query: Bangladesh is a nation.

pos: Bangladesh Bangladesh ( -LSB- bæŋɡləˈdɛʃ -RSB- -LSB- ˌbɑːŋɡləˈdɛʃ -RSB- -LSB- : bn : বাংলাদেশ , বাংলাদেশ -RSB- , -LSB- ˈbaŋlad̪eʃ -RSB- , lit . `` The country of Bengal '' ) , officially the People 's Republic of Bangladesh , is a country in South Asia . It shares land borders with India and Myanmar ( Burma ) . Nepal , Bhutan and China are located near Bangladesh but do not share a border with it . The country 's maritime territory in the Bay of Bengal is roughly equal to the size of its land area . Bangladesh is the world 's eighth most populous country . Dhaka is its capital and largest city , followed by Chittagong , which has the country 's largest port .   Bangladesh forms the largest and eastern part of the Bengal region . Bangladeshis include people of different ethnic groups and religions . Bengalis , who speak the official Bengali language , make up 98 % of the population . The politically dominant Bengali Muslims make the nation the world 's third largest Muslim-majority country . Most of Bangladesh is covered by the Bengal delta , the largest delta on Earth . The country has 700 rivers and 8,046 km ( 5,000 miles ) of inland waterways . Highlands with evergreen forests are found in the northeastern and southeastern regions of the country . Bangladesh has many islands and a coral reef . It is home to the Sundarbans , the largest mangrove forest in the world . The country 's biodiversity includes a vast array of plant and wildlife , including critically endangered Bengal tigers , the national animal .   The Greeks and Romans identified the region as Gangaridai , a powerful kingdom of the historical subcontinent , in the 3rd century BCE . Archaeological research has unearthed several ancient cities in Bangladesh , which had international trade links for millennia . The Bengal Sultanate and Mughal Bengal transformed the region into a cosmopolitan Islamic imperial power between the 14th and 18th centuries . The region was home to many principalities that had inland naval prowess . It was also a notable center of the worldwide muslin and silk trade . As part of British India , the region was influenced by the Bengali renaissance and played an important role in anti-colonial movements . The Partition of British India made East Bengal a part of the Dominion of Pakistan ; and was renamed as East Pakistan . The region witnessed the Bengali Language Movement in 1952 and the Bangladesh Liberation War in 1971 . After independence , a parliamentary republic was established . A presidential government was in place between 1975 and 1990 , followed by a return to parliamentary democracy . The country has also been affected by poverty , natural disasters , hunger , dominant party systems and military coups .   Bangladesh is a middle power and a major developing nation . Within South Asia , the country ranks first in gender equality , second in foreign exchange earnings and third in life expectancy and peacefulness . Listed as one of the Next Eleven , its economy ranks 46th in terms of nominal gross domestic product ( GDP ) and 29th in terms of purchasing power parity ( PPP ) . It is one of the largest textile exporters in the world . Its major trading partners are the European Union , the United States , China , India , Japan , Malaysia and Singapore . With its strategically vital location between Southern , Eastern and Southeast Asia , Bangladesh is an important promoter of regional connectivity and cooperation . It is a founding member of SAARC , BIMSTEC , the Bangladesh-China-India-Myanmar Forum for Regional Cooperation and the Bangladesh Bhutan India Nepal Initiative . It is also a member of the Commonwealth of Nations , the Developing 8 Countries , the OIC , the Non Aligned Movement , the Group of 77 and the World Trade Organization . Bangladesh is one of the largest contributors to United Nations peacekeeping forces .

neg: Wards of Bangladesh In Bangladesh , a ward is an optional division of a city or town , especially an electoral district , for administrative and representative purposes . It is an elective unit of a City Corporation or Municipal Corporation , created for the purpose of providing more direct representation , from which a single council member is elected .

neg: Indigenous peoples in Bangladesh The indigenous peoples of Bangladesh refer to native ethnic minorities in southeastern , northwestern , north-central and northeastern regions of the country . These regions include the Chittagong Hill Tracts , Sylhet Division , Rajshahi Division and Mymensingh District . The total population of indigenous ethnic minorities in Bangladesh was estimated to be over 2 million in 2010 . They are diverse ethnic communities including Australoid , Tibeto-Burman and Sino-Tibetan races . Vast number of indigenous tribes of Bangladesh are Buddhists and Hindus by faith while the remaining few are Christians and animists .

neg: Bangladesh–North Korea relations Bangladesh -- North Korea relations refer to the bilateral relations between Bangladesh and North Korea .

neg: History of Bangladeshis in the United Kingdom Bangladeshis are one of the largest immigrant communities in the United Kingdom . Significant numbers of ethnic Bengali and ethnic Sylheti peoples arrived as early as the 17th century , mostly as lascar seamen working on ships . Following the founding of Bangladesh in 1971 , a large immigration to Britain took place during the 1970s , leading to the establishment of a British Bangladeshi community . Bangladeshis were encouraged to move to Britain during that decade because of changes in immigration laws , natural disasters such as the Bhola cyclone , the Bangladesh Liberation War against Pakistan , and the desire to escape poverty , and the perception of a better living led Sylheti men bringing their families.Murshid , Ghulam . 2008 . The call of the sea : History of Bangali in Britain -LSB- in Bengali : Kalapanir hatchani : Bilete  Bangaleer itihash -RSB- ( Dhaka , Abosar ) . During the 1970s and 1980s , they experienced institutionalised racism and racial attacks by organised ultra-right fascist groups such as National Front and British Nationalist Party .

neg: Bengali vocabulary Bengali ( বাংলা Bangla ) is one of the Magadhan languages , evolved from Magadhi Prakrit and Pali languages . The core of Bengali vocabulary is thus etymologically of Magadhi Prakrit and Pali languages . However , centuries of major borrowing and reborrowing from Arabic , Persian , Turkish , Sanskrit , Austroasiatic languages and other languages has led to the adoption of a wide range of words with foreign origins . Thus making the origins of borrowed and reborrowed words in the Bengali vocabulary numerous and diverse , due to centuries of contact with various languages .

neg: Bangladesh Rural Development Board Bangladesh Rural Development Board or BRDB , is a government board responsible for the development in rural areas and is largest government program involved in rural development in Bangladesh and is located in Dhaka , Bangladesh .

neg: Stranded Pakistanis in Bangladesh Stranded Pakistanis in Bangladesh ( -LSB- , উদ্বাস্তু পাকিস্তানী ) are Urdu-speaking Muslim migrants with homelands in present-day India and Pakistan who settled in East Pakistan ( now Bangladesh ) following the partition of India in 1947 .   This identification can encompass several groups of people . First among them is `` Bihari Muslims '' . Although most of this population belonged to State of Bihar in India there are many from other Indian states such as U.P. ( United Provinces or later Uttar Pradesh ) . There are still others who had settled in what is now known as Bangladesh in the late 19th century . The second term of reference for this group coined by themselves after creation of Bangladesh is `` Stranded Pakistanis '' . In Urdu media in Pakistan and elsewhere this was translated as `` Mehsooreen '' or the `` Besieged '' . Another common term is `` Non-Bengalis '' , which includes not only the Urdu-speaking but also Punjabis , Pathans and Baloch living in Bangladesh . Henceforth any of the above terms may be used to identify this group depending on the context and history .   Biharis were stateless until 2008 when a judgement by the Dhaka High Court gave them right of citizenship . The judgement does not cover refugees who were adults at the time of Bangladesh Liberation War .   In March 2015 , Ministry of Foreign Affairs of Pakistan said that more than 170,000 Biharis had been repatriated to Pakistan and the remaining ` stranded Pakistanis ' are not its responsibility but rather the responsibility of Bangladesh .

neg: Sher-e-Bangla (disambiguation) Sher-e-Bangla , from the Urdu meaning `` Tiger of Bengal '' , may refer to :   A.K. Fazlul Huq , Bangladeshi statesman in whose honor several institutions and places have been named  Sher-e-Bangla Nagor , a neighborhood in Dhaka , named after Huq  Sher-e-Bangla Cricket Stadium , named after Huq  Sher-e-Bangla Agricultural University , named after Huq  Sher-e-Bangla Medical College , named after Huq

neg: Bangladeshi (disambiguation) Bangladeshi may refer to :

neg: International Crimes Tribunal (Bangladesh) The International Crimes Tribunal ( Bangladesh ) ( ICT of Bangladesh ) is a domestic war crimes tribunal in Bangladesh set up in 2009 to investigate and prosecute suspects for the genocide committed in 1971 by the Pakistan Army and their local collaborators , Razakars , Al-Badr and Al-Shams during the Bangladesh Liberation War . During the 2008 general election , the Awami League ( AL ) pledged to establish the tribunals in response to long-standing calls for trying war criminals . The first indictments were issued in 2010 . However , the main perpetrators of the war crimes , the Pakistan soldiers , remained out of the reach of the courts .   The government set up the tribunal after the Awami League won the general election in December 2008 with a more than two-thirds majority in parliament . The War Crimes Fact Finding Committee , tasked to investigate and find evidence , completed its report in 2008 , identifying 1,600 suspects . Prior to the formation of the ICT , the United Nations Development Programme offered assistance in 2009 on the tribunal 's formation . In 2009 , the parliament amended the 1973 act that authorised such a tribunal to update it .   By 2012 , nine leaders of Jamaat-e-Islami , the largest Islamist party in the nation , and two of the Bangladesh Nationalist Party , had been indicted as suspects in war crimes . Three leaders of Jamaat were the first tried ; each were convicted of several charges of war crimes . The first person convicted was Abul Kalam Azad , tried in absentia as he had left the country ; he was sentenced to death in January 2013 .   The ICT initially received some offers of international assistance . In 2009 , the UN offered its expertise , expressing an interest in helping Bangladesh avoid the problems other countries faced in similar trials . The EU has passed three resolutions supporting the trials and Jean Lambert has said `` she expected that the trial would conform to the highest standard possible . ''   However , since the beginning of the trials several human rights organisations and international legal figures have raised objections to the court proceedings . Human Rights Watch , which initially supported the establishment of the tribunal , have criticised it for issues of fairness and transparency , as well as reported harassment of lawyers and witnesses representing the accused . Bianca Karim and Tirza Theunissen have written that the international community have voiced concerns that the trial will not be transparent or impartial .   Jamaat-e-Islami supporters and their student wing , Bangladesh Islami Chhatra Shibir , called a general strike nationwide on 4 December 2012 , which erupted in violence . The group demanded the tribunal be scrapped permanently and their leaders be released immediately .   Annual public opinion polls regularly rank the war-crimes trials ranked among the top three `` positive steps that the government has taken '' , though the issue is not considered among the top ten most pressing issues facing the country . Polling in 2013 by AC Nielsen found that more than two-thirds of Bangladeshis characterise the ICT as `` unfair '' or `` very unfair '' , though 86 % support its implementation .   In February 2013 , Abdul Quader Molla , Assistant Secretary General of Jamaat , was the first person sentenced to death by the ICT who was not convicted in absentia . Initially , Molla was sentenced to life imprisonment , but demonstrations , including the 2013 Shahbag protests in Dhaka , lead to a new punishment .

neg: List of television stations in Bangladesh The first television signal broadcast in Bangladesh was in 1964 by the then state-owned television network Pakistan Television Corporation ( PTV ) . From then onwards Bangladesh Television ( BTV ) had a virtual monopoly until the late 1990s . Since then a number of stations have arrived . Many have also shut down in the process .   This is a list of television stations in Bangladesh available on digital terrestrial , satellite and cable systems .   Public service broadcasters  BTV -- state-owned , founded in 1964 as Pakistan Television , but renamed BTV after 1971 .  BTV World -- state-owned , available worldwide .  Sangsad Television -- broadcasts live scenarios of Bangladesh 's politics and also live telecasts National Parliament Assemblies .

neg: Bengali Christians Bengali Christians also known as Firingis , are adherents of Christianity among the Bengali people . They speak the Bengali language and are native to Bangladesh and the Indian state of West Bengal . The majority of Bengali Christians are Roman Catholics .   Christianity took root in Bengal after the arrival of Portuguese voyagers in the 16th century . It witnessed further conversions among the Bengali elite during the 19th century Bengali renaissance .   Bengali Christians have made significant contributions to Bengali culture , commerce and society . The region is home to venerable Christian missionary institutions , including the Missionaries of Charity founded by Mother Teresa .

neg: Bangladeshi rock Bangladeshi rock or Bangla rock is the rock music of Bangladesh . It originated in Chittagong with Souls , which was formed in 1970 . Distortion , electric and bass guitars and drums are used , sometimes accompanied by piano or other keyboard instruments . In the past , it was accompanied by saxophone , flute , violin and bass violin .

neg: Sikhism in Bangladesh Sikhism in Bangladesh dates back to 1503 but has declined after the partition . Most of the sikhs in the country are officials of Indian High Commission or pilgrims . Some estimates shows that there are 23,000 to 100,000 Sikhs in Bangladesh but Bangladeshi Sikhs are very rare . There were eighteen historical Gurdwara 's in Bangladesh but now only Seven are left .

neg: Bangladesh Olympic Association Bangladesh Olympic Association ( বাংলাদেশ অলিম্পিক সংস্থা IOC code : BAN ) is the National Olympic Committee representing Bangladesh . It is also the body responsible for Bangladesh 's representation at the Commonwealth Games .

neg: Bangladesh–Cyprus relations Bangladesh -- Cyprus relations refer to the bilateral relations between Bangladesh and Cyprus . Neither country has a resident ambassador . Both the countries are members of Non-Aligned Movement , Commonwealth of Nations Relations between the two countries have remained cordial with both the countries showing willingness to strengthen it further .

neg: Stateless nation Stateless nation is a political term for ethnic/national minority that does not possess its own state and is not the majority population in any nation state . The term implies that the group `` should have '' such a state . Members of stateless ethnic groups may be citizens/nationals of the country in which they live , or they may be denied citizenship by that country . Stateless nations are usually not represented as a nation in international sports such as FIFA , Olympics or in international communities such as the United Nations . Nations without state are classified as fourth world nations . Some of the stateless nations have a great heritage and a long tradition of statehood in the past and some were always a stateless nation , which was dominated by another nation for a large part of its history .   Stateless nations either are dispersed across a number of states ( for example , the Yoruba people are found in the African states of Nigeria , Benin and Togo ) or form the native population of a province within a larger state ( such as the Uyghur people in the Xinjiang Uyghur Autonomous Region within the People 's Republic of China ) . Some stateless nations historically had a state , which was absorbed by another ; for example , Tibet 's declaration of independence in 1913 was not recognized , and it was invaded in 1951 by the People 's Republic of China which claims that Tibet is an integral part of China , while the Tibetan government-in-exile maintains that Tibet is an independent state under unlawful occupation . Some ethnic groups were once a stateless nation that later became a nation state ( for example , the nations of the Balkans such as the Croats , Serbs , Bosniaks , Slovenes , Montenegrins , Kosovars and Macedonians were once part of a multinational state of Yugoslavia . Since the breakup of Yugoslavia many nation states were formed ) .   Stateless nations can have large population . For example , The Tamils are a stateless nation in South Asia with a population of more than 70 million . They form one of the largest ethnic groups in South India . Governments may respond differently on stateless nations in their states . For example , the suppression of the Tamil people in Sri Lanka led to one of the longest and most violent separatist conflict between 1983 and 2009 . However , a similar ethnic conflict was absent among Tamils in India during this period , because they were peacefully integrated into the federal structure of India . Multiple stateless nations can reside in the same region . For example , Catalans , Basques , Aragonese , Galicians , Asturians , Valencians , Andalusians in Iberian Peninsula or the Brahui , Santhals and Balochs in South Asia .   The Romani people are another stateless people . They may be a special case being distributed among numerous countries with no clear homeland ; as a traditionally `` nomadic '' people , the Romani/Roma are a classical `` stateless nation '' without aspiration to sovereign territory . As not all states are nation states , there are a number of ethnic groups who live in a multinational state without being considered `` stateless nations '' .

neg: International recognition of Bangladesh The Bangladesh Liberation War ( মুক্তিযুদ্ধ Muktijuddho ) was a revolutionary independence war in South Asia during 1971 which established the republic of Bangladesh . The war pitted East Pakistan against West Pakistan , and lasted over a duration of nine months . It witnessed large-scale atrocities , the exodus of 10 million refugees and the displacement of 30 million people .   The war broke out on 26 March 1971 , when the Pakistani Army launched a military operation called Operation Searchlight against Bengali civilians , students , intelligentsia and armed personnel , who were demanding that the Pakistani military junta accept the results of the 1970 first democratic elections of Pakistan , which were won by an eastern party , or to allow separation between East and West Pakistan . Bengali politicians and army officers announced the declaration of Bangladesh 's independence in response to Operation Searchlight . Bengali military , paramilitary and civilians formed the Mukti Bahini ( মুক্তি বাহিনী `` Liberation Army '' ) , which engaged in guerrilla warfare against Pakistani forces . The Pakistan Army , in collusion with religious extremist militias ( the Razakars , Al-Badr and Al-Shams ) , engaged in the systematic genocide and atrocities of Bengali civilians , particularly nationalists , intellectuals , youth and religious minorities . Bangladesh government-in-exile was set up in the city of Calcutta ( now Kolkata ) in the Indian State of West Bengal .   India entered the war on 3 December 1971 , after Pakistan launched pre-emptive air strikes on northern India . Overwhelmed by two war fronts , Pakistani defences soon collapsed . On 16 December , the Allied Forces of Bangladesh and India defeated Pakistan in the east . The subsequent surrender resulted in the largest number of prisoners-of-war since World War II .

neg: Bangladesh–Thailand relations Bangladesh -- Thailand relations refer to foreign relations between Bangladesh and Thailand . Relations were established on 5 October 1972 . Thailand opened its embassy in Bangladesh in 1974 , and Bangladesh opened its embassy in Bangkok in 1975 .

neg: Goalpara region Goalpara region , largely congruous to the historical undivided Goalpara district , is a region that is associated with the people and culture of Goalpara . It is bounded on the north by Bhutan , on the east by the Kamrup region , in the south by Meghalaya and in the west by Cooch Behar and Jalpaiguri in West Bengal and Rangpur in Bangladesh . The natural landmarks are : Sankosh and Brahmaputra rivers on the west , the Manas river on the east in the north bank , and a corresponding region in the south bank ; the Garo Hills in the south and Bhutan Hills in the north .


query: Shingles is more common among older people.

pos: Shingles Shingles , also known as herpes zoster , is a viral disease characterized by a painful skin rash with blisters in a localized area . Typically the rash occurs in a single stripe either on the left or right of the body or face . Two to four days before the rash occurs there may be tingling or local pain in the area . Otherwise there are typically few symptoms . The rash usually heals within two to four weeks ; however , some people develop ongoing nerve pain which can last for months or years , a condition called postherpetic neuralgia . In those with poor immune function the rash may occur widely . If the rash involves the eye , vision loss may occur .   Shingles is due to a reactivation of varicella zoster virus ( VZV ) within a person 's body . Chickenpox is due to an initial infection with VZV . Once chickenpox has resolved , the virus may remain inactive in nerve cells . When it reactivates it travels from the nerve body to the endings in the skin producing blisters . Risk factors for reactivation include old age , poor immune function , and having had chickenpox before 18 months of age . How the virus remains in the body or subsequently re-activates is not well understood . Exposure to the virus in the blisters can cause chickenpox in someone who has not had it before but will not trigger shingles . Diagnosis is typically based on a person 's signs and symptoms . Varicella zoster virus is not the same as herpes simplex virus ; however , they belong to the same family of viruses .   The shingles vaccine decreases the chance of shingles by about half in those between the ages of 50 and 80 . It also decreases rates of postherpetic neuralgia , and if an outbreak occurs , its severity . After 80 the vaccine is still effective , just less so . It contains the same material as the varicella vaccine , just at a higher dose . If shingles develops , antiviral medications such as aciclovir can reduce the severity and duration of disease if started within 72 hours of the appearance of the rash . Evidence does not show a significant effect of antivirals or steroids on rates of postherpetic neuralgia . Paracetamol , NSAIDs , or opioids may be used to help with the acute pain .   It is estimated that about a third of people develop shingles at some point in their life . While more common among older people , children may also get the disease . The number of new cases per year ranges from 1.2 -- 3.4 per 1,000 among healthy individuals to 3.9 -- 11.8 per 1,000 among those older than 65 years of age . About half of those living to age 85 will have at least one attack , and less than 5 % will have more than one attack . The disease has been recognized since ancient times .

neg: Chronic fatigue syndrome treatment Treatment of chronic fatigue syndrome ( CFS ) is variable and uncertain , and the condition is primarily managed rather than cured . Only two treatments , cognitive behavioral therapy and graded exercise therapy , have demonstrated reproducible evidence for their efficacy people with CFS who are walking . There are no Food and Drug Administration ( FDA ) approved medications for ME/CFS treatment , although medications are used without approval for the illness ( off-label ) . Drugs have been used in experimental studies of the illness that have n't been approved for market for any condition in the United States ( for example , isoprinosine and rintatolimod ) . Other proposed treatments include medical treatments and alternative medicine . Even when treated , the prognosis of CFS is often poor . In one study , poor early management was reported to be a main risk factor for severe CFS ( delayed diagnosis , poor response to analgesics , physiotherapy , or alternative medicine ) , with associated variables including a poor relationship with the GP before and after diagnosis , and the involvement of a psychiatrist in initial treatment .   CFS management techniques include behavioral interventions such as cognitive behavioral therapy ( CBT , a form of psychological therapy ) , and graded exercise therapy ( GET ) . Based on evidence from multiple randomized clinical trials ( RCTs ) , a systematic review published in the Journal of the Royal Society of Medicine ( October 2006 ) stated that CBT and GET interventions showed promising results , appearing to reduce symptoms and improve function . The review stated that the evidence of effectiveness was inconclusive for most other interventions , with some reporting significant adverse effects . The wide variety of outcome measures used in CFS research was found to be a `` fundamental problem '' for assessing the effectiveness of interventions in general , and no intervention has proven to be effective in restoring the ability to work .   Recovery is `` rare '' even after a comprehensive rehabilitation programme .

neg: Glaucoma Glaucoma is a group of eye diseases which result in damage to the optic nerve and vision loss . The most common type is open-angle glaucoma with less common types including closed-angle glaucoma and normal-tension glaucoma . Open-angle glaucoma develops slowly over time and there is no pain . Side vision may begin to decrease followed by central vision resulting in blindness if not treated . Closed-angle glaucoma can present gradually or suddenly . The sudden presentation may involve severe eye pain , blurred vision , mid-dilated pupil , redness of the eye , and nausea . Vision loss from glaucoma , once it has occurred , is permanent .   Risk factors for glaucoma include increased pressure in the eye , a family history of the condition , migraines , high blood pressure , and obesity . For eye pressures a value of greater than 21 mmHg is often used with higher pressures leading to a greater risk . However , some may have high eye pressure for years and never develop damage . Conversely , optic nerve damage may occur with normal pressure , known as normal-tension glaucoma . The mechanism of open-angle glaucoma is believed to be slow exit of aqueous humor through the trabecular meshwork while in closed-angle glaucoma the iris blocks the trabecular meshwork . Diagnosis is by a dilated eye examination . Often the optic nerve shows an abnormal amount of cupping .   If treated early it is possible to slow or stop the progression of disease with medication , laser treatment , or surgery . The goal of these treatments is to decrease eye pressure . A number of different classes of glaucoma medication are available . Laser treatments may be effective in both open-angle and closed-angle glaucoma . A number of types of glaucoma surgeries may be used in people who do not respond sufficiently to other measures . Treatment of closed-angle glaucoma is a medical emergency .   About 6 to 67 million people have glaucoma globally . The disease affects about 2 million people in the United States . It occurs more commonly among older people . Closed-angle glaucoma is more common in women . Glaucoma has been called the `` silent thief of sight '' because the loss of vision usually occurs slowly over a long period of time . Worldwide , glaucoma is the second-leading cause of blindness after cataracts . The word `` glaucoma '' is from ancient Greek glaukos which means blue , green , or gray . In English , the word was used as early as 1587 but did not become commonly used until after 1850 , when the development of the ophthalmoscope allowed people to see the optic nerve damage .

neg: Poliomyelitis Poliomyelitis , often called polio or infantile paralysis , is an infectious disease caused by the poliovirus . In about 0.5 percent of cases there is muscle weakness resulting in an inability to move . This can occur over a few hours to a few days . The weakness most often involves the legs but may less commonly involve the muscles of the head , neck and diaphragm . Many but not all people fully recover . In those with muscle weakness about 2 to 5 percent of children and 15 to 30 percent of adults die . Another 25 percent of people have minor symptoms such as fever and a sore throat and up to 5 percent have headache , neck stiffness and pains in the arms and legs . These people are usually back to normal within one or two weeks . In up to 70 percent of infections there are no symptoms . Years after recovery post-polio syndrome may occur , with a slow development of muscle weakness similar to that which the person had during the initial infection .   Poliovirus is usually spread from person to person through infected fecal matter entering the mouth . It may also be spread by food or water containing human feces and less commonly from infected saliva . Those who are infected may spread the disease for up to six weeks even if no symptoms are present . The disease may be diagnosed by finding the virus in the feces or detecting antibodies against it in the blood . The disease only occurs naturally in humans .   The disease is preventable with the polio vaccine ; however , a number of doses are required for it to be effective . The US Centers for Disease Control and Prevention recommends polio vaccination boosters for travelers and those who live in countries where the disease is occurring . Once infected there is no specific treatment . In 2016 , polio affected 42 people , while there were about 350,000 cases in 1988 . In 2014 the disease was only spreading between people in Afghanistan , Nigeria , and Pakistan . In 2015 Nigeria had stopped the spread of wild poliovirus but it reoccurred in 2016 .   Poliomyelitis has existed for thousands of years , with depictions of the disease in ancient art . The disease was first recognized as a distinct condition by Michael Underwood in 1789 and the virus that causes it was first identified in 1908 by Karl Landsteiner . Major outbreaks started to occur in the late 19th century in Europe and the United States . In the 20th century it became one of the most worrying childhood diseases in these areas . The first polio vaccine was developed in the 1950s by Jonas Salk . It is hoped that vaccination efforts and early detection of cases will result in global eradication of the disease by 2018 .

neg: Acrochordon An acrochordon ( plural acrochorda ; also known as a skin tag or fibroepithelial polyp ) is a small benign tumor that forms primarily in areas where the skin forms creases , such as the neck , armpit , and groin . They may also occur on the face , usually on the eyelids . Acrochorda are harmless , are typically painless and usually do not grow or change over time . Though tags up to a half-inch long have been seen , they are typically the size of a grain of rice . The surface of an acrochordon may be smooth or irregular in appearance and is often raised from the surface of the skin on a fleshy stalk called a peduncle . Microscopically , an acrochordon consists of a fibrovascular core , sometimes also with fat cells , covered by an unremarkable epidermis . However , tags may become irritated by shaving , clothing , jewellery , or eczema .   Skin tags are thought to occur from skin rubbing up against skin , since they are so often found in skin creases and folds . Studies have shown existence of low-risk HPV 6 and 11 in skin tags , hinting at a possible role in its pathogenesis . Acrochorda have been reported to have a prevalence of 46 % in the general population . A causal genetic component is thought to exist . They also are more common in women than in men . Rarely , they can be associated with the Birt -- Hogg -- Dubé syndrome , acromegaly , and polycystic ovary syndrome .   Skin tags may serve as a marker for those people whose carbohydrate metabolism is impaired and for those who may be at risk for diabetes mellitus type 2 , although such a link has not been shown . Elevated blood sugar and insulin increase the incidence of skin tags through an unknown mechanism .

neg: Epidemiology of syphilis Syphilis is believed to have infected people in 1999 with greater than 90 % of cases in the developing world . It affects between 700,000 and 1.6 million pregnancies a year resulting in spontaneous abortions , stillbirths , and congenital syphilis . In Sub-Saharan Africa syphilis contributes to approximately 20 % of perinatal deaths .   In the developed world , syphilis infections were in decline until the 1980s and 1990s due to widespread use of antibiotics . Since the year 2000 , rates of syphilis have been increasing in the US , UK , Australia , and Europe primarily among men who have sex with men . This is attributed to unsafe sexual practices .   Increased rates among heterosexuals have occurred in China and Russia since the 1990s . Syphilis increases the risk of HIV transmission by two to five times and co-infection is common ( 30 -- 60 % in a number of urban centers ) .   Untreated it has a mortality of 8 % to 58 % with a greater death rate in males . The symptoms of syphilis have become less severe over the 19th and 20th century in part due to widespread availability of effective treatment and partly due to decreasing virulence of the spirochete . With early treatment few complications result .

neg: Parkinson's disease Parkinson 's disease ( PD ) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system . The symptoms generally come on slowly over time . Early in the disease , the most obvious are shaking , rigidity , slowness of movement , and difficulty with walking . Thinking and behavioral problems may also occur . Dementia becomes common in the advanced stages of the disease . Depression and anxiety are also common occurring in more than a third of people with PD . Other symptoms include sensory , sleep , and emotional problems . The main motor symptoms are collectively called `` parkinsonism '' , or a `` parkinsonian syndrome '' .   The cause of Parkinson 's disease is generally unknown , but believed to involve both genetic and environmental factors . Those with a family member affected are more likely to get the disease themselves . There is also an increased risk in people exposed to certain pesticides and among those who have had prior head injuries while there is a reduced risk in tobacco smokers and those who drink coffee or tea . The motor symptoms of the disease result from the death of cells in the substantia nigra , a region of the midbrain . This results in not enough dopamine in these areas . The reason for this cell death is poorly understood , but involves the build-up of proteins into Lewy bodies in the neurons . Diagnosis of typical cases is mainly based on symptoms , with tests such as neuroimaging being used to rule out other diseases .   There is no cure for Parkinson 's disease . Initial treatment is typically with the antiparkinson medication L-DOPA ( levodopa ) , with dopamine agonists being used once levodopa becomes less effective . As the disease progresses and neurons continue to be lost , these medications become less effective while at the same time they produce a complication marked by involuntary writhing movements . Diet and some forms of rehabilitation have shown some effectiveness at improving symptoms . Surgery to place microelectrodes for deep brain stimulation has been used to reduce motor symptoms in severe cases where drugs are ineffective . Evidence for treatments for the non-movement-related symptoms of PD , such as sleep disturbances and emotional problems , is less strong .   In 2015 , PD affected 6.2 million people and resulted in about 117,400 deaths globally . Parkinson 's disease typically occurs in people over the age of 60 , of which about one percent are affected . Males are more often affected than females . When it is seen in people before the age of 50 , it is called young-onset PD . The average life expectancy following diagnosis is between 7 and 14 years . The disease is named after the English doctor James Parkinson , who published the first detailed description in An Essay on the Shaking Palsy , in 1817 . Public awareness campaigns include World Parkinson 's Day ( on the birthday of James Parkinson , 11 April ) and the use of a red tulip as the symbol of the disease . People with parkinsonism who have increased the public 's awareness of the condition include actor Michael J. Fox , Olympic cyclist Davis Phinney , and late professional boxer Muhammad Ali .

neg: Human pathogen A human pathogen is a pathogen ( microbe or microorganism such as a virus , bacterium , prion , or fungus ) that causes disease in humans .   The human physiological defense against common pathogens ( such as Pneumocystis ) is mainly the responsibility of the immune system with help by some of the body 's normal flora and fauna . However , if the immune system or `` good '' microbiota are damaged in any way ( such as by chemotherapy , human immunodeficiency virus ( HIV ) , or antibiotics being taken to kill other pathogens ) , pathogenic bacteria that were being held at bay can proliferate and cause harm to the host . Such cases are called opportunistic infections .   Some pathogens ( such as the bacterium Yersinia pestis , which may have caused the Black Plague , the Variola virus , and the malaria protozoa ) have been responsible for massive numbers of casualties and have had numerous effects on afflicted groups . Of particular note in modern times is HIV , which is known to have infected several million humans globally , along with the influenza virus . Today , while many medical advances have been made to safeguard against infection by pathogens , through the use of vaccination , antibiotics , and fungicide , pathogens continue to threaten human life . Social advances such as food safety , hygiene , and water treatment have reduced the threat from some pathogens .

neg: Stroke in China Recent epidemiologic studies confirm that stroke is the most frequent cause of death in the People 's Republic of China , with an incidence more than fivefold that of myocardial infarction . Intracerebral hemorrhage causes about one third of all strokes , nearly three times the frequency in North American stroke registries . A marked regional variation in stroke incidence exists , with a threefold higher stroke incidence in northern than in southern Chinese cities , suggesting important environmental or dietary influences . Stroke treatment often involves a combination of modern and traditional herbal medicine ; the latter may modify platelet aggregation and blood viscosity . Stroke , particularly intracerebral hemorrhage , is the most frequent and important vascular disorder in China .   China reports more patients with stroke than anywhere else in the world . While there is still a great deal of unknown information , stroke research has been making great progress in recent years , such as in the areas of clinical research , population and genetic epidemiology , brain ischemia/reperfusion exploring , leukoencephalopathy ( CADASIL ) , neural stem cell and stroke , neuroprotective treatment for stroke , clinical therapy test in stroke , rehabilitation and prevention .   Cities and towns in China have integrated systems for registering and investigating strokes . Chinese researchers have followed closely the international level of stroke treatment with a forward position in neural stem cell . Traditional Chinese drugs have featured effects on neuroprotective treatment for stroke which has also been investigated . Chinese scientists have suggested a new way of dividing neuroprotectors in stroke . The clinical therapy test with urokinase and defibrase for cerebral infarction in China is effective and relatively safe , yet the original papers published by Chinese researchers and clinical effects for patient treatment still need to be improved and updated .

neg: Hand, foot, and mouth disease Hand , foot and mouth disease ( HFMD ) is a common infection caused by a group of viruses . It typically begins with a fever and feeling generally unwell . This is followed a day or two later by flat discolored spots or bumps that may blister , on the hands , feet , and mouth , and occasionally buttocks and groin . Signs and symptoms normally appear 3 -- 6 days after exposure to the virus . The rash generally goes away on its own in about a week . Fingernail and toenail loss may occur a few weeks later and these then regrow .   The viruses that cause HFMD are spread through close personal contact , through the air from coughing , and the feces of an infected person . Contaminated objects can also spread the disease . Coxsackievirus A16 is the most common cause and Enterovirus 71 is the second-most common cause . Other strains of coxsackievirus and enterovirus can also be responsible . Some people may carry and pass on the virus despite having no symptoms of disease . Other animals are not involved . Diagnosis can often be made based on symptoms . Occasionally throat or stool sample may be tested for the virus .   Handwashing may prevent spread and those infected should not go to work , daycare , or school . No antiviral medication or vaccine is available , but development efforts are underway . Most cases require no specific treatment . Simple pain medication such as ibuprofen or numbing mouth gel may be used . Occasionally intravenous fluids are given to children who are unable to drink enough . Rarely viral meningitis or encephalitis may complicate the disease .   HFMD occurs in all areas of the world . It often occurs in small outbreaks in nursery schools or kindergartens . Large outbreaks have been occurring in Asia since 1997 . It usually occurs during the spring , summer , and fall months . Typically it occurs in children less than five years old , but can occasionally occur in adults . HFMD should not be confused with foot-and-mouth disease ( also known as hoof-and-mouth disease ) which mostly affects livestock .

neg: Dermatitis herpetiformis Dermatitis herpetiformis ( DH ) , or Duhring 's disease , Freedberg , et al. ( 2003 ) . Fitzpatrick 's Dermatology in General Medicine . ( 6th ed . ) . McGraw-Hill . ISBN 0-07-138076-0 . is a chronic blistering skin condition , characterised by blisters filled with a watery fluid . Despite its name , DH is neither related to nor caused by herpes virus : the name means that it is a skin inflammation having an appearance similar to herpes .   DH was first described by Louis Adolphus Duhring in 1884 . A connection between DH and celiac disease was recognised in 1967 , although the exact causal mechanism is not known . DH is a specific manifestation of celiac disease .   The age of onset is usually about 15-40 , but DH can also affect children and the elderly . Men and women are equally affected . Estimates of DH prevalence vary from 1 in 400 to 1 in 10,000 . It is most common in patients of northern European/northern Indian ancestry , and is associated with the HLA-DQ2 haplotype along with coeliac disease and gluten sensitivity .

neg: Home care Home care ( also referred to as domiciliary care , social care , or in-home care ) is supportive care provided in the home . Care may be provided by licensed healthcare professionals who provide medical treatment needs or by professional caregivers who provide daily assistance to ensure the activities of daily living ( ADLs ) are met . In-home medical care is often and more accurately referred to as `` home health care '' or formal care . Often , the term home health care is used to distinguish it from non-medical care , custodial care , or private-duty care which refers to assistance and services provided by persons who are not nurses , doctors , or other licensed medical personnel . For terminally ill patients , home care may include hospice care . For patients recovering from surgery or illness , home care may include rehabilitative therapies .   Home health services help adults , seniors , and pediatric clients who are recovering after a hospital or facility stay , or need additional support to remain safely at home and avoid unnecessary hospitalization . These Medicare-certified services may include short-term nursing , rehabilitative , therapeutic , and assistive home health care . This care is provided by registered nurses ( RNs ) , licensed practical nurses ( LPN 's ) , physical therapists ( PTs ) , occupational therapists ( OTs ) , speech language pathologists ( SLPs ) , home health aides ( HHAs ) and medical social workers ( MSWs ) as a limited number of up to one hour visits , addressed primarily through the Medicare Home Health benefit .   The largest segment of home care consists of licensed and unlicensed non-medical personnel , including caregivers who assist the individual . Care assistants may help the individual with daily tasks such as bathing , eating , cleaning the home and preparing meals . Caregivers work to support the needs of individuals who require such assistance . These services help the client to stay at home versus living in a facility . Non-medical home care is paid for by the individual or family . The term `` private-duty '' refers to the private pay nature of these relationships . Home care ( non-medical ) has traditionally been privately funded as opposed to home health care which is task-based and government or insurance funded .   These traditional differences in home care services are changing as the average age of the population has risen . Individuals typically desire to remain independent and use home care services to maintain their existing lifestyle . Government and Insurance providers are beginning to fund this level of care as an alternative to facility care . In-Home Care is often a lower cost solution to long-term care facilities .

neg: Yellow fever vaccine Yellow fever vaccine is a vaccine that protects against yellow fever . Yellow fever is a viral infection that occurs in Africa and South America . Most people begin to develop immunity within ten days and 99 % are protected within one month of vaccination and this appears to be lifelong . The vaccine can be used to control outbreaks of disease . It is given either by injection into a muscle or just under the skin .   The World Health Organization ( WHO ) recommends routine immunization in all countries where the disease is common . This should typically occur between nine and twelve months of age . Those travelling to areas where the disease occurs should also be immunized . Additional doses after the first are generally not needed .   Yellow fever vaccine is generally safe . This includes in those with HIV infection but without symptoms . Mild side effects may include headache , muscle pains , pain at the injection site , fever , and rash . Severe allergies occur in about eight per million doses , serious neurological problems occur in about four per million doses , and organ failure occurs in about three per million doses . It is likely safe in pregnancy and therefore recommended among those who will be potentially exposed . It should not be given to those with very poor immune function .   Yellow fever vaccine came into use in 1938 . It is on the World Health Organization 's List of Essential Medicines , the most effective and safe medicines needed in a health system . The wholesale price in the developing world is between US$ 4.30 and US$ 21.30 per dose as of 2014 . In the United States it costs between US$ 50 and US$ 100 . The vaccine is made from weakened yellow fever virus . Some countries require a yellow fever vaccination certificate before entry from a country where the disease is common .

neg: Hypnodermatology Hypnodermatology is an informal label for the use of hypnosis in treating the skin conditions that fall between conventional medical dermatology and the mental health disciplines .   The use of hypnosis to provide relief for some skin conditions is based on observations that the severity of the disease may correlate with emotional issues . In addition , hypnotherapy has been used to suggest improvement on dermatological symptoms , such as chronic psoriasis , eczema , ichthyosis , warts and alopecia areata .   Philip D. Shenefelt , a research dermatologist at the University of South Florida School of Medicine , has identified two dozen dermatologic conditions that have shown response to hypnosis in the literature , with varying degrees of evidence . These include successful results in controlled trials on verruca vulgaris , psoriasis , and atopic dermatitis . A 2005 review in the Mayo Clinic Proceedings stated that , `` A review of the use of hypnosis in dermatology supports its value for many skin conditions not believed to be under conscious control '' . The most comprehensively studied skin conditions in relation to hypnotherapy are psoriasis and warts . Hypnosis may have positive effects on dermatological conditions in both adults and children .   Hypnotherapy may contribute towards reducing itching and discomfort brought on by the presence of warts and improves and possibly decreasing lesions .

neg: Pertussis Pertussis ( also known as whooping cough or 100-day cough ) is a highly contagious bacterial disease . Initially , symptoms are usually similar to those of the common cold with a runny nose , fever , and mild cough . This is then followed by weeks of severe coughing fits . Following a fit of coughing , a high-pitched whoop sound or gasp may occur as the person breathes in . The coughing may last for 10 or more weeks , hence the phrase `` 100-day cough '' . A person may cough so hard that they vomit , break ribs , or become very tired from the effort . Children less than one year old may have little or no cough and instead have periods where they do not breathe . The time between infection and the onset of symptoms is usually seven to ten days . Disease may occur in those who have been vaccinated , but symptoms are typically milder .   Pertussis is caused by the bacterium Bordetella pertussis . It is an airborne disease which spreads easily through the coughs and sneezes of an infected person . People are infectious to others from the start of symptoms until about three weeks into the coughing fits . Those treated with antibiotics are no longer infectious after five days . Diagnosis is by collecting a sample from the back of the nose and throat . This sample can then be tested by either culture or by polymerase chain reaction .   Prevention is mainly by vaccination with the pertussis vaccine . Initial immunization is recommended between six and eight weeks of age , with four doses to be given in the first two years of life . The vaccine becomes less effective over time , with additional doses often recommended for older children and adults . Antibiotics may be used to prevent the disease in those who have been exposed and are at risk of severe disease . In those with the disease , antibiotics are useful if started within three weeks of the initial symptoms , but otherwise have little effect in most people . In children less than one year old and among those who are pregnant , they are recommended within six weeks of symptom onset . Antibiotics used include erythromycin , azithromycin , clarithromycin , or trimethoprim/sulfamethoxazole . Evidence to support interventions , other than antibiotics , for the cough is poor . Many children less than a year of age require hospitalization .   An estimated 16.3 million people worldwide were infected in 2015 . Most cases occur in the developing world , and people of all ages may be affected . In 2015 , it resulted in 58,700 deaths -- down from 138,000 deaths in 1990 . Nearly 0.5 % of infected children less than one year of age die . Outbreaks of the disease were first described in the 16th century . The bacterium that causes the infection was discovered in 1906 . The pertussis vaccine became available in the 1940s .

neg: Schnitzler syndrome Schnitzler syndrome is a rare disease characterised by chronic hives ( urticaria ) and periodic fever , bone pain and joint pain ( sometimes with joint inflammation ) , weight loss , malaise , fatigue , swollen lymph glands and enlarged spleen and liver .   The urticarial rash is non-itching in more than half of cases , which is unusual for hives . It is most prominent on the trunk , arms and legs , sparing the palms , soles , head and neck . Associated angioedema has been reported in a few patients . A review of 94 cases found a mean age at onset of 51 years , and only four patients developed symptoms before the age of 35 . The cause and disease mechanism of Schnitzler syndrome remain largely unknown .   Schnitzler syndrome is considered an autoinflammatory and autoimmune disorder . Chronic hives and a monoclonal gammopathy have been proposed as the major criteria , while the others represent minor criteria .

neg: Irritable bowel syndrome Irritable bowel syndrome ( IBS ) is a group of symptoms -- including abdominal pain and changes in the pattern of bowel movements without any evidence of underlying damage . These symptoms occur over a long time , often years . It has been classified into four main types depending on if diarrhea is common , constipation is common , both are common , or neither occurs very often ( IBS-D , IBS-C , IBS-M , or IBS-U respectively ) . IBS negatively affects quality of life and may result in missed school or work . Disorders such as anxiety , major depression , and chronic fatigue syndrome are common among people with IBS .   The causes of IBS are not clear . Theories include gut -- brain axis problems , small intestinal bacterial overgrowth , genetic factors , food sensitivity , and gut motility problems . Onset may be triggered by an intestinal infection , or stressful life event . IBS is a functional gastrointestinal disorder . Diagnosis is based on signs and symptoms in the absence of worrisome features . Worrisome features include onset at greater than 50 years of age , weight loss , blood in the stool , or a family history of inflammatory bowel disease . Other conditions that may present similarly include celiac disease , microscopic colitis , inflammatory bowel disease , bile acid malabsorption , and colon cancer .   There is no cure for IBS . Treatment is carried out to improve symptoms . This may include dietary changes , medication , probiotics , and counseling . Dietary measures include increasing soluble fiber intake , a gluten free diet , or a diet low in fermentable oligosaccharides , disaccharides , monosaccharides , and polyols ( FODMAP ) . The medication loperamide may be used to help with diarrhea while laxatives may be used to help with constipation . Antidepressants may improve overall symptoms and pain . Patient education and a good doctor -- patient relationship are an important part of care .   About 10 to 15 % of people in the developed world are believed to be affected by IBS . It is more common in South America and less common in Southeast Asia . It is twice as common in women as men and typically occurs before age 45 . The condition appears to become less common with age . IBS does not affect life expectancy or lead to other serious diseases . The first description of the condition was in 1820 while the current term `` irritable bowel syndrome '' came into use in 1944 .

neg: Hypochondriasis Hypochondriasis , also known as hypochondria , health anxiety or illness anxiety disorder , refers to worry about having a serious illness . This debilitating condition is the result of an inaccurate perception of the condition of body or mind despite the absence of an actual medical condition . An individual suffering from hypochondriasis is known as a hypochondriac . Hypochondriacs become unduly alarmed about any physical or psychological symptoms they detect , no matter how minor the symptom may be , and are convinced that they have , or are about to be diagnosed with , a serious illness .   Often , hypochondria persists even after a physician has evaluated a person and reassured them that their concerns about symptoms do not have an underlying medical basis or , if there is a medical illness , their concerns are far in excess of what is appropriate for the level of disease . Many hypochondriacs focus on a particular symptom as the catalyst of their worrying , such as gastro-intestinal problems , palpitations , or muscle fatigue . To qualify for the diagnosis of hypochondria the symptoms must have been experienced for at least 6 months .   The DSM-IV-TR defines this disorder , `` Hypochondriasis '' , as a somatoform disorder and one study has shown it to affect about 3 % of the visitors to primary care settings . The newly published DSM-5 replaces the diagnosis of hypochondriasis with the diagnoses of `` somatic symptom disorder '' and `` illness anxiety disorder '' .   Hypochondria is often characterized by fears that minor bodily or mental symptoms may indicate a serious illness , constant self-examination and self-diagnosis , and a preoccupation with one 's body . Many individuals with hypochondriasis express doubt and disbelief in the doctors ' diagnosis , and report that doctors ' reassurance about an absence of a serious medical condition is unconvincing , or short-lasting . Additionally , many hypochondriacs experience elevated blood pressure , stress , and anxiety in the presence of doctors or while occupying a medical facility , a condition known as `` white coat syndrome '' . Many hypochondriacs require constant reassurance , either from doctors , family , or friends , and the disorder can become a disabling torment for the individual with hypochondriasis , as well as his or her family and friends . Some hypochondriacal individuals completely avoid any reminder of illness , whereas others frequently visit medical facilities , sometimes obsessively . Some sufferers may never speak about it .

neg: Kaposi's sarcoma Kaposi 's sarcoma or Kaposi sarcoma ( -LSB- ˈkæpəʃi_sɑrˈkoʊmə -RSB- KS ) is a tumor caused by infection with human herpesvirus 8 ( HHV8 ) , also known as Kaposi sarcoma-associated herpesvirus ( KSHV ) or KS agent . It was originally described by Moritz Kaposi , a Hungarian dermatologist practicing at the University of Vienna in 1872 . It became more widely known as one of the AIDS-defining illnesses in the 1980s . The viral cause for this cancer was discovered in 1994 . Although KS is now well-established to be caused by a viral infection , there is widespread lack of awareness of this even among persons at risk for KSHV/HHV -8 infection .   Kaposi sarcoma ( KS ) is a systemic disease that can present with cutaneous lesions with or without internal involvement . Four subtypes have been described : Classic KS , affecting middle aged men of Mediterranean descent ; African endemic KS ; KS in iatrogenically immunosuppressed patients ; and AIDS-related KS . The erythematous to violaceous cutaneous lesions seen in KS have several morphologies : macular , patch , plaque , nodular , and exophytic . The cutaneous lesions can be solitary , localized or disseminated . KS can involve the oral cavity , lymph nodes , and viscera . Classic KS tends to be indolent , presenting with erythematous or violaceous patches on the lower extremities . African endemic KS and AIDS-related KS tend to be more aggressive . The AIDS-related KS lesions often rapidly progress to plaques and nodules affecting the upper trunk , face , and oral mucosa . The diagnosis can be made with a tissue biopsy and , if clinically indicated , internal imaging should be done .   Once the diagnosis of KS has been made , treatment is based on the subtype and the presence of localized versus systemic disease . Localized cutaneous disease can be treated with cryotherapy , intralesional injections of vinblastine , alitretinoin gel , radiotherapy , topical immunotherapy ( Imiquimod ) , or surgical excision . Extensive cutaneous disease or internal disease may require intravenous chemotherapy and immunotherapy . Discontinuation or reduction of immunosuppressive therapy is recommended when KS arises in the setting of iatrogenic immunosuppression . However , with AIDS-related KS , highly active antiretroviral therapy ( HAART ) has been shown to prevent , or induce regression of , KS . Some AIDS patients have complete resolution of the lesions and prolonged remission while continuing the therapy . Therefore , HAART should be considered first-line treatment for these patients , though they may require other treatments at the same time .

neg: Erythema chronicum migrans Erythema chronicum migrans ( New Latin , literally , `` chronic migrating redness '' ) refers to the rash often ( though not always ) seen in the early stage of Lyme disease . It can appear anywhere from one day to one month after a tick bite . This rash does not represent an allergic reaction to the bite , but rather an actual skin infection with the Lyme bacteria , Borrelia burgdorferi sensu lato . `` Erythema migrans is the only manifestation of Lyme disease in the United States that is sufficiently distinctive to allow clinical diagnosis in the absence of laboratory confirmation . '' It is a pathognomonic sign : a physician-identified rash warrants an instant diagnosis of Lyme disease and immediate treatment without further testing , even by the strict criteria of the Centers for Disease Control and Prevention . Such target lesions ( bull 's - eye rashes ) are characteristic of Borrelia infections , and no other pathogens are known that cause this form of rash .   A similar condition called Southern Tick Associated Rash Illness ( STARI ) produces a similar rash pattern although it develops more quickly and is smaller . The associated infectious agent has not been determined . Antibiotic treatment resolves the illness quickly .   This erythema is also sometimes called erythema migrans or EM . However , a less common meaning of the term `` erythema migrans '' is a mucosal condition of the tongue , also called geographic tongue .

neg: Pressure ulcer Pressure ulcers , also known as pressure sores , bedsores and decubitus ulcers , are localized damage to the skin and/or underlying tissue that usually occur over a bony prominence as a result of pressure , or pressure in combination with shear and/or friction . The most common sites are the skin overlying the sacrum , coccyx , heels or the hips , but other sites such as the elbows , knees , ankles , back of shoulders , or the back of the cranium can be affected .   Pressure ulcers occur due to pressure applied to soft tissue resulting in completely or partially obstructed blood flow to the soft tissue . Shear is also a cause , as it can pull on blood vessels that feed the skin . Pressure ulcers most commonly develop in individuals who are not moving about , such as those being bedridden or confined to a wheelchair . It is widely believed that other factors can influence the tolerance of skin for pressure and shear , thereby increasing the risk of pressure ulcer development .   These factors are protein-calorie malnutrition , microclimate ( skin wetness caused by sweating or incontinence ) , diseases that reduce blood flow to the skin , such as arteriosclerosis , or diseases that reduce the sensation in the skin , such as paralysis or neuropathy . The healing of pressure ulcers may be slowed by the age of the person , medical conditions ( such as arteriosclerosis , diabetes or infection ) , smoking or medications such as anti-inflammatory drugs .   Although often prevented and treatable if detected early , pressure ulcers can be very difficult to prevent in critically ill people , frail elders , individuals with impaired mobility such as wheelchair users ( especially where spinal injury is involved ) . Primary prevention is to redistribute pressure by regularly turning the person . The benefit of turning to avoid further sores is well documented since at least the 19th century . In addition to turning and re-positioning the person in the bed or wheelchair , eating a balanced diet with adequate protein and keeping the skin free from exposure to urine and stool is very important .   The rate of pressure ulcers in hospital settings is high ; the prevalence in European hospitals ranges from 8.3 % to 23 % and 26 % in Canadian healthcare settings . In 2013 , there were 29,000 documented deaths globally , up from 14,000 deaths in 1990 .


query: Emma is based on a book.

pos: Emma (1996 TV film) Jane Austen 's Emma is an adaptation of the 1815 novel of the same name . It was adapted for the British television network ITV in 1996 , directed by Diarmuid Lawrence and dramatised by Andrew Davies , the same year as Miramax 's film adaptation of Emma starring Gwyneth Paltrow . This production of Emma stars Kate Beckinsale as the title character , and also features Samantha Morton as Harriet Smith and Mark Strong as Mr. Knightley .   Davies had recently adapted another Austen novel as the successful 1995 television serial Pride and Prejudice for BBC when he proposed to adapt the novel Emma for the network . BBC had already made such an agreement with another screenwriter however , leading Davies to approach ITV .   Emma received generally positive reviews from critics , who believed it to be superior to the 1996 Miramax film . Most focused on Beckinsale 's performance as a positive highlight . It aired on ITV on the 24 November 1996 and garnered an estimated 12 million viewers . It also was broadcast on the American channel A&E in 16 February 1997 .

neg: Fortunes of War (TV series) Fortunes of War is a 1987 BBC television adaptation of Olivia Manning 's cycle of novels Fortunes of War . It stars Kenneth Branagh as Guy Pringle , lecturer in English Literature in Bucharest during the early part of the Second World War , and Emma Thompson as his wife Harriet . Kenneth Branagh and Emma Thompson met filming the TV series and married in real life . Other cast members included Ronald Pickup , Robert Stephens , Alan Bennett , Philip Madoc and Rupert Graves . The series stays relatively faithful to the original novels , with no notable departures from their plot .

neg: My Turn to Make the Tea My Turn to Make the Tea is the third semi-autobiographical book by the British author Monica Dickens . First published in 1951 by Michael Joseph , the book relates Dickens ' time working as a junior reporter on the Downingham Post in the fictional town of Downingham .   The book is important for revealing the obstacles faced by many early women reporters in the world of journalism .

neg: What Hetty Did What Hetty Did is the seventh novel by J.L. Carr , published in 1988 when he was 76 years old . The novel describes the experiences of an 18-year-old girl . Hetty Birtwisle has been brought up by adoptive parents in the Fens ; after a beating by her father , discovering that she was adopted , she flees to Birmingham where she has learnt she was born and alters her surname to Beauchamp .   Hetty Beauchamp comes across several characters from Carr 's other novels in the boarding house in which she lives , including Emma Foxberrow , a teacher in The Harpole Report and Edward Peplow , from A Day in Summer .   Carr was offered an advance of # 5,000 for the novel , including paperback rights , but as this was the same amount that he had been offered three years earlier for The Battle of Pollocks Crossing , he decided to publish it himself . The book was published in an edition of 2,850 copies and is the first novel published by The Quince Tree Press . As Carr usually offered to send his books post free , he included the price of postage in the price of the book , which had to be printed on the back . However he based postage mistakenly on the cost of sending a Penguin paperback , and What Hetty Did was printed on superior paper with card covers , so it was heavier than expected and he lost money on postage . However the book sold well at # 3.95 a copy and he soon had another 3,000 copies printed . The novel is still published by The Quince Tree Press .   The book is notable for the fact that he gave his name as James Carr on the spine and J.L. Carr on the front . Carr was christened Joseph Lloyd and adopted the name ` Jim ' or even ` James ' in his early 20s .   The story was adapted by Ellen Dryden for BBC Radio 4 's Woman 's Hour Drama in 2004 .

neg: Emma Bull Emma Bull ( born December 13 , 1954 ) is an American science fiction and fantasy author . Her novels include the Hugo - and Nebula-nominated Bone Dance and the urban fantasy War for the Oaks . She is also known for a series of anthologies set in Liavek , a shared universe that she created with her husband Will Shetterly . As a singer , songwriter , and guitarist , she has been a member of the Minneapolis-based folk/rock bands Cats Laughing and The Flash Girls .

neg: Emma Rees Emma Rees may refer to :  Emma L. E. Rees , British academic  The Emma Rees Case

neg: Iain Blair Iain Blair ( 12 August 1942 -- 3 July 2011 ) was a Scottish actor and author who , using the pen name Emma Blair wrote a series of romantic novels .

neg: Emma Nyra Emma Chukwugoziam Obi ( born July 18 , 1988 ) , professionally known by her stage name Emma Nyra , is an American-born Nigerian singer-songerwriter , actress and model .

neg: Emma Lou Thayne Emma Lou Warner Thayne ( October 22 , 1924 -- December 6 , 2014 ) was a Mormon poet and novelist , counted as one of the 75 most significant .   Thayne graduated from the University of Utah in 1945 . She would later return there to coach tennis and teach English . In the late 1960s , she completed a master 's degree at the University of Utah . She was on the faculty over 30 years . In 1949 , she married Mel Thayne ; they became the parents of five daughters .   Although Thayne worked primarily as a poet , she also wrote novels . Her first novel was Never Past the Gate , which was inspired by her summers growing up in Mount Aire Canyon . Thayne also served on the board directors for Deseret News . She was also a contributor to such magazines as Network , a woman 's magazine based in Salt Lake City , Exponent II and Utah Holiday . At age 90 , she died in Salt Lake City on December 6 , 2014 .   Thayne wrote the words to the hymn `` Where Can I Turn for Peace '' .

neg: Supper at Emmaus (disambiguation) Supper at Emmaus is an event in the Gospel of Luke .   Supper at Emmaus is also the name of :   Supper at Emmaus ( London ) ( Caravaggio ) hangs at the National Gallery , London  Supper at Emmaus ( Milan ) ( Caravaggio ) hangs at the Pinacoteca di Brera , Milan  a forgery of Vermeer by Han van Meegeren

neg: Magic (novel) Magic is a psychological horror novel written by William Goldman . It was published in the United States in August 1976 by Delacorte Press . In 1978 Richard Attenborough directed a feature film adaptation of the story that starred Anthony Hopkins and Ann-Margret .

neg: Hilary Bailey Hilary Bailey ( 19 September 1936 -- 19 January 2017 ) was a British writer , critic and editor . Bailey attended Newnham College , University of Cambridge , where she was a founder-member of the Cambridge University Women 's Union . She was born in Bromley , Kent .   Her books include Polly Put the Kettle On , Mrs Mulvaney , Hannie Richards and All the Days of My Life , with a heroine who suffers the fate of all women who step away from what 's expected of them . She wrote a biography of Vera Brittain , and sequels to Jane Eyre and The Turn of the Screw , a novel called Miles and Flora , which takes place some time after the original and resurrects one of the main characters . Bailey edited volumes 7-10 of the New Worlds Quarterly series , and was uncredited coauthor of The Black Corridor with Michael Moorcock , to whom she was married at the time .   She was editing North Sea Island , the sequel to Bailey 's book , Fifty-First State , when her heart stopped .   Hilary had three children , Sophie , Kate and Max and three grandchildren Alex , Tom and Bobby .

neg: Emmeline Emmeline , The Orphan of the Castle is the first novel written by English writer Charlotte Turner Smith ; it was published in 1788 . A Cinderella story in which the heroine stands outside the traditional economic structures of English society and ends up wealthy and happy , the novel is a fantasy . At the same time , it criticises the traditional marriage arrangements of the 18th century , which allowed women little choice and prioritised the needs of the family . Smith 's criticisms of marriage stemmed from her personal experience and several of the secondary characters are thinly veiled depictions of her family , a technique which both intrigued and repelled contemporary readers .   Emmeline comments on the 18th-century novel tradition , presenting reinterpretations of scenes from famous earlier works , such as Samuel Richardson 's Clarissa ( 1747 -- 48 ) . Moreover , the novel extends and develops the tradition of Gothic fiction . In combination with this , Smith 's style marks her as an early Romantic . Her characters learn about their identities from nature and her landscape descriptions are imbued with political messages about gender relations .   Smith had separated from her husband in 1787 and was forced to write to support herself and her children . She quickly began writing novels , which were profitable at the time . Emmeline was published a year later in 1788 ; the first edition sold out quickly . Smith 's novel was so successful that her publisher paid her more than he had initially promised . The novel was printed in the United States , translated into French , and issued several times during the 19th century .

neg: Finder (novel) Finder is a fantasy fiction novel written by Emma Bull and published in 1994 .

neg: Emma Parker Emma Parker ( fl 1809 -- 1817 ) , was a novelist residing in Wales and writing in English , of whom very little is known . Her epistolary novel Self-Deception explores the cultural and religious differences between the English and the French .

neg: Eleanor (novel) Eleanor is a novel by Mary Augusta Ward , first published in 1900 .

neg: The Last Days of Emma Blank The Last Days of Emma Blank ( De laatste dagen van Emma Blank ) is a 2009 Dutch comedy film directed by Alex van Warmerdam .

neg: Emma Garrett Emma Garrett ( c. 1846 -- 1893 ) was an American educator and advocate of teaching speech to the deaf . She established the Pennsylvania Institution for the Deaf and Dumb in Mount Airy , Philadelphia to teach the language to the deaf . She paired with sister , Mary Garrett and established their own school by getting a grant from the federal government . Her educational methods to find how best to fully teach a deaf student can be seen through the word method in teaching which she ultimately created and is still used in educational classrooms with deaf students . Through this she was able to change the lives of many deaf students and allow them a chance of education .

neg: Emma-Lee (song) `` Emma-Lee '' is the first single taken from Idol ( Sweden ) Johan Palm 's debut album My Antidote . It reached # 1 in the Swedish Singles Chart and was composed by British Singer-Songwriter Ashley Hicklin , Swedish writer-producer Mårten Eriksson and his partner Lina Eriksson .

neg: Emma Kaye Emma Kaye is the founder and CEO of a full funded startup venture called Bozza .   Emma has a number of seminal ( and enduring ) business and industry ventures to her name , and attained multiple professional accolades and leading-light endorsements in the course of a steadily evolving , outwardly mercurial-seeming career spanning only 15 years . She draws attention to the strong business underpinning of her work , pointing out that her involvement has twice had the result of giving sustainable business direction and African brand equity to a highly charged , emerging sector .

neg: Hood (novel) Hood is a novel written by Irish author Emma Donoghue in 1995 . The book was the recipient of the 1997 Stonewall Book Award and is heavily influenced by James Joyce 's Ulysses .