique '' imprinted . On 18 January , he crowned himself and his wife Sophie Charlotte in a baroque ceremony in Königsberg Castle .   Even so , Frederick 's move was controversial , and only became widely accepted after the Treaty of Utrecht in 1713 . The title `` King of Prussia '' implied lordship over the entire Prussian region , not simply the former Duchy of Prussia , now Kingdom of Prussia , and the assumption of such a title by the Hohenzollern margraves would have threatened neighboring Poland ; because the province of Royal Prussia was part of the Kingdom of Poland , the Kings of Poland titled themselves Kings of Prussia until 1742 .   Throughout the 18th century the power of the Kings in Prussia continued to increase . They were victorious over the Austrian Habsburg Monarchy in the three Silesian Wars , greatly increasing their power through the acquisition of Silesia . King Frederick II adopted the title King of Prussia in 1772 , the same year he annexed most of Royal Prussia in the First Partition of Poland . The kings of Prussia continued to be Electors of Brandenburg until the empire 's dissolution in 1806 . Brandenburg was then made a province of the Kingdom of Prussia , Berlin officially gaining the status of capital of the Kingdom .

neg: Liberation of Strasbourg The Liberation of Strasbourg constituted the dramatically symbolic high point for the rehabilitation of the honor of French armed forces as the Allies advanced across France toward Germany in 1944 . Alsace , of which Strasbourg is the capital , had been the focus of French-German enmity since the Franco-Prussian War of 1870-71 , and General Charles de Gaulle insisted that only French forces should retake it . After the victory of Kufra , General Philippe Leclerc de Hauteclocque and his troops swore an oath to fight until `` our flag flies over the Cathedral of Strasbourg '' . The oath was fulfilled on 23 November 1944 , when the 2nd French Armoured Division under Leclerc 's command liberated Strasbourg .   On November 22 , 1944 , the hard-fighting French 2nd Armored Division , along with the French First Army , had been assigned the capture of Strasbourg by Allied Supreme Command . That same day , the 2nd Armored moved up to the vital pass at Saverne , which had been taken by the Americans , about 40 km northwest of Strasbourg . This Saverne `` gap '' is the historic gateway through the barrier of the Vosges Mountains , opening a line of advance on Strasbourg .   On November 23 , 1944 , units of the French 2nd Armored Division entered the city and raised the Free French tricolore over Strasbourg cathedral at 2:30 pm .   The German collective memory of the battle is rather more bleak . In Ardennes : 1944 , Antony Beevor states that the Battle for Strasbourg was one of the more `` inglorious episodes '' in German military history with a collapse of the Wehrmacht defense that was both premature and ignominious . It was hastened by a panic of senior Nazi leadership as many officials fled prior to the Allied push . This led to a general demoralization of Heer , Waffen-SS , and Luftwaffe ground forces as well as a breakdown in discipline . He states : ″ `` The SS had looted Strasbourg before withdrawing . According to one general defending the town , soldiers ordered to ` fight to the last round ' tended to throw away most of their ammunition before the battle , so they could claim that they ran out and then surrender . Generalmajor Vaterrodt , the ( Heer ) commander , was scornful about the behaviour of senior officers and Nazi Party officials . ` I 'm surprised that Himmler did not have anyone hanged in Strasbourg , ' he told fellow officers after he had been captured . ` Everyone ran away , Kreisleiter , Ortsgruppenleiter , the municipal authorities , the mayor and the deputy mayor , they all took to their heels , government officials - all fled ... ' '' . The Alsatian-born Chief Magistrate also fled towards Germany on foot with a backpack - as he had signed many death warrants and collaborated within the German occupation system and was a marked man .   Result   The rapid Liberation of Strasbourg by General LeClerc 's 2nd Armored Division produced a torrent of joy in the newly liberated French nation and was a hugely symbolic victory for the French people and the Western Allies in general . LeClerc was well respected and liked by his American contemporaries , unlike some other French commanders . The Liberation and Tricolore raised over the Cathedral was considered to be the last major objective in the Liberation of France . Unfortunately the Allies were unable to quickly seize on the German collapse . While fuel shortages and the increasing difficulty of supporting armies with lengthening supply lines played a role , General Dwight D. Eisenhower 's lack-of-interest in his southern flank largely doomed any further exploitation around Strasbourg . The commander of the American 6th Army Group , General Jacob L. Devers , believed he could cross the Rhine quickly at Rastatt thereby seizing a bridgehead . But Devers ' ambitious nature and aggressive personality somewhat alienated other commanders such as Eisenhower , and he failed to convince The Supreme Commander of his plan .   A potential bridgehead at Rastatt , had it been quickly seized , would more than likely have secured the southern flank and would have severally disrupted the coming German offensive in the Ardennes . But Eisenhower never seriously considered the opportunity as he seemed fixated on a more direct route to Berlin . As a result , Strasbourg would become threatened during the German Wacht am Rhein offensive known as The Battle of the Bulge in the West . In early January 1945 , the German counteroffensive into France known as Operation Nordwind was quickly contained , but not before both Eisenhower and Devers considered a general withdrawal from Alsace , which would have left Strasbourg undefended . The French Provisional Government considered this an anathema as it was , in General de Gaulle 's words , ( potentially ) `` a national disaster '' . In addition to this , hundreds-of-thousands of Alsatians would be subjected to German reprisals . The talk of a strategic withdrawal was also a blow to morale of the American VI Corps that had fought hard and suffered many casualties securing the area . In response General Charles de Gaulle threatened to pull his forces out of the overall SHAEF Command creating a serious row with Eisenhower . With the support of British Prime Minister Winston Churchill , de Gaulle won over Ike after a contentious argument . Strasbourg was not to be abandoned as the order to withdraw to the east of the Vosges Mountains was rescinded - boosting VI Corps ' morale . The German advance was halted in desperate fighting about 40 kilometers west of Strasbourg and Operation Norwind became another disaster for the German Heer and Waffen-SS with precious divisions reduced .

neg: German–Soviet Axis talks In October and November 1940 , German -- Soviet Axis talks occurred concerning the Soviet Union 's potential entry as a fourth Axis Power in World War II . The negotiations , which occurred during the era of the Molotov -- Ribbentrop Pact and the German-Soviet Commercial Agreement , included a two-day Berlin conference between Soviet Foreign Minister Vyacheslav Molotov , Adolf Hitler and German Foreign Minister Joachim von Ribbentrop , followed by both countries trading written proposed agreements . After two days of negotiations from 12 to 14 November 1940 , Germany presented the Soviets with a draft written Axis pact agreement defining the world spheres of influence of the four proposed Axis powers ( Japan , Germany , Soviet Union , Italy ) . Hitler , Ribbentrop and Molotov tried to set German and Soviet spheres of influence ; Hitler encouraged Molotov to look south to Iran and eventually India while preserving German access to Finland 's resources , and to remove Soviet influence in the Balkans . Molotov remained firm , seeking to remove German troops from Finland and gain a warm water port in the Balkans . Soviet foreign policy calculations were predicated by the idea that the war would be a long - term struggle and therefore German claims that Britain would be defeated swiftly were treated with scepticism . In addition Stalin sought to remain influential in Bulgaria and Yugoslavia . These factors resulted in Molotov taking a firm line . According to a Columbia University academical source , on 25 November 1940 , the Soviets presented a Stalin-drafted written counterproposal where they would accept the four power pact , but it included Soviet rights to Bulgaria and a world sphere of influence centered on the area around modern Iraq and Iran . Germany did not respond , leaving the negotiations unresolved . Regarding the counterproposal , Hitler remarked to his top military chiefs that Stalin `` demands more and more '' , `` he 's a cold-blooded blackmailer '' and that `` a German victory has become unbearable for Russia '' so that `` she must be brought to her knees as soon as possible . '' Germany ended the Molotov-Ribbentrop Pact in June 1941 by invading the Soviet Union .

neg: National Socialist Party (Romania) The National Socialist Party ( formally Nationalist-Socialist Party of Romania ; Romanian : Partidul Național-Socialist din România , PNSR ) or Steel Testudo ( Pavăza de Oțel ) was a mimetic Nazi political party , active in Romania during the early 1930s . It was led by Colonel Ștefan Tătărescu , the brother of Gheorghe Tătărescu ( twice Prime Minister of Romania during that interval ) , and existed around the newspaper Crez Nou . One of several far-right factions competing unsuccessfully against the Iron Guard for support , the group made little headway , and existed at times as a satellite of the National-Christian Defense League .   The PNSR proposed a program of corporatism and statism , promising a basic income , full employment , and limits on capitalist profits . It was anticommunist generally , and in particular anti-Soviet , circulating the theory of Jewish Bolshevism while describing its own program as the alternative , `` positive '' , socialism . The party also claimed for itself the banner of Christianity , which it associated with calls for social reorganization and the expulsion or segregation of Romanian Jews . Its Germanophilia and antisemitism were supplemented by shows of support for the policies of King Carol II .   The PNSR ' ideological stance , exotic in its Romanian context , found favor in Nazi Germany , notably from Alfred Rosenberg . Overall , the PNSR failed in its bid to establish a pan-fascist alliance in Romania , and , despite being nativist , functioned as a magnet for Transylvanian Saxons , Bessarabia Germans , and Russian émigrés . Tătărescu was received officially by his German patrons , who also provided the PNSR with funds , but eventually dropped by them for his unpopularity and alleged corruption . In late 1933 , under the antifascist Prime Minister Ion G. Duca , the party was repressed .   Tătărescu exercised some influence over his brother 's government in 1934 , helping to steer the country away from its traditional alliances , but failed in his attempt to obtain arms deals for Germany . Disavowed by both its Nazi backers and Gheorghe Tătărescu , the party moderated its stances , then disappeared from the political scene in July 1934 . Its Saxon chapter , under Fritz Fabritius , reemerged as the German People 's Party the following year .

neg: 6th SS-Standarte The 6th SS-Standarte was a regimental command of the Allgemeine-SS situated in the city of Berlin . As the command was located in the capital of Germany , the 6th Standarte was considered one of the more important SS units in Nazi Germany . The members of the Standarte themselves , however , were non-paid mustering troops of the `` General-SS '' as was the practice for most Allgemeine-SS regiments .   The Standarte was first formed in October 1931 and was part of the so-called `` Northern SS '' under the control of Kurt Daluege . At the time , there was a divisional disunity in the SS , with SS units in southern Germany controlled by Heinrich Himmler and the northern units answering to Daluege . It was not until 1934 , after most of the SS headquarters offices had relocated to Berlin , that this division was eventually done away with .   During Reichstag elections of 1931 , the 6th SS Standarte played a significant role in campaigning for the Nazi Party and repeated the effort again when Adolf Hitler ran for the office of President of Germany in 1932 . One early member of the Standarte , who would later become the Reichsführer-SS was Karl Hanke .   After Hitler became Chancellor of Germany in 1933 , the 6th SS-Standarte adopted the honor title of `` Charlottenburg '' and often participated in several major Nazi Party rallies held in the German capitol . A year later , during the Night of the Long Knives , the Standarte played a major role in rounding up the Sturmabteilung leadership in Berlin , although most SA executions were carried out by SD troops and Gestapo agents .   One of the most notorious actions that the 6th SS-Standarte engaged in was `` Kristallnacht '' where Berlin SS men sought out and destroyed numerous Jewish synagogues and businesses . Shortly afterwards , the Standarte was granted a second honor title as `` 6 SS-Standarte Eduard Felsen '' .   When World War II began in 1939 , the Berlin SS regiment slowly began losing its members to regular military service , since mustering Allgemeine-SS personnel were not exempt from conscription . The Standarte was still participating in ceremonial functions as late as 1944 , however , and in the last year of the war many of the remaining members became involved with the Volksturm and participated in the Battle of Berlin .


query: An anti-nuclear antibodies subtype is anti-nRNP antibodies.

pos: Anti-nuclear antibody Antinuclear antibodies ( ANAs , also known as antinuclear factor or ANF ) are autoantibodies that bind to contents of the cell nucleus . In normal individuals , the immune system produces antibodies to foreign proteins ( antigens ) but not to human proteins ( autoantigens ) . In some individuals , antibodies to human antigens are produced .   There are many subtypes of ANAs such as anti-Ro antibodies , anti-La antibodies , anti-Sm antibodies , anti-nRNP antibodies , anti-Scl-70 antibodies , anti-dsDNA antibodies , anti-histone antibodies , antibodies to nuclear pore complexes , anti-centromere antibodies and anti-sp100 antibodies . Each of these antibody subtypes binds to different proteins or protein complexes within the nucleus . They are found in many disorders including autoimmunity , cancer and infection , with different prevalences of antibodies depending on the condition . This allows the use of ANAs in the diagnosis of some autoimmune disorders , including systemic lupus erythematosus , Sjögren 's syndrome , scleroderma , mixed connective tissue disease , polymyositis , dermatomyositis , autoimmune hepatitis and drug induced lupus .   The ANA test detects the autoantibodies present in an individual 's blood serum . The common tests used for detecting and quantifying ANAs are indirect immunofluorescence and enzyme-linked immunosorbent assay ( ELISA ) . In immunofluorescence , the level of autoantibodies is reported as a titre . This is the highest dilution of the serum at which autoantibodies are still detectable . Positive autoantibody titres at a dilution equal to or greater than 1:160 are usually considered as clinically significant . Positive titres of less than 1:160 are present in up to 20 % of the healthy population , especially the elderly . Although positive titres of 1:160 or higher are strongly associated with autoimmune disorders , they are also found in 5 % of healthy individuals . Autoantibody screening is useful in the diagnosis of autoimmune disorders and monitoring levels helps to predict the progression of disease . A positive ANA test is seldom useful if other clinical or laboratory data supporting a diagnosis are not present .

neg: Anti-nuclear groups in the United States More than eighty anti-nuclear groups are operating , or have operated , in the United States . These include : Abalone Alliance , Clamshell Alliance , Greenpeace USA , Institute for Energy and Environmental Research , Musicians United for Safe Energy , Nevada Desert Experience , Nuclear Control Institute , Nuclear Information and Resource Service , Public Citizen Energy Program , Shad Alliance , and the Sierra Club . These are direct action , environmental , health , and public interest organizations who oppose nuclear weapons and/or nuclear power . In 1992 , the chairman of the Nuclear Regulatory Commission said that `` his agency had been pushed in the right direction on safety issues because of the pleas and protests of nuclear watchdog groups '' .   Some of the most influential groups in the anti-nuclear movement have had members who included Nobel Laureates ( e.g. , Linus Pauling and Hermann Joseph Muller ) . These scientists have belonged primarily to two groups : the Federation of American Scientists , and the Committee for Nuclear Responsibility .

neg: List of Nuclear Medicine Societies This is a list of nuclear medicine societies worldwide , mentioned in SNM and/or in EANM .   American Society of Nuclear Cardiology ( ASNC )  Armenian College of Nuclear Medicine ( ACNM )  Arab Society of Nuclear Medicine ( ARSNM )  Asia Oceania Federation of Nuclear Medicine and Biology ( AOFNMB )  Asian Regional Cooperative Council for Nuclear Medicine ( ARCCNM )  Asociación Latinoamericana de Sociedades de Biología y Medicina Nuclear ( ALASBIMN )  Associação Portuguesa de Técnicos de Medicina Nuclear ( APTMN )  Associazione Italiana di Medicina Nucleare  Australian and New Zealand Association of Physicians in Nuclear Medicine ( ANZAPNM )  Australia-New Zealand Society of Nuclear Medicine ( ANZSNM )  Austrian Society of Nuclear Medicine  Belgian Society of Nuclear Medicine ( BELNUC )  Bosnian Society of Nuclear Medicine  Brazilian Society of Biology and Nuclear Medicine  British Nuclear Medicine Society ( BNMS )  British Nuclear Cardiology Society ( BNCS )  Bulgarian Society of Nuclear Medicine  Canadian Association of Nuclear Medicine ( CANM )  Chinese Society of Nuclear Medicine ( CSNM )  Colegio Internacional de Médicos Nucleares ( ICNP ) ( Mexico )  Croatian Society of Nuclear Medicine  Cyprus Society of Nuclear Medicine  Czech Society of Nuclear Medicine ( ČSNM )  Dansk Selskab For Klinisk Fysiologi og Nuklear Medicin  Deutschen Gesellschaft für Nuklearmedizin  Dutch Society of Nuclear Medicine ( NVNG )  Egyptian Society of Nuclear Medicine Specialists ( ESNMS )  Estonian Nuclear Medicine Society ( ENMS )  European Association of Nuclear Medicine and Molecular Imaging ( EANMMI )  Finnish Society of Nuclear Medicine ( FSNM )  French Society of Nuclear Medicine  Greek Society of Nuclear Medicine and Biology  Hong Kong Society of Nuclear Medicine  Icelandic Society of Nuclear Medicine  Iranian Society of Nuclear Medicine  Irish Nuclear Medicine Association ( INMA )  Israeli Society of Nuclear Medicine ( ISNM )  Japan Society for Molecular Imaging  Japanese Society of Nuclear Medicine  Jordanian Society of Nuclear Medicine ( JOSNM )  Korean Society of Nuclear Medicine ( KSNM )  Kuwait Society of Nuclear Medicine and Molecular Imaging ( KSNMMI )  Latvian Association of Radiologist ( LRA )  Lithuanian Society of Nuclear Medicine  National Society of Nuclear Medicine of the Republic of Kazakhstan  Nigerian Association of Nuclear Medicine  Norwegian Society of Nuclear Medicine and Molecular Imaging ( NSNM )  Nuclear Cardiological Society of India ( NCSI )  Nuclear Medicine Society of Tajikistan  Pakistan Society of Nuclear Medicine ( PSNM )  Philippines National Society of Nuclear Medicine ( PSNM )  Polish Society of Nuclear Medicine  Romanian Society of Nuclear Medicine ( SRNM )  Russian Society of Nuclear Medicine ( RSNM )  Serbian Nuclear Medicine Society ( UNMS )  Slovak Society of Nuclear Medicine and Radiation Hygiene ( SSNM&RH )  Sociedade Portugesa de Medicina Nuclear ( SPMN )  Society of Nuclear Medicine and Molecular Imaging ( SNMMI )  Society of Nuclear Medicine Bangladesh  Society of Nuclear Medicine India  South African Society of Nuclear Medicine  Spanish Society of Nuclear Medicine ( SEMN )  Swedish Society of Nuclear Medicine  Swiss Society of Nuclear Medicine ( SSMN )  Tunisian Society of Nuclear Medicine ( STMN )  Turkish Society of Nuclear Medicine  Ukrainian Society of Nuclear Medicine ( USNM )  World Federation of Nuclear Medicine & Biology ( WFNMB )

neg: Autoimmune hemolytic anemia Autoimmune hemolytic anemia ( or autoimmune haemolytic anaemia ; AIHA ) occurs when antibodies directed against the person 's own red blood cells ( RBCs ) cause them to burst ( lyse ) , leading to an insufficient number of oxygen-carrying red blood cells in the circulation . The lifetime of the RBCs is reduced from the normal 100 -- 120 days to just a few days in serious cases . The intracellular components of the RBCs are released into the circulating blood and into tissues , leading to some of the characteristic symptoms of this condition . The antibodies are usually directed against high-incidence antigens , therefore they also commonly act on allogenic RBCs ( RBCs originating from outside the person themselves , e.g. in the case of a blood transfusion ) . AIHA is a relatively rare condition , affecting one to three people per 100,000 per year .   The terminology used in this disease is somewhat ambiguous . Although MeSH uses the term `` autoimmune hemolytic anemia '' , some sources prefer the term `` immunohemolytic anemia '' so drug reactions can be included in this category . The National Cancer Institute considers `` immunohemolytic anemia '' , `` autoimmune hemolytic anemia '' , and `` immune complex hemolytic anemia '' to all be synonyms .

neg: Nuclear chain cell A nuclear chain cell is a type of cell that is found in the human body .

neg: Nuclear DNA Nuclear DNA , or nuclear deoxyribonucleic acid ( nDNA ) , is the DNA contained within the nucleus of a eukaryotic organism . Nuclear DNA encodes for the majority of the genome in eukaryotes , with mitochondrial DNA and plastid DNA coding for the rest . Nuclear DNA adheres to Mendelian inheritance , with information coming from two parents , one male and one female , rather than matrilineally , as in mitochondrial DNA .

neg: HNRPU Heterogeneous nuclear ribonucleoprotein U is a protein that in humans is encoded by the HNRNPU gene .

neg: Inverse polymerase chain reaction Inverse polymerase chain reaction ( Inverse PCR ) is a variant of the polymerase chain reaction that is used to amplify DNA with only one known sequence . One limitation of conventional PCR is that it requires primers complementary to both termini of the target DNA , but this method allows PCR to be carried out even if only one sequence is available from which primers may be designed .   Inverse PCR is especially useful for the determination of insert locations . For example , various retroviruses and transposons randomly integrate into genomic DNA . To identify the sites where they have entered , the known , `` internal '' viral or transposon sequences can be used to design primers that will amplify a small portion of the flanking , `` external '' genomic DNA . The amplified product can then be sequenced and compared with DNA databases to locate the sequence which has been disrupted .   The inverse PCR method involves a series of restriction digests and ligation , resulting in a looped fragment that can be primed for PCR from a single section of known sequence . Then , like other polymerase chain reaction processes , the DNA is amplified by the temperature-sensitive DNA polymerase :   A target region with an internal section of known sequence and unknown flanking regions is identified  Genomic DNA is digested into fragments of a few kilobases by a usually low-moderate frequency ( 6-8 base ) cutting restriction enzyme .  Under low DNA concentrations , self-ligation is induced to give a circular DNA product .  PCR is carried out as usual , with primers complementary to sections of the known internal sequence . *   Finally the sequence is compared with the sequence available in the data base .   Note : although the figure suggests that the circularized ligation product is digested prior to PCR , this is not the case . PCR does not require linear products and the use of another restriction enzyme to cut the known sequence could also cut within the unknown region , resulting in a failed PCR .

neg: Nomenclature of monoclonal antibodies The nomenclature of monoclonal antibodies is a naming scheme for assigning generic , or nonproprietary , names to monoclonal antibodies . An antibody is a protein that is produced in B cells and used by the immune system of humans and other vertebrate animals to identify a specific foreign object like a bacterium or a virus . Monoclonal antibodies are those that were produced in identical cells , often artificially , and so share the same target object . They have a wide range of applications including medical uses .   This naming scheme is used for both the World Health Organization 's International Nonproprietary Names ( INN ) and the United States Adopted Names ( USAN ) for pharmaceuticals . In general , word stems are used to identify classes of drugs , in most cases placed word-finally . All monoclonal antibody names end with the stem - mab . Unlike most other pharmaceuticals , monoclonal antibody nomenclature uses different preceding word parts ( morphemes ) depending on structure and function . These are officially called substems and sometimes erroneously infixes , even by the USAN Council itself .

neg: Anti-gliadin antibodies Anti-gliadin antibodies are produced in response to gliadin , a prolamin found in wheat . In bread wheat it is encoded by three different alleles , AA , BB , and DD . These alleles can produce slightly different gliadins , which can cause the body to produce different antibodies . Some of these antibodies can detect proteins in specific grass taxa such as Triticeae ( Triticeae glutens ) , while others react sporadically with certain species in those taxa , or over many taxonomically defined grass tribes .

neg: Synactive Theory of Newborn Behavioral Organization and Development The Synactive Theory of Newborn Behavioral Organization and Development ( Synaction n. , or Synactive adj. -LSB- from the Greek syn `` together '' and the Latin actio `` action , '' resulting in : `` together in action '' -RSB- ) suggests that development of the human fetus , and later newborn , proceeds through the constant balancing of approach and avoidance behaviors , leading to : 1 ) a continuous interaction of the subsystems ( i.e. , Autonomic , Motor , State and Attention/Interaction , and Regulatory ) and their increasingly defined delineations within the organism , that is the infant , and 2 ) the organism 's interaction with the environment at large . This process is aimed at bringing about the increasingly well-defined species-unique developmental agenda .   Figure 1 ( below ) , provides a graphic representation of the Synactive Theory of development , as applied to both fetal and newborn stages . It focuses upon the infant 's within-organism , four subsystems of functioning , and their continuous interaction with each other and with the environment across time ( i.e. , `` together in action , '' or synaction ) . The four subsystems include the :   Autonomic Subsystem : Expressed in the pattern of respiration ( e.g. , fast , slow , pauses ) color changes ( e.g. , pink , pale , red ) , neurological indicators ( e.g. , seizures , tremulousness ) , and visceral or gut signals such as bowel movements , gagging , and hiccoughing ;   Motor Subsystem : Observable through the tone , posture and movement patterns of the infant ;   State and Attention/Interaction Subsystem : Expressed via : 1 ) the range of states available to the infant ( i.e. , deep sleep , light sleep , drowsy , alert , hyperalert , and cry ) , 2 ) how clearly it is to observably differentiate one state from the other , and 3 ) the patterns of transitions from one state to another ( e.g. , smooth well-differentiated state transitions versus abrupt unorganized state transitions ) .   The attention/interaction system is set within this state continuum ( i.e. , from deep sleep to cry ) and represented by the infant 's ability to adjust the robustness and increasing refinement of an alert , attentive state . The infant uses this state to take in cognitive and social information from the environment as well as to bring forth and modify inputs from the surrounding world ; and   Regulatory Subsystem : Behaviorally represented via the observable strategies the infant uses ( Self-Regulation ) in maintaining a balanced , relatively stable and relaxed state of subsystem of functioning or in returning to this a state of subsystem functioning if imbalance , or stress has occurred within the subsystems .   An additional component of the regulatory subsystem is observable in the kind and amount of support offered by the caregiver ( e.g. , supporting a soft , tucked , flexed position of the infant 's arms and legs ) or by the environment ( e.g. , dimming the lights in the nursery ) . This Co-Regulation may be necessary to help the infant 's return to balance in situations when his/her own self-regulatory capacities are exceeded .   Reproduced with permission from Als , H. Toward a synactive theory of development : Promise for the assessment of infant individuality . Infant Mental Health Journal . 1982 : ( 3 ) : 229-243 ; p. 234 .   The graphic representation of the Synactive Theory above depicts the developing organism , that is , the infant , in constant interaction with the environment from within the womb to the newborn intensive care unit ( NICU ) , and the caregiving family 's support in the NICU , to the family in their home . Newborn infants are actively striving for their next steps in development , while depending upon `` good enough '' environments and care to assure progress along their developmental agenda .   The Synactive Theory of Development continues to be instrumental in guiding clinicians ( e.g. , neonatologist , nurses , psychologists , developmental specialists , physical/occupational therapists , etc. ) and researchers in their understanding of the often very small steps in development that prematurely born and other high risk newborns attempt to accomplish ( which are major steps for their immature or injured brain ) . This theory gives professionals the framework and tools with which to identify the infant 's strengths , challenges and accomplishments . Such accomplishments may include breathing , sucking and swallowing in a coordinated sequence ; moving food down into and through the stomach and intestinal track instead of upwards , leading to reflux and vomiting ; looking at the caregiver and breathing at the same time , as well as many others .   The Synactive Theory is the foundation of both : 1 ) the Assessment of Preterm Infants ' Behavior ( APIB ) , a standardized comprehensive newborn test , and 2 ) the Newborn Individualized Developmental Care and Assessment Program ( NIDCAP ) , which is the care and intervention approach , that focuses on each infant 's behavioral cues ( e.g. , hand ( s ) to mouth , bracing with feet against a supporting surface ) in order to support the infant 's strengths and reduce the infant 's vulnerabilities . The infant 's family is viewed as the infant 's most important nurturer and is integrated in all care from the infant 's birth on throughout the infant 's hospitalization .

neg: Nuclear Physics (journal) Nuclear Physics is a peer-reviewed scientific journal published by Elsevier . The journal was established in 1956 , and then split into Nuclear Physics A and Nuclear Physics B in 1967 . A supplement series to Nuclear Physics B , called Nuclear Physics B : Proceedings Supplements has been published from 1987 onwards .   Nuclear Physics B is part of the SCOAP3 initiative .

neg: Epitope An epitope , also known as antigenic determinant , is the part of an antigen that is recognized by the immune system , specifically by antibodies , B cells , or T cells . For example , the epitope is the specific piece of the antigen to which an antibody binds . The part of an antibody that binds to the epitope is called a paratope . Although epitopes are usually non-self proteins , sequences derived from the host that can be recognized ( as in the case of autoimmune diseases ) are also epitopes .   The epitopes of protein antigens are divided into two categories , conformational epitopes and linear epitopes , based on their structure and interaction with the paratope . A conformational epitope is composed of discontinuous sections of the antigen 's amino acid sequence . These epitopes interact with the paratope based on the 3-D surface features and shape or tertiary structure of the antigen . The proportion of epitopes that are conformational is unknown .   By contrast , linear epitopes interact with the paratope based on their primary structure . A linear epitope is formed by a continuous sequence of amino acids from the antigen .

neg: Kaposi's sarcoma Kaposi 's sarcoma or Kaposi sarcoma ( -LSB- ˈkæpəʃi_sɑrˈkoʊmə -RSB- KS ) is a tumor caused by infection with human herpesvirus 8 ( HHV8 ) , also known as Kaposi sarcoma-associated herpesvirus ( KSHV ) or KS agent . It was originally described by Moritz Kaposi , a Hungarian dermatologist practicing at the University of Vienna in 1872 . It became more widely known as one of the AIDS-defining illnesses in the 1980s . The viral cause for this cancer was discovered in 1994 . Although KS is now well-established to be caused by a viral infection , there is widespread lack of awareness of this even among persons at risk for KSHV/HHV -8 infection .   Kaposi sarcoma ( KS ) is a systemic disease that can present with cutaneous lesions with or without internal involvement . Four subtypes have been described : Classic KS , affecting middle aged men of Mediterranean descent ; African endemic KS ; KS in iatrogenically immunosuppressed patients ; and AIDS-related KS . The erythematous to violaceous cutaneous lesions seen in KS have several morphologies : macular , patch , plaque , nodular , and exophytic . The cutaneous lesions can be solitary , localized or disseminated . KS can involve the oral cavity , lymph nodes , and viscera . Classic KS tends to be indolent , presenting with erythematous or violaceous patches on the lower extremities . African endemic KS and AIDS-related KS tend to be more aggressive . The AIDS-related KS lesions often rapidly progress to plaques and nodules affecting the upper trunk , face , and oral mucosa . The diagnosis can be made with a tissue biopsy and , if clinically indicated , internal imaging should be done .   Once the diagnosis of KS has been made , treatment is based on the subtype and the presence of localized versus systemic disease . Localized cutaneous disease can be treated with cryotherapy , intralesional injections of vinblastine , alitretinoin gel , radiotherapy , topical immunotherapy ( Imiquimod ) , or surgical excision . Extensive cutaneous disease or internal disease may require intravenous chemotherapy and immunotherapy . Discontinuation or reduction of immunosuppressive therapy is recommended when KS arises in the setting of iatrogenic immunosuppression . However , with AIDS-related KS , highly active antiretroviral therapy ( HAART ) has been shown to prevent , or induce regression of , KS . Some AIDS patients have complete resolution of the lesions and prolonged remission while continuing the therapy . Therefore , HAART should be considered first-line treatment for these patients , though they may require other treatments at the same time .

neg: Regavirumab Regavirumab is a human monoclonal antibody against infections with cytomegalovirus .

neg: Raji cell Raji cell line is the first continuous human cell line from hematopoietic origin . The cell lines produce an unusual strain of Epstein-Barr virus which will both transform cord blood lymphocytes and induce early antigens in Raji cells . Translocations between chromosomes 8 and 22 have occurred in all three lines , but the cells synthesize immunoglobulin M with light chains of the kappa type , in contrast to the usual concordance between a translocation involving chromosome 22 and lambda chain synthesis . Both kappa genes and one lambda gene are rearranged . These findings indicate either that translocation may occur as a separate event from immunoglobulin gene rearrangement or that the proposed hierarchical sequence of immunoglobulin gene rearrangements is not always adhered to . The data also imply that in cells containing a translocation between the long arm of chromosome 8 and a chromosome bearing an immunoglobulin gene , alteration of cellular myc expression may occur regardless of the immunoglobulin gene that is expressed . Raji cell is widely used as a transfection host and also to understand the hematopoietic and other cell malignancies . It also used for detection of immune complex because it possesses and expresses several receptors for certain complement components , as well as Fc receptors for immunoglobulin G.

neg: Plasmacytoid dendritic cell Plasmacytoid dendritic cells ( pDCs ) are innate immune cells that circulate in the blood and are found in peripheral lymphoid organs . They develop from bone marrow hematopoietic stem cells and constitute < 0.4 % of peripheral blood mononuclear cells ( PBMC ) .   In humans they exhibit plasma cell morphology and express CD4 , HLA-DR , CD123 , blood-derived dendritic cell antigen-2 ( BDCA-2 ) , Toll-like receptor ( TLR ) 7 and TLR9 within endosomal compartments , but do not express high levels of CD11c or CD14 , which distinguishes them from conventional dendritic cells or monocytes , respectively . Mouse pDC express CD11c , B220 , BST-2 / Tetherin ( mPDCA ) and Siglec-H and are negative for CD11b .   As components of the innate immune system , these cells express intracellular Toll-like receptors 7 and 9 which detect ssRNA and unmethylated CpG DNA sequences , respectively . Upon stimulation and subsequent activation , these cells produce large amounts ( up to 1,000 times more than other cell type ) of type I interferon ( mainly IFN-α ( alpha ) and IFN-β ( beta ) ) , which are critical pleiotropic anti-viral compounds mediating a wide range of effects .   The number of circulating pDCs are found to be decreased during chronic HIV infection as well as HCV infection .

neg: Supravital staining Supravital staining is a method of staining used in microscopy to examine living cells that have been removed from an organism . It differs from intravital staining , which is done by injecting or otherwise introducing the stain into the body . Thus a supravital stain may have a greater toxicity , as only a few cells need to survive it a short while . The term `` vital stain '' is used by some authors to refer specifically to an intravital stain , and by others interchangeably with a supravital stain , the core concept being that the cell being examined is still alive . As the cells are alive and unfixed , outside the body , supravital stains are temporary in nature .   The most common supravital stain is performed on reticulocytes using new methylene blue or brilliant cresyl blue , which makes it possible to see the reticulofilamentous pattern of ribosomes characteristically precipitated in these live immature red blood cells by the supravital stains . By counting the number of such cells the rate of red blood cell formation can be determined , providing an insight into bone marrow activity and anemia . This is in contrast to vital staining , when the dye employed is one that is excluded from the living cells so that only dead cells are stained positively . ( Vital stains include dyes like trypan blue and propidium iodide , which are either too bulky or too charged to cross the cell membrane , or which are actively rapidly pumped out by live cells . )   Supravital staining can be combined with cell surface antibody staining ( immunofluorescence ) for applications such as FACS analysis . Immunofluorescence can also be done within the interior of live cells by reversible cell permeabilization using the detergent Triton X-100 . Adjusted carefully to the appropriate concentration for the number of cells , the pretreatment can permit access of molecules between 1 and 150 kilodaltons to the interior of the cell . Although antibodies may be used in a similar way in this context , the term `` supravital stain '' is typically reserved for smaller chemicals which possess suitable properties intrinsically .

neg: Nuclear equivalence According to the principle of nuclear equivalence , the nuclei of essentially all differentiated adult cells of an individual are genetically ( though not necessarily metabolically ) identical to one another and to the nucleus of the zygote from which they descended . This means that virtually all somatic cells in an adult have the same genes . However , different cells express different subsets of these genes .   The evidence for nuclear equivalence comes from cases in which differentiated cells or their nuclei have been found to retain the potential of directing the development of the entire organism . Such cells or nuclei are said to exhibit totipotency .

neg: Nucleon In chemistry and physics , nucleons are the proton and the neutron , which are the constituents of the atomic nucleus , and are themselves composed of down and up quarks . The number of nucleons defines an isotope 's mass number ( nucleon number ) . The atom is made up of a nucleus surrounded by electrons .   Until the 1960s , nucleons were thought to be elementary particles , not made up of smaller parts . Now they are known to be composite particles , made of three quarks bound together by the so-called strong interaction . The interaction between two or more nucleons is called internucleon interactions or nuclear force , which is also ultimately caused by the strong interaction . ( Before the discovery of quarks , the term `` strong interaction '' referred to just internucleon interactions . )   Nucleons sit at the boundary where particle physics and nuclear physics overlap . Particle physics , particularly quantum chromodynamics , provides the fundamental equations that explain the properties of quarks and of the strong interaction . These equations explain quantitatively how quarks can bind together into protons and neutrons ( and all the other hadrons ) . However , when multiple nucleons are assembled into an atomic nucleus ( nuclide ) , these fundamental equations become too difficult to solve directly ( see lattice QCD ) . Instead , nuclides are studied within nuclear physics , which studies nucleons and their interactions by approximations and models , such as the nuclear shell model . These models can successfully explain nuclide properties , for example , whether or not a certain nuclide undergoes radioactive decay .   The proton and neutron are both baryons and both fermions . One carries a positive net charge and the other carries a zero net charge ; the proton 's mass is only 0.1 % less than the neutron 's . Thus , they can be viewed as two states of the same nucleon , and together form an isospin doublet . In isospin space , neutrons can be transformed into protons via SU ( 2 ) symmetries , and vice versa . These nucleons are acted upon equally by the strong interaction , which is invariant under rotation in isospin space . According to the Noether theorem , isospin is conserved with respect to the strong interaction .

neg: Nuclide A nuclide ( from nucleus ) is an atomic species characterized by the specific constitution of its nucleus , i.e. , by its number of protons Z , its number of neutrons N , and its nuclear energy state .   The word nuclide was proposed by Truman P. Kohman in 1947 . Kohman originally suggested nuclide as referring to a `` species of nucleus '' defined by containing a certain number of neutrons and protons . The word thus was originally intended to focus on the nucleus .


query: Bernard Madoff hired Peter, his brother, for senior managing director.

pos: Bernard Madoff Bernard Lawrence `` Bernie '' Madoff ( -LSB- ˈmeɪdɒf -RSB- born April 29 , 1938 ) is an American fraudster and a former stockbroker , investment advisor , and financier . He is the former non-executive chairman of the NASDAQ stock market , and the admitted operator of a Ponzi scheme that is considered the largest financial fraud in U.S. history . Prosecutors estimated the size of the fraud to be $ 64.8 billion , based on the amounts in the accounts of Madoff 's 4,800 clients as of November 30 , 2008 .   Madoff founded the Wall Street firm Bernard L. Madoff Investment Securities LLC in 1960 , and was its chairman until his arrest on December 11 , 2008 . The firm was one of the top market maker businesses on Wall Street , which bypassed `` specialist '' firms by directly executing orders over the counter from retail brokers . At the firm , he employed his brother Peter as senior managing director and chief compliance officer , Peter 's daughter Shana Madoff , as the firm 's rules and compliance officer and attorney , and his sons Andrew and Mark . Peter has since been sentenced to 10 years in prison and Mark committed suicide by hanging exactly two years after his father 's arrest . Andrew died of lymphoma on September 3 , 2014 .   On December 10 , 2008 , Madoff 's sons told authorities that their father had confessed to them that the asset management unit of his firm was a massive Ponzi scheme , and quoted him as describing it as `` one big lie '' . The following day , FBI agents arrested Madoff and charged him with one count of securities fraud . The U.S. Securities and Exchange Commission ( SEC ) had previously conducted multiple investigations into Madoff 's business practices , but had not uncovered the massive fraud .   On March 12 , 2009 , Madoff pleaded guilty to 11 federal felonies and admitted to turning his wealth management business into a massive Ponzi scheme . The Madoff investment scandal defrauded thousands of investors of billions of dollars . Madoff said he began the Ponzi scheme in the early 1990s . However , federal investigators believe the fraud began as early as the mid-1980s and may have begun as far back as the 1970s . Those charged with recovering the missing money believe the investment operation may never have been legitimate . The amount missing from client accounts , including fabricated gains , was almost $ 65 billion . The Securities Investor Protection Corporation ( SIPC ) trustee estimated actual losses to investors of $ 18 billion . On June 29 , 2009 , Madoff was sentenced to 150 years in prison , the maximum allowed .

neg: Lehman Brothers Treasury Lehman Brothers Treasury Co. . B.V. ( `` LBT '' ) is a private company with limited liability ( besloten vennootschap met beperkte aansprakelijkheid ) incorporated under Dutch law with its registered office in Amsterdam , the Netherlands . LBT is a fully owned subsidiary of Lehman Brothers UK Holdings ( Delaware ) Inc. , which company is fully owned by Lehman Brothers Holdings Inc. ( `` LBH '' ) . On 15 September 2008 LBH filed a petition in the United States Bankruptcy Court for the Southern District of New York seeking relief under Chapter 11 of the United States Bankruptcy Code .   On 19 September 2008 the Amsterdam District Court granted LBT provisional suspension of payment ( voorlopige surseance van betaling ) . On 8 October 2008 at 18.56 hours the Amsterdam District Court has revoked the provisional suspension of payment and declared LBT bankrupt ( in staat van faillissement ) with the appointment of Rutger Schimmelpenninck as bankruptcy trustee ( curator ) . Source : The official website of the bankruptcy trustee .

neg: Sergei Gorkov Sergei Nikolayevich Gorkov ( also tr . Sergey ; Серге́й Никола́евич Горько́в born 1 December 1968 ) is a Russian banker and attorney who is the chairman of the state-owned Vnesheconombank ( VEB ) . From 2010 -- 16 , he was the deputy chairman of Sberbank , the largest bank in Russia .   He is a graduate of the Academy of the Federal Counter-Intelligence Service , which prepares members for the Foreign Intelligence Service and Federal Security Service ( FSB ) , and has a master 's degree in economics .

neg: Tormod Hermansen Tormod Hermansen ( born 23 April 1940 ) is a former CEO of Telenor and State Secretary of Finansdepartementet ( 1978 -- 1979 ) .   His brother is Robert Hermansen .

neg: Richard Clark (business executive) Richard T. Clark is a former Chairman of the Merck & Co. ( MSD ) pharmaceutical company , a position he held from 2007 to 2011 . His previous leadership positions at Merck & Co. include CEO ( 2005 -- 2010 ) , President ( 2005 -- 2009 ) , and President of the Merck & Co. manufacturing division ( 2003 -- 2005 ) .   A first generation college student , he attended Washington & Jefferson College , where he majored in history and was a member of Lambda Chi Alpha .   He earned an MBA at the American University ( 1970 ) and was a lieutenant in the US Army 1970 -- 1972 . He was employed by Merck & Co. from 1972 .   He has served on the Washington & Jefferson College Board of Trustees .

neg: Morton E. Handel Morton E. Handel ( born 1935 ) is an American businessman who serves on the corporate board of directors and is President of S&H Consulting Ltd. , a privately held investment and consulting company , where he has been employed since 1990 .

neg: Vincent Kaminski Vincent Julian Kaminski was born in Poland and worked as the Managing Director for Research at the failed energy trading corporation Enron until 2002 . In this capacity he led a team of approximately fifty analysts who developed quantitative models to support energy trading . In the months preceding Enron 's bankruptcy Kaminski repeatedly raised strong objections to the financial practices of Enron 's Chief Financial Officer , Andrew Fastow , designed to fraudulently conceal the company 's burgeoning debt .   The primary practice involved hiding Enron 's debt in partnership companies managed by Fastow and financed by outside creditors . The debt was then secured against stock in the Enron Corporation itself , which was strongly valued at that time . To induce creditors to assume the risk of financing this debt certain `` trigger events '' were built into the contracts which would require immediate repayment of the full loan amount , such as the decline of the stock value used as collateral below a prearranged level . During the course of a company-wide comprehensive risk assessment Kaminski and his team of analysts pointed out that there existed many such arrangements , and if one were triggered the rest would be activated like dominoes as the stock price fell in response to the bad news , effectively ending the financial viability of the company . Kaminski 's strident opposition to these practices was one of the last chances to avert the implosion which soon followed .   Dr. Kaminski holds an M.S. degree in International Economics and a Ph.D. degree in Mathematical Economics from the Main School of Planning and Statistics in Warsaw ( which has since been renamed Warsaw School of Economics ) , and an MBA from Fordham University in New York City . He teaches at the business school of Rice University in Houston , Texas , and is the author of several books on risk management and energy trading . Books by Dr. Kaminski :   Energy Modelling : Advances in the Management of Uncertainty , published by Risk Books in 2005 , ISBN 1-904339-42-5   Managing Energy Price Risk : The New Challenges and Solutions , published by Risk Books in 2004 , ISBN 1-904339-19-0   Energy Markets http://riskbooks.com/energy-markets , published by Risk Books on 18 January 2013 , ISBN 9781906348793

neg: Scot J. Paltrow Scot J. Paltrow is an American journalist . A financial journalist , Paltrow currently works for Reuters .   Paltrow is from New York . He received his bachelor 's degree from the Cornell University College of Arts and Sciences and a master 's degree from the London School of Economics .   Paltrow 's journalism career began in 1977 when he joined the Memphis Commercial Appeal as a reporter . The following year , he joined the Los Angeles Herald-Examiner , where his investigative series on corruption in Industry , California , `` The City of Insiders , '' resulted in federal and state criminal probes and several convictions .   In 1981 , Paltrow moved to the Washington Star , where he covered federal courts . After the Star shut down the same year , Paltrow moved to the Wall Street Journal , where he was a reporter in the Los Angeles bureau . In 1985 , Paltrow became a European correspondent for the Journal based in Brussels . In April 1988 , Paltrow returned to the United States as New York financial bureau chief for the Los Angeles Times . During this period he did numerous investigative stories on Wall Street investment banks , markets and the insurance industry . '' While at the Times , Paltrow won a 1993 George Polk Award for Financial Reporting . Paltrow returned to the Wall Street Journal in May 1997 and served as senior special writer based in New York and writes for the paper 's Washington bureau .   In 2007 , following Rupert Murdoch 's purchase of Dow Jones & Company ( which owns the Wall Street Journal ) , Paltrow left the paper and joined Condé Nast 's Portfolio.com as a contributing editor , starting September 1 , 2007 , following another longtime Journal journalist who moved to Portfolio.com , Peter Waldman .   In September 2010 , Paltrow moved to Reuters , where he and fellow financial journalist Mark Hosenball were brought on as `` key hires '' in an effort to expand Reuters ' `` coverage of business , Wall Street and Washington . '' Paltrow joined Reuters to cover `` financial crimes , specifically covering criminal and civil investigations related to the financial crisis , as well as the effort to more closely regulate and police the financial world . '' In 2012 , Paltrow won a Society of American Business Editors and Writers Best in Business Awards in the Explanatory/News Agency category for his investigation into banks ' use of robo-signing .   Paltrow has written a report , The Case for a Stronger Federal Role in Insurance Regulation : Weak State Regulation Highlights the Need for Federal Oversight of Health Premiums , for the Center for American Progress Action Fund .   Paltrow has received a Gerald Loeb Award . Paltrow won 1992 and 1993 John Hancock Awards for Excellence in Business & Financial Journalism , the 1994 Los Angeles Times Editorial Award , the Unity Award in Media , and a 2001 Deadline Club Award from New York City Chapter of the Society of Professional Journalists .

neg: Charles Gordon (producer) Charles Gordon is an American film producer and brother to Lawrence Gordon .

neg: Boris Jordan Boris Jordan ( Борис Алексеевич Йордан , born June 2 , 1966 ) is an American businessman of Russian origin . He speaks both English and Russian fluently .   An American of Russian ancestry , Boris Jordan assisted Russia 's economic transition to capitalism in the early 1990s , assisting in the launch of the Russian stock market and the privatization of state assets . Later appointed chief executive of Russia 's Gazprom Media as well as general director of its NTV television network , Jordan was forced to resign in early 2003 under political pressure .   In 2001-2003 he was the CEO of the Russian TV channel NTV and also the CEO of Gazprom Media , a subsidiary media holding of Gazprom ( now of Gazprombank ) that owned NTV , TNT , NTV Plus , five popular radio stations ( including Echo of Moscow ) , numerous widely circulated news and entertainment publications , and two premier movie theaters in Moscow and St. Petersburg .   From 1992 to 1995 , Boris Jordan was Managing Director of the Moscow office of CS First Boston . During his tenure , CS First Boston became a leading investment bank in Russia , engaged in privatization , corporate finance and securities trading .   Boris Jordan was one of the founders of Renaissance Capital investment group ( founded in 1995 ) along with New Zealander Stephen Jennings . He is also the President and CEO of the Sputnik Group Ltd. , which he launched in 1998 . The Sputnik Group is a diversified holding company , which used to manage the Sputnik Funds , the largest foreign private-equity funds invested in Russia . Currently , The Sputnik Group owns proprietary investments in the Russian insurance ( Renaissance Insurance ) , forestry , telecommunications and media sectors -- as well as a number of investments in foreign companies .   Since 2007 Mr. Jordan is a Member of the Council on Foreign Relations and a member of The Board Of Trustees of New York University . At New York University Mr Jordan founded The Jordan Center for the Advance Center of Russia .

neg: PIMCO Pacific Investment Management Company , LLC ( commonly called PIMCO ) , is an American investment management firm headquartered in Newport Beach , California , with over 2,000 employees working in 13 offices across 12 countries , and $ 1.51 trillion in assets under management as of 30 June 2016 . The company provides mutual funds and other portfolio management and asset allocation solutions for millions of investors worldwide . PIMCO offers a broad list of investment strategies that encompass the entire risk spectrum and capital structure , including core bonds and credit , structured credit , alternatives , real assets , equities and currencies .   PIMCO oversees investments on behalf of millions of clients , including retirement savers , public and private pension plans , educational institutions , central banks and government agencies , foundations and endowments and financial intermediaries among others .   The firm , a prominent thought leader in the financial markets , is known to have coined and popularized the phrase `` The New Normal '' in the aftermath of the subprime mortgage crisis in 2009 . `` The new normal '' as a standalone phrase has a long history dating to the post-First World War era and then seeing a new resurgence in use in the post 9/11 era . More recently , PIMCO introduced `` The New Neutral '' thesis to characterize a period of lower but stable economic growth , and interest rates to remain lower than historically for a longer period of time .   In April 2015 , PIMCO announced the hire of former Federal Reserve Chairman , Dr. Ben Bernanke as a Senior Advisor , following in the footsteps of predecessor Federal Reserve Chairman , Alan Greenspan .

neg: Bloomberg L.P. Bloomberg L.P. is a privately held financial software , data , and media company headquartered in Midtown Manhattan , New York City . Bloomberg L.P. was founded by Michael Bloomberg in 1981 with the help of Thomas Secunda , Duncan MacMillan , Charles Zegar , and a 30 % ownership investment by Merrill Lynch .   Bloomberg L.P. provides financial software tools such as an analytics and equity trading platform , data services , and news to financial companies and organizations through the Bloomberg Terminal ( via its Bloomberg Professional Service ) , its core revenue-generating product . Bloomberg L.P. also includes a wire service ( Bloomberg News ) , a global television network ( Bloomberg Television ) , digital websites , a radio station ( WBBR ) , subscription-only newsletters , and three magazines : Bloomberg Businessweek , Bloomberg Markets , and Bloomberg Pursuits . In 2014 , Bloomberg L.P. launched Bloomberg Politics , a multiplatform media property that merged the company 's political news teams , and has recruited two veteran political journalists , Mark Halperin and John Heilemann , to run it .

neg: Romano Scavolini Romano Scavolini ( born 18 June 1940 ) is an Italian film director , brother of Sauro Scavolini .

neg: William Shaw (businessman) William J. Shaw is the Vice-Chairman of Marriott International Inc. . He has held this post since May 2009 . Shaw received his BA from University of Notre Dame and MBA from Washington University in St. Louis in 1972 . He joined the Marriott hotel company in 1974 , was elected Corporate Controller in 1979 , and a company Vice President in 1982 . In 1986 , Shaw became Senior Vice President of Finance and Treasurer of Marriott Corporation . He was elected Chief Financial Officer and Executive Vice President of Marriott Corporation in April 1988 . In February 1992 , he was elected President of the Marriott Service Group . Between March 1997 and April 2009 , Shaw served as the President and Chief Operating Officer of Marriott International , before taking up his current position as Vice-Chairman .   Mr. Shaw is on the board of trustees of the University of Notre Dame , the Suburban Hospital Foundation , the Wolf Trap Foundation of the Performing Arts , Washington Mutual Investor Fund , board of directors and the NCAA Leadership Advisory Board . Mr. Shaw has been a director of Marriott International , or its predecessors , since 1997 , and is currently serving a term expiring at the 2008 annual meeting of shareholders .

neg: Guggenheim Partners Guggenheim Partners is a global investment and advisory financial services firm that engages in investment banking , capital markets services , investment management , investment advisory , and insurance services . The firm is headquartered in New York City and Chicago with 2,300 staff located in 20 cities throughout the United States , Europe , and Asia . It has more than $ 260 billion of assets under management . The firm 's CEO is Mark Walter . It has six Managing Partners who are key executives , and with a Senior Leadership Team of 17 other executives , oversee the Firm 's businesses . It was founded by Peter Lawson-Johnston II , Solomon R. Guggenheim 's great-grandson .

neg: Frank Popoff Frank Popoff or Frank Popov ( Франк Попов born 1935 in Sofia , Kingdom of Bulgaria ) is a Bulgarian American businessman . He has served as the Chairman of Chemical Financial Corporation since April 2004 .

neg: Peter Wallenberg, Jr. Peter Åke `` Poker '' Wallenberg , Jr. ( born 8 May 1959 ) is a Swedish businessman and racing driver . He is Director of Investor , Atlas Copco and Scania , and chairman of the Knut and Alice Wallenberg Foundation   He took an in International Bachaloria from Leysin American School in Leysin , Switzerland and graduated with a BSBA in Hotel Administration from University of Denver .   He has also been driving in the Porsche Carrera Cup Scandinavia .   Peter Wallenberg , Jr. is the youngest son of Peter Wallenberg , Sr. ( 1926-2015 ) .

neg: Bart McDade Herbert `` Bart '' H. McDade III was the President and COO of Lehman Brothers at the time of its bankruptcy . During the end of Lehman 's existence , McDade was tasked with largely running the firm and saving it as the then CEO , Richard Fuld was largely sidelined .

neg: Michael Polcino Michael Polcino is an animation director on The Simpsons . His brother , Dominic Polcino , is a former Simpsons director and currently works on Family Guy .

neg: Kenneth Frazier Kenneth Carleton Frazier ( born ) is an American business executive . He is the chairman and CEO of the pharmaceutical company Merck & Co. ( known as MSD outside of North America ) . After joining Merck & Co. as general counsel , he directed the company 's defense against litigation over the anti-inflammatory drug Vioxx . Frazier is the second African-American to lead a major pharmaceutical company .

neg: Stefano Siragusa Stefano Siragusa ( born January 29 , 1976 ) , is an Italian business executive . He is currently Senior Partner and Managing Director of Bain & Company .